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The map label for this gene is pntB [H]

Identifier: 108797081

GI number: 108797081

Start: 114221

End: 115660

Strand: Reverse

Name: pntB [H]

Synonym: Mmcs_0100

Alternate gene names: 108797081

Gene position: 115660-114221 (Counterclockwise)

Preceding gene: 108797082

Following gene: 108797080

Centisome position: 2.03

GC content: 67.22

Gene sequence:

>1440_bases
ATGTTGTCACTGGAAACCACCGCGACGGCGGCCTACGTCGTCGCGGCCATCCTGTTCATCCTCGCCCTGGCCGGACTGTC
CAAGCACGAGACCTCGAGGGCGGGTAACACCTTCGGCATCGCCGGGATGGCCGTCGCCCTGATCGCGACCATCGCGCTGG
CCCTCGATCACGACATCGAGCCGCTCGGCCTGGGGCTGCTGATCGGCGCCATGGTCATCGGCGCCGTGATCGGACTGTGG
CGCGCCAAGGTGGTCGAGATGACCGGTATGCCCGAACTGATCGCGCTGCTGCACTCGTTCGTCGGCCTGGCCGCCGTGCT
GGTCGGCTGGAACGGCTACCTGCATGTCGAGGGTCAGCCCGACGGCGCCGAGGCGGCCGCGATCGCCGCCGAAGGCATGC
TCGGCATCCACTCGGCCGAGGTCGTCATCGGTGTGTTCATCGGGGCGGTCACGTTCACCGGCTCGATCGTGGCCAACCTC
AAACTGTCGGCCCGGATCAAATCCGCGCCGATGATGCTGCCCGGTAAGAACGCTCTCAACGTCGGGGCTCTCGTGGCCTT
CGCCGCCCTGACGGTGTGGTTCGTCATCGATCCGCAGCTGTGGCTGCTCGTCGTGGTGACCGTGCTGGCGCTGCTGCTGG
GCTGGCACCTGGTCGCCTCGATCGGCGGCGGCGACATGCCCGTGGTGGTGTCGATGCTCAACAGCTACTCCGGCTGGGCC
GCCGCGGCGTCGGGCTTCCTGCTGGCCAACGACCTGCTGATCGTCACCGGCGCACTGGTCGGGTCCTCGGGCGCCTACCT
GTCCTACATCATGTGCAAGGCGATGAACCGGTCGTTCATCTCGGTGATCGCCGGAGGCTTCGGGATCGAGGCCGGGCCCG
CCGAGGACAAGGATTACGGCGAGCATCGGGAGATCAACGCCGAGGGCGCCGCCGAGCTGCTGTCCTCGGCCAGTTCGGTG
ATCATCACACCGGGCTACGGGATGGCCGTCGCCCAGGCCCAGTACGGGGTCGCCGACCTGACCCGCAAACTGCGCGAACG
GGGCGTCAACGTCCGGTTCGGCATCCATCCCGTCGCCGGCCGCCTGCCCGGCCACATGAACGTGCTGCTCGCCGAGGCCA
AGGTGCCCTACGACATCGTGCTCGAAATGGACGAGATCAACGACGACTTCGCCGACACCGACGTCGTACTCGTCATCGGC
GCCAACGACACCGTCAACCCCGCCGCATCCGAGGATCCGGGCAGCCCGATCGCCGGCATGCCCGTCCTCACGGTGTGGAA
CGCGAACCACGTCATCGTGTTCAAACGCTCCATGGCCTCCGGCTACGCCGGCGTGCAGAACCCGCTGTTCTTCCGCGACA
ACACCCAGATGCTGTTCGGTGACGCCAAAGACCGGGTCGACGCCATCAACGCGGCGCTCACGGTCCCCGAGAAGGTCTAG

Upstream 100 bases:

>100_bases
CGCAATCGCCACGGTGGCGATCCTGCTCGCCAGCATCAACGTCTTCGGTGGGTTCTCCGTGACCCGCCGCATGCTGGCCA
TGTTCTCGAGGAGCTGAGGA

Downstream 100 bases:

>100_bases
GTCAGATGCCGGTTGACCGTCTGCTGCCCTCCGACGAGGCGCGCGAGCTCATCGCGCTGACCCGTGACATCGCCGACAAG
GTGCTCGACCCCATCGTCGA

Product: NAD(P) transhydrogenase subunit beta

Products: NA

Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit beta; Pyridine nucleotide transhydrogenase subunit beta [H]

Number of amino acids: Translated: 479; Mature: 479

Protein sequence:

>479_residues
MLSLETTATAAYVVAAILFILALAGLSKHETSRAGNTFGIAGMAVALIATIALALDHDIEPLGLGLLIGAMVIGAVIGLW
RAKVVEMTGMPELIALLHSFVGLAAVLVGWNGYLHVEGQPDGAEAAAIAAEGMLGIHSAEVVIGVFIGAVTFTGSIVANL
KLSARIKSAPMMLPGKNALNVGALVAFAALTVWFVIDPQLWLLVVVTVLALLLGWHLVASIGGGDMPVVVSMLNSYSGWA
AAASGFLLANDLLIVTGALVGSSGAYLSYIMCKAMNRSFISVIAGGFGIEAGPAEDKDYGEHREINAEGAAELLSSASSV
IITPGYGMAVAQAQYGVADLTRKLRERGVNVRFGIHPVAGRLPGHMNVLLAEAKVPYDIVLEMDEINDDFADTDVVLVIG
ANDTVNPAASEDPGSPIAGMPVLTVWNANHVIVFKRSMASGYAGVQNPLFFRDNTQMLFGDAKDRVDAINAALTVPEKV

Sequences:

>Translated_479_residues
MLSLETTATAAYVVAAILFILALAGLSKHETSRAGNTFGIAGMAVALIATIALALDHDIEPLGLGLLIGAMVIGAVIGLW
RAKVVEMTGMPELIALLHSFVGLAAVLVGWNGYLHVEGQPDGAEAAAIAAEGMLGIHSAEVVIGVFIGAVTFTGSIVANL
KLSARIKSAPMMLPGKNALNVGALVAFAALTVWFVIDPQLWLLVVVTVLALLLGWHLVASIGGGDMPVVVSMLNSYSGWA
AAASGFLLANDLLIVTGALVGSSGAYLSYIMCKAMNRSFISVIAGGFGIEAGPAEDKDYGEHREINAEGAAELLSSASSV
IITPGYGMAVAQAQYGVADLTRKLRERGVNVRFGIHPVAGRLPGHMNVLLAEAKVPYDIVLEMDEINDDFADTDVVLVIG
ANDTVNPAASEDPGSPIAGMPVLTVWNANHVIVFKRSMASGYAGVQNPLFFRDNTQMLFGDAKDRVDAINAALTVPEKV
>Mature_479_residues
MLSLETTATAAYVVAAILFILALAGLSKHETSRAGNTFGIAGMAVALIATIALALDHDIEPLGLGLLIGAMVIGAVIGLW
RAKVVEMTGMPELIALLHSFVGLAAVLVGWNGYLHVEGQPDGAEAAAIAAEGMLGIHSAEVVIGVFIGAVTFTGSIVANL
KLSARIKSAPMMLPGKNALNVGALVAFAALTVWFVIDPQLWLLVVVTVLALLLGWHLVASIGGGDMPVVVSMLNSYSGWA
AAASGFLLANDLLIVTGALVGSSGAYLSYIMCKAMNRSFISVIAGGFGIEAGPAEDKDYGEHREINAEGAAELLSSASSV
IITPGYGMAVAQAQYGVADLTRKLRERGVNVRFGIHPVAGRLPGHMNVLLAEAKVPYDIVLEMDEINDDFADTDVVLVIG
ANDTVNPAASEDPGSPIAGMPVLTVWNANHVIVFKRSMASGYAGVQNPLFFRDNTQMLFGDAKDRVDAINAALTVPEKV

Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]

COG id: COG1282

COG function: function code C; NAD/NADP transhydrogenase beta subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNT beta subunit family [H]

Homologues:

Organism=Homo sapiens, GI122939155, Length=466, Percent_Identity=51.0729613733906, Blast_Score=438, Evalue=1e-123,
Organism=Homo sapiens, GI122939153, Length=466, Percent_Identity=51.0729613733906, Blast_Score=438, Evalue=1e-123,
Organism=Escherichia coli, GI1787886, Length=470, Percent_Identity=70.4255319148936, Blast_Score=624, Evalue=1e-180,
Organism=Caenorhabditis elegans, GI17550456, Length=466, Percent_Identity=49.3562231759657, Blast_Score=392, Evalue=1e-109,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012136
- InterPro:   IPR004003 [H]

Pfam domain/function: PF02233 PNTB [H]

EC number: =1.6.1.2 [H]

Molecular weight: Translated: 49795; Mature: 49795

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSLETTATAAYVVAAILFILALAGLSKHETSRAGNTFGIAGMAVALIATIALALDHDIE
CCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCC
PLGLGLLIGAMVIGAVIGLWRAKVVEMTGMPELIALLHSFVGLAAVLVGWNGYLHVEGQP
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
DGAEAAAIAAEGMLGIHSAEVVIGVFIGAVTFTGSIVANLKLSARIKSAPMMLPGKNALN
CCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCHHEEEEEEEEEECCCCEECCCCCCCH
VGALVAFAALTVWFVIDPQLWLLVVVTVLALLLGWHLVASIGGGDMPVVVSMLNSYSGWA
HHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHH
AAASGFLLANDLLIVTGALVGSSGAYLSYIMCKAMNRSFISVIAGGFGIEAGPAEDKDYG
HHHCCHHHCCCHHHEEHHHHCCCCHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCCCCCC
EHREINAEGAAELLSSASSVIITPGYGMAVAQAQYGVADLTRKLRERGVNVRFGIHPVAG
CCCCCCCHHHHHHHCCCCCEEEECCCCCHHHHHHCCHHHHHHHHHHCCCCEEEECCHHCC
RLPGHMNVLLAEAKVPYDIVLEMDEINDDFADTDVVLVIGANDTVNPAASEDPGSPIAGM
CCCCCCEEEEEECCCCEEEEEEEHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCC
PVLTVWNANHVIVFKRSMASGYAGVQNPLFFRDNTQMLFGDAKDRVDAINAALTVPEKV
CEEEEECCCEEEEEEECCCCCCCCCCCCEEEECCCEEEECCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLSLETTATAAYVVAAILFILALAGLSKHETSRAGNTFGIAGMAVALIATIALALDHDIE
CCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCC
PLGLGLLIGAMVIGAVIGLWRAKVVEMTGMPELIALLHSFVGLAAVLVGWNGYLHVEGQP
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
DGAEAAAIAAEGMLGIHSAEVVIGVFIGAVTFTGSIVANLKLSARIKSAPMMLPGKNALN
CCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCHHEEEEEEEEEECCCCEECCCCCCCH
VGALVAFAALTVWFVIDPQLWLLVVVTVLALLLGWHLVASIGGGDMPVVVSMLNSYSGWA
HHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHH
AAASGFLLANDLLIVTGALVGSSGAYLSYIMCKAMNRSFISVIAGGFGIEAGPAEDKDYG
HHHCCHHHCCCHHHEEHHHHCCCCHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCCCCCC
EHREINAEGAAELLSSASSVIITPGYGMAVAQAQYGVADLTRKLRERGVNVRFGIHPVAG
CCCCCCCHHHHHHHCCCCCEEEECCCCCHHHHHHCCHHHHHHHHHHCCCCEEEECCHHCC
RLPGHMNVLLAEAKVPYDIVLEMDEINDDFADTDVVLVIGANDTVNPAASEDPGSPIAGM
CCCCCCEEEEEECCCCEEEEEEEHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCC
PVLTVWNANHVIVFKRSMASGYAGVQNPLFFRDNTQMLFGDAKDRVDAINAALTVPEKV
CEEEEECCCEEEEEEECCCCCCCCCCCCEEEECCCEEEECCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]