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The map label for this gene is iap [H]

Identifier: 108798418

GI number: 108798418

Start: 1574527

End: 1575297

Strand: Reverse

Name: iap [H]

Synonym: Mmcs_1447

Alternate gene names: 108798418

Gene position: 1575297-1574527 (Counterclockwise)

Preceding gene: 108798419

Following gene: 108798411

Centisome position: 27.61

GC content: 66.02

Gene sequence:

>771_bases
ATGCAATCACTCCCCCGCAACGCGGGCGCGGCCACTGTCTGCGCCGACCGTCGGGCAAGGGCCGTGCATGCAGAGAGCAC
AGGCCGGCGGGTAGCCGCCGGTGTCATCGCCCTCGTCTCGCTGCTGATCACCTGCGCGCCCATCGCGTCGGCGCAACCTG
CCGCGGGCCCGTGGGACCCTCTGCTTCCCAAGGTGCCCAGTGCGGGCGCGCCCGGCGATCCGGTCGCTATCGCGAATGCC
TCGTTGCAAGCAACGGCCATGGCGACGCAGACGGCGATGACTCTGGGGCGCAGCTTCTTGAGCAGCCTGGGTATTGTCAG
TCCCGCCGCCACTCCTGAAGCGAGCATTCGCGGCGGCAGGATCAATGGCACCCAAGCAATCGAATACGTCATACGGCGAG
CCGGCACTCAGATCGGAGTGCCCTACTCTTGGGGCGGCGGCAGTCTCACCGGTCCGAGCCGCGGGGTCGATCAGGGTGCG
AACACGGTGGGCTTCGACTGTTCGGGCCTGACGCGGTTCGCCTTCGCCGGCGTGGGGGTGCTACTTCCGCGGTGGTCTGG
AGATCAATACAACGCCGGTCGCAAGATTCCTCCCGCACAGGCCAAGCGCGGAGATCTGCTGTTCTGGGGACCAGGCGGAA
GTCAGCACGAAGCGATCTACCTGGGCGGCGGTCAGATGCTCGAAGCGCAGCAGACGGGCGTGCCGATCAAAATCTCGCCC
GTACGGATGTCAGGGATGACACCGTATGTTGTCCGCATCATCGAAACCTGA

Upstream 100 bases:

>100_bases
GTAGCAGCTACGTATTTCGGTGTTGTGCCGATGCGTAGGCGATCTGAGGCCGATGCGGGCGTGTATGTCCGTCACTGCAG
CGGCACACCGAGGAGAAGCC

Downstream 100 bases:

>100_bases
ACGCGCAGTGGCGAAGAGCCACTTTGTGGCCTCGGCGCACGCATCGCACCACCGTCGCGATGGCGCCGCTGTCCTCAGCC
CACCAAACAGTAACCGAGGC

Product: NLP/P60

Products: NA

Alternate protein names: Invasion-associated protein [H]

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MQSLPRNAGAATVCADRRARAVHAESTGRRVAAGVIALVSLLITCAPIASAQPAAGPWDPLLPKVPSAGAPGDPVAIANA
SLQATAMATQTAMTLGRSFLSSLGIVSPAATPEASIRGGRINGTQAIEYVIRRAGTQIGVPYSWGGGSLTGPSRGVDQGA
NTVGFDCSGLTRFAFAGVGVLLPRWSGDQYNAGRKIPPAQAKRGDLLFWGPGGSQHEAIYLGGGQMLEAQQTGVPIKISP
VRMSGMTPYVVRIIET

Sequences:

>Translated_256_residues
MQSLPRNAGAATVCADRRARAVHAESTGRRVAAGVIALVSLLITCAPIASAQPAAGPWDPLLPKVPSAGAPGDPVAIANA
SLQATAMATQTAMTLGRSFLSSLGIVSPAATPEASIRGGRINGTQAIEYVIRRAGTQIGVPYSWGGGSLTGPSRGVDQGA
NTVGFDCSGLTRFAFAGVGVLLPRWSGDQYNAGRKIPPAQAKRGDLLFWGPGGSQHEAIYLGGGQMLEAQQTGVPIKISP
VRMSGMTPYVVRIIET
>Mature_256_residues
MQSLPRNAGAATVCADRRARAVHAESTGRRVAAGVIALVSLLITCAPIASAQPAAGPWDPLLPKVPSAGAPGDPVAIANA
SLQATAMATQTAMTLGRSFLSSLGIVSPAATPEASIRGGRINGTQAIEYVIRRAGTQIGVPYSWGGGSLTGPSRGVDQGA
NTVGFDCSGLTRFAFAGVGVLLPRWSGDQYNAGRKIPPAQAKRGDLLFWGPGGSQHEAIYLGGGQMLEAQQTGVPIKISP
VRMSGMTPYVVRIIET

Specific function: This major extracellular protein may be involved in the invasion of non-professional phagocytic cells by Listeria [H]

COG id: COG0791

COG function: function code M; Cell wall-associated hydrolases (invasion-associated proteins)

Gene ontology:

Cell location: Attached To The Membrane By A Lipid Anchor [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 LysM repeats [H]

Homologues:

Organism=Escherichia coli, GI1786421, Length=118, Percent_Identity=36.4406779661017, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787944, Length=123, Percent_Identity=31.7073170731707, Blast_Score=68, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000064
- InterPro:   IPR018392
- InterPro:   IPR002482
- InterPro:   IPR003646
- InterPro:   IPR013247 [H]

Pfam domain/function: PF01476 LysM; PF00877 NLPC_P60; PF08239 SH3_3 [H]

EC number: NA

Molecular weight: Translated: 26242; Mature: 26242

Theoretical pI: Translated: 10.49; Mature: 10.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSLPRNAGAATVCADRRARAVHAESTGRRVAAGVIALVSLLITCAPIASAQPAAGPWDP
CCCCCCCCCCEEEEHHCHHHEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
LLPKVPSAGAPGDPVAIANASLQATAMATQTAMTLGRSFLSSLGIVSPAATPEASIRGGR
CCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
INGTQAIEYVIRRAGTQIGVPYSWGGGSLTGPSRGVDQGANTVGFDCSGLTRFAFAGVGV
CCHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCE
LLPRWSGDQYNAGRKIPPAQAKRGDLLFWGPGGSQHEAIYLGGGQMLEAQQTGVPIKISP
EEECCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCEEEECCCCEEEHHHCCCCEEEEC
VRMSGMTPYVVRIIET
EEECCCCCEEEEEECC
>Mature Secondary Structure
MQSLPRNAGAATVCADRRARAVHAESTGRRVAAGVIALVSLLITCAPIASAQPAAGPWDP
CCCCCCCCCCEEEEHHCHHHEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
LLPKVPSAGAPGDPVAIANASLQATAMATQTAMTLGRSFLSSLGIVSPAATPEASIRGGR
CCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
INGTQAIEYVIRRAGTQIGVPYSWGGGSLTGPSRGVDQGANTVGFDCSGLTRFAFAGVGV
CCHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCE
LLPRWSGDQYNAGRKIPPAQAKRGDLLFWGPGGSQHEAIYLGGGQMLEAQQTGVPIKISP
EEECCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCEEEECCCCEEEHHHCCCCEEEEC
VRMSGMTPYVVRIIET
EEECCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1514809; 1459966 [H]