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The map label for this gene is qor [H]

Identifier: 108799394

GI number: 108799394

Start: 2576954

End: 2577937

Strand: Reverse

Name: qor [H]

Synonym: Mmcs_2427

Alternate gene names: 108799394

Gene position: 2577937-2576954 (Counterclockwise)

Preceding gene: 108799396

Following gene: 108799393

Centisome position: 45.18

GC content: 70.12

Gene sequence:

>984_bases
ATGGTTCCCATGTACGCGATCGAAGTCTCCGAAACCGGCGGTCCCGAAGTCCTCACCCACGTCGAGAAGGAACCCCCTTC
ACCCGGCCCGGGCCAGGTGCTGATCAAGGCCGAGGCGATCGGCGTCAACTTCATCGACACCTACTTCCGGTCGGGCCTGT
ATCCGCGGGAGGTGCCGTTCGTCGTCGGCACCGAGGTCTGCGGCACGATCGAGGCCGTCGGCGACGACGTGGCGGCGCTT
CAGGTGGGCGACCGGGTGGTGACCGACAAGGCCGTCGGCGCCTATGCCGAATACACCGTGGCGCCTGCGGATTTCGTGGC
CTACGTGCCCGACGGGGTGGCCCCCGCGGTCGCCGCCTCCTCGCTGCTCAAGGGAATGACCGCCCACTACCTGATCAAGT
CCACGTACCCGGTCCAGCAGGGCGACACGGTGCTGCTGCACGCCGGGGCCGGCGGCGTCGGGCTGATCCTCACGCAGTGG
GCGACGAGCCTGACGGCCAAGGTCATCACGACCGTCTCCACACCGCAGAAGGCCGAACTCTCGCGCCAGGCCGGGGCGAT
CGAGGTGCTCGACTACCCGCACGACCCGCAGGAGTTCGGCGCCCGCATCCGCGATCTCACCGGCGGCAACGGGGTGGCCG
CCGTCTACGACGGCGTGGGCGCGGCGACTTTCGACGCCAGCCTGGCCAGCCTCGCGGTGCGCGGCACCCTCGTCCTGTTC
GGCGGCGCCAGCGGCCCGGTCCCCCCGGTCGACCCGCAGCGGCTCAACTCGGCGGGGTCGGTGTACCTGACCAGGCCCAG
CCTGGTGCACTACACCCGCACCCCCGACGAATTCTCTTGGCGGGCAGGCGAAGTGCTCGACGCGATCGCCAAGGGGGCCA
TCACGGTGACGGTCAGCGAGCACTATCCGCTGCAGGAGGCCGAACGCGCGCACCGCGATCTGCAGGGGCGCAAGACGGTC
GGTTCCGTGGTCCTGGTCCCGTGA

Upstream 100 bases:

>100_bases
CGTCACCCTCGGGAAGGGCAGGGCAGCCGGCCAGCACGATCCGCGGATGGAACAGGTCGGGACGCGCGAGCCTCACCTGG
GTCATGCTAGGCGGTGGATG

Downstream 100 bases:

>100_bases
GGTGGCGCAGGATCTTGTGGTCTCGACGACGCTGGTGATCGCCGGATCCGAACTGAGCGAACGCTTCTCGAGGTCCTCGG
GTCCCGGCGGGCAGGGCGTC

Product: zinc-binding alcohol dehydrogenase

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MVPMYAIEVSETGGPEVLTHVEKEPPSPGPGQVLIKAEAIGVNFIDTYFRSGLYPREVPFVVGTEVCGTIEAVGDDVAAL
QVGDRVVTDKAVGAYAEYTVAPADFVAYVPDGVAPAVAASSLLKGMTAHYLIKSTYPVQQGDTVLLHAGAGGVGLILTQW
ATSLTAKVITTVSTPQKAELSRQAGAIEVLDYPHDPQEFGARIRDLTGGNGVAAVYDGVGAATFDASLASLAVRGTLVLF
GGASGPVPPVDPQRLNSAGSVYLTRPSLVHYTRTPDEFSWRAGEVLDAIAKGAITVTVSEHYPLQEAERAHRDLQGRKTV
GSVVLVP

Sequences:

>Translated_327_residues
MVPMYAIEVSETGGPEVLTHVEKEPPSPGPGQVLIKAEAIGVNFIDTYFRSGLYPREVPFVVGTEVCGTIEAVGDDVAAL
QVGDRVVTDKAVGAYAEYTVAPADFVAYVPDGVAPAVAASSLLKGMTAHYLIKSTYPVQQGDTVLLHAGAGGVGLILTQW
ATSLTAKVITTVSTPQKAELSRQAGAIEVLDYPHDPQEFGARIRDLTGGNGVAAVYDGVGAATFDASLASLAVRGTLVLF
GGASGPVPPVDPQRLNSAGSVYLTRPSLVHYTRTPDEFSWRAGEVLDAIAKGAITVTVSEHYPLQEAERAHRDLQGRKTV
GSVVLVP
>Mature_327_residues
MVPMYAIEVSETGGPEVLTHVEKEPPSPGPGQVLIKAEAIGVNFIDTYFRSGLYPREVPFVVGTEVCGTIEAVGDDVAAL
QVGDRVVTDKAVGAYAEYTVAPADFVAYVPDGVAPAVAASSLLKGMTAHYLIKSTYPVQQGDTVLLHAGAGGVGLILTQW
ATSLTAKVITTVSTPQKAELSRQAGAIEVLDYPHDPQEFGARIRDLTGGNGVAAVYDGVGAATFDASLASLAVRGTLVLF
GGASGPVPPVDPQRLNSAGSVYLTRPSLVHYTRTPDEFSWRAGEVLDAIAKGAITVTVSEHYPLQEAERAHRDLQGRKTV
GSVVLVP

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=328, Percent_Identity=30.7926829268293, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI13236495, Length=328, Percent_Identity=30.7926829268293, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI194239676, Length=328, Percent_Identity=28.6585365853659, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI22538446, Length=330, Percent_Identity=27.2727272727273, Blast_Score=108, Evalue=9e-24,
Organism=Homo sapiens, GI22538444, Length=330, Percent_Identity=27.2727272727273, Blast_Score=108, Evalue=9e-24,
Organism=Homo sapiens, GI24308257, Length=348, Percent_Identity=26.1494252873563, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI28557745, Length=228, Percent_Identity=32.4561403508772, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI18379349, Length=313, Percent_Identity=26.1980830670927, Blast_Score=89, Evalue=6e-18,
Organism=Escherichia coli, GI1790485, Length=325, Percent_Identity=44.6153846153846, Blast_Score=260, Evalue=1e-70,
Organism=Escherichia coli, GI1787863, Length=212, Percent_Identity=26.8867924528302, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17507255, Length=240, Percent_Identity=29.5833333333333, Blast_Score=98, Evalue=7e-21,
Organism=Saccharomyces cerevisiae, GI6319520, Length=324, Percent_Identity=34.8765432098765, Blast_Score=191, Evalue=1e-49,
Organism=Saccharomyces cerevisiae, GI6323961, Length=267, Percent_Identity=25.4681647940075, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6324486, Length=247, Percent_Identity=25.5060728744939, Blast_Score=63, Evalue=5e-11,
Organism=Drosophila melanogaster, GI45550423, Length=318, Percent_Identity=26.7295597484277, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 34193; Mature: 34193

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVPMYAIEVSETGGPEVLTHVEKEPPSPGPGQVLIKAEAIGVNFIDTYFRSGLYPREVPF
CCCEEEEEECCCCCCHHHHHHHCCCCCCCCCCEEEEEEECCCHHHHHHHHCCCCCCCCCE
VVGTEVCGTIEAVGDDVAALQVGDRVVTDKAVGAYAEYTVAPADFVAYVPDGVAPAVAAS
EECCHHHHHHHHHCCCEEEEEECCEEEEHHHHCCHHHEEECCHHHEEECCCCCHHHHHHH
SLLKGMTAHYLIKSTYPVQQGDTVLLHAGAGGVGLILTQWATSLTAKVITTVSTPQKAEL
HHHHHHHHHEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHEEECCCCCHHHH
SRQAGAIEVLDYPHDPQEFGARIRDLTGGNGVAAVYDGVGAATFDASLASLAVRGTLVLF
HHHCCCEEEECCCCCHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHEEEEEEEEE
GGASGPVPPVDPQRLNSAGSVYLTRPSLVHYTRTPDEFSWRAGEVLDAIAKGAITVTVSE
ECCCCCCCCCCHHHCCCCCCEEEECCCEEEEECCCCCCCCCHHHHHHHHHCCEEEEEECC
HYPLQEAERAHRDLQGRKTVGSVVLVP
CCCHHHHHHHHHHCCCCCCCCCEEEEC
>Mature Secondary Structure
MVPMYAIEVSETGGPEVLTHVEKEPPSPGPGQVLIKAEAIGVNFIDTYFRSGLYPREVPF
CCCEEEEEECCCCCCHHHHHHHCCCCCCCCCCEEEEEEECCCHHHHHHHHCCCCCCCCCE
VVGTEVCGTIEAVGDDVAALQVGDRVVTDKAVGAYAEYTVAPADFVAYVPDGVAPAVAAS
EECCHHHHHHHHHCCCEEEEEECCEEEEHHHHCCHHHEEECCHHHEEECCCCCHHHHHHH
SLLKGMTAHYLIKSTYPVQQGDTVLLHAGAGGVGLILTQWATSLTAKVITTVSTPQKAEL
HHHHHHHHHEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHEEECCCCCHHHH
SRQAGAIEVLDYPHDPQEFGARIRDLTGGNGVAAVYDGVGAATFDASLASLAVRGTLVLF
HHHCCCEEEECCCCCHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHEEEEEEEEE
GGASGPVPPVDPQRLNSAGSVYLTRPSLVHYTRTPDEFSWRAGEVLDAIAKGAITVTVSE
ECCCCCCCCCCHHHCCCCCCEEEECCCEEEEECCCCCCCCCHHHHHHHHHCCEEEEEECC
HYPLQEAERAHRDLQGRKTVGSVVLVP
CCCHHHHHHHHHHCCCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]