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The map label for this gene is pimC [H]

Identifier: 108799714

GI number: 108799714

Start: 2892705

End: 2893871

Strand: Reverse

Name: pimC [H]

Synonym: Mmcs_2748

Alternate gene names: 108799714

Gene position: 2893871-2892705 (Counterclockwise)

Preceding gene: 108799716

Following gene: 108799713

Centisome position: 50.72

GC content: 70.52

Gene sequence:

>1167_bases
ATGCGTGGCCGCGCAACGCACAGAAGCGACCGGTTTCCTCGAGGCATGCGCGTGGTGCAGGTCGCCAACTTCTACGGGCC
ACGCTCGGGCGGCTTACGCACCGCGGTCGACCGGCTCGGCGCCGAGTACTGCGCGGCCGGACACGAGGTGTATCTCGTCG
TGCCCGGGCATCGCACCGAGCATCAGCGGTTGGCCACCGGCGTCACCCGAATCACCCTGCCCGCCCGCCTGATTCCCTTC
ACCGGCGGATATCGCGCCGTTCTGCCGGGTCCGGTCACCGCCCTGCTTCACGAGCTGCAACCCGATGCGATCGAGGTGTC
CGACCGACTGACGTTGCGCTCGCTCGGGGGATGGGGGCGACGCCACGGTGTGGCGACGGTGATGATCTCCCACGAACGCC
TCGACCGTCTCGTCGGGCAGGTCGTGCCGGGCCGCGTGGCTCGTGCGGTCGCCGATATCGCCAACCGCCGCACCGCGAGC
AACTACGACACCGTCGTCTGTACGACCGCGTTCGCGCGTAGGGAGTTCGACCGGATCGACGCCACCAACGTCGTCACCGT
TCCGCTCGGAGTCGACCTCGACCAGTTCCACCCGCGTCGACGGTCGGATCAGATGCGGCGGCGGTGGGCGGCTCCCGATC
AGACCCTCCTCGTGCACTGTGGCCGGCTGTCGGTAGAGAAGCATGCGCACCGCAGCATCGACGCCGTTGCGGCGCTGCGT
CATTCAGGTGTCGACGCGCGACTGGTCGTGGTGGGCGAGGGGCCGCTGCGGCAGCGCCTCGAACGCCAGGCCACCGGCCT
CCCCGTCGACTTCACGGGGTACATCGGCTGTCGCGACACCGTGGCGGGCATCCTCGCGTCCGCGGACGTGGCGCTCGCCC
CGGGACCGCACGAGACGTTCGGCCTCGCCGCACTCGAAGCGCTGGCCTGCGGAACCCCTGCCGTCGTGTCCCGTACCTCC
GCCCTCGCCGAGATCCTCACTGCAGACAGCGGAGCCGCCGCCGACAACGACCCGCAGGCGATCGCCGATGCCGTCGGACG
GGTGATCCGCGTACCGGAAACGGTGCGCCGGATCAACGCCCGGCGGCGCGCCGAGCAGTTCACGTGGCCGCGAGCGGCCG
AGGGCATGCTCGGCGCGATGTGCGCCGGTGACGTGGGAACCGTTTAG

Upstream 100 bases:

>100_bases
CTAACTCGCGAGGGTACGCAAACTGCTGCGAAACCGCGAGACACGCACCCTCGCGCCAAAGAACGCAGGGGGAGTTCACG
GCACGTTCAGGTGCCGGTCG

Downstream 100 bases:

>100_bases
CCGCCGACGCGGAGGGGCACCCGCAATCAGCGGGACAGTCAATATGACCTTGCCCGACCGACCGAAGGAGCCGACGTGGA
TACCAGCACCATCGTCTGGA

Product: group 1 glycosyl transferase

Products: NA

Alternate protein names: Alpha-D-mannose-alpha-(1-6)-phosphatidylmyo-inositol-mannosyltransferase; Guanosine diphosphomannose-phosphatidyl-inositol alpha-mannosyltransferase; Phosphatidylinositol alpha-mannosyltransferase; PI alpha-mannosyltransferase [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MRGRATHRSDRFPRGMRVVQVANFYGPRSGGLRTAVDRLGAEYCAAGHEVYLVVPGHRTEHQRLATGVTRITLPARLIPF
TGGYRAVLPGPVTALLHELQPDAIEVSDRLTLRSLGGWGRRHGVATVMISHERLDRLVGQVVPGRVARAVADIANRRTAS
NYDTVVCTTAFARREFDRIDATNVVTVPLGVDLDQFHPRRRSDQMRRRWAAPDQTLLVHCGRLSVEKHAHRSIDAVAALR
HSGVDARLVVVGEGPLRQRLERQATGLPVDFTGYIGCRDTVAGILASADVALAPGPHETFGLAALEALACGTPAVVSRTS
ALAEILTADSGAAADNDPQAIADAVGRVIRVPETVRRINARRRAEQFTWPRAAEGMLGAMCAGDVGTV

Sequences:

>Translated_388_residues
MRGRATHRSDRFPRGMRVVQVANFYGPRSGGLRTAVDRLGAEYCAAGHEVYLVVPGHRTEHQRLATGVTRITLPARLIPF
TGGYRAVLPGPVTALLHELQPDAIEVSDRLTLRSLGGWGRRHGVATVMISHERLDRLVGQVVPGRVARAVADIANRRTAS
NYDTVVCTTAFARREFDRIDATNVVTVPLGVDLDQFHPRRRSDQMRRRWAAPDQTLLVHCGRLSVEKHAHRSIDAVAALR
HSGVDARLVVVGEGPLRQRLERQATGLPVDFTGYIGCRDTVAGILASADVALAPGPHETFGLAALEALACGTPAVVSRTS
ALAEILTADSGAAADNDPQAIADAVGRVIRVPETVRRINARRRAEQFTWPRAAEGMLGAMCAGDVGTV
>Mature_388_residues
MRGRATHRSDRFPRGMRVVQVANFYGPRSGGLRTAVDRLGAEYCAAGHEVYLVVPGHRTEHQRLATGVTRITLPARLIPF
TGGYRAVLPGPVTALLHELQPDAIEVSDRLTLRSLGGWGRRHGVATVMISHERLDRLVGQVVPGRVARAVADIANRRTAS
NYDTVVCTTAFARREFDRIDATNVVTVPLGVDLDQFHPRRRSDQMRRRWAAPDQTLLVHCGRLSVEKHAHRSIDAVAALR
HSGVDARLVVVGEGPLRQRLERQATGLPVDFTGYIGCRDTVAGILASADVALAPGPHETFGLAALEALACGTPAVVSRTS
ALAEILTADSGAAADNDPQAIADAVGRVIRVPETVRRINARRRAEQFTWPRAAEGMLGAMCAGDVGTV

Specific function: Catalyzes the addition of a mannose residue from GDP-D- mannose to the position 6 of the alpha-1,6-linked mannose residue of the triacyl phosphatidylinositol dimannoside (Ac3PIM2) to generate triacyl phosphatidylinositol trimannoside (Ac3PIM3) [H]

COG id: COG0438

COG function: function code M; Glycosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296 [H]

Pfam domain/function: PF00534 Glycos_transf_1 [H]

EC number: =2.4.1.57 [H]

Molecular weight: Translated: 41895; Mature: 41895

Theoretical pI: Translated: 10.49; Mature: 10.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGRATHRSDRFPRGMRVVQVANFYGPRSGGLRTAVDRLGAEYCAAGHEVYLVVPGHRTE
CCCCCCCCCCCCCCCCEEEEEHHHCCCCCCCHHHHHHHHCHHHHCCCCEEEEEECCCCCH
HQRLATGVTRITLPARLIPFTGGYRAVLPGPVTALLHELQPDAIEVSDRLTLRSLGGWGR
HHHHHHCHHEEEECCEEEECCCCCEEECCCHHHHHHHHCCCCCEECCCCHHHHHHCCCCH
RHGVATVMISHERLDRLVGQVVPGRVARAVADIANRRTASNYDTVVCTTAFARREFDRID
HCCEEEEEECHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHCC
ATNVVTVPLGVDLDQFHPRRRSDQMRRRWAAPDQTLLVHCGRLSVEKHAHRSIDAVAALR
CCCEEEEECCCCHHHCCCCCHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHH
HSGVDARLVVVGEGPLRQRLERQATGLPVDFTGYIGCRDTVAGILASADVALAPGPHETF
HCCCCEEEEEECCCHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHCCCEEECCCCCHHH
GLAALEALACGTPAVVSRTSALAEILTADSGAAADNDPQAIADAVGRVIRVPETVRRINA
HHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHH
RRRAEQFTWPRAAEGMLGAMCAGDVGTV
HHHHHHCCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRGRATHRSDRFPRGMRVVQVANFYGPRSGGLRTAVDRLGAEYCAAGHEVYLVVPGHRTE
CCCCCCCCCCCCCCCCEEEEEHHHCCCCCCCHHHHHHHHCHHHHCCCCEEEEEECCCCCH
HQRLATGVTRITLPARLIPFTGGYRAVLPGPVTALLHELQPDAIEVSDRLTLRSLGGWGR
HHHHHHCHHEEEECCEEEECCCCCEEECCCHHHHHHHHCCCCCEECCCCHHHHHHCCCCH
RHGVATVMISHERLDRLVGQVVPGRVARAVADIANRRTASNYDTVVCTTAFARREFDRID
HCCEEEEEECHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHCC
ATNVVTVPLGVDLDQFHPRRRSDQMRRRWAAPDQTLLVHCGRLSVEKHAHRSIDAVAALR
CCCEEEEECCCCHHHCCCCCHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHH
HSGVDARLVVVGEGPLRQRLERQATGLPVDFTGYIGCRDTVAGILASADVALAPGPHETF
HCCCCEEEEEECCCHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHCCCEEECCCCCHHH
GLAALEALACGTPAVVSRTSALAEILTADSGAAADNDPQAIADAVGRVIRVPETVRRINA
HHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHH
RRRAEQFTWPRAAEGMLGAMCAGDVGTV
HHHHHHCCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10531227 [H]