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The map label for this gene is ppe42 [H]

Identifier: 108799791

GI number: 108799791

Start: 2973692

End: 2975320

Strand: Reverse

Name: ppe42 [H]

Synonym: Mmcs_2825

Alternate gene names: 108799791

Gene position: 2975320-2973692 (Counterclockwise)

Preceding gene: 108799793

Following gene: 108799790

Centisome position: 52.15

GC content: 61.2

Gene sequence:

>1629_bases
ATGAGAACGGCGTCATATCTGACCACTGGCGCCGCACTGCAAATCGTGACGCTCTTCGGCCTCGCGTACGCGACGGACAG
TCACCTTCCGGGCATCAGCCCGATGGCCGCCGTCTCGATTTTCATCGATGGCACCAAGGACATCCTCCCGACGACTGACA
GCCAGGATCCGGATCGGATGAAGGGCGCGCTCGACGGAGCGTTCGATCAATGTGCGACGAGCCCTTGCTCGGGGAAGAAC
GTCTTCATCAACTATCCGCGCGAGTTCGGCATCATGACCGGTCTAGGCAGCCATACCTACGACGACTCCAAGAGCATCGC
TGCTGAGGAGACCATCAAGGCGATCAAAGCTGCGAAGAGCGATCCCACATACCAGGCTGGCGACCCCATCTACGTCGTCG
GGTTCTCCCAGGGCGCGAACGCGGCATCGGACGTCATCGACCAATTGCGAAAGGACGGCTACGACGCATCAGGCGTGACG
TTCGTACTCTTGGGCAACGGCGCTCGCAACGATGGTGGCCTCTGGGCACGACTGCCTGCAGGAGTTTATGTTCCGTTGAT
TGGGCTCAGCTTCGGAGCCTCGACCAACCCCAGCTTGGATCCTAAAGCGCCACAGGTCATTCAGATCTCCAAGCAATATG
ACGGTGCTTCGGATGTGCCCAAGTACGTGATGAATCCGCTTGCATGGGCCAACGCCGCACTGGGCTTCATATACGTCCAC
AACGGCTACTACAACGATGTCGAGATCCCCGATGTGAACAACAACGGATTCGACCAAGCTGACATCGATGCATTGGAGGA
CAACCCGGATTACATCGTCACCAAGACCGGCAATGTCACCGACATTCTGATCAAGAACCCGGTCGGCCAGCTACCCCTCA
CCCGGCCGCTGTTGGATCTCGGAGTTCCACCCGAAATCGTCAGGGCTCTCGACCCGCTGCTGCGGGCCATCATCGAGACC
GGATACGACCGACCGACCGATGGCAAGTACGCCGCTACGCCAGTTCATCTCGAACTGATGCCCGACCCCCATCAGTGGGT
GGAGGACTTCCACGCCATCGCCGCGGGTATGGAGGAGACGCAGGAGAACCTCGCAGAGCTCAACCACGCCAACCTGATGC
AGAACAATATTCCTGAGCCCCAAACTCAGACGATCACTGCGTCGGGTACGGAGGAGAAGTCGGTTGTCGCCACCACTACC
ACCGGTGTGGTCACGACACCGAAGACGGGCGGAGAGACAGCCAGAACCGGTCCAGTTGGTGGACAGACCTGGTACAAGCC
GTTCACACCGGCGCCGGTGACTCAGGCTCCGCCGACCGCGACGGTACCGCCGACGACGCAACCGGTCACGCCGGTGGTGA
ATCAGGACCCGGCGCCCACGGGCGGGGAGGTCACGACGCCGAGCACGTCGAAACCGCAGGTGAACATCAACAAGTCCCTG
CAGCAGATCAACAAGGCGATCACGGGGACCGTGAACACCGTTGTCGGGGCGCTGACCCCGAAGCGTAGTGGTGGCACCAC
CACTACGCAGGATCCCAGCCCGTCGACGCAGGACCCGGGACCGACGGATACGGAGCCGAGTGGGGGGGGTACCGGCACCG
AGAGCAACAACGAGACCCCTGCCGCCTGA

Upstream 100 bases:

>100_bases
GCTACGCTGCTCGACACGCGGGTAACGAATTAGCCCGCATCGAGTAATACCGGGGTGGAGGACCAACGTGGGGAACCATC
GAGCAGAGGCTCGTAAGAAC

Downstream 100 bases:

>100_bases
AAACTGCATACCCACCCAAAGTGGTGCTGGGCCGTCAACGGCGGTCCAGCACCACTGCGGTGTCTCGAGAGGACTGACCC
TTGGAAATCGCACTGATCAT

Product: PE-PPE-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 542; Mature: 542

Protein sequence:

>542_residues
MRTASYLTTGAALQIVTLFGLAYATDSHLPGISPMAAVSIFIDGTKDILPTTDSQDPDRMKGALDGAFDQCATSPCSGKN
VFINYPREFGIMTGLGSHTYDDSKSIAAEETIKAIKAAKSDPTYQAGDPIYVVGFSQGANAASDVIDQLRKDGYDASGVT
FVLLGNGARNDGGLWARLPAGVYVPLIGLSFGASTNPSLDPKAPQVIQISKQYDGASDVPKYVMNPLAWANAALGFIYVH
NGYYNDVEIPDVNNNGFDQADIDALEDNPDYIVTKTGNVTDILIKNPVGQLPLTRPLLDLGVPPEIVRALDPLLRAIIET
GYDRPTDGKYAATPVHLELMPDPHQWVEDFHAIAAGMEETQENLAELNHANLMQNNIPEPQTQTITASGTEEKSVVATTT
TGVVTTPKTGGETARTGPVGGQTWYKPFTPAPVTQAPPTATVPPTTQPVTPVVNQDPAPTGGEVTTPSTSKPQVNINKSL
QQINKAITGTVNTVVGALTPKRSGGTTTTQDPSPSTQDPGPTDTEPSGGGTGTESNNETPAA

Sequences:

>Translated_542_residues
MRTASYLTTGAALQIVTLFGLAYATDSHLPGISPMAAVSIFIDGTKDILPTTDSQDPDRMKGALDGAFDQCATSPCSGKN
VFINYPREFGIMTGLGSHTYDDSKSIAAEETIKAIKAAKSDPTYQAGDPIYVVGFSQGANAASDVIDQLRKDGYDASGVT
FVLLGNGARNDGGLWARLPAGVYVPLIGLSFGASTNPSLDPKAPQVIQISKQYDGASDVPKYVMNPLAWANAALGFIYVH
NGYYNDVEIPDVNNNGFDQADIDALEDNPDYIVTKTGNVTDILIKNPVGQLPLTRPLLDLGVPPEIVRALDPLLRAIIET
GYDRPTDGKYAATPVHLELMPDPHQWVEDFHAIAAGMEETQENLAELNHANLMQNNIPEPQTQTITASGTEEKSVVATTT
TGVVTTPKTGGETARTGPVGGQTWYKPFTPAPVTQAPPTATVPPTTQPVTPVVNQDPAPTGGEVTTPSTSKPQVNINKSL
QQINKAITGTVNTVVGALTPKRSGGTTTTQDPSPSTQDPGPTDTEPSGGGTGTESNNETPAA
>Mature_542_residues
MRTASYLTTGAALQIVTLFGLAYATDSHLPGISPMAAVSIFIDGTKDILPTTDSQDPDRMKGALDGAFDQCATSPCSGKN
VFINYPREFGIMTGLGSHTYDDSKSIAAEETIKAIKAAKSDPTYQAGDPIYVVGFSQGANAASDVIDQLRKDGYDASGVT
FVLLGNGARNDGGLWARLPAGVYVPLIGLSFGASTNPSLDPKAPQVIQISKQYDGASDVPKYVMNPLAWANAALGFIYVH
NGYYNDVEIPDVNNNGFDQADIDALEDNPDYIVTKTGNVTDILIKNPVGQLPLTRPLLDLGVPPEIVRALDPLLRAIIET
GYDRPTDGKYAATPVHLELMPDPHQWVEDFHAIAAGMEETQENLAELNHANLMQNNIPEPQTQTITASGTEEKSVVATTT
TGVVTTPKTGGETARTGPVGGQTWYKPFTPAPVTQAPPTATVPPTTQPVTPVVNQDPAPTGGEVTTPSTSKPQVNINKSL
QQINKAITGTVNTVVGALTPKRSGGTTTTQDPSPSTQDPGPTDTEPSGGGTGTESNNETPAA

Specific function: Elicits a high humoral and a low T cell response. Could be involved in directing the host toward development of a more humoral type of immune response [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PPE family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002989
- InterPro:   IPR013228
- InterPro:   IPR000030 [H]

Pfam domain/function: PF08237 PE-PPE; PF01469 Pentapeptide_2; PF00823 PPE [H]

EC number: NA

Molecular weight: Translated: 56986; Mature: 56986

Theoretical pI: Translated: 4.30; Mature: 4.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTASYLTTGAALQIVTLFGLAYATDSHLPGISPMAAVSIFIDGTKDILPTTDSQDPDRM
CCCCHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCHHEEEEEECCCCCCCCCCCCCCHHHH
KGALDGAFDQCATSPCSGKNVFINYPREFGIMTGLGSHTYDDSKSIAAEETIKAIKAAKS
HHHHHHHHHHHCCCCCCCCEEEEECCHHHCCEECCCCCCCCCCHHHHHHHHHHHHHHHCC
DPTYQAGDPIYVVGFSQGANAASDVIDQLRKDGYDASGVTFVLLGNGARNDGGLWARLPA
CCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCEEEECCC
GVYVPLIGLSFGASTNPSLDPKAPQVIQISKQYDGASDVPKYVMNPLAWANAALGFIYVH
CEEEEEEEEECCCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHEEEEEEEE
NGYYNDVEIPDVNNNGFDQADIDALEDNPDYIVTKTGNVTDILIKNPVGQLPLTRPLLDL
CCCCCCEECCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEEEECCCCCCCCCCHHHHC
GVPPEIVRALDPLLRAIIETGYDRPTDGKYAATPVHLELMPDPHQWVEDFHAIAAGMEET
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEECEEEEEECCCHHHHHHHHHHHHHHHHHH
QENLAELNHANLMQNNIPEPQTQTITASGTEEKSVVATTTTGVVTTPKTGGETARTGPVG
HHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCEEEEEECCCEEECCCCCCCCCCCCCCC
GQTWYKPFTPAPVTQAPPTATVPPTTQPVTPVVNQDPAPTGGEVTTPSTSKPQVNINKSL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCEECHHHHH
QQINKAITGTVNTVVGALTPKRSGGTTTTQDPSPSTQDPGPTDTEPSGGGTGTESNNETP
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AA
CC
>Mature Secondary Structure
MRTASYLTTGAALQIVTLFGLAYATDSHLPGISPMAAVSIFIDGTKDILPTTDSQDPDRM
CCCCHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCHHEEEEEECCCCCCCCCCCCCCHHHH
KGALDGAFDQCATSPCSGKNVFINYPREFGIMTGLGSHTYDDSKSIAAEETIKAIKAAKS
HHHHHHHHHHHCCCCCCCCEEEEECCHHHCCEECCCCCCCCCCHHHHHHHHHHHHHHHCC
DPTYQAGDPIYVVGFSQGANAASDVIDQLRKDGYDASGVTFVLLGNGARNDGGLWARLPA
CCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCEEEECCC
GVYVPLIGLSFGASTNPSLDPKAPQVIQISKQYDGASDVPKYVMNPLAWANAALGFIYVH
CEEEEEEEEECCCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHEEEEEEEE
NGYYNDVEIPDVNNNGFDQADIDALEDNPDYIVTKTGNVTDILIKNPVGQLPLTRPLLDL
CCCCCCEECCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEEEECCCCCCCCCCHHHHC
GVPPEIVRALDPLLRAIIETGYDRPTDGKYAATPVHLELMPDPHQWVEDFHAIAAGMEET
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEECEEEEEECCCHHHHHHHHHHHHHHHHHH
QENLAELNHANLMQNNIPEPQTQTITASGTEEKSVVATTTTGVVTTPKTGGETARTGPVG
HHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCEEEEEECCCEEECCCCCCCCCCCCCCC
GQTWYKPFTPAPVTQAPPTATVPPTTQPVTPVVNQDPAPTGGEVTTPSTSKPQVNINKSL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCEECHHHHH
QQINKAITGTVNTVVGALTPKRSGGTTTTQDPSPSTQDPGPTDTEPSGGGTGTESNNETP
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AA
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]