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The map label for this gene is ppnK [H]

Identifier: 108799916

GI number: 108799916

Start: 3109290

End: 3110213

Strand: Reverse

Name: ppnK [H]

Synonym: Mmcs_2950

Alternate gene names: 108799916

Gene position: 3110213-3109290 (Counterclockwise)

Preceding gene: 108799917

Following gene: 108799915

Centisome position: 54.51

GC content: 71.0

Gene sequence:

>924_bases
ATGACGTCTGAACGCACCATCCTGCTGGTGGTTCACACGGGACGCGAGGATGCCACCGATGTCGCCCGACGGGTGCAGAA
GATGTTGGGCGACAACGATATCGGTCTTCGGGTGCTCGCCGCCGAGGCGGTCGACCGGGGCCCGGTGCACCTGTCGCCCG
ACGATATGCGCGCGATCGGCGTCGACATCGACGTCGTCGACGCCGACGAACGGGCCGCCGAAGGCTGCGAGCTGGTGCTG
GTTCTCGGCGGCGACGGCACCTTCCTGCGCGCCGCCGAACTCGCGCGCAACGTCGAGATCCCGGTGCTGGGGGTGAACCT
CGGGCGGATCGGTTTCCTCGCCGAGGCCGAGGCGGAAGCCATCGACCGCGTACTCGAACACGTCGTCCGCCGCGACTACC
GCGTCGAGGAGAGGATGACCCTCGACGTGGCGGTGCGCGCGGAAGGGGAGCTCCTCACCCGGGGCTGGGCGCTCAACGAG
GCCAGCCTGGAGAAGGGGCCGCGCCTGGGGGTGCTCGGCGTGGTCGTGGAGATCGACGGCCGCCCGGTGTCGGCGTTCGG
CTGCGACGGTGTGCTGGTGTCGACGCCGACCGGGTCCACCGCTTACGCGTTCTCCGCCGGCGGGCCGGTGCTGTGGCCGG
ACCTCGAGGCGATCCTGGTGGTGCCCAACAACGCCCACGCCCTGTTCGCGCGGCCGATGGTGACCAGCCCGGACGCCACG
ATCGCGATCGAGATCGAGGCGAGCGGGCATGACGCCCTGGTGTTCTGCGACGGCCGGCGGGAGATGGTGGTGCCGGCCGG
TGGCCGGCTGGAGGTGACCCGCTGCGGCACACCGCTGAAGTGGGTACGGCTCGACAGCGCACCGTTCACCGACCGGCTGG
TGCGCAAGTTCCGGCTGCCCGTCACCGGATGGCGGGGGCAGTAG

Upstream 100 bases:

>100_bases
ACGTCGAGTACTTCTTGTGGTTACGCGCCCGCACGGACCGCGGACTGCGCGGCGACGATCTCGAGCAGGCGGTGCGGCGC
GCCGTCACGGAAGGACCGCA

Downstream 100 bases:

>100_bases
CGCCCGTGCTGTCCGAAATCCGCATCGAGTCCCTCGGCGCGATCAGCGCCGCCACCGCCGAATTCGACCGTGGTCTGACC
GTGCTCACCGGCGAGACCGG

Product: inorganic polyphosphate/ATP-NAD kinase

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase [H]

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MTSERTILLVVHTGREDATDVARRVQKMLGDNDIGLRVLAAEAVDRGPVHLSPDDMRAIGVDIDVVDADERAAEGCELVL
VLGGDGTFLRAAELARNVEIPVLGVNLGRIGFLAEAEAEAIDRVLEHVVRRDYRVEERMTLDVAVRAEGELLTRGWALNE
ASLEKGPRLGVLGVVVEIDGRPVSAFGCDGVLVSTPTGSTAYAFSAGGPVLWPDLEAILVVPNNAHALFARPMVTSPDAT
IAIEIEASGHDALVFCDGRREMVVPAGGRLEVTRCGTPLKWVRLDSAPFTDRLVRKFRLPVTGWRGQ

Sequences:

>Translated_307_residues
MTSERTILLVVHTGREDATDVARRVQKMLGDNDIGLRVLAAEAVDRGPVHLSPDDMRAIGVDIDVVDADERAAEGCELVL
VLGGDGTFLRAAELARNVEIPVLGVNLGRIGFLAEAEAEAIDRVLEHVVRRDYRVEERMTLDVAVRAEGELLTRGWALNE
ASLEKGPRLGVLGVVVEIDGRPVSAFGCDGVLVSTPTGSTAYAFSAGGPVLWPDLEAILVVPNNAHALFARPMVTSPDAT
IAIEIEASGHDALVFCDGRREMVVPAGGRLEVTRCGTPLKWVRLDSAPFTDRLVRKFRLPVTGWRGQ
>Mature_306_residues
TSERTILLVVHTGREDATDVARRVQKMLGDNDIGLRVLAAEAVDRGPVHLSPDDMRAIGVDIDVVDADERAAEGCELVLV
LGGDGTFLRAAELARNVEIPVLGVNLGRIGFLAEAEAEAIDRVLEHVVRRDYRVEERMTLDVAVRAEGELLTRGWALNEA
SLEKGPRLGVLGVVVEIDGRPVSAFGCDGVLVSTPTGSTAYAFSAGGPVLWPDLEAILVVPNNAHALFARPMVTSPDATI
AIEIEASGHDALVFCDGRREMVVPAGGRLEVTRCGTPLKWVRLDSAPFTDRLVRKFRLPVTGWRGQ

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus [H]

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family [H]

Homologues:

Organism=Homo sapiens, GI55743112, Length=230, Percent_Identity=30, Blast_Score=80, Evalue=3e-15,
Organism=Escherichia coli, GI1788968, Length=228, Percent_Identity=32.4561403508772, Blast_Score=120, Evalue=9e-29,
Organism=Saccharomyces cerevisiae, GI6322509, Length=243, Percent_Identity=27.9835390946502, Blast_Score=95, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6325068, Length=174, Percent_Identity=31.6091954022989, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6320794, Length=215, Percent_Identity=27.4418604651163, Blast_Score=91, Evalue=3e-19,
Organism=Drosophila melanogaster, GI161077047, Length=222, Percent_Identity=30.6306306306306, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28573826, Length=222, Percent_Identity=30.6306306306306, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28573832, Length=222, Percent_Identity=30.6306306306306, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28573830, Length=222, Percent_Identity=30.6306306306306, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28573828, Length=222, Percent_Identity=30.6306306306306, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI281363321, Length=247, Percent_Identity=27.1255060728745, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI20129957, Length=247, Percent_Identity=27.1255060728745, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24653422, Length=247, Percent_Identity=27.1255060728745, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI281363323, Length=290, Percent_Identity=25.8620689655172, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24653424, Length=247, Percent_Identity=27.1255060728745, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504 [H]

Pfam domain/function: PF01513 NAD_kinase [H]

EC number: =2.7.1.23 [H]

Molecular weight: Translated: 33069; Mature: 32938

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSERTILLVVHTGREDATDVARRVQKMLGDNDIGLRVLAAEAVDRGPVHLSPDDMRAIG
CCCCEEEEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEECCCCCEEEE
VDIDVVDADERAAEGCELVLVLGGDGTFLRAAELARNVEIPVLGVNLGRIGFLAEAEAEA
EEEEEEECCHHHCCCCEEEEEECCCCCEEEHHHHHCCCCCEEEEECCCCEEEEECCHHHH
IDRVLEHVVRRDYRVEERMTLDVAVRAEGELLTRGWALNEASLEKGPRLGVLGVVVEIDG
HHHHHHHHHHCCCCCCCEEEEEEEEECCCCEEECCEECCHHHHCCCCCEEEEEEEEEECC
RPVSAFGCDGVLVSTPTGSTAYAFSAGGPVLWPDLEAILVVPNNAHALFARPMVTSPDAT
EEEEEECCCEEEEECCCCCEEEEEECCCCEECCCCEEEEEECCCCCEEEECCEECCCCCE
IAIEIEASGHDALVFCDGRREMVVPAGGRLEVTRCGTPLKWVRLDSAPFTDRLVRKFRLP
EEEEEEECCCEEEEEECCCCEEEECCCCEEEEEECCCCEEEEEECCCCCHHHHHHHHCCC
VTGWRGQ
CCCCCCC
>Mature Secondary Structure 
TSERTILLVVHTGREDATDVARRVQKMLGDNDIGLRVLAAEAVDRGPVHLSPDDMRAIG
CCCEEEEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEECCCCCEEEE
VDIDVVDADERAAEGCELVLVLGGDGTFLRAAELARNVEIPVLGVNLGRIGFLAEAEAEA
EEEEEEECCHHHCCCCEEEEEECCCCCEEEHHHHHCCCCCEEEEECCCCEEEEECCHHHH
IDRVLEHVVRRDYRVEERMTLDVAVRAEGELLTRGWALNEASLEKGPRLGVLGVVVEIDG
HHHHHHHHHHCCCCCCCEEEEEEEEECCCCEEECCEECCHHHHCCCCCEEEEEEEEEECC
RPVSAFGCDGVLVSTPTGSTAYAFSAGGPVLWPDLEAILVVPNNAHALFARPMVTSPDAT
EEEEEECCCEEEEECCCCCEEEEEECCCCEECCCCEEEEEECCCCCEEEECCEECCCCCE
IAIEIEASGHDALVFCDGRREMVVPAGGRLEVTRCGTPLKWVRLDSAPFTDRLVRKFRLP
EEEEEEECCCEEEEEECCCCEEEECCCCEEEEEECCCCEEEEEECCCCCHHHHHHHHCCC
VTGWRGQ
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA