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The map label for this gene is hypA [H]

Identifier: 108799113

GI number: 108799113

Start: 2290089

End: 2290418

Strand: Reverse

Name: hypA [H]

Synonym: Mmcs_2146

Alternate gene names: 108799113

Gene position: 2290418-2290089 (Counterclockwise)

Preceding gene: 108799116

Following gene: 108799112

Centisome position: 40.14

GC content: 70.61

Gene sequence:

>330_bases
ATGCACGAGATGGCGATCACCCAGAGCGTTGTCGACGCGGTCTGTGACCACGCCGCCGGCCGACGCGTGCACAGCGTCCG
GCTCGAGGTGGGCGCACTGTGCGCCGTGGTGCCCGATGCGATGCGGTTCTGCTTCGAGCTGGCCACCGAGGGCACCGCCG
CCGACGGCGCCCGCCTCGACCTCGATGTGCGGCCGGGACTCGCGCGCTGCCGCACCTGTGACACCGACTTCGAACTGACC
GACCTGATCCTGCTGTGCCCGTGCGGCAGCGCCGACGTGGAAGTGCGCGCCGGCCGCGACCTGCGGATCCTCTCGATGGA
AGTGAGCTGA

Upstream 100 bases:

>100_bases
GGACACGCCGATGGCCACCACGGCGATCGGTGATTCCACCCGCCGGGCCCGCACACCGGCCTATCGTGAGGGCACCGCCC
CCGTCGAGGACGGCACACCG

Downstream 100 bases:

>100_bases
CCATGTGCGCAACCTGTGGCTGCGGCGGCGACGACGCGGTGATCACCCTGGGCCACGCCCACCCGCACCAGCACGCCCAC
CCGCACCAGCACGCCCATGA

Product: hydrogenase nickel insertion protein HypA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 109; Mature: 109

Protein sequence:

>109_residues
MHEMAITQSVVDAVCDHAAGRRVHSVRLEVGALCAVVPDAMRFCFELATEGTAADGARLDLDVRPGLARCRTCDTDFELT
DLILLCPCGSADVEVRAGRDLRILSMEVS

Sequences:

>Translated_109_residues
MHEMAITQSVVDAVCDHAAGRRVHSVRLEVGALCAVVPDAMRFCFELATEGTAADGARLDLDVRPGLARCRTCDTDFELT
DLILLCPCGSADVEVRAGRDLRILSMEVS
>Mature_109_residues
MHEMAITQSVVDAVCDHAAGRRVHSVRLEVGALCAVVPDAMRFCFELATEGTAADGARLDLDVRPGLARCRTCDTDFELT
DLILLCPCGSADVEVRAGRDLRILSMEVS

Specific function: Probably plays a role in an hydrogenase nickel cofactor insertion step [H]

COG id: COG0375

COG function: function code R; Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypA/hybF family [H]

Homologues:

Organism=Escherichia coli, GI1789365, Length=112, Percent_Identity=35.7142857142857, Blast_Score=62, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000688
- InterPro:   IPR020538 [H]

Pfam domain/function: PF01155 HypA [H]

EC number: NA

Molecular weight: Translated: 11749; Mature: 11749

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: PS01249 HYPA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

6.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
10.1 %Cys+Met (Translated Protein)
6.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
10.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHEMAITQSVVDAVCDHAAGRRVHSVRLEVGALCAVVPDAMRFCFELATEGTAADGARLD
CCCHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEE
LDVRPGLARCRTCDTDFELTDLILLCPCGSADVEVRAGRDLRILSMEVS
EECCCCCHHHCCCCCCCCCCCEEEECCCCCCCEEEECCCCEEEEEEECC
>Mature Secondary Structure
MHEMAITQSVVDAVCDHAAGRRVHSVRLEVGALCAVVPDAMRFCFELATEGTAADGARLD
CCCHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEE
LDVRPGLARCRTCDTDFELTDLILLCPCGSADVEVRAGRDLRILSMEVS
EECCCCCHHHCCCCCCCCCCCEEEECCCCCCCEEEECCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA