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The map label for this gene is xerD [H]

Identifier: 108799908

GI number: 108799908

Start: 3100811

End: 3101767

Strand: Reverse

Name: xerD [H]

Synonym: Mmcs_2942

Alternate gene names: 108799908

Gene position: 3101767-3100811 (Counterclockwise)

Preceding gene: 108799909

Following gene: 108799907

Centisome position: 54.37

GC content: 72.0

Gene sequence:

>957_bases
ATGGCCCCCTCAGCTGTTCGACGGTCGGCGCTCGACGATCAGCTGCAGGGCTACCTCGACCATCTGACCATCGAACGCGG
CGTCGCCGCGAACACGCTGAGCTCGTACCGCCGCGATCTGCGGCGCTATTCGGAGCACCTCACCGGCCGCGGGGTCGAGG
ACCTCGCGAAGGTCACCGAATCCGATGTCAGCGACTTCCTGGTCGCCCTGCGGCGCGGTGATCCCGACACCGGGGCCCAG
GCGCTGTCGGCGGTCTCGGCGGCGCGGGCGCTGATCGCGGTGCGGGGTCTGCACCGCTTCGCGACCGCCGAGGGGCTGAC
CGATGTCGACGTGGCCCGCGCGGTCAAACCGCCCACCCCCGGGCGCCGGTTGCCCAAGAGCCTGTCGATCGACGAAGTCC
TCGCACTCCTCGACGGCGCCGGAGGTGACAGCGAGGCCGACGGCCCCCTCACACTGCGTAACCGCGCACTGCTCGAACTG
CTGTACTCGACCGGCGCGCGGATCTCCGAAGCGGTCGGCCTCGACATCGACGACGTCGACACCCATGCGCGCTCTGTGCT
GCTGCGCGGCAAGGGCGGGAAGCAACGGCTGGTGCCGATCGGCAGGCCTGCGGTGAGCGCGCTGGACGCCTACCTGGTCC
GGGGGCGGCCGGATCTGGCCCGCCGCGGCCGCGGTACGCCGGCGATCTTCCTCAACGCGCGCGGGGGGCGGCTGTCGCGC
CAGAGCGCGTGGCAGGTGCTGCAGGACGCCGCCGAGCGGGCCGGGATCACGTCCGCGGTGTCGCCGCACACGTTGCGGCA
CTCCTTCGCGACCCATCTGCTCGATGGCGGCGCCGATGTGCGCGTCGTCCAGGAATTGCTCGGGCACGCCTCGGTGACCA
CGACGCAGATCTACACCATGGTGACGGTGCATGCGCTGCGCGAGGTGTGGGCGGGGGCGCATCCGCGGGCCCGGTGA

Upstream 100 bases:

>100_bases
ACGCCCTCGACGTCTCGGCACACGGTGTCGAGTCGCTGCGTCCGGTCGACGCGGAGTGGACCGACCGGCCACGCGCCTTC
GCCCGGCGGAAAGGTCACTG

Downstream 100 bases:

>100_bases
CCCACCGGTTGCGTCCGGTTGTGTGACGTCTCGGATGAACGGCATCTCGTCGTTAGATGCGGGAGTTATGGTCGGGGCGC
TCATTGGAGGTGACGGTGTG

Product: site-specific tyrosine recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 318; Mature: 317

Protein sequence:

>318_residues
MAPSAVRRSALDDQLQGYLDHLTIERGVAANTLSSYRRDLRRYSEHLTGRGVEDLAKVTESDVSDFLVALRRGDPDTGAQ
ALSAVSAARALIAVRGLHRFATAEGLTDVDVARAVKPPTPGRRLPKSLSIDEVLALLDGAGGDSEADGPLTLRNRALLEL
LYSTGARISEAVGLDIDDVDTHARSVLLRGKGGKQRLVPIGRPAVSALDAYLVRGRPDLARRGRGTPAIFLNARGGRLSR
QSAWQVLQDAAERAGITSAVSPHTLRHSFATHLLDGGADVRVVQELLGHASVTTTQIYTMVTVHALREVWAGAHPRAR

Sequences:

>Translated_318_residues
MAPSAVRRSALDDQLQGYLDHLTIERGVAANTLSSYRRDLRRYSEHLTGRGVEDLAKVTESDVSDFLVALRRGDPDTGAQ
ALSAVSAARALIAVRGLHRFATAEGLTDVDVARAVKPPTPGRRLPKSLSIDEVLALLDGAGGDSEADGPLTLRNRALLEL
LYSTGARISEAVGLDIDDVDTHARSVLLRGKGGKQRLVPIGRPAVSALDAYLVRGRPDLARRGRGTPAIFLNARGGRLSR
QSAWQVLQDAAERAGITSAVSPHTLRHSFATHLLDGGADVRVVQELLGHASVTTTQIYTMVTVHALREVWAGAHPRAR
>Mature_317_residues
APSAVRRSALDDQLQGYLDHLTIERGVAANTLSSYRRDLRRYSEHLTGRGVEDLAKVTESDVSDFLVALRRGDPDTGAQA
LSAVSAARALIAVRGLHRFATAEGLTDVDVARAVKPPTPGRRLPKSLSIDEVLALLDGAGGDSEADGPLTLRNRALLELL
YSTGARISEAVGLDIDDVDTHARSVLLRGKGGKQRLVPIGRPAVSALDAYLVRGRPDLARRGRGTPAIFLNARGGRLSRQ
SAWQVLQDAAERAGITSAVSPHTLRHSFATHLLDGGADVRVVQELLGHASVTTTQIYTMVTVHALREVWAGAHPRAR

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=304, Percent_Identity=42.1052631578947, Blast_Score=205, Evalue=4e-54,
Organism=Escherichia coli, GI1790244, Length=308, Percent_Identity=36.038961038961, Blast_Score=182, Evalue=3e-47,
Organism=Escherichia coli, GI1790767, Length=193, Percent_Identity=31.0880829015544, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790768, Length=175, Percent_Identity=33.1428571428571, Blast_Score=82, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 34065; Mature: 33934

Theoretical pI: Translated: 10.29; Mature: 10.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPSAVRRSALDDQLQGYLDHLTIERGVAANTLSSYRRDLRRYSEHLTGRGVEDLAKVTE
CCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
SDVSDFLVALRRGDPDTGAQALSAVSAARALIAVRGLHRFATAEGLTDVDVARAVKPPTP
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCC
GRRLPKSLSIDEVLALLDGAGGDSEADGPLTLRNRALLELLYSTGARISEAVGLDIDDVD
CCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHCCCCHHHH
THARSVLLRGKGGKQRLVPIGRPAVSALDAYLVRGRPDLARRGRGTPAIFLNARGGRLSR
HHHHHEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHCCCCCCEEEEECCCCCCCH
QSAWQVLQDAAERAGITSAVSPHTLRHSFATHLLDGGADVRVVQELLGHASVTTTQIYTM
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHH
VTVHALREVWAGAHPRAR
HHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
APSAVRRSALDDQLQGYLDHLTIERGVAANTLSSYRRDLRRYSEHLTGRGVEDLAKVTE
CCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
SDVSDFLVALRRGDPDTGAQALSAVSAARALIAVRGLHRFATAEGLTDVDVARAVKPPTP
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCC
GRRLPKSLSIDEVLALLDGAGGDSEADGPLTLRNRALLELLYSTGARISEAVGLDIDDVD
CCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHCCCCHHHH
THARSVLLRGKGGKQRLVPIGRPAVSALDAYLVRGRPDLARRGRGTPAIFLNARGGRLSR
HHHHHEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHCCCCCCEEEEECCCCCCCH
QSAWQVLQDAAERAGITSAVSPHTLRHSFATHLLDGGADVRVVQELLGHASVTTTQIYTM
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHH
VTVHALREVWAGAHPRAR
HHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]