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The map label for this gene is fruA [H]

Identifier: 108797061

GI number: 108797061

Start: 92634

End: 94649

Strand: Reverse

Name: fruA [H]

Synonym: Mmcs_0080

Alternate gene names: 108797061

Gene position: 94649-92634 (Counterclockwise)

Preceding gene: 108797062

Following gene: 108797060

Centisome position: 1.66

GC content: 70.93

Gene sequence:

>2016_bases
ATGTCCAGTCCCACCGCATCGCCGATCATCACCACCGATCTCGTGCTGCTCGACGTCGACGCCGGCGGCGACAAGGAAGC
CGTGATCGGCCGCCTCGTCAACCGGCTGGCCGACGCCGGGCGCAGCACCGACGCCGACGGTCTGACACGCGCCGCGCTGG
CCCGGGAGGAACAGTCGGCGACCGGCCTACCCGGCGGCATCGCGATCCCGCACTGCCGCTCCCCGTATGTCGACACCGCG
ACGATCGGTTTCGCGCGCCTGACCCCCGGTGTGGACTTCGGAGCCCCCGACGGGCCGGCCGACCTGGTGTTCCTGATCGC
CGCACCGGATTCCGGCGGCGCCGAGCACATGAAGCTGCTGTCGAGCCTCGCGCGCGCCCTGGTGCGCAAGGAGTTCGTCG
CCTCGCTGCGCGCGGCCGAGACGTCCGAGGACGTCGTCTCTCTGGTCGAGGACGTGGTCAACCCGCAAGCGGCGGCACCG
CCGCCGCCCGCCGCGGAGCCGGAACCGGCCAGGCAGCGCTCACTCGTCGCCGTCACCGCCTGCCCGACCGGCATCGCGCA
CACCTACATGGCGGCCGATTCGCTGGCCGCCGCCGCGAAGAACGCCGGCGTCACGCTGCATGTGGAGACCCAGGGTTCCT
CGGGCAGCACGCCGCTGTCGGACGCGACGATCGCCGAAGCCGACGCGGTCATCTTCGCCACCGACGTGGGGGTGAAGGAC
CGGCAGCGCTTCGCGGGCAAACCCGTCGTCGCCTCGGGGGTCAAGCGGGCGATCAACGAACCGGACAAGATGGTCGCCGA
CGCACTGGCCGCCGCGGACAACCCCGACGCCGCCCGCGTCGAGGGTTCCGCCGGCGCCCCCTCGGCGGCGGCGCCCGCGG
GTGATGTCGGCTGGGGCACGCGCACCCGGCAGATCCTGCTGACCGGTGTGAGCTACATGATCCCGTTCGTCGCCGCGGGC
GGTCTGCTGATCGCGCTGGGCTTCCTGTTCGCGGGTTACGACATCGCGAATACGCCTGACGGCCAGACGGATTCACTCGG
CAAGATCATCGCGACGACGAACTCGCTGACCAACCTGCCGTCCGGCGGGCTGATCCAGTACCTCGGTGCGGTGCTGTTCA
CGATCGGGAACCTGGCGTTCTTCTTCCTGGTACCCGCGCTGGCCGGGTACATCGCGTTCGCCATCGCCGACCGGCCCGGT
ATCGCACCCGGCTTCGTCGCCGGTTACATCGCCACCACGGTGGGCGCCGGGTTCATCGGCGGCATCGTCGGCGGCCTGAT
CGCCGGTTTCGCCGCGCTGTGGATCAGTCGGATCGGGGTACCGCACTGGGCCCGCGGGCTGATGCCGGTGGTGATCATCC
CGCTGTTCGCCTCACTGGTCGTGGGCCTGCTGATGTTCCTGCTGCTCGGCCGTCCGCTGGCGTGGCTCACCACCAGCCTC
ACCGACTGGCTCAACGGGCTGTCCGGTAGTTCGGTGATCGTGCTCGGCGTCATCCTCGGCTTGATGATGTGCTTCGATCT
CGGCGGTCCGGTGAACAAGGCGGCGTACGCCTTCGCGACCACCGGCCTCAACGTGGCCGACCCGGCGTCGCTGCGGATCA
TGGCGGCGGTGATGGCCGCCGGGATGGTCCCGCCGCTGGCGATGGCGCTCGCCTCGACAGTGCGGCCCGGGTTGTTCACC
GAGCCGGAGCGCGAAAACGGCCGCGCCGCATGGCTGCTCGGGGCGTCGTTCATCTCCGAGGGCGCGATCCCCTTCGCGGC
GGCCGACCCGCTGCGCGTCATCCCGTCGATGATGTTCGGCGGCGCCATCACCGGTGCGCTGGTCATGGCGTTCGACGTCA
CCTCCAAGGCGCCCCACGGCGGCATCTTCGTGTTCTTCGCGATCGGCAACCTGGCGTGGTTCCTGGTCGCGCTCGCGGTG
GGCACCGCGGCCGGCGCCGGCGCCGTCGTCGCGGCCAAGCAGTTCGCCAAACCCGAAACGCCCGCCGACGCCAGCCCCGC
ACTCGCCAACGCCTGA

Upstream 100 bases:

>100_bases
CCGCACTGCCGTCCCCCGCCCAGCTCGACCTCGACGGCGTCGCCGTCAGCACCATCGCCCCGACCCCTGCCAGCTCGTGA
ACCGACCGAAAGAGCCCGTG

Downstream 100 bases:

>100_bases
GCCCCACCCCAGAAAAGGAAACCCCACCATGCCCGCACGTACCGTCACCGTCGGCTCGGCCATCGGCCTGCACGCCCGCC
CCGCCGCGATCATCGCCGAA

Product: phosphotransferase system, fructose IIC component

Products: NA

Alternate protein names: EIIABC-Fru; Fructose-specific phosphotransferase enzyme IIA component; EII-Fru; PTS system fructose-specific EIIA component; Fructose-specific phosphotransferase enzyme IIB component; EIII-Fru; PTS system fructose-specific EIIB component; Fructose permease IIC component; PTS system fructose-specific EIIC component [H]

Number of amino acids: Translated: 671; Mature: 670

Protein sequence:

>671_residues
MSSPTASPIITTDLVLLDVDAGGDKEAVIGRLVNRLADAGRSTDADGLTRAALAREEQSATGLPGGIAIPHCRSPYVDTA
TIGFARLTPGVDFGAPDGPADLVFLIAAPDSGGAEHMKLLSSLARALVRKEFVASLRAAETSEDVVSLVEDVVNPQAAAP
PPPAAEPEPARQRSLVAVTACPTGIAHTYMAADSLAAAAKNAGVTLHVETQGSSGSTPLSDATIAEADAVIFATDVGVKD
RQRFAGKPVVASGVKRAINEPDKMVADALAAADNPDAARVEGSAGAPSAAAPAGDVGWGTRTRQILLTGVSYMIPFVAAG
GLLIALGFLFAGYDIANTPDGQTDSLGKIIATTNSLTNLPSGGLIQYLGAVLFTIGNLAFFFLVPALAGYIAFAIADRPG
IAPGFVAGYIATTVGAGFIGGIVGGLIAGFAALWISRIGVPHWARGLMPVVIIPLFASLVVGLLMFLLLGRPLAWLTTSL
TDWLNGLSGSSVIVLGVILGLMMCFDLGGPVNKAAYAFATTGLNVADPASLRIMAAVMAAGMVPPLAMALASTVRPGLFT
EPERENGRAAWLLGASFISEGAIPFAAADPLRVIPSMMFGGAITGALVMAFDVTSKAPHGGIFVFFAIGNLAWFLVALAV
GTAAGAGAVVAAKQFAKPETPADASPALANA

Sequences:

>Translated_671_residues
MSSPTASPIITTDLVLLDVDAGGDKEAVIGRLVNRLADAGRSTDADGLTRAALAREEQSATGLPGGIAIPHCRSPYVDTA
TIGFARLTPGVDFGAPDGPADLVFLIAAPDSGGAEHMKLLSSLARALVRKEFVASLRAAETSEDVVSLVEDVVNPQAAAP
PPPAAEPEPARQRSLVAVTACPTGIAHTYMAADSLAAAAKNAGVTLHVETQGSSGSTPLSDATIAEADAVIFATDVGVKD
RQRFAGKPVVASGVKRAINEPDKMVADALAAADNPDAARVEGSAGAPSAAAPAGDVGWGTRTRQILLTGVSYMIPFVAAG
GLLIALGFLFAGYDIANTPDGQTDSLGKIIATTNSLTNLPSGGLIQYLGAVLFTIGNLAFFFLVPALAGYIAFAIADRPG
IAPGFVAGYIATTVGAGFIGGIVGGLIAGFAALWISRIGVPHWARGLMPVVIIPLFASLVVGLLMFLLLGRPLAWLTTSL
TDWLNGLSGSSVIVLGVILGLMMCFDLGGPVNKAAYAFATTGLNVADPASLRIMAAVMAAGMVPPLAMALASTVRPGLFT
EPERENGRAAWLLGASFISEGAIPFAAADPLRVIPSMMFGGAITGALVMAFDVTSKAPHGGIFVFFAIGNLAWFLVALAV
GTAAGAGAVVAAKQFAKPETPADASPALANA
>Mature_670_residues
SSPTASPIITTDLVLLDVDAGGDKEAVIGRLVNRLADAGRSTDADGLTRAALAREEQSATGLPGGIAIPHCRSPYVDTAT
IGFARLTPGVDFGAPDGPADLVFLIAAPDSGGAEHMKLLSSLARALVRKEFVASLRAAETSEDVVSLVEDVVNPQAAAPP
PPAAEPEPARQRSLVAVTACPTGIAHTYMAADSLAAAAKNAGVTLHVETQGSSGSTPLSDATIAEADAVIFATDVGVKDR
QRFAGKPVVASGVKRAINEPDKMVADALAAADNPDAARVEGSAGAPSAAAPAGDVGWGTRTRQILLTGVSYMIPFVAAGG
LLIALGFLFAGYDIANTPDGQTDSLGKIIATTNSLTNLPSGGLIQYLGAVLFTIGNLAFFFLVPALAGYIAFAIADRPGI
APGFVAGYIATTVGAGFIGGIVGGLIAGFAALWISRIGVPHWARGLMPVVIIPLFASLVVGLLMFLLLGRPLAWLTTSLT
DWLