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The map label for this gene is pheS [H]

Identifier: 108799940

GI number: 108799940

Start: 3140414

End: 3141448

Strand: Reverse

Name: pheS [H]

Synonym: Mmcs_2974

Alternate gene names: 108799940

Gene position: 3141448-3140414 (Counterclockwise)

Preceding gene: 108799941

Following gene: 108799939

Centisome position: 55.06

GC content: 68.99

Gene sequence:

>1035_bases
ATGGCCGGAAACCTGTCTGAAGAGGCGTTGACCGAAGCGGTCGACGCGGCTCGCCTTGCGTTCGATTCGGCCGCGGACCT
CGACGCGCTCGCCCGGGCGAAGACCGAACACCTCGGGGACCGGTCGCCGATCGCCGTGGCGCGTCAGTCGCTGGGCAGCC
TGCCCAAGACGGAGCGCGCCGATGCCGGTAAACGCGTCAACGTCGCGCGGTCGGACGCCCAGCGCAGCTATGACGAGCGC
CTCGCGGAGCTGCGTGCCGAGCGCGACGCGGCGGTCCTGGTCGCCGAACGCATCGACGTCACGCTCCCCTCGACGCGACA
ACCGGTCGGTGCGCGCCACCCGATCACGATCCTGGCCGAGAACATCGCCGACACCTTCGTCGCGATGGGCTGGGAACTTG
CCGAGGGGCCAGAGGTCGAGACCGAACAGTTCAACTTCGACGCGCTGAACTTCCCGCCGGACCATCCGGCGCGCAGCGAA
CAGGACACGTTCTACGTCGCGCCCGACGGATCGCGTCAGGTGCTGCGCACGCACACCTCGCCGGTGCAGATCCGCGCCCT
GCTCGAACGCGATCTGCCGGTCTACATCATCTCGATCGGCCGCACGTTCCGCACCGACGAACTCGACGCCACCCACACAC
CGGTGTTCCACCAGGTCGAAGGGCTCGCCGTCGACCGCGGCCTGACCATGGCGCACCTGCGCGGCACCCTCGATGCGTTC
GCCCGCGCCCAGTTCGGCCCGCAGGGCGGCACCCGGTTCCGGCCGCACTTCTTCCCGTTCACCGAACCGTCGGCGGAGGT
CGACGTGTGGTTCCCCGGCAAGAAGGGCGGGCCCGGCTGGGTGGAGTGGGGCGGATGCGGCATGGTCAACCCGAACGTGC
TGCGCGCCTGCGGGATCGACCCCGACGAGTACTCCGGTTTCGCATTCGGTATGGGTTTGGAGCGAACATTGCAGTTCCGC
AACGGGATTCCCGACATGCGCGACATGGTCGAGGGTGACGTCCGGTTCTCGCTGCCCTTCGGGGTGGGCGCCTGA

Upstream 100 bases:

>100_bases
TCGGGGGAGGACTCCACCGACGACGACTCCTAGCGGGGAAACGGTCGCGAGGGCGGGTCGGGCGATCACCTATGATCGCC
GGGTGGCTGAGCAGCCCGGA

Downstream 100 bases:

>100_bases
TGCGGCTGCCGTACAGCTGGCTGCGCGAGGTCGTGGCTGCCGGCGCGCCCGGATGGGACGTGTCCGCCGAGGAGCTCGAG
CAGACCTTGATCCGCATCGG

Product: phenylalanyl-tRNA synthetase subunit alpha

Products: NA

Alternate protein names: Phenylalanine--tRNA ligase alpha chain; PheRS [H]

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MAGNLSEEALTEAVDAARLAFDSAADLDALARAKTEHLGDRSPIAVARQSLGSLPKTERADAGKRVNVARSDAQRSYDER
LAELRAERDAAVLVAERIDVTLPSTRQPVGARHPITILAENIADTFVAMGWELAEGPEVETEQFNFDALNFPPDHPARSE
QDTFYVAPDGSRQVLRTHTSPVQIRALLERDLPVYIISIGRTFRTDELDATHTPVFHQVEGLAVDRGLTMAHLRGTLDAF
ARAQFGPQGGTRFRPHFFPFTEPSAEVDVWFPGKKGGPGWVEWGGCGMVNPNVLRACGIDPDEYSGFAFGMGLERTLQFR
NGIPDMRDMVEGDVRFSLPFGVGA

Sequences:

