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The map label for this gene is ykgC [H]

Identifier: 108800108

GI number: 108800108

Start: 3332410

End: 3333789

Strand: Reverse

Name: ykgC [H]

Synonym: Mmcs_3142

Alternate gene names: 108800108

Gene position: 3333789-3332410 (Counterclockwise)

Preceding gene: 108800109

Following gene: 108800106

Centisome position: 58.43

GC content: 66.96

Gene sequence:

>1380_bases
ATGGACACGGAGCCAACGACATTCGATGCAATCATCATCGGTGCAGGGCAGGCCGGACCGCCGCTGGCCGGACGGCTGAC
CGAGGCCGGGCAGACGGTTGCCGTCATCGAACGCAAACTCGTCGGCGGCACCTGCGTGAACTACGGGTGCATCCCCACCA
AAACGCTTGTCGCCAGCGCACACGCGGCGCACCTGGCGCGGCGGGGCGCCGAATACGGTGTCGGCACCGGTGACGTGACC
GTCGACATGGCGAAGGTCAAGGCCCGCAAGGACAAGATCATGCTCGGCGACCGCGAGGGTGTCGAGTCGTGGCTGCAGGG
GATGGACGGGTGCACGTTCATCCGCGGGCACGCCCGGTTCGAGGATCCACACACCGTGCGGGTCGACGACCAGGTGCTCA
AGGCCGACCGCATCTACCTCAACGTCGGCGGCCGCGCCGTCGCCCCGGATCTGCCCGGGCTCTCGGACATCGACTACCTC
ACCAACGTGGGCATCCTCGACCTCGACACCCTGCCCGAGCACCTGGTCATCGTCGGCGGCAGCTACATCGCGCTGGAGTT
CGCTCAGATGTACCGCCGCTTCGGCGCCCGGGTGACGGTGCTCGAACACGGTCCGCGACTGACCTCCCGCGAAGACGAGG
ACGTCTCGGCGGCGATCAAGGACATCCTCGAAGCCGAGGGCATCGACATCGTCCTCGACGCCAAGGACATCCGATTTACC
AAGCGCGACAACGGATTCGATGTCGTCCCGCGCGACGGCGCCGCCCCGATCGCCGGCAGCCATTTGCTGATCGCGGTCGG
TAGGCAGCCCAACACCGACGACCTCGGACTCGACGCCGCCGGTGTGCAGACCGACGAGCGCGGTTACGTCGTCGTCGACG
ACCAGCTGCGCACCACCGCCGACCACATCTGGGCCATGGGGGACTGCAACGGCAAAGGTGCGTTCACCCACACCTCGTAC
AACGATTTCGAGATTGTCGCGGCGAACCTGCTCGACGACGACCCACGGCGCGTCAGCGACCGCGTCACCACCTACGCGCT
CTACATCGACCCGCCGCTCGGGCGCGCCGGAATGACTGCCGAGCAGGTCCGCAAGTCCGGGCGCAAAGCGCTGGTCGGCA
AGCGACCCATGACGCGCGTCGGCCGCGCCGTCGAGAAAGGCGAGACCCAGGGCTTCATGAAGGTCGTGGTCGACGCCGAC
ACCGAGGAGATCCTCGGGGCGGCCATCCTCGGTGTCGGAGGGGATGAGGTCGTGCACGCGATCCTCGACATCATGACGGC
CAAGAAGCCCTACACGGCCATCTCCCGCACCATGCACATCCACCCGACCGTCAGCGAACTGGTGCCGACGCTGTTGCAGG
ACCTCAAACCGCTGACGTGA

Upstream 100 bases:

>100_bases
GCCGCCAACCGCGGTCGCGACCTACCGATCGCGCTACTCGAGGACGTGGTCGCCGTGGTCGGCGGATTCGCCATCGCATG
GCTCGCCTCGGTGGTGTGAG

Downstream 100 bases:

>100_bases
CGCCGGCCGTCGTCACACCCACTGGACGAACTGCACGATGATGCCGTTGGGGTCCTCGAACTGGCAGTACCGCTCACCCC
ACGGTTCGGTCTCCGGGGCT

Product: mercuric reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MDTEPTTFDAIIIGAGQAGPPLAGRLTEAGQTVAVIERKLVGGTCVNYGCIPTKTLVASAHAAHLARRGAEYGVGTGDVT
VDMAKVKARKDKIMLGDREGVESWLQGMDGCTFIRGHARFEDPHTVRVDDQVLKADRIYLNVGGRAVAPDLPGLSDIDYL
TNVGILDLDTLPEHLVIVGGSYIALEFAQMYRRFGARVTVLEHGPRLTSREDEDVSAAIKDILEAEGIDIVLDAKDIRFT
KRDNGFDVVPRDGAAPIAGSHLLIAVGRQPNTDDLGLDAAGVQTDERGYVVVDDQLRTTADHIWAMGDCNGKGAFTHTSY
NDFEIVAANLLDDDPRRVSDRVTTYALYIDPPLGRAGMTAEQVRKSGRKALVGKRPMTRVGRAVEKGETQGFMKVVVDAD
TEEILGAAILGVGGDEVVHAILDIMTAKKPYTAISRTMHIHPTVSELVPTLLQDLKPLT

Sequences:

>Translated_459_residues
MDTEPTTFDAIIIGAGQAGPPLAGRLTEAGQTVAVIERKLVGGTCVNYGCIPTKTLVASAHAAHLARRGAEYGVGTGDVT
VDMAKVKARKDKIMLGDREGVESWLQGMDGCTFIRGHARFEDPHTVRVDDQVLKADRIYLNVGGRAVAPDLPGLSDIDYL
TNVGILDLDTLPEHLVIVGGSYIALEFAQMYRRFGARVTVLEHGPRLTSREDEDVSAAIKDILEAEGIDIVLDAKDIRFT
KRDNGFDVVPRDGAAPIAGSHLLIAVGRQPNTDDLGLDAAGVQTDERGYVVVDDQLRTTADHIWAMGDCNGKGAFTHTSY
NDFEIVAANLLDDDPRRVSDRVTTYALYIDPPLGRAGMTAEQVRKSGRKALVGKRPMTRVGRAVEKGETQGFMKVVVDAD
TEEILGAAILGVGGDEVVHAILDIMTAKKPYTAISRTMHIHPTVSELVPTLLQDLKPLT
>Mature_459_residues
MDTEPTTFDAIIIGAGQAGPPLAGRLTEAGQTVAVIERKLVGGTCVNYGCIPTKTLVASAHAAHLARRGAEYGVGTGDVT
VDMAKVKARKDKIMLGDREGVESWLQGMDGCTFIRGHARFEDPHTVRVDDQVLKADRIYLNVGGRAVAPDLPGLSDIDYL
TNVGILDLDTLPEHLVIVGGSYIALEFAQMYRRFGARVTVLEHGPRLTSREDEDVSAAIKDILEAEGIDIVLDAKDIRFT
KRDNGFDVVPRDGAAPIAGSHLLIAVGRQPNTDDLGLDAAGVQTDERGYVVVDDQLRTTADHIWAMGDCNGKGAFTHTSY
NDFEIVAANLLDDDPRRVSDRVTTYALYIDPPLGRAGMTAEQVRKSGRKALVGKRPMTRVGRAVEKGETQGFMKVVVDAD
TEEILGAAILGVGGDEVVHAILDIMTAKKPYTAISRTMHIHPTVSELVPTLLQDLKPLT

Specific function: Unknown

COG id: COG1249

COG function: function code C; Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI91199540, Length=463, Percent_Identity=27.4298056155508, Blast_Score=169, Evalue=5e-42,
Organism=Homo sapiens, GI50301238, Length=464, Percent_Identity=29.0948275862069, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI148277065, Length=437, Percent_Identity=22.883295194508, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI33519430, Length=437, Percent_Identity=22.883295194508, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI33519428, Length=437, Percent_Identity=22.883295194508, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI33519426, Length=437, Percent_Identity=22.883295194508, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI148277071, Length=437, Percent_Identity=22.883295194508, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI291045266, Length=440, Percent_Identity=22.9545454545455, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI22035672, Length=457, Percent_Identity=25.382932166302, Blast_Score=83, Evalue=6e-16,
Organism=Escherichia coli, GI87081717, Length=457, Percent_Identity=37.199124726477, Blast_Score=270, Evalue=1e-73,
Organism=Escherichia coli, GI1786307, Length=456, Percent_Identity=27.1929824561404, Blast_Score=179, Evalue=4e-46,
Organism=Escherichia coli, GI1789915, Length=436, Percent_Identity=29.5871559633028, Blast_Score=167, Evalue=9e-43,
Organism=Escherichia coli, GI87082354, Length=463, Percent_Identity=26.5658747300216, Blast_Score=143, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI32565766, Length=456, Percent_Identity=26.7543859649123, Blast_Score=155, Evalue=5e-38,
Organism=Caenorhabditis elegans, GI71983429, Length=457, Percent_Identity=28.6652078774617, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI71983419, Length=457, Percent_Identity=28.6652078774617, Blast_Score=139, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI17557007, Length=482, Percent_Identity=25.103734439834, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI71982272, Length=456, Percent_Identity=23.2456140350877, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17559934, Length=178, Percent_Identity=28.0898876404494, Blast_Score=65, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6321091, Length=463, Percent_Identity=30.4535637149028, Blast_Score=195, Evalue=2e-50,
Organism=Saccharomyces cerevisiae, GI6325166, Length=478, Percent_Identity=22.8033472803347, Blast_Score=107, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6325240, Length=479, Percent_Identity=23.1732776617954, Blast_Score=97, Evalue=4e-21,
Organism=Drosophila melanogaster, GI21358499, Length=454, Percent_Identity=28.8546255506608, Blast_Score=187, Evalue=2e-47,
Organism=Drosophila melanogaster, GI24640549, Length=471, Percent_Identity=24.8407643312102, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24640553, Length=471, Percent_Identity=24.8407643312102, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24640551, Length=471, Percent_Identity=24.8407643312102, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI17737741, Length=470, Percent_Identity=24.0425531914894, Blast_Score=92, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016156
- InterPro:   IPR013027
- InterPro:   IPR004099
- InterPro:   IPR012999
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2; PF02852 Pyr_redox_dim [H]

EC number: NA

Molecular weight: Translated: 49440; Mature: 49440

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS00076 PYRIDINE_REDOX_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTEPTTFDAIIIGAGQAGPPLAGRLTEAGQTVAVIERKLVGGTCVNYGCIPTKTLVASA
CCCCCCEEEEEEEECCCCCCCCCCHHHHCCCEEEHHHHHHCCCCEECCCCCCHHHHHHHH
HAAHLARRGAEYGVGTGDVTVDMAKVKARKDKIMLGDREGVESWLQGMDGCTFIRGHARF
HHHHHHHCCCCCCCCCCCEEEEHHHHHHCCCCEEECCHHHHHHHHHCCCCCEEEECCCCC
EDPHTVRVDDQVLKADRIYLNVGGRAVAPDLPGLSDIDYLTNVGILDLDTLPEHLVIVGG
CCCCEEEECHHHHCCCEEEEEECCEEECCCCCCCCCHHHHHCCCEEEECCCCCEEEEECC
SYIALEFAQMYRRFGARVTVLEHGPRLTSREDEDVSAAIKDILEAEGIDIVLDAKDIRFT
CHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCEEEE
KRDNGFDVVPRDGAAPIAGSHLLIAVGRQPNTDDLGLDAAGVQTDERGYVVVDDQLRTTA
ECCCCCEECCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHH
DHIWAMGDCNGKGAFTHTSYNDFEIVAANLLDDDPRRVSDRVTTYALYIDPPLGRAGMTA
HHEEEEECCCCCCCEEECCCCCEEEEEEECCCCCHHHHHCCEEEEEEEECCCCCCCCCCH
EQVRKSGRKALVGKRPMTRVGRAVEKGETQGFMKVVVDADTEEILGAAILGVGGDEVVHA
HHHHHCCCCEECCCCCHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHEECCCHHHHHHH
ILDIMTAKKPYTAISRTMHIHPTVSELVPTLLQDLKPLT
HHHHHHCCCCHHHHHCEEEECCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDTEPTTFDAIIIGAGQAGPPLAGRLTEAGQTVAVIERKLVGGTCVNYGCIPTKTLVASA
CCCCCCEEEEEEEECCCCCCCCCCHHHHCCCEEEHHHHHHCCCCEECCCCCCHHHHHHHH
HAAHLARRGAEYGVGTGDVTVDMAKVKARKDKIMLGDREGVESWLQGMDGCTFIRGHARF
HHHHHHHCCCCCCCCCCCEEEEHHHHHHCCCCEEECCHHHHHHHHHCCCCCEEEECCCCC
EDPHTVRVDDQVLKADRIYLNVGGRAVAPDLPGLSDIDYLTNVGILDLDTLPEHLVIVGG
CCCCEEEECHHHHCCCEEEEEECCEEECCCCCCCCCHHHHHCCCEEEECCCCCEEEEECC
SYIALEFAQMYRRFGARVTVLEHGPRLTSREDEDVSAAIKDILEAEGIDIVLDAKDIRFT
CHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCEEEE
KRDNGFDVVPRDGAAPIAGSHLLIAVGRQPNTDDLGLDAAGVQTDERGYVVVDDQLRTTA
ECCCCCEECCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHH
DHIWAMGDCNGKGAFTHTSYNDFEIVAANLLDDDPRRVSDRVTTYALYIDPPLGRAGMTA
HHEEEEECCCCCCCEEECCCCCEEEEEEECCCCCHHHHHCCEEEEEEEECCCCCCCCCCH
EQVRKSGRKALVGKRPMTRVGRAVEKGETQGFMKVVVDADTEEILGAAILGVGGDEVVHA
HHHHHCCCCEECCCCCHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHEECCCHHHHHHH
ILDIMTAKKPYTAISRTMHIHPTVSELVPTLLQDLKPLT
HHHHHHCCCCHHHHHCEEEECCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: FAD. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]