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The map label for this gene is dapA [H]

Identifier: 108799581

GI number: 108799581

Start: 2772035

End: 2772985

Strand: Reverse

Name: dapA [H]

Synonym: Mmcs_2614

Alternate gene names: 108799581

Gene position: 2772985-2772035 (Counterclockwise)

Preceding gene: 108799582

Following gene: 108799580

Centisome position: 48.6

GC content: 64.35

Gene sequence:

>951_bases
ATGACAGCCCGTCGAGATCCGCACAGCATCCGCGGATCCATCACTCCGTTGATGACGCCGTTCACCGACGACGGCGCAGT
CGATCATCGGAGCCTTGCCAATCTCGTCAACTGGCAACTGGCCAGCGGCAGCCACGGTATCTCGATCGGCGGCTCCACCG
GAGAACCGGGCGCGCAGTCGGTCGCGGAGCGTCTCGCTGCGATCGCGACGGTCATGAAATCTGTGTCAGGCCGGGCGCCG
GTGGTGGCCGGAACCGGCACGGCCCAGCTCGACGAGACCATCGAACTGACCGGTCGGGCTGCGGAACTCGGGATCGATGC
GGCACTGGTCATCACGCCGTACTATGCCCGGCCGACTCAGGAGGCGCTGTACCGCTGGTACAAGACGGTTGCCGAGGAGT
ATCCCGATCTGCCGATCCTGGCCTACAACGTTCCGGTACGGACCGCCGTCGATCTCGCGCCGGAGACCATCGCCCGCCTC
TACCGTGACGTCGAGAACTTCGTCGGCGTCAAAGAGACGACCAAGGACTTCGAGCACTTCTCCCGGGTGATGCACCTGTG
CGGCCCCGACATCATCGTCTGGTCGGGGATAGAGCTGCTGTGCTTGCCGTTGCTCGCACTCGGTGGCACCGGGTTCCTCA
GCGCGACAGCCAATATCGCTCCCGCTGCTCATGCACGGATGTACGAGTTGTGGATCGCCGGTGCGCACGAGGAGGCCCGG
GCCATCCATTATGGCCTGCATCCCCTGGTGGATCTGCTGTTCGTCGAGACCAACCCGGCGCCGGGCAAGTGGCTGCTCAA
GGATCTCGGCCTGATTGCCTCTGACCATGTTCGCCCGCCATTGATCACGCCGACGCCGGGCGCACTGGAGAGAATCGCCG
TGTTGCGGCGTGCTGGCGAGAAGTTCCTCACGCCAGTAGGCGATTTCGCACTGGAAGGAGCTTTCGCGTGA

Upstream 100 bases:

>100_bases
CACTCGAAGGTCTCTATCCCATGAACGACTCGGCACGCGCCGACTACGAGCAGTCTCGGCACGGCCGCCACGCCGACACC
ACCCCGAAAGGTTCGACACC

Downstream 100 bases:

>100_bases
CCGCGAACCGTCGGCCCGAGGGTGTACCGCAGCGCATCCAGCACTTCATCGGCGGGAAGTTGGTCGACAGCCTTGCCGAC
ACGTGGTTCGACGTCATCGA

Product: dihydrodipicolinate synthase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MTARRDPHSIRGSITPLMTPFTDDGAVDHRSLANLVNWQLASGSHGISIGGSTGEPGAQSVAERLAAIATVMKSVSGRAP
VVAGTGTAQLDETIELTGRAAELGIDAALVITPYYARPTQEALYRWYKTVAEEYPDLPILAYNVPVRTAVDLAPETIARL
YRDVENFVGVKETTKDFEHFSRVMHLCGPDIIVWSGIELLCLPLLALGGTGFLSATANIAPAAHARMYELWIAGAHEEAR
AIHYGLHPLVDLLFVETNPAPGKWLLKDLGLIASDHVRPPLITPTPGALERIAVLRRAGEKFLTPVGDFALEGAFA

Sequences:

>Translated_316_residues
MTARRDPHSIRGSITPLMTPFTDDGAVDHRSLANLVNWQLASGSHGISIGGSTGEPGAQSVAERLAAIATVMKSVSGRAP
VVAGTGTAQLDETIELTGRAAELGIDAALVITPYYARPTQEALYRWYKTVAEEYPDLPILAYNVPVRTAVDLAPETIARL
YRDVENFVGVKETTKDFEHFSRVMHLCGPDIIVWSGIELLCLPLLALGGTGFLSATANIAPAAHARMYELWIAGAHEEAR
AIHYGLHPLVDLLFVETNPAPGKWLLKDLGLIASDHVRPPLITPTPGALERIAVLRRAGEKFLTPVGDFALEGAFA
>Mature_315_residues
TARRDPHSIRGSITPLMTPFTDDGAVDHRSLANLVNWQLASGSHGISIGGSTGEPGAQSVAERLAAIATVMKSVSGRAPV
VAGTGTAQLDETIELTGRAAELGIDAALVITPYYARPTQEALYRWYKTVAEEYPDLPILAYNVPVRTAVDLAPETIARLY
RDVENFVGVKETTKDFEHFSRVMHLCGPDIIVWSGIELLCLPLLALGGTGFLSATANIAPAAHARMYELWIAGAHEEARA
IHYGLHPLVDLLFVETNPAPGKWLLKDLGLIASDHVRPPLITPTPGALERIAVLRRAGEKFLTPVGDFALEGAFA

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=240, Percent_Identity=29.5833333333333, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI13540533, Length=251, Percent_Identity=25.4980079681275, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1788823, Length=289, Percent_Identity=40.8304498269896, Blast_Score=211, Evalue=4e-56,
Organism=Escherichia coli, GI87082415, Length=292, Percent_Identity=29.4520547945205, Blast_Score=130, Evalue=8e-32,
Organism=Escherichia coli, GI1786463, Length=276, Percent_Identity=31.5217391304348, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1789620, Length=274, Percent_Identity=25.9124087591241, Blast_Score=104, Evalue=7e-24,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 33958; Mature: 33827

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: PS00666 DHDPS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTARRDPHSIRGSITPLMTPFTDDGAVDHRSLANLVNWQLASGSHGISIGGSTGEPGAQS
CCCCCCCHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHEECCCCCCEEECCCCCCCHHHH
VAERLAAIATVMKSVSGRAPVVAGTGTAQLDETIELTGRAAELGIDAALVITPYYARPTQ
HHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHCCCHHHHCCCEEEEEECCCCCCHH
EALYRWYKTVAEEYPDLPILAYNVPVRTAVDLAPETIARLYRDVENFVGVKETTKDFEHF
HHHHHHHHHHHHHCCCCCEEEECCCHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHH
SRVMHLCGPDIIVWSGIELLCLPLLALGGTGFLSATANIAPAAHARMYELWIAGAHEEAR
HHHHHHHCCCEEEECCHHHHHHHHHHHCCCCHHHCCCCCCCHHHHHHHHHHEECCCHHHH
AIHYGLHPLVDLLFVETNPAPGKWLLKDLGLIASDHVRPPLITPTPGALERIAVLRRAGE
HHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCH
KFLTPVGDFALEGAFA
HHCCCHHHHHHCCCCC
>Mature Secondary Structure 
TARRDPHSIRGSITPLMTPFTDDGAVDHRSLANLVNWQLASGSHGISIGGSTGEPGAQS
CCCCCCHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHEECCCCCCEEECCCCCCCHHHH
VAERLAAIATVMKSVSGRAPVVAGTGTAQLDETIELTGRAAELGIDAALVITPYYARPTQ
HHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHCCCHHHHCCCEEEEEECCCCCCHH
EALYRWYKTVAEEYPDLPILAYNVPVRTAVDLAPETIARLYRDVENFVGVKETTKDFEHF
HHHHHHHHHHHHHCCCCCEEEECCCHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHH
SRVMHLCGPDIIVWSGIELLCLPLLALGGTGFLSATANIAPAAHARMYELWIAGAHEEAR
HHHHHHHCCCEEEECCHHHHHHHHHHHCCCCHHHCCCCCCCHHHHHHHHHHEECCCHHHH
AIHYGLHPLVDLLFVETNPAPGKWLLKDLGLIASDHVRPPLITPTPGALERIAVLRRAGE
HHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCH
KFLTPVGDFALEGAFA
HHCCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA