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The map label for this gene is yhaU [H]

Identifier: 108799828

GI number: 108799828

Start: 3029605

End: 3030759

Strand: Reverse

Name: yhaU [H]

Synonym: Mmcs_2862

Alternate gene names: 108799828

Gene position: 3030759-3029605 (Counterclockwise)

Preceding gene: 108799829

Following gene: 108799827

Centisome position: 53.12

GC content: 71.34

Gene sequence:

>1155_bases
GTGGAGGTTTCGGCGACGCTGCTGCTCGAGCTCGGCGTGATCCTCGCTGCGCTCACCGTGCTCGGCACCATCGCCCGTCG
GTTCGCGCTCTCACCGATTCCGCTGTACCTGCTCGCCGGGCTCGCGGTGGGCGAGGGGGGACTGGCGCCGGTACCCGCGG
CCGGGGACTTCGTGGAGACCGGCGCGACGATCGGCGTCGTGCTGCTGCTGCTCACCCTCGGTCTGGAGTTCTCGATCGGG
GAGTTCGCGACCAGCCTGCGCAGGCACCTGCCGTCGGCCGGTGTCGACCTGGTCCTCAACGCAGCGCCCGGCGCCATCGC
CGGATGGCTGATCGGGTTGGACGGTGTCGGCATCCTGGCGCTGGCGGGTGTCACGTGGATCTCGTCGTCCGGCGTCATCG
CCCGGTTGCTGTCCGACCTCAGACGTCTCGGTAACCGCGAGACGCCCGCGGTGTTGTCGATCCTGGTGCTCGAGGATTTC
GCGATGGCGGCGTATCTCCCGTTGCTCGCGGTGCTCGCCACCGGTGGCACCTTCCTGCAGGCGCTGCTCGGGATGGCGAT
CGCGGTCAGCGCACTGGGCTTCGCGTTCGTGGTGTCCTACCGCTGGGGCCACCACGTCGGCCGTCTGGTCGTCCACCCGG
ACAACGAGCAGTTGCTGCTGCGCATCCTCGGGCTCACGCTCATCGTCGCGGCGCTGGCCGAGTTCATCCACGCGTCCGCG
GCGGTCGGTGCGTTCCTCGTCGGGCTGACGTTGACCGGGGAGGCGGCCGAACGGGCCCGCACCGTGCTCACCCCGCTGCG
GGATCTGTTCGCCGCCATCTTCTTCCTCGCGATCGGGGTGTCGGTGGACCCTGCTGCGCTGATCCCGATGCTGCCCGTCG
CGACGGCGCTGGCGGTCGCCACCGCCGCCACCAAGGTGCTGACCGGCCAGTTCGCCGCGCGGCGCGACGGGGTCGGCCGA
CCGGGTCAGCTGCGCGCGGGCACGGCGTTGATCGCGCGCGGTGAATTCTCGCTGGTGATCATCGGCCTCGTCGGTGCCAG
CGTGGAGGCGCTCGAAGCCGTGGCGACGCCGTATGTGTTCATCCTGGCCATGGTGGGCCCGGTGCTGGCGCGCTTCACCG
GTGGCCGGGCGCCCGCGCGCCGACGGCCCGGCTAG

Upstream 100 bases:

>100_bases
GATCGGGACCCACGAGGGCCTGGCCGGTGTAGAAGTCATCGTCAGCCAGGGGCACGGAGGCGAGGCGCACCAGCCCGGTC
CGCCCGGCCAAGGCTGATCG

Downstream 100 bases:

>100_bases
TCTCCGGCTGTGCAGACGGTATTCGACGCGCACGTCGACGCGACCCTCGTCGATGCGGCGCTCGCGCCCAGTGTCCCGGG
ATCGATGTGGCTCGATGTGC

Product: sodium/hydrogen exchanger

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MEVSATLLLELGVILAALTVLGTIARRFALSPIPLYLLAGLAVGEGGLAPVPAAGDFVETGATIGVVLLLLTLGLEFSIG
EFATSLRRHLPSAGVDLVLNAAPGAIAGWLIGLDGVGILALAGVTWISSSGVIARLLSDLRRLGNRETPAVLSILVLEDF
AMAAYLPLLAVLATGGTFLQALLGMAIAVSALGFAFVVSYRWGHHVGRLVVHPDNEQLLLRILGLTLIVAALAEFIHASA
AVGAFLVGLTLTGEAAERARTVLTPLRDLFAAIFFLAIGVSVDPAALIPMLPVATALAVATAATKVLTGQFAARRDGVGR
PGQLRAGTALIARGEFSLVIIGLVGASVEALEAVATPYVFILAMVGPVLARFTGGRAPARRRPG

Sequences:

>Translated_384_residues
MEVSATLLLELGVILAALTVLGTIARRFALSPIPLYLLAGLAVGEGGLAPVPAAGDFVETGATIGVVLLLLTLGLEFSIG
EFATSLRRHLPSAGVDLVLNAAPGAIAGWLIGLDGVGILALAGVTWISSSGVIARLLSDLRRLGNRETPAVLSILVLEDF
AMAAYLPLLAVLATGGTFLQALLGMAIAVSALGFAFVVSYRWGHHVGRLVVHPDNEQLLLRILGLTLIVAALAEFIHASA
AVGAFLVGLTLTGEAAERARTVLTPLRDLFAAIFFLAIGVSVDPAALIPMLPVATALAVATAATKVLTGQFAARRDGVGR
PGQLRAGTALIARGEFSLVIIGLVGASVEALEAVATPYVFILAMVGPVLARFTGGRAPARRRPG
>Mature_384_residues
MEVSATLLLELGVILAALTVLGTIARRFALSPIPLYLLAGLAVGEGGLAPVPAAGDFVETGATIGVVLLLLTLGLEFSIG
EFATSLRRHLPSAGVDLVLNAAPGAIAGWLIGLDGVGILALAGVTWISSSGVIARLLSDLRRLGNRETPAVLSILVLEDF
AMAAYLPLLAVLATGGTFLQALLGMAIAVSALGFAFVVSYRWGHHVGRLVVHPDNEQLLLRILGLTLIVAALAEFIHASA
AVGAFLVGLTLTGEAAERARTVLTPLRDLFAAIFFLAIGVSVDPAALIPMLPVATALAVATAATKVLTGQFAARRDGVGR
PGQLRAGTALIARGEFSLVIIGLVGASVEALEAVATPYVFILAMVGPVLARFTGGRAPARRRPG

Specific function: Potassium/proton antiporter that mediates the efflux of potassium ions from the cell. Potassium antiport activity requires the presence of khtT. Has higher activity at alkaline pH. Can also mediate rubidium/proton antiport. Has no permeability for sodium

COG id: COG0475

COG function: function code P; Kef-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell membrane [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family [H]

Homologues:

Organism=Escherichia coli, GI1786685, Length=349, Percent_Identity=29.7994269340974, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 39368; Mature: 39368

Theoretical pI: Translated: 8.99; Mature: 8.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVSATLLLELGVILAALTVLGTIARRFALSPIPLYLLAGLAVGEGGLAPVPAAGDFVET
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHC
GATIGVVLLLLTLGLEFSIGEFATSLRRHLPSAGVDLVLNAAPGAIAGWLIGLDGVGILA
CHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHCCCHHHHH
LAGVTWISSSGVIARLLSDLRRLGNRETPAVLSILVLEDFAMAAYLPLLAVLATGGTFLQ
HHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
ALLGMAIAVSALGFAFVVSYRWGHHVGRLVVHPDNEQLLLRILGLTLIVAALAEFIHASA
HHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AVGAFLVGLTLTGEAAERARTVLTPLRDLFAAIFFLAIGVSVDPAALIPMLPVATALAVA
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
TAATKVLTGQFAARRDGVGRPGQLRAGTALIARGEFSLVIIGLVGASVEALEAVATPYVF
HHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCEEEEEEHHCCHHHHHHHHHHHHHH
ILAMVGPVLARFTGGRAPARRRPG
HHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MEVSATLLLELGVILAALTVLGTIARRFALSPIPLYLLAGLAVGEGGLAPVPAAGDFVET
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHC
GATIGVVLLLLTLGLEFSIGEFATSLRRHLPSAGVDLVLNAAPGAIAGWLIGLDGVGILA
CHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHCCCHHHHH
LAGVTWISSSGVIARLLSDLRRLGNRETPAVLSILVLEDFAMAAYLPLLAVLATGGTFLQ
HHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
ALLGMAIAVSALGFAFVVSYRWGHHVGRLVVHPDNEQLLLRILGLTLIVAALAEFIHASA
HHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AVGAFLVGLTLTGEAAERARTVLTPLRDLFAAIFFLAIGVSVDPAALIPMLPVATALAVA
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
TAATKVLTGQFAARRDGVGRPGQLRAGTALIARGEFSLVIIGLVGASVEALEAVATPYVF
HHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCEEEEEEHHCCHHHHHHHHHHHHHH
ILAMVGPVLARFTGGRAPARRRPG
HHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]