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The map label for this gene is 108799922

Identifier: 108799922

GI number: 108799922

Start: 3120199

End: 3120813

Strand: Reverse

Name: 108799922

Synonym: Mmcs_2956

Alternate gene names: NA

Gene position: 3120813-3120199 (Counterclockwise)

Preceding gene: 108799926

Following gene: 108799921

Centisome position: 54.7

GC content: 72.85

Gene sequence:

>615_bases
GTGGTGAGTGTGGAGCTGCTGCGGGTCGACCCCCTCACGGCGGCCCGTCGGTTGCTCGGTGCGGTGCTGACCTGCCGCGG
CGTCAGCGCGACGGTCGTCGAGGTCGAGGCATACGGCGGCCCACCCGACGGGCCGTGGCCGGACGCCGCCGCCCACTCGT
ATCGCGGTCCCGGCCCGCGGAATCAGGTGATGTTCGGCCCCGCAGGCAGGCTCTACACCTACCGCAGCCACGGCATTCAC
GTCTGCGCGAACGTGGCCTGCGCCGACGACGGGGTGGCGGCCGCCGTGCTGCTGCGCGCGGCTGTCATCGAATCGGGTCA
TGACGTCGTACAGCGCCGTCGCGGCGAGGCGGTGCGTGAGTCGGCGTTTGCCAGGGGTCCGGGAAACCTGTGCTCGGCGC
TGGGAATCACGATGGCGGACAACGGAATCGATGTGTTCGCCGAGGACAGCCCCGTCCACCTCCGGCTGGGTGAGGAGCAA
CCGTGCATCGCCGGGCCCCGGGTCGGGGTGAGCAAGGCCGCCGACCGGCCGTGGCGACTGTGGTTGGCCGGCCGGCCGGA
GGTGTCGGCGTACCGGCGCAGCCCGCGAGCTCCGGCACCGGGCGGCAGCGACTGA

Upstream 100 bases:

>100_bases
CCGCGGCGGCGTCGATCAATTCATCATCCGATGAAGTCATCATGTGATGAATATTTCTCCCCCGCGGTCGGCGGGGTCAA
GAGGGCGGGGCAGAATCGCG

Downstream 100 bases:

>100_bases
TCTCGGCGCGTACGGAAAGATCGAGGTATGAGCAGCATTCTCGACGAGTTGGACTGGCGCGGGCTGATCGCGCAATCGAC
CGACCGGGACGCACTGGCGG

Product: 3-methyladenine DNA glycosylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MVSVELLRVDPLTAARRLLGAVLTCRGVSATVVEVEAYGGPPDGPWPDAAAHSYRGPGPRNQVMFGPAGRLYTYRSHGIH
VCANVACADDGVAAAVLLRAAVIESGHDVVQRRRGEAVRESAFARGPGNLCSALGITMADNGIDVFAEDSPVHLRLGEEQ
PCIAGPRVGVSKAADRPWRLWLAGRPEVSAYRRSPRAPAPGGSD

Sequences:

>Translated_204_residues
MVSVELLRVDPLTAARRLLGAVLTCRGVSATVVEVEAYGGPPDGPWPDAAAHSYRGPGPRNQVMFGPAGRLYTYRSHGIH
VCANVACADDGVAAAVLLRAAVIESGHDVVQRRRGEAVRESAFARGPGNLCSALGITMADNGIDVFAEDSPVHLRLGEEQ
PCIAGPRVGVSKAADRPWRLWLAGRPEVSAYRRSPRAPAPGGSD
>Mature_204_residues
MVSVELLRVDPLTAARRLLGAVLTCRGVSATVVEVEAYGGPPDGPWPDAAAHSYRGPGPRNQVMFGPAGRLYTYRSHGIH
VCANVACADDGVAAAVLLRAAVIESGHDVVQRRRGEAVRESAFARGPGNLCSALGITMADNGIDVFAEDSPVHLRLGEEQ
PCIAGPRVGVSKAADRPWRLWLAGRPEVSAYRRSPRAPAPGGSD

Specific function: Unknown

COG id: COG2094

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA glycosylase MPG family

Homologues:

Organism=Homo sapiens, GI62632771, Length=213, Percent_Identity=31.924882629108, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI62632769, Length=213, Percent_Identity=31.924882629108, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI62632765, Length=213, Percent_Identity=31.924882629108, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): 3MGH_MYCSK (A1UH86)

Other databases:

- EMBL:   CP000518
- RefSeq:   YP_938984.1
- ProteinModelPortal:   A1UH86
- SMR:   A1UH86
- STRING:   A1UH86
- EnsemblBacteria:   EBMYCT00000056903
- GeneID:   4610833
- GenomeReviews:   CP000518_GR
- KEGG:   mkm:Mkms_3000
- eggNOG:   COG2094
- GeneTree:   EBGT00050000017493
- HOGENOM:   HBG664239
- OMA:   LCSGPGK
- ProtClustDB:   PRK00802
- BioCyc:   MSP189918:MKMS_3000-MONOMER
- HAMAP:   MF_00527
- InterPro:   IPR011034
- InterPro:   IPR003180
- Gene3D:   G3DSA:3.10.300.10
- PANTHER:   PTHR10429
- TIGRFAMs:   TIGR00567

Pfam domain/function: PF02245 Pur_DNA_glyco; SSF50486 FMT_C_like

EC number: 3.2.2.-

Molecular weight: Translated: 21482; Mature: 21482

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSVELLRVDPLTAARRLLGAVLTCRGVSATVVEVEAYGGPPDGPWPDAAAHSYRGPGPR
CCEEEEEEECCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCC
NQVMFGPAGRLYTYRSHGIHVCANVACADDGVAAAVLLRAAVIESGHDVVQRRRGEAVRE
CCEEECCCCCEEEEECCCEEEEEEEEECCCCHHHHHHHHHHHHHCCHHHHHHHHCHHHHH
SAFARGPGNLCSALGITMADNGIDVFAEDSPVHLRLGEEQPCIAGPRVGVSKAADRPWRL
HHHCCCCHHHHHHHCCEEECCCEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCEEE
WLAGRPEVSAYRRSPRAPAPGGSD
EECCCCCHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MVSVELLRVDPLTAARRLLGAVLTCRGVSATVVEVEAYGGPPDGPWPDAAAHSYRGPGPR
CCEEEEEEECCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCC
NQVMFGPAGRLYTYRSHGIHVCANVACADDGVAAAVLLRAAVIESGHDVVQRRRGEAVRE
CCEEECCCCCEEEEECCCEEEEEEEEECCCCHHHHHHHHHHHHHCCHHHHHHHHCHHHHH
SAFARGPGNLCSALGITMADNGIDVFAEDSPVHLRLGEEQPCIAGPRVGVSKAADRPWRL
HHHCCCCHHHHHHHCCEEECCCEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCEEE
WLAGRPEVSAYRRSPRAPAPGGSD
EECCCCCHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA