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The map label for this gene is udg [H]

Identifier: 108800079

GI number: 108800079

Start: 3293645

End: 3294967

Strand: Reverse

Name: udg [H]

Synonym: Mmcs_3113

Alternate gene names: 108800079

Gene position: 3294967-3293645 (Counterclockwise)

Preceding gene: 108800080

Following gene: 108800078

Centisome position: 57.75

GC content: 65.31

Gene sequence:

>1323_bases
ATGAGGCTGAGCGTTATCGGGACCGGATACCTCGGCGCGGTCCATGCGGCATGTATGGCCCGCCTCGGGCACGACGTCGT
CGCATTCGATACCGACGCGTCGAAGATCGCCAAGCTCTCCGCTGGGGCGTCCCCACTGTTCGAACCCGGACTCGACGAAC
TACTCACCGCTGAAATGGCCTCGGGGCGCCTGCGATTCACGCAATCGCCTGACGAGGCGGTGTCCGGGGCGTCCGTGCAC
TTCGTGTGTGTCGGCACTCCGCAACTGTCGGATTCGGATGCCGCCGACGTCAGTTTCGTCAACAGCGCGGTCGACATGAT
CGCGACACACGCCGACGGCGAAGGTCTCATCGTCGGGAAGTCGACCGTGCCGGTAGGGACGGCCCAGCGGCTCGACTCCG
AACTGGCCGCCAGGTCGCTGCCACACCGCATGGAGGTGGCGTGGAACCCCGAATTCCTGCGTGAGGGTAAGGCGATCGAG
GACACCCTGCAGCCCGACCGATTGGTGTTCGGAGTGACCTCCGAGTCCGCCGAGAAGACGCTGCGCGAGGTGTACGCCGA
ACTCCTCGACGCAGGTACGCCCTACCTCACCACGGACCTCGCGACCGCCGAGATGGTCAAGGTGGCCGCGAATTCCTTTC
TCGCAACCAAGATCTCGTTTATCAATGCCATGGCCGAGGTGTGCGAAGCCGTCGATGCCGATGTGGTGACACTCAGCGAG
GCGCTGGGATACGACAGCCGGATCGGGCGCAGATTCCTCAACGCCGGGCTCGGCTTCGGCGGTGGTTGTCTTCCGAAGGA
CATCCGCGCGTTCAGTGCCAGAGCCGGTGAGGTCGGCGCCTCCGCGGCGCTGACATTCCTGCACGAGGTCGACAAGATCA
ACATCCGCCGACGGGAGAAGGCGGTGTCGGTGGCGGGAGCGCTGCTCGGCGGGGACTTCCTCGGCAAGAACATCGCCGTG
CTGGGGGCGGCGTTCAAACCCGACAGCGACGACGTGCGGGACTCGCCGGCCCTCAACGTCGCGGCCGCCATGCACCTCAA
GGGCTCCTACGTCCGCGTGCACGACCCGAAGGCGATCGCCAACGCCAGAGCCAGGTTCCCCACGCTCACCTACTGTGAAA
GCGTTCAGGAGGCGTGCCAGAACGTCGATCTGATCGTGCTGGCCACCGAATGGGATGAATACCGCAATTTGGACCCGGTC
GCGCTCCGCTCGACCGTTCGGACACAGAGCCTGCTGGACACCCGCAACGCGCTCGATGCCGAACTCTGGTCGGGCGCCGG
TTGGCGGGTATACGGCCTGGGCCGAGGTCAGCTGAATGTCTGA

Upstream 100 bases:

>100_bases
ATGTCTAACATCTTGTTTCCAGGGGGAACGCGTTGACAGGACGCATCGCCGCCGCGCGCAGGACTTCTGAGAATCTATTC
GAGTGGGGGAGGGCCATCTC

Downstream 100 bases:

>100_bases
CGGGGCACTCGGCAGGCACGAAGTCGTCACGGTCCGGCTGGTTTGACGCCCTGCCGGCCGGTGGGGCGCTTGCGCACGAG
TTGACGGGGGGGATCTTGAC

Product: UDP-glucose 6-dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MRLSVIGTGYLGAVHAACMARLGHDVVAFDTDASKIAKLSAGASPLFEPGLDELLTAEMASGRLRFTQSPDEAVSGASVH
FVCVGTPQLSDSDAADVSFVNSAVDMIATHADGEGLIVGKSTVPVGTAQRLDSELAARSLPHRMEVAWNPEFLREGKAIE
DTLQPDRLVFGVTSESAEKTLREVYAELLDAGTPYLTTDLATAEMVKVAANSFLATKISFINAMAEVCEAVDADVVTLSE
ALGYDSRIGRRFLNAGLGFGGGCLPKDIRAFSARAGEVGASAALTFLHEVDKINIRRREKAVSVAGALLGGDFLGKNIAV
LGAAFKPDSDDVRDSPALNVAAAMHLKGSYVRVHDPKAIANARARFPTLTYCESVQEACQNVDLIVLATEWDEYRNLDPV
ALRSTVRTQSLLDTRNALDAELWSGAGWRVYGLGRGQLNV

Sequences:

>Translated_440_residues
MRLSVIGTGYLGAVHAACMARLGHDVVAFDTDASKIAKLSAGASPLFEPGLDELLTAEMASGRLRFTQSPDEAVSGASVH
FVCVGTPQLSDSDAADVSFVNSAVDMIATHADGEGLIVGKSTVPVGTAQRLDSELAARSLPHRMEVAWNPEFLREGKAIE
DTLQPDRLVFGVTSESAEKTLREVYAELLDAGTPYLTTDLATAEMVKVAANSFLATKISFINAMAEVCEAVDADVVTLSE
ALGYDSRIGRRFLNAGLGFGGGCLPKDIRAFSARAGEVGASAALTFLHEVDKINIRRREKAVSVAGALLGGDFLGKNIAV
LGAAFKPDSDDVRDSPALNVAAAMHLKGSYVRVHDPKAIANARARFPTLTYCESVQEACQNVDLIVLATEWDEYRNLDPV
ALRSTVRTQSLLDTRNALDAELWSGAGWRVYGLGRGQLNV
>Mature_440_residues
MRLSVIGTGYLGAVHAACMARLGHDVVAFDTDASKIAKLSAGASPLFEPGLDELLTAEMASGRLRFTQSPDEAVSGASVH
FVCVGTPQLSDSDAADVSFVNSAVDMIATHADGEGLIVGKSTVPVGTAQRLDSELAARSLPHRMEVAWNPEFLREGKAIE
DTLQPDRLVFGVTSESAEKTLREVYAELLDAGTPYLTTDLATAEMVKVAANSFLATKISFINAMAEVCEAVDADVVTLSE
ALGYDSRIGRRFLNAGLGFGGGCLPKDIRAFSARAGEVGASAALTFLHEVDKINIRRREKAVSVAGALLGGDFLGKNIAV
LGAAFKPDSDDVRDSPALNVAAAMHLKGSYVRVHDPKAIANARARFPTLTYCESVQEACQNVDLIVLATEWDEYRNLDPV
ALRSTVRTQSLLDTRNALDAELWSGAGWRVYGLGRGQLNV

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=463, Percent_Identity=29.5896328293737, Blast_Score=204, Evalue=1e-52,
Organism=Homo sapiens, GI296040438, Length=364, Percent_Identity=30.2197802197802, Blast_Score=168, Evalue=8e-42,
Organism=Homo sapiens, GI296040443, Length=308, Percent_Identity=30.8441558441558, Blast_Score=145, Evalue=6e-35,
Organism=Escherichia coli, GI1788340, Length=365, Percent_Identity=29.3150684931507, Blast_Score=145, Evalue=7e-36,
Organism=Escherichia coli, GI48994968, Length=416, Percent_Identity=25.4807692307692, Blast_Score=111, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17560350, Length=461, Percent_Identity=31.236442516269, Blast_Score=201, Evalue=5e-52,
Organism=Drosophila melanogaster, GI17136908, Length=461, Percent_Identity=32.3210412147505, Blast_Score=213, Evalue=3e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 46772; Mature: 46772

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLSVIGTGYLGAVHAACMARLGHDVVAFDTDASKIAKLSAGASPLFEPGLDELLTAEMA
CEEEEEECCHHHHHHHHHHHHHCCCEEEECCCHHHHHHHCCCCCCCCCCCHHHHHHHHHH
SGRLRFTQSPDEAVSGASVHFVCVGTPQLSDSDAADVSFVNSAVDMIATHADGEGLIVGK
CCCEEECCCCHHHCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEC
STVPVGTAQRLDSELAARSLPHRMEVAWNPEFLREGKAIEDTLQPDRLVFGVTSESAEKT
CCCCCCHHHHHHHHHHHHCCCCCEEEEECHHHHHCCCCHHHHCCCCEEEEEECCHHHHHH
LREVYAELLDAGTPYLTTDLATAEMVKVAANSFLATKISFINAMAEVCEAVDADVVTLSE
HHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
ALGYDSRIGRRFLNAGLGFGGGCLPKDIRAFSARAGEVGASAALTFLHEVDKINIRRREK
HHCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHH
AVSVAGALLGGDFLGKNIAVLGAAFKPDSDDVRDSPALNVAAAMHLKGSYVRVHDPKAIA
HHHHHHHHHCCHHHCCCEEEEEEECCCCCCCCCCCCCHHHEEEEEECCCEEEEECCHHHH
NARARFPTLTYCESVQEACQNVDLIVLATEWDEYRNLDPVALRSTVRTQSLLDTRNALDA
HHHHCCCHHHHHHHHHHHHCCCCEEEEEECCHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
ELWSGAGWRVYGLGRGQLNV
HHHCCCCEEEEEECCCCCCC
>Mature Secondary Structure
MRLSVIGTGYLGAVHAACMARLGHDVVAFDTDASKIAKLSAGASPLFEPGLDELLTAEMA
CEEEEEECCHHHHHHHHHHHHHCCCEEEECCCHHHHHHHCCCCCCCCCCCHHHHHHHHHH
SGRLRFTQSPDEAVSGASVHFVCVGTPQLSDSDAADVSFVNSAVDMIATHADGEGLIVGK
CCCEEECCCCHHHCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEC
STVPVGTAQRLDSELAARSLPHRMEVAWNPEFLREGKAIEDTLQPDRLVFGVTSESAEKT
CCCCCCHHHHHHHHHHHHCCCCCEEEEECHHHHHCCCCHHHHCCCCEEEEEECCHHHHHH
LREVYAELLDAGTPYLTTDLATAEMVKVAANSFLATKISFINAMAEVCEAVDADVVTLSE
HHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
ALGYDSRIGRRFLNAGLGFGGGCLPKDIRAFSARAGEVGASAALTFLHEVDKINIRRREK
HHCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHH
AVSVAGALLGGDFLGKNIAVLGAAFKPDSDDVRDSPALNVAAAMHLKGSYVRVHDPKAIA
HHHHHHHHHCCHHHCCCEEEEEEECCCCCCCCCCCCCHHHEEEEEECCCEEEEECCHHHH
NARARFPTLTYCESVQEACQNVDLIVLATEWDEYRNLDPVALRSTVRTQSLLDTRNALDA
HHHHCCCHHHHHHHHHHHHCCCCEEEEEECCHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
ELWSGAGWRVYGLGRGQLNV
HHHCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA