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The map label for this gene is yfjD [C]

Identifier: 108798071

GI number: 108798071

Start: 1197417

End: 1198694

Strand: Direct

Name: yfjD [C]

Synonym: Mmcs_1099

Alternate gene names: 108798071

Gene position: 1197417-1198694 (Clockwise)

Preceding gene: 108798070

Following gene: 108798072

Centisome position: 20.99

GC content: 68.23

Gene sequence:

>1278_bases
ATGAGCGACTACTGGCTGAACGTGGCCCTGGTATTCGCGCTCATACTGGTCAACGGGCTGCTGGCGGGAAGCGAAGCAGC
GTTCATCTCCCTGAGAGAGGGTCAGCTGCGCGAGCTGGAACATCGCGGCGGCCGACGGGATCTCACCGTCGTCGGGTTGG
CCCGAGAGCCGAACCGCTACCTCGCCACCATCCAACTGGGCATCACCCTGGCCGGATTCTTCGCCTCGGCCACCGCGGCG
GTCACCCTGGCGGAGCCGCTGGCCCCGCTGCTGGGCTTCCTGGGCGCCGGTGCACAGACGGCGGTCAGCATCGCGGTGGT
GACGGTGCTGGTGGCCGGTGTGACCCTCGTGTTCGGGGAGCTCGCGCCCAAGAGGCTGGCGATGCAGTACGCCCGGCGGT
GGGCACTCGTCGTGGCCTCACCGTTGAGTGCCATGTCGGCCGTCGCCGCACCGATCGCGTGGGTTCTCGGCAGGGCCACC
GACCTCGTCGTGCGGATTCTCGGGGGAGATCCCGCCGTCGGGCAGGAAGAGCTCACCATCGAGGAGTTCGGGCAACTGAT
CACCGGTCTCGGCGGCCTGACCGCCGAACAACGCACGATCCTGTCCGGTGCGCTGGAGATCCACGAGCGTTCACTGCGCG
AAGTCATCGTCCCCCGGACGGCGGTCTTCCGGCTGAACGGTGAGCTGTCGCTGCAGCGGGCTCGCACGGACCTCGCGGCG
TCCGGCCACACCAGGGCGCCGGTCGTGCGATCCGGAGAACTGGACGACGCCATCGGTGTGGTGCACCTGCGCGACCTGCT
GGGTGACGACGGCACCGTCGCCGAAGTCACCCGACCGGTGCTCAGACTGCCGGACAGTCTGCGCGTCACCATCGCGCTGC
GCCAACTGCTCGCCGCGCACGAGCATCTGGCGCTCGTCGTCGGCGAGCACGGCGGCGTCGACGGCATCGTCACCCTCGAG
GATCTGCTCGAGGAGATCGTCGGCGAGATCTACGACGAGGCCGACGAGGACATCCGAACCGCCGAAGCACTCCCGGACGG
CAGTCGAATTCTGCCGGGCACCTTCCCGATTCACGATCTGCCCGACATCGGGATCGAGTTCTCCGACGCACCTCCCGGCG
ACTACACCACGATCGCCGGACTCGTGCTGTCCCTGCTGGGGCGGATTCCGACGGTTCCCGGAGATCGCGTCGACCTTCCG
CCTTGCCGTGTCCAGGTCACAGGCGTCGGCCGCCATGCGATCACCGAGGTGCGCATTCTGCCTCGAGATCGGCGATGA

Upstream 100 bases:

>100_bases
GGCGATGACGCTCGTCAACCGCATCCTGACCGCGCAGACGCCGGGGGAGAGGCTCGGGTCAGCAAGGGACCGCGCCGTAG
CCGAGGGCTGAGACGACACG

Downstream 100 bases:

>100_bases
TGACCCGACAGGGGGGCGAAGGTGGCGCGTCGGGTCTCGAATGCAGCGCCTGATCCGGGAGAGCCGTGGGATTTTTCAAG
GTCGTGGCCGTCGACATCGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 425; Mature: 424

Protein sequence:

>425_residues
MSDYWLNVALVFALILVNGLLAGSEAAFISLREGQLRELEHRGGRRDLTVVGLAREPNRYLATIQLGITLAGFFASATAA
VTLAEPLAPLLGFLGAGAQTAVSIAVVTVLVAGVTLVFGELAPKRLAMQYARRWALVVASPLSAMSAVAAPIAWVLGRAT
DLVVRILGGDPAVGQEELTIEEFGQLITGLGGLTAEQRTILSGALEIHERSLREVIVPRTAVFRLNGELSLQRARTDLAA
SGHTRAPVVRSGELDDAIGVVHLRDLLGDDGTVAEVTRPVLRLPDSLRVTIALRQLLAAHEHLALVVGEHGGVDGIVTLE
DLLEEIVGEIYDEADEDIRTAEALPDGSRILPGTFPIHDLPDIGIEFSDAPPGDYTTIAGLVLSLLGRIPTVPGDRVDLP
PCRVQVTGVGRHAITEVRILPRDRR

Sequences:

>Translated_425_residues
MSDYWLNVALVFALILVNGLLAGSEAAFISLREGQLRELEHRGGRRDLTVVGLAREPNRYLATIQLGITLAGFFASATAA
VTLAEPLAPLLGFLGAGAQTAVSIAVVTVLVAGVTLVFGELAPKRLAMQYARRWALVVASPLSAMSAVAAPIAWVLGRAT
DLVVRILGGDPAVGQEELTIEEFGQLITGLGGLTAEQRTILSGALEIHERSLREVIVPRTAVFRLNGELSLQRARTDLAA
SGHTRAPVVRSGELDDAIGVVHLRDLLGDDGTVAEVTRPVLRLPDSLRVTIALRQLLAAHEHLALVVGEHGGVDGIVTLE
DLLEEIVGEIYDEADEDIRTAEALPDGSRILPGTFPIHDLPDIGIEFSDAPPGDYTTIAGLVLSLLGRIPTVPGDRVDLP
PCRVQVTGVGRHAITEVRILPRDRR
>Mature_424_residues
SDYWLNVALVFALILVNGLLAGSEAAFISLREGQLRELEHRGGRRDLTVVGLAREPNRYLATIQLGITLAGFFASATAAV
TLAEPLAPLLGFLGAGAQTAVSIAVVTVLVAGVTLVFGELAPKRLAMQYARRWALVVASPLSAMSAVAAPIAWVLGRATD
LVVRILGGDPAVGQEELTIEEFGQLITGLGGLTAEQRTILSGALEIHERSLREVIVPRTAVFRLNGELSLQRARTDLAAS
GHTRAPVVRSGELDDAIGVVHLRDLLGDDGTVAEVTRPVLRLPDSLRVTIALRQLLAAHEHLALVVGEHGGVDGIVTLED
LLEEIVGEIYDEADEDIRTAEALPDGSRILPGTFPIHDLPDIGIEFSDAPPGDYTTIAGLVLSLLGRIPTVPGDRVDLPP
CRVQVTGVGRHAITEVRILPRDRR

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=384, Percent_Identity=28.6458333333333, Blast_Score=163, Evalue=3e-40,
Organism=Homo sapiens, GI40068055, Length=376, Percent_Identity=24.468085106383, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI40068053, Length=376, Percent_Identity=24.468085106383, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI145693175, Length=415, Percent_Identity=26.0240963855422, Blast_Score=121, Evalue=9e-29,
Organism=Escherichia coli, GI1790664, Length=431, Percent_Identity=21.8097447795824, Blast_Score=118, Evalue=8e-28,
Organism=Escherichia coli, GI87082033, Length=276, Percent_Identity=30.0724637681159, Blast_Score=101, Evalue=9e-23,
Organism=Escherichia coli, GI1788119, Length=271, Percent_Identity=31.3653136531365, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1786879, Length=246, Percent_Identity=30.0813008130081, Blast_Score=80, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6324512, Length=259, Percent_Identity=27.4131274131274, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 45222; Mature: 45091

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDYWLNVALVFALILVNGLLAGSEAAFISLREGQLRELEHRGGRRDLTVVGLAREPNRY
CCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHCCCCCCEEEEEEECCCCCE
LATIQLGITLAGFFASATAAVTLAEPLAPLLGFLGAGAQTAVSIAVVTVLVAGVTLVFGE
EEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
LAPKRLAMQYARRWALVVASPLSAMSAVAAPIAWVLGRATDLVVRILGGDPAVGQEELTI
CCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCHHHHEEEEECCCCCCCCCCCCH
EEFGQLITGLGGLTAEQRTILSGALEIHERSLREVIVPRTAVFRLNGELSLQRARTDLAA
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEHHHHHHHHHC
SGHTRAPVVRSGELDDAIGVVHLRDLLGDDGTVAEVTRPVLRLPDSLRVTIALRQLLAAH
CCCCCCCEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHH
EHLALVVGEHGGVDGIVTLEDLLEEIVGEIYDEADEDIRTAEALPDGSRILPGTFPIHDL
HCEEEEEECCCCCCCEEEHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCEECCCCCCCCCC
PDIGIEFSDAPPGDYTTIAGLVLSLLGRIPTVPGDRVDLPPCRVQVTGVGRHAITEVRIL
CCCCEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCHHHEEEEEC
PRDRR
CCCCC
>Mature Secondary Structure 
SDYWLNVALVFALILVNGLLAGSEAAFISLREGQLRELEHRGGRRDLTVVGLAREPNRY
CCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHCCCCCCEEEEEEECCCCCE
LATIQLGITLAGFFASATAAVTLAEPLAPLLGFLGAGAQTAVSIAVVTVLVAGVTLVFGE
EEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
LAPKRLAMQYARRWALVVASPLSAMSAVAAPIAWVLGRATDLVVRILGGDPAVGQEELTI
CCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCHHHHEEEEECCCCCCCCCCCCH
EEFGQLITGLGGLTAEQRTILSGALEIHERSLREVIVPRTAVFRLNGELSLQRARTDLAA
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEHHHHHHHHHC
SGHTRAPVVRSGELDDAIGVVHLRDLLGDDGTVAEVTRPVLRLPDSLRVTIALRQLLAAH
CCCCCCCEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHH
EHLALVVGEHGGVDGIVTLEDLLEEIVGEIYDEADEDIRTAEALPDGSRILPGTFPIHDL
HCEEEEEECCCCCCCEEEHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCEECCCCCCCCCC
PDIGIEFSDAPPGDYTTIAGLVLSLLGRIPTVPGDRVDLPPCRVQVTGVGRHAITEVRIL
CCCCEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCHHHEEEEEC
PRDRR
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]