>Translated_344_residues
MAGNLSEEALTEAVDAARLAFDSAADLDALARAKTEHLGDRSPIAVARQSLGSLPKTERADAGKRVNVARSDAQRSYDER
LAELRAERDAAVLVAERIDVTLPSTRQPVGARHPITILAENIADTFVAMGWELAEGPEVETEQFNFDALNFPPDHPARSE
QDTFYVAPDGSRQVLRTHTSPVQIRALLERDLPVYIISIGRTFRTDELDATHTPVFHQVEGLAVDRGLTMAHLRGTLDAF
ARAQFGPQGGTRFRPHFFPFTEPSAEVDVWFPGKKGGPGWVEWGGCGMVNPNVLRACGIDPDEYSGFAFGMGLERTLQFR
NGIPDMRDMVEGDVRFSLPFGVGA
>Mature_343_residues
AGNLSEEALTEAVDAARLAFDSAADLDALARAKTEHLGDRSPIAVARQSLGSLPKTERADAGKRVNVARSDAQRSYDERL
AELRAERDAAVLVAERIDVTLPSTRQPVGARHPITILAENIADTFVAMGWELAEGPEVETEQFNFDALNFPPDHPARSEQ
DTFYVAPDGSRQVLRTHTSPVQIRALLERDLPVYIISIGRTFRTDELDATHTPVFHQVEGLAVDRGLTMAHLRGTLDAFA
RAQFGPQGGTRFRPHFFPFTEPSAEVDVWFPGKKGGPGWVEWGGCGMVNPNVLRACGIDPDEYSGFAFGMGLERTLQFRN
GIPDMRDMVEGDVRFSLPFGVGA

Specific function: Unknown

COG id: COG0016

COG function: function code J; Phenylalanyl-tRNA synthetase alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha chain type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI4758340, Length=275, Percent_Identity=32.7272727272727, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI5729820, Length=277, Percent_Identity=28.8808664259928, Blast_Score=101, Evalue=1e-21,
Organism=Escherichia coli, GI1788007, Length=331, Percent_Identity=46.8277945619335, Blast_Score=281, Evalue=4e-77,
Organism=Caenorhabditis elegans, GI17508957, Length=275, Percent_Identity=32.3636363636364, Blast_Score=134, Evalue=8e-32,
Organism=Caenorhabditis elegans, GI32563657, Length=275, Percent_Identity=32.3636363636364, Blast_Score=134, Evalue=8e-32,
Organism=Caenorhabditis elegans, GI32566635, Length=311, Percent_Identity=30.2250803858521, Blast_Score=112, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6321087, Length=264, Percent_Identity=34.0909090909091, Blast_Score=132, Evalue=9e-32,
Organism=Saccharomyces cerevisiae, GI6325304, Length=285, Percent_Identity=28.4210526315789, Blast_Score=107, Evalue=3e-24,
Organism=Drosophila melanogaster, GI18858079, Length=271, Percent_Identity=32.4723247232472, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI17137424, Length=286, Percent_Identity=27.2727272727273, Blast_Score=101, Evalue=6e-22,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006195
- InterPro:   IPR004529
- InterPro:   IPR004188
- InterPro:   IPR022911
- InterPro:   IPR002319
- InterPro:   IPR010978 [H]

Pfam domain/function: PF02912 Phe_tRNA-synt_N; PF01409 tRNA-synt_2d [H]

EC number: =6.1.1.20 [H]

Molecular weight: Translated: 37686; Mature: 37554

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGNLSEEALTEAVDAARLAFDSAADLDALARAKTEHLGDRSPIAVARQSLGSLPKTERA
CCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHC
DAGKRVNVARSDAQRSYDERLAELRAERDAAVLVAERIDVTLPSTRQPVGARHPITILAE
CCCCEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCEEECCCCCCCCCCCCCHHHHHH
NIADTFVAMGWELAEGPEVETEQFNFDALNFPPDHPARSEQDTFYVAPDGSRQVLRTHTS
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHCCC
PVQIRALLERDLPVYIISIGRTFRTDELDATHTPVFHQVEGLAVDRGLTMAHLRGTLDAF
HHHHHHHHHCCCCEEEEEECCEECCCCCCCCCCCHHHHHCCEEECCCCHHHHHHHHHHHH
ARAQFGPQGGTRFRPHFFPFTEPSAEVDVWFPGKKGGPGWVEWGGCGMVNPNVLRACGID
HHHHCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCEEECCCCCCCCHHHEECCCC
PDEYSGFAFGMGLERTLQFRNGIPDMRDMVEGDVRFSLPFGVGA
HHHCCCEEECCCHHHHHHHHCCCCHHHHHHCCCEEEECCCCCCC
>Mature Secondary Structure 
AGNLSEEALTEAVDAARLAFDSAADLDALARAKTEHLGDRSPIAVARQSLGSLPKTERA
CCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHC
DAGKRVNVARSDAQRSYDERLAELRAERDAAVLVAERIDVTLPSTRQPVGARHPITILAE
CCCCEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCEEECCCCCCCCCCCCCHHHHHH
NIADTFVAMGWELAEGPEVETEQFNFDALNFPPDHPARSEQDTFYVAPDGSRQVLRTHTS
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHCCC
PVQIRALLERDLPVYIISIGRTFRTDELDATHTPVFHQVEGLAVDRGLTMAHLRGTLDAF
HHHHHHHHHCCCCEEEEEECCEECCCCCCCCCCCHHHHHCCEEECCCCHHHHHHHHHHHH
ARAQFGPQGGTRFRPHFFPFTEPSAEVDVWFPGKKGGPGWVEWGGCGMVNPNVLRACGID
HHHHCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCEEECCCCCCCCHHHEECCCC
PDEYSGFAFGMGLERTLQFRNGIPDMRDMVEGDVRFSLPFGVGA
HHHCCCEEECCCHHHHHHHHCCCCHHHHHHCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA