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The map label for this gene is nagD [H]

Identifier: 108799919

GI number: 108799919

Start: 3111213

End: 3112217

Strand: Reverse

Name: nagD [H]

Synonym: Mmcs_2953

Alternate gene names: 108799919

Gene position: 3112217-3111213 (Counterclockwise)

Preceding gene: 108799920

Following gene: 108799918

Centisome position: 54.55

GC content: 72.84

Gene sequence:

>1005_bases
GTGCAGCAACATGATTGCCTGCTCCTCGATCTGGATGGCACGGTGTTCCGCGGCCACGAACCGACCACCGGAGCCGTCGA
GAGCCTCGCCGGGCTGAGCGCGCGGGTCCTCTACGTCACCAACAACGCCTCACGCAGCCCGGGCGACGTCGCAGGCCACC
TCGTCGAGTTGGGGTTCCACGCCGACGCCGCCGACGTGGTGACCAGCGCCCAGAGCGCAGCGCACCTGCTCGCCGCCCAA
CTTCCCGCCGGGGCGCGGGTGCTGGTCGTGGGCACCGAGGCGTTGGCGGCCGAGGTCGACCTCGTGGGACTGCAGCCGGT
CCGGCAGTTCGCCGACGATCCCGCCGCCGTTGTGCAGGGGCACAACCCGGAGACGGCGTGGGCGGACCTCGCCGAGGCGG
CGCTGGCCCTGCGCGCCGGGGCCCTGTGGGTGGCGGCCAATGTCGATCTGACCCTGCCGTCCGAGCGCGGACTGTTGCCT
GGCAACGGTTCGATGGTCGCCGCCCTGCAGGCCGCGACCGCCCGCGAACCTCAGGTCGCCGGCAAGCCGCAGCCGACGCT
GATGCGGGATGCGTTGAGCCGGGGCGACTTTCACACACCGCTGGTTGTCGGTGACCGTCTGGACACCGACATCGCCGGCG
CCAACGCGGCGTCGTTGCCGAGCCTGATGGTGCTCAGCGGTGTCAGCACCGCCGACGAGGTGCTGCGTGCGGTGCCCCAG
GAGCGGCCCGACTACATCGCCGAGGATCTGCGCTCCCTGGACGCACCGGCCGACGACCTGCGGGTCGGTCCCCACCCCGG
CTGGCGCATCGAGGTCGATGGCGCGGACGTGACCGTCCACGCCGACGGCGTCGACCGCGGGGACGACCTCTCGGTGCTGC
GTGCGACGGCCCACGTGGTGTGGCAGTCGGACCTGGCGGGCACGCCGTTCGCGGTCCGCGCGGGTGACGACACCGCGGCC
GCCGCGCTGCAACGGTGGTCGCTGCTCACCGCCGCGATCGACTAG

Upstream 100 bases:

>100_bases
GACGCCCTGCAGTGGTTCCTCAATGCCGCGGCCGCCGACGTGGAGGGCGTCACCGACGCCGAGGACCGGATCACGGAACT
CAGCTGACGTGACAGGCCTT

Downstream 100 bases:

>100_bases
CGTGGCGGTCGACATGAGTAACGACCCCGATCAGCTTCGCACCCGGGTCGCGGCCCTGCTCGCCGACCTGCCGGAACCGG
ACCACGCCGGTGACCTCGCC

Product: HAD family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MQQHDCLLLDLDGTVFRGHEPTTGAVESLAGLSARVLYVTNNASRSPGDVAGHLVELGFHADAADVVTSAQSAAHLLAAQ
LPAGARVLVVGTEALAAEVDLVGLQPVRQFADDPAAVVQGHNPETAWADLAEAALALRAGALWVAANVDLTLPSERGLLP
GNGSMVAALQAATAREPQVAGKPQPTLMRDALSRGDFHTPLVVGDRLDTDIAGANAASLPSLMVLSGVSTADEVLRAVPQ
ERPDYIAEDLRSLDAPADDLRVGPHPGWRIEVDGADVTVHADGVDRGDDLSVLRATAHVVWQSDLAGTPFAVRAGDDTAA
AALQRWSLLTAAID

Sequences:

>Translated_334_residues
MQQHDCLLLDLDGTVFRGHEPTTGAVESLAGLSARVLYVTNNASRSPGDVAGHLVELGFHADAADVVTSAQSAAHLLAAQ
LPAGARVLVVGTEALAAEVDLVGLQPVRQFADDPAAVVQGHNPETAWADLAEAALALRAGALWVAANVDLTLPSERGLLP
GNGSMVAALQAATAREPQVAGKPQPTLMRDALSRGDFHTPLVVGDRLDTDIAGANAASLPSLMVLSGVSTADEVLRAVPQ
ERPDYIAEDLRSLDAPADDLRVGPHPGWRIEVDGADVTVHADGVDRGDDLSVLRATAHVVWQSDLAGTPFAVRAGDDTAA
AALQRWSLLTAAID
>Mature_334_residues
MQQHDCLLLDLDGTVFRGHEPTTGAVESLAGLSARVLYVTNNASRSPGDVAGHLVELGFHADAADVVTSAQSAAHLLAAQ
LPAGARVLVVGTEALAAEVDLVGLQPVRQFADDPAAVVQGHNPETAWADLAEAALALRAGALWVAANVDLTLPSERGLLP
GNGSMVAALQAATAREPQVAGKPQPTLMRDALSRGDFHTPLVVGDRLDTDIAGANAASLPSLMVLSGVSTADEVLRAVPQ
ERPDYIAEDLRSLDAPADDLRVGPHPGWRIEVDGADVTVHADGVDRGDDLSVLRATAHVVWQSDLAGTPFAVRAGDDTAA
AALQRWSLLTAAID

Specific function: Unknown

COG id: COG0647

COG function: function code G; Predicted sugar phosphatases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. NagD family [H]

Homologues:

Organism=Homo sapiens, GI10092677, Length=250, Percent_Identity=34, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI108796653, Length=263, Percent_Identity=33.4600760456274, Blast_Score=96, Evalue=5e-20,
Organism=Escherichia coli, GI1786890, Length=253, Percent_Identity=29.6442687747036, Blast_Score=97, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17562458, Length=289, Percent_Identity=26.643598615917, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17560956, Length=289, Percent_Identity=26.643598615917, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17558880, Length=289, Percent_Identity=26.643598615917, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI193210059, Length=277, Percent_Identity=28.8808664259928, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI86563050, Length=245, Percent_Identity=29.7959183673469, Blast_Score=85, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6319965, Length=241, Percent_Identity=24.896265560166, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24666141, Length=265, Percent_Identity=27.9245283018868, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24656326, Length=268, Percent_Identity=26.4925373134328, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24656330, Length=281, Percent_Identity=25.9786476868327, Blast_Score=86, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006357
- InterPro:   IPR006354
- InterPro:   IPR023215 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: NA

Molecular weight: Translated: 34600; Mature: 34600

Theoretical pI: Translated: 4.31; Mature: 4.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQHDCLLLDLDGTVFRGHEPTTGAVESLAGLSARVLYVTNNASRSPGDVAGHLVELGFH
CCCCCEEEEECCCCEEECCCCCHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHEECCC
ADAADVVTSAQSAAHLLAAQLPAGARVLVVGTEALAAEVDLVGLQPVRQFADDPAAVVQG
CCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHEEEEECCHHHHHHCCCCHHEEEC
HNPETAWADLAEAALALRAGALWVAANVDLTLPSERGLLPGNGSMVAALQAATAREPQVA
CCCCHHHHHHHHHHHHHHCCEEEEEEEEEEECCCCCCCCCCCCCEEEEEEHHCCCCCCCC
GKPQPTLMRDALSRGDFHTPLVVGDRLDTDIAGANAASLPSLMVLSGVSTADEVLRAVPQ
CCCCCHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHCCC
ERPDYIAEDLRSLDAPADDLRVGPHPGWRIEVDGADVTVHADGVDRGDDLSVLRATAHVV
CCCHHHHHHHHHCCCCHHHCCCCCCCCCEEEECCCEEEEEECCCCCCCCHHHHHHHHHHE
WQSDLAGTPFAVRAGDDTAAAALQRWSLLTAAID
ECCCCCCCCEEEECCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQQHDCLLLDLDGTVFRGHEPTTGAVESLAGLSARVLYVTNNASRSPGDVAGHLVELGFH
CCCCCEEEEECCCCEEECCCCCHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHEECCC
ADAADVVTSAQSAAHLLAAQLPAGARVLVVGTEALAAEVDLVGLQPVRQFADDPAAVVQG
CCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHEEEEECCHHHHHHCCCCHHEEEC
HNPETAWADLAEAALALRAGALWVAANVDLTLPSERGLLPGNGSMVAALQAATAREPQVA
CCCCHHHHHHHHHHHHHHCCEEEEEEEEEEECCCCCCCCCCCCCEEEEEEHHCCCCCCCC
GKPQPTLMRDALSRGDFHTPLVVGDRLDTDIAGANAASLPSLMVLSGVSTADEVLRAVPQ
CCCCCHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHCCC
ERPDYIAEDLRSLDAPADDLRVGPHPGWRIEVDGADVTVHADGVDRGDDLSVLRATAHVV
CCCHHHHHHHHHCCCCHHHCCCCCCCCCEEEECCCEEEEEECCCCCCCCHHHHHHHHHHE
WQSDLAGTPFAVRAGDDTAAAALQRWSLLTAAID
ECCCCCCCCEEEECCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA