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The map label for this gene is erg3 [H]

Identifier: 108799830

GI number: 108799830

Start: 3031318

End: 3032256

Strand: Reverse

Name: erg3 [H]

Synonym: Mmcs_2864

Alternate gene names: 108799830

Gene position: 3032256-3031318 (Counterclockwise)

Preceding gene: 108799831

Following gene: 108799829

Centisome position: 53.15

GC content: 65.39

Gene sequence:

>939_bases
ATGGGCGCAACGGGCGAAGCGGTTTCGGCGTTTCTGCAGTTCCTGCCGCCGCAGCTGCGCGAGCCGGTGCTGTTCGCGGT
CCCGTTCTTCTTGCTGCTGCTGATCCTCGAATGGACCGCCGCACGCAAACTCGAACACCTGGAATCCGGCGACCAACCGC
CTGCGGGCGCCTACGTCGCCCGTGATGCGTGGACCAGCCTCGCGATGGGCCTGGTCTCGGTCGGCACCATGGCGGTGTGG
AAGTTCGGCGCGCTGATCGGCTACGCGGCGCTGTACGCCTACGTCGCCCCGTGGCAGCTGCCGTCGAATCAGTGGTACAC
GTGGGTCATCGCGATCGTCGGTGTGGACCTGCTGTTCTACAGCTATCACCGCATCGCCCACCGGGTTCGGCTGGTCTGGG
CCACCCATCAGGCGCACCACTCCAGTGAGTACTACAACTTCGCCACCGCACTGCGCCAGAAGTGGAACAACAGCGGCGAG
ATCGTGATGTGGCTCCCGTTGCCGCTGCTGGGTGTGCCGCCGTGGATGGTGTTCGCCGGGTTCTCGATCAGCCTGATCTA
CCAGTTCTGGGTGCACACCGAACGGATCGGCACCATGTGGCGGCCGATCGAGTTCGTGTTCAACACGCCGTCGCACCACC
GCGTGCACCACGGCAGGGATCCGGAGTACCTGGACAAGAACTACGGGGGAATCCTGATCATCTGGGATCGCCTGTTCGGC
ACGTTCCAGCCGGAACTGTTCCGCCCGCACTACGGGCTGACCAAACCGGTGAACACCTACAACATCTGGCGGCTGCAGAC
CCACGAATACGCGGCCATCGCCCGCGACGTGCGCGGCGCGCGACGCTGGCGTGACCGACTCGGTTACGCGTTCGGCCCAC
CGGGGTGGAAACCGGTCGAGAACCGACACGTCGCGGAGAAGGCGGCGGTTCGCGCCTGA

Upstream 100 bases:

>100_bases
GTCGACGACCTCGACGGTGAGATCCGCGCCGCGTGGGGTGACGAGGTCCTCAGTTTCCGGTAGGGCGGGCGGCTAGACTC
CGGCTCGGAGGTGTCGGGTG

Downstream 100 bases:

>100_bases
TTTCGGTGCCGGCGCAGCAAGATGAACGCTATGGATGTCAAAGAGGTTCTGCTGCCCGGTGTCGGGCTGCGGTTCGAGTT
CGACAACCGCGACGGAGATC

Product: sterol desaturase-like protein

Products: NA

Alternate protein names: Sterol-C5-desaturase [H]

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MGATGEAVSAFLQFLPPQLREPVLFAVPFFLLLLILEWTAARKLEHLESGDQPPAGAYVARDAWTSLAMGLVSVGTMAVW
KFGALIGYAALYAYVAPWQLPSNQWYTWVIAIVGVDLLFYSYHRIAHRVRLVWATHQAHHSSEYYNFATALRQKWNNSGE
IVMWLPLPLLGVPPWMVFAGFSISLIYQFWVHTERIGTMWRPIEFVFNTPSHHRVHHGRDPEYLDKNYGGILIIWDRLFG
TFQPELFRPHYGLTKPVNTYNIWRLQTHEYAAIARDVRGARRWRDRLGYAFGPPGWKPVENRHVAEKAAVRA

Sequences:

>Translated_312_residues
MGATGEAVSAFLQFLPPQLREPVLFAVPFFLLLLILEWTAARKLEHLESGDQPPAGAYVARDAWTSLAMGLVSVGTMAVW
KFGALIGYAALYAYVAPWQLPSNQWYTWVIAIVGVDLLFYSYHRIAHRVRLVWATHQAHHSSEYYNFATALRQKWNNSGE
IVMWLPLPLLGVPPWMVFAGFSISLIYQFWVHTERIGTMWRPIEFVFNTPSHHRVHHGRDPEYLDKNYGGILIIWDRLFG
TFQPELFRPHYGLTKPVNTYNIWRLQTHEYAAIARDVRGARRWRDRLGYAFGPPGWKPVENRHVAEKAAVRA
>Mature_311_residues
GATGEAVSAFLQFLPPQLREPVLFAVPFFLLLLILEWTAARKLEHLESGDQPPAGAYVARDAWTSLAMGLVSVGTMAVWK
FGALIGYAALYAYVAPWQLPSNQWYTWVIAIVGVDLLFYSYHRIAHRVRLVWATHQAHHSSEYYNFATALRQKWNNSGEI
VMWLPLPLLGVPPWMVFAGFSISLIYQFWVHTERIGTMWRPIEFVFNTPSHHRVHHGRDPEYLDKNYGGILIIWDRLFGT
FQPELFRPHYGLTKPVNTYNIWRLQTHEYAAIARDVRGARRWRDRLGYAFGPPGWKPVENRHVAEKAAVRA

Specific function: Unknown

COG id: COG3000

COG function: function code I; Sterol desaturase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sterol desaturase family [H]

Homologues:

Organism=Homo sapiens, GI51972212, Length=278, Percent_Identity=38.4892086330935, Blast_Score=185, Evalue=5e-47,
Organism=Caenorhabditis elegans, GI25144659, Length=258, Percent_Identity=37.2093023255814, Blast_Score=165, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006694 [H]

Pfam domain/function: PF04116 FA_hydroxylase [H]

EC number: NA

Molecular weight: Translated: 35986; Mature: 35855

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGATGEAVSAFLQFLPPQLREPVLFAVPFFLLLLILEWTAARKLEHLESGDQPPAGAYVA
CCCCHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
RDAWTSLAMGLVSVGTMAVWKFGALIGYAALYAYVAPWQLPSNQWYTWVIAIVGVDLLFY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
SYHRIAHRVRLVWATHQAHHSSEYYNFATALRQKWNNSGEIVMWLPLPLLGVPPWMVFAG
HHHHHHHHHHHHEEHHHHHHCHHHHHHHHHHHHHHCCCCCEEEEECCCHHCCCHHHHHHC
FSISLIYQFWVHTERIGTMWRPIEFVFNTPSHHRVHHGRDPEYLDKNYGGILIIWDRLFG
CHHHHHHHHHHHHHHHHHHHCCHHEEECCCCCCCCCCCCCHHHHHCCCCCEEEEHHHHHC
TFQPELFRPHYGLTKPVNTYNIWRLQTHEYAAIARDVRGARRWRDRLGYAFGPPGWKPVE
CCCCHHCCCCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
NRHVAEKAAVRA
CCHHHHHHHCCC
>Mature Secondary Structure 
GATGEAVSAFLQFLPPQLREPVLFAVPFFLLLLILEWTAARKLEHLESGDQPPAGAYVA
CCCHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
RDAWTSLAMGLVSVGTMAVWKFGALIGYAALYAYVAPWQLPSNQWYTWVIAIVGVDLLFY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
SYHRIAHRVRLVWATHQAHHSSEYYNFATALRQKWNNSGEIVMWLPLPLLGVPPWMVFAG
HHHHHHHHHHHHEEHHHHHHCHHHHHHHHHHHHHHCCCCCEEEEECCCHHCCCHHHHHHC
FSISLIYQFWVHTERIGTMWRPIEFVFNTPSHHRVHHGRDPEYLDKNYGGILIIWDRLFG
CHHHHHHHHHHHHHHHHHHHCCHHEEECCCCCCCCCCCCCHHHHHCCCCCEEEEHHHHHC
TFQPELFRPHYGLTKPVNTYNIWRLQTHEYAAIARDVRGARRWRDRLGYAFGPPGWKPVE
CCCCHHCCCCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
NRHVAEKAAVRA
CCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]