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The map label for this gene is thiO/thiG [H]

Identifier: 108797525

GI number: 108797525

Start: 604241

End: 605257

Strand: Direct

Name: thiO/thiG [H]

Synonym: Mmcs_0545

Alternate gene names: 108797525

Gene position: 604241-605257 (Clockwise)

Preceding gene: 108797523

Following gene: 108797526

Centisome position: 10.59

GC content: 72.66

Gene sequence:

>1017_bases
ATGCCACCGGACAGCACCCTCGCCGTCATCGGCGGCGGGGTCATCGGCCTGTCGGTCGCGCGCCGCGCCGCGCTCGACGG
TTGGTCGGTGCGGGTGCACCGCAGCCCCGCCAAGGGCGCGTCATGGGTGGCAGGCGGGATGCTCGCCCCGCACAGCGAGG
GCTGGCCGGGGGAACACGAACTGCTGCGCATCGGGCTGGATTCGCTGCGGCTGTGGCATGGCGGCTTCCTCGAGGGACTG
CCCGACGAGGTGGTGACCGCCCGGGAGTCACTGGTGGTGGCCGTGGACCGGGCCGACGCCGCCGATCTCAAGACCGTCGG
TGAATGGCTGGCCGTCCAGGGCCACCCTGTCACGTTCACGACGGCGGCCCGTGACATCGAACCGCTGCTGGCGCAGGGCA
TCCGGCACGGGTTCGTCGCCGACACCGAACTGGCCGTCGACAACCGCGCCGTCGTGGACGCGTTGGAGGCGCACTGCACC
CGACTCGGGGTGCGGTGGGCGCCGCCGGTCGACGATCTGGCTGCCGTCGACGACGTGGACCTGCGGGTGCTCGCCAACGG
CGTCGACGCACCGACGTTGTGGCCCGGGCTGCCGATCCGCCCGGTGAAAGGGGAGGTGCTGCGCCTGCGTTGGCGGCGCG
GGTGTATGCCTGCCCCGCGCCGGGTGGTTCGCGCCCGCGTCCACGGCAGGCAGGTGTATCTGGTGCCGCGCGCCGACGGC
GTGGTCGTCGGCGCGACCCAGTACGAACACGGGCGCGACACCGCACCCGCGGTGACCGGGGTTCGCGATCTGCTCGACGA
CGCGTGCACGGTCATGCCGGCACTGGGGGAATACGAGTTCGCCGAATGCGCGGCGGGGCTGCGGCCGATGACGCCCGACG
GGTTGCCTCTTGTCGAGTGGCTCGACGAGCGCACACTGGTGGCGGCAGGGCACGGCCGCAACGGCTTCCTGCTCGCGCCG
TGGACCGCCGAGCGGGTCTCCGCCGAACTGCAGACGACACAGGGAGCCAGGACATGA

Upstream 100 bases:

>100_bases
GCCGACACGGGAGTCCCGGGACAGCGGGACTGAGAGTGGGCCAGACGATCCGGCCCTTACCGTCGGACCTGATCCGGGTC
ATGCCGGCGAAGGGAGGGCC

Downstream 100 bases:

>100_bases
GGAGTCACGGATGAGGATCGTGGTGAACAACGAAGACGTCCACCTCGACGAGCAGACCACGGTCGCGCAGCTGGTGGCTC
GAATGGGGTTCCCGGAGAAG

Product: glycine oxidase ThiO

Products: NA

Alternate protein names: Probable FAD-dependent glycine oxidase; Thiazole synthase [H]

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MPPDSTLAVIGGGVIGLSVARRAALDGWSVRVHRSPAKGASWVAGGMLAPHSEGWPGEHELLRIGLDSLRLWHGGFLEGL
PDEVVTARESLVVAVDRADAADLKTVGEWLAVQGHPVTFTTAARDIEPLLAQGIRHGFVADTELAVDNRAVVDALEAHCT
RLGVRWAPPVDDLAAVDDVDLRVLANGVDAPTLWPGLPIRPVKGEVLRLRWRRGCMPAPRRVVRARVHGRQVYLVPRADG
VVVGATQYEHGRDTAPAVTGVRDLLDDACTVMPALGEYEFAECAAGLRPMTPDGLPLVEWLDERTLVAAGHGRNGFLLAP
WTAERVSAELQTTQGART

Sequences:

>Translated_338_residues
MPPDSTLAVIGGGVIGLSVARRAALDGWSVRVHRSPAKGASWVAGGMLAPHSEGWPGEHELLRIGLDSLRLWHGGFLEGL
PDEVVTARESLVVAVDRADAADLKTVGEWLAVQGHPVTFTTAARDIEPLLAQGIRHGFVADTELAVDNRAVVDALEAHCT
RLGVRWAPPVDDLAAVDDVDLRVLANGVDAPTLWPGLPIRPVKGEVLRLRWRRGCMPAPRRVVRARVHGRQVYLVPRADG
VVVGATQYEHGRDTAPAVTGVRDLLDDACTVMPALGEYEFAECAAGLRPMTPDGLPLVEWLDERTLVAAGHGRNGFLLAP
WTAERVSAELQTTQGART
>Mature_337_residues
PPDSTLAVIGGGVIGLSVARRAALDGWSVRVHRSPAKGASWVAGGMLAPHSEGWPGEHELLRIGLDSLRLWHGGFLEGLP
DEVVTARESLVVAVDRADAADLKTVGEWLAVQGHPVTFTTAARDIEPLLAQGIRHGFVADTELAVDNRAVVDALEAHCTR
LGVRWAPPVDDLAAVDDVDLRVLANGVDAPTLWPGLPIRPVKGEVLRLRWRRGCMPAPRRVVRARVHGRQVYLVPRADGV
VVGATQYEHGRDTAPAVTGVRDLLDDACTVMPALGEYEFAECAAGLRPMTPDGLPLVEWLDERTLVAAGHGRNGFLLAPW
TAERVSAELQTTQGART

Specific function: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S [H]

COG id: COG0665

COG function: function code E; Glycine/D-amino acid oxidases (deaminating)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the thiG family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006076
- InterPro:   IPR012727
- InterPro:   IPR008867 [H]

Pfam domain/function: PF01266 DAO; PF05690 ThiG [H]

EC number: NA

Molecular weight: Translated: 36262; Mature: 36131

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPDSTLAVIGGGVIGLSVARRAALDGWSVRVHRSPAKGASWVAGGMLAPHSEGWPGEHE
CCCCCEEEEECCCHHHHHHHHHHHCCCCEEEEECCCCCCCCHHCCCCCCCCCCCCCCHHH
LLRIGLDSLRLWHGGFLEGLPDEVVTARESLVVAVDRADAADLKTVGEWLAVQGHPVTFT
HHHHHHHHHHHHCCCHHCCCCHHHHHCCCEEEEEEECCCCHHHHHHHHHHEECCCCEEEE
TAARDIEPLLAQGIRHGFVADTELAVDNRAVVDALEAHCTRLGVRWAPPVDDLAAVDDVD
CCHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCC
LRVLANGVDAPTLWPGLPIRPVKGEVLRLRWRRGCMPAPRRVVRARVHGRQVYLVPRADG
EEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEEECCCC
VVVGATQYEHGRDTAPAVTGVRDLLDDACTVMPALGEYEFAECAAGLRPMTPDGLPLVEW
EEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCHHHHH
LDERTLVAAGHGRNGFLLAPWTAERVSAELQTTQGART
CCCCEEEEECCCCCCCEECCCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
PPDSTLAVIGGGVIGLSVARRAALDGWSVRVHRSPAKGASWVAGGMLAPHSEGWPGEHE
CCCCEEEEECCCHHHHHHHHHHHCCCCEEEEECCCCCCCCHHCCCCCCCCCCCCCCHHH
LLRIGLDSLRLWHGGFLEGLPDEVVTARESLVVAVDRADAADLKTVGEWLAVQGHPVTFT
HHHHHHHHHHHHCCCHHCCCCHHHHHCCCEEEEEEECCCCHHHHHHHHHHEECCCCEEEE
TAARDIEPLLAQGIRHGFVADTELAVDNRAVVDALEAHCTRLGVRWAPPVDDLAAVDDVD
CCHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCC
LRVLANGVDAPTLWPGLPIRPVKGEVLRLRWRRGCMPAPRRVVRARVHGRQVYLVPRADG
EEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEEECCCC
VVVGATQYEHGRDTAPAVTGVRDLLDDACTVMPALGEYEFAECAAGLRPMTPDGLPLVEW
EEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCHHHHH
LDERTLVAAGHGRNGFLLAPWTAERVSAELQTTQGART
CCCCEEEEECCCCCCCEECCCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]