| Definition | Mycobacterium sp. MCS chromosome, complete genome. |
|---|---|
| Accession | NC_008146 |
| Length | 5,705,448 |
Click here to switch to the map view.
The map label for this gene is icd [H]
Identifier: 108798180
GI number: 108798180
Start: 1307591
End: 1309843
Strand: Direct
Name: icd [H]
Synonym: Mmcs_1209
Alternate gene names: 108798180
Gene position: 1307591-1309843 (Clockwise)
Preceding gene: 108798176
Following gene: 108798182
Centisome position: 22.92
GC content: 64.54
Gene sequence:
>2253_bases ATGAGCGCCGAGCAGCCGACCATCATCTACACGCTGACCGACGAGGCGCCGCTGCTGGCGACATACGGCTTCCTGCCGAT CATCCGGACGTTCGCCGGAGCCGCGGGCATCAACGTCGAGACCAGTGACATCTCCGTGGCGGCGCGCATCCTCGGTGAAT TCAACGACCGTCTCCCCGAGGACCAGCGGGTGCCCGACAACCTGGCCAAGCTCGGCGAGCTGACGCAGGATCCGGCCACC AACATCATCAAGCTGCCCAACATCAGCGCCTCGGTCCCGCAGCTGCTGGCCGCGATCAAGGAGCTCAAGGCCAAGGGTTA CGACCTGCCGGACTACCCCGGCGACCCGAAGACCGACGAGGAGAAGGAGAACCGCGCTCGCTACGAGAAGGTGCTCGGCA GCGCGGTCAACCCCGTTCTGCGTCAAGGTAATTCGGATCGGCGCGCCCCCAAGGCGGTCAAGGAGTACGCCAAGAAACAT CCGCACAGCATGGGGGAGTGGTCGATGGCCTCTCGCACCCACGTGGCGACCATGCGGCACGGCGACTTCTACCACGGCGA GAAGTCGATGACGATCGACCGCGACCGCAAGGTCAAGATGGTGCTCGAGACCACCCCCAAAGACGGCGAGCCCGCAAGAA CTATCGTCCTCAAGCCCGAGGTCAAGCTCGACGAGGGCGACATCATCGACAGCATGTTCATGAGCAAGAAGGCGCTCTGC GAGTTCTACGAAGCGCAGATGCAGGACGCCTACGAGACCGGCGTGATGTTCTCGCTGCACGTCAAGGCGACCATGATGAA GGTCAGCCACCCGATCGTGTTCGGCCACGCGGTCAAGGTGTTCTACAAGGATGCGTTCGCCAAGCACCAGAAGCTGTTCG ACGAACTCGGCGTCAACGTCAACAACGGGATGTCCGACCTCTACAGCAAGATCGAGGCGCTGCCCGCCTCGCAGCGCGAG GAGATCATCAACGACATCCACGCCTGCCACGAGACCCGGCCCGAGCTGGCGATGGTCGACTCGGCGCGCGGCATCACCAA CTTCCACTCACCCAGCGACGTCATCGTGGACGCGTCGATGCCCGCGATGATCCGGTTGGGCGGCAAGATGTACGGCGCCG ACGGCCGCACCAAGGACACCAAGGCGGTCAACCCCGAGTCGACGTTCTCCCGGATGTACCAGGAGATGATCAACTGGTGT AAGACCAACGGCCAGTTCGACCCCACGACCATGGGCACCGTCCCCAACGTCGGCCTGATGGCGCAGAAGGCCGAGGAGTA CGGCAGCCACGACAAGACGTTCGAGATCCCCGAGGACGGCGTCGCGAACATCGTCGACATCGACACCGACGAGGTGCTGC TGACCCAAAACGTCGAAGAGGGCGACATCTGGCGGATGCCGATCGTCAAGGACGCCCCGATCCGCGACTGGGTGAAGTTG GCGGTCACCCGGGCCCGCGCCTCGGGGATGACGGCGGTGTTCTGGCTCGACACCGAGCGTCCGCACGAGGCCGAGCTGCG CAAGAAGGTCAAGGAGTACCTGAAGGACCACGACACCGAGGGCCTTCACATCCAGATCATGCCGCAGGTGTGGGCGATGC GGTACACGCTCGAGCGGGTGACGCGCGGCCAGGACACCATCGCGGTGACCGGCAACATCCTGCGCGACTACCTCACCGAC CTGTTCCCGATCCTGGAACTGGGCACCAGCGCCAAGATGCTGTCGATCGTCCCGCTGATGGCCGGTGGCGGCATGTACGA GACGGGTGCGGGCGGTTCGGCGCCCAAGCACGTCCACCAGCTGATCGAAGAGAACCACCTGCGGTGGGATTCGCTCGGCG AGTTCCTCGCGCTCGGCGCCTGCTTCGAGGATCTGGGCCGCAAGACCGACAACAAGCGGGCCGCGCTGCTCGGCAAGACG ATGGACGCCGCGATCGGCAAGCTGCTCGACAACGACAAGGGCCCGTCGCGCAAGACCGGTGAACTCGACAACCGGGGCAG CCAGTTCTACCTCGCGATGTACTGGGCGCAGGAACTCGCCGGGCAGACCGAGGACAAGGAGCTGGCCGAGCACTTCGCAC CCCTGGCCGAGGCGCTGGTCAAGAACGAGGAGACCATCGTAAAGGAGCTCGCGGCCGAACAGGGCAAGTCGGTCGACATC GGCGGCTACTACTACCCGGACAGCGAGAAGACCACGGCCGTGATGCGGCCGAGCAAGACCCTCAACGAGACGTTGGAGTC CGCCTCGGTGTAG
Upstream 100 bases:
>100_bases AGGCGGCCCGAACTGCAGGGAGCCGTTTCTGCGCGGGGGGCTGCCGGGTAGCGTCGTAGCCGACAATGCGGAGCTTCGAT CTGACGCCGGGAGACACCAA
Downstream 100 bases:
>100_bases TCGGCGGCTCTAGCCCGCCGGCGGGACGGCTCGGTGATCGGTCGAGCCGGCCACCCGGTCCACGAAGTCGACGATCAGCT TCGCGACGCGCTCGGGCGCC
Product: isocitrate dehydrogenase, NADP-dependent
Products: NA
Alternate protein names: IDH; Oxalosuccinate decarboxylase [H]
Number of amino acids: Translated: 750; Mature: 749
Protein sequence:
>750_residues MSAEQPTIIYTLTDEAPLLATYGFLPIIRTFAGAAGINVETSDISVAARILGEFNDRLPEDQRVPDNLAKLGELTQDPAT NIIKLPNISASVPQLLAAIKELKAKGYDLPDYPGDPKTDEEKENRARYEKVLGSAVNPVLRQGNSDRRAPKAVKEYAKKH PHSMGEWSMASRTHVATMRHGDFYHGEKSMTIDRDRKVKMVLETTPKDGEPARTIVLKPEVKLDEGDIIDSMFMSKKALC EFYEAQMQDAYETGVMFSLHVKATMMKVSHPIVFGHAVKVFYKDAFAKHQKLFDELGVNVNNGMSDLYSKIEALPASQRE EIINDIHACHETRPELAMVDSARGITNFHSPSDVIVDASMPAMIRLGGKMYGADGRTKDTKAVNPESTFSRMYQEMINWC KTNGQFDPTTMGTVPNVGLMAQKAEEYGSHDKTFEIPEDGVANIVDIDTDEVLLTQNVEEGDIWRMPIVKDAPIRDWVKL AVTRARASGMTAVFWLDTERPHEAELRKKVKEYLKDHDTEGLHIQIMPQVWAMRYTLERVTRGQDTIAVTGNILRDYLTD LFPILELGTSAKMLSIVPLMAGGGMYETGAGGSAPKHVHQLIEENHLRWDSLGEFLALGACFEDLGRKTDNKRAALLGKT MDAAIGKLLDNDKGPSRKTGELDNRGSQFYLAMYWAQELAGQTEDKELAEHFAPLAEALVKNEETIVKELAAEQGKSVDI GGYYYPDSEKTTAVMRPSKTLNETLESASV
Sequences:
>Translated_750_residues MSAEQPTIIYTLTDEAPLLATYGFLPIIRTFAGAAGINVETSDISVAARILGEFNDRLPEDQRVPDNLAKLGELTQDPAT NIIKLPNISASVPQLLAAIKELKAKGYDLPDYPGDPKTDEEKENRARYEKVLGSAVNPVLRQGNSDRRAPKAVKEYAKKH PHSMGEWSMASRTHVATMRHGDFYHGEKSMTIDRDRKVKMVLETTPKDGEPARTIVLKPEVKLDEGDIIDSMFMSKKALC EFYEAQMQDAYETGVMFSLHVKATMMKVSHPIVFGHAVKVFYKDAFAKHQKLFDELGVNVNNGMSDLYSKIEALPASQRE EIINDIHACHETRPELAMVDSARGITNFHSPSDVIVDASMPAMIRLGGKMYGADGRTKDTKAVNPESTFSRMYQEMINWC KTNGQFDPTTMGTVPNVGLMAQKAEEYGSHDKTFEIPEDGVANIVDIDTDEVLLTQNVEEGDIWRMPIVKDAPIRDWVKL AVTRARASGMTAVFWLDTERPHEAELRKKVKEYLKDHDTEGLHIQIMPQVWAMRYTLERVTRGQDTIAVTGNILRDYLTD LFPILELGTSAKMLSIVPLMAGGGMYETGAGGSAPKHVHQLIEENHLRWDSLGEFLALGACFEDLGRKTDNKRAALLGKT MDAAIGKLLDNDKGPSRKTGELDNRGSQFYLAMYWAQELAGQTEDKELAEHFAPLAEALVKNEETIVKELAAEQGKSVDI GGYYYPDSEKTTAVMRPSKTLNETLESASV >Mature_749_residues SAEQPTIIYTLTDEAPLLATYGFLPIIRTFAGAAGINVETSDISVAARILGEFNDRLPEDQRVPDNLAKLGELTQDPATN IIKLPNISASVPQLLAAIKELKAKGYDLPDYPGDPKTDEEKENRARYEKVLGSAVNPVLRQGNSDRRAPKAVKEYAKKHP HSMGEWSMASRTHVATMRHGDFYHGEKSMTIDRDRKVKMVLETTPKDGEPARTIVLKPEVKLDEGDIIDSMFMSKKALCE FYEAQMQDAYETGVMFSLHVKATMMKVSHPIVFGHAVKVFYKDAFAKHQKLFDELGVNVNNGMSDLYSKIEALPASQREE IINDIHACHETRPELAMVDSARGITNFHSPSDVIVDASMPAMIRLGGKMYGADGRTKDTKAVNPESTFSRMYQEMINWCK TNGQFDPTTMGTVPNVGLMAQKAEEYGSHDKTFEIPEDGVANIVDIDTDEVLLTQNVEEGDIWRMPIVKDAPIRDWVKLA VTRARASGMTAVFWLDTERPHEAELRKKVKEYLKDHDTEGLHIQIMPQVWAMRYTLERVTRGQDTIAVTGNILRDYLTDL FPILELGTSAKMLSIVPLMAGGGMYETGAGGSAPKHVHQLIEENHLRWDSLGEFLALGACFEDLGRKTDNKRAALLGKTM DAAIGKLLDNDKGPSRKTGELDNRGSQFYLAMYWAQELAGQTEDKELAEHFAPLAEALVKNEETIVKELAAEQGKSVDIG GYYYPDSEKTTAVMRPSKTLNETLESASV
Specific function: Unknown
COG id: COG2838
COG function: function code C; Monomeric isocitrate dehydrogenase
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Belongs to the monomeric-type IDH family [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001804 - InterPro: IPR004436 [H]
Pfam domain/function: PF03971 IDH [H]
EC number: =1.1.1.42 [H]
Molecular weight: Translated: 83438; Mature: 83307
Theoretical pI: Translated: 5.27; Mature: 5.27
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.5 %Cys (Translated Protein) 4.1 %Met (Translated Protein) 4.7 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 4.0 %Met (Mature Protein) 4.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSAEQPTIIYTLTDEAPLLATYGFLPIIRTFAGAAGINVETSDISVAARILGEFNDRLPE CCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCEECHHHHHHHHHHHHHHHCCCC DQRVPDNLAKLGELTQDPATNIIKLPNISASVPQLLAAIKELKAKGYDLPDYPGDPKTDE CCCCCHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCH EKENRARYEKVLGSAVNPVLRQGNSDRRAPKAVKEYAKKHPHSMGEWSMASRTHVATMRH HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEC GDFYHGEKSMTIDRDRKVKMVLETTPKDGEPARTIVLKPEVKLDEGDIIDSMFMSKKALC CCEECCCCCCEECCCCEEEEEEEECCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHH EFYEAQMQDAYETGVMFSLHVKATMMKVSHPIVFGHAVKVFYKDAFAKHQKLFDELGVNV HHHHHHHHHHHHCCCEEEEEHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCC NNGMSDLYSKIEALPASQREEIINDIHACHETRPELAMVDSARGITNFHSPSDVIVDASM CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEHHCCCCCCCCCCCCCEEEECCC PAMIRLGGKMYGADGRTKDTKAVNPESTFSRMYQEMINWCKTNGQFDPTTMGTVPNVGLM CHHHHCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHH AQKAEEYGSHDKTFEIPEDGVANIVDIDTDEVLLTQNVEEGDIWRMPIVKDAPIRDWVKL HHHHHHHCCCCCEEECCCCCCCCEEECCCCCEEEECCCCCCCEEECCCCCCCCHHHHHHH AVTRARASGMTAVFWLDTERPHEAELRKKVKEYLKDHDTEGLHIQIMPQVWAMRYTLERV HHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHH TRGQDTIAVTGNILRDYLTDLFPILELGTSAKMLSIVPLMAGGGMYETGAGGSAPKHVHQ HCCCCEEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEECCCCCCCHHHHHH LIEENHLRWDSLGEFLALGACFEDLGRKTDNKRAALLGKTMDAAIGKLLDNDKGPSRKTG HHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCC ELDNRGSQFYLAMYWAQELAGQTEDKELAEHFAPLAEALVKNEETIVKELAAEQGKSVDI CCCCCCCEEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEC GGYYYPDSEKTTAVMRPSKTLNETLESASV CCEECCCCCCCEEEECCCHHHHHHHHHCCC >Mature Secondary Structure SAEQPTIIYTLTDEAPLLATYGFLPIIRTFAGAAGINVETSDISVAARILGEFNDRLPE CCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCEECHHHHHHHHHHHHHHHCCCC DQRVPDNLAKLGELTQDPATNIIKLPNISASVPQLLAAIKELKAKGYDLPDYPGDPKTDE CCCCCHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCH EKENRARYEKVLGSAVNPVLRQGNSDRRAPKAVKEYAKKHPHSMGEWSMASRTHVATMRH HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEC GDFYHGEKSMTIDRDRKVKMVLETTPKDGEPARTIVLKPEVKLDEGDIIDSMFMSKKALC CCEECCCCCCEECCCCEEEEEEEECCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHH EFYEAQMQDAYETGVMFSLHVKATMMKVSHPIVFGHAVKVFYKDAFAKHQKLFDELGVNV HHHHHHHHHHHHCCCEEEEEHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCC NNGMSDLYSKIEALPASQREEIINDIHACHETRPELAMVDSARGITNFHSPSDVIVDASM CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEHHCCCCCCCCCCCCCEEEECCC PAMIRLGGKMYGADGRTKDTKAVNPESTFSRMYQEMINWCKTNGQFDPTTMGTVPNVGLM CHHHHCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHH AQKAEEYGSHDKTFEIPEDGVANIVDIDTDEVLLTQNVEEGDIWRMPIVKDAPIRDWVKL HHHHHHHCCCCCEEECCCCCCCCEEECCCCCEEEECCCCCCCEEECCCCCCCCHHHHHHH AVTRARASGMTAVFWLDTERPHEAELRKKVKEYLKDHDTEGLHIQIMPQVWAMRYTLERV HHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHH TRGQDTIAVTGNILRDYLTDLFPILELGTSAKMLSIVPLMAGGGMYETGAGGSAPKHVHQ HCCCCEEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEECCCCCCCHHHHHH LIEENHLRWDSLGEFLALGACFEDLGRKTDNKRAALLGKTMDAAIGKLLDNDKGPSRKTG HHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCC ELDNRGSQFYLAMYWAQELAGQTEDKELAEHFAPLAEALVKNEETIVKELAAEQGKSVDI CCCCCCCEEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEC GGYYYPDSEKTTAVMRPSKTLNETLESASV CCEECCCCCCCEEEECCCHHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 12005040; 4149369; 12467571 [H]