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The map label for this gene is bioD [H]

Identifier: 108800042

GI number: 108800042

Start: 3250054

End: 3250743

Strand: Reverse

Name: bioD [H]

Synonym: Mmcs_3076

Alternate gene names: 108800042

Gene position: 3250743-3250054 (Counterclockwise)

Preceding gene: 108800043

Following gene: 108800041

Centisome position: 56.98

GC content: 74.06

Gene sequence:

>690_bases
GTGAGCGTTCTCGTGATCACCGGCACCGACACCGGCGTCGGTAAGACCGTGGCCACCGCGGCGCTGGCCTGCGCCGCCCG
GGTGGCCGGGATCGACGTCGCGGTGTGCAAACCCGTTCAGACCGGAACCGGGCCGGTCGGTGGGACCGGCGACGACGACC
TCGTCGAGATCGGCCGGCTGGCCGGGGTCGACGCCCTGCATCCGGGTTGGCGCTATCCGGACCCGTTGGCGCCGGTGGCC
GCCGCGGAGCGGGCGGGCGCCGCCCTGCCGACGCGCGACGAGTTGATCGGCATGGTCCGCGCTGCGGACGCGCCGGGACG
GCTGACGCTGGTGGAGGGCGCGGGCGGGCTCCTCGTCGAACTCGGTCAGGACGCGGTCACCCTGCGCGACGTCGCCACCG
AACTCGACGCCCCCGTGCTGGTCGTCGTCGCACCGGGACTCGGCACCCTCAACCACACCGCGCTGACCCTGGAATCGCTT
GCCGCTCAGCATGTTCCGTGCGCCGGGCTGGTGATCGGCGCGTGGCCCGCTCAGCCGGGCGCGGCCGAGATCGACAACCG
CGACACGCTGGCGCGGTTGGCCCCGGTGCGCGCCGCGCTGCCTGCGGGCGTCGGTTCGGTCAGCCCGGTGGACTTCGAAC
GGATCAGCGCGACCGCATTCGACCCGAACTGGCTCGCGGGCCTGCTGTAG

Upstream 100 bases:

>100_bases
GCACCTCCCGGCTCCGCCTGACCGCGCGGGCGTCGCTGACCGACGACGACCTCGACACCGCCCGCCGGGTGCTGGCCGAC
GTGTTGACGGCGGCCCGCCG

Downstream 100 bases:

>100_bases
ATGGTCCACTCGGTGGAGTTGCTCTTCGACCCCGACACCGACGCGGCCGTGCGCCGGATCTGGGACGACCTGAGCGCCGC
CGGAGTGCGCAGTCAGGCCG

Product: dithiobiotin synthetase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MSVLVITGTDTGVGKTVATAALACAARVAGIDVAVCKPVQTGTGPVGGTGDDDLVEIGRLAGVDALHPGWRYPDPLAPVA
AAERAGAALPTRDELIGMVRAADAPGRLTLVEGAGGLLVELGQDAVTLRDVATELDAPVLVVVAPGLGTLNHTALTLESL
AAQHVPCAGLVIGAWPAQPGAAEIDNRDTLARLAPVRAALPAGVGSVSPVDFERISATAFDPNWLAGLL

Sequences:

>Translated_229_residues
MSVLVITGTDTGVGKTVATAALACAARVAGIDVAVCKPVQTGTGPVGGTGDDDLVEIGRLAGVDALHPGWRYPDPLAPVA
AAERAGAALPTRDELIGMVRAADAPGRLTLVEGAGGLLVELGQDAVTLRDVATELDAPVLVVVAPGLGTLNHTALTLESL
AAQHVPCAGLVIGAWPAQPGAAEIDNRDTLARLAPVRAALPAGVGSVSPVDFERISATAFDPNWLAGLL
>Mature_228_residues
SVLVITGTDTGVGKTVATAALACAARVAGIDVAVCKPVQTGTGPVGGTGDDDLVEIGRLAGVDALHPGWRYPDPLAPVAA
AERAGAALPTRDELIGMVRAADAPGRLTLVEGAGGLLVELGQDAVTLRDVATELDAPVLVVVAPGLGTLNHTALTLESLA
AQHVPCAGLVIGAWPAQPGAAEIDNRDTLARLAPVRAALPAGVGSVSPVDFERISATAFDPNWLAGLL

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786995, Length=201, Percent_Identity=33.3333333333333, Blast_Score=81, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472 [H]

Pfam domain/function: NA

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 22903; Mature: 22772

Theoretical pI: Translated: 4.31; Mature: 4.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLVITGTDTGVGKTVATAALACAARVAGIDVAVCKPVQTGTGPVGGTGDDDLVEIGRL
CEEEEEECCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHH
AGVDALHPGWRYPDPLAPVAAAERAGAALPTRDELIGMVRAADAPGRLTLVEGAGGLLVE
CCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCEEEEECCCCEEEE
LGQDAVTLRDVATELDAPVLVVVAPGLGTLNHTALTLESLAAQHVPCAGLVIGAWPAQPG
CCCCHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCC
AAEIDNRDTLARLAPVRAALPAGVGSVSPVDFERISATAFDPNWLAGLL
CCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHEEECCCCHHHHHCC
>Mature Secondary Structure 
SVLVITGTDTGVGKTVATAALACAARVAGIDVAVCKPVQTGTGPVGGTGDDDLVEIGRL
EEEEEECCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHH
AGVDALHPGWRYPDPLAPVAAAERAGAALPTRDELIGMVRAADAPGRLTLVEGAGGLLVE
CCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCEEEEECCCCEEEE
LGQDAVTLRDVATELDAPVLVVVAPGLGTLNHTALTLESLAAQHVPCAGLVIGAWPAQPG
CCCCHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCC
AAEIDNRDTLARLAPVRAALPAGVGSVSPVDFERISATAFDPNWLAGLL
CCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHEEECCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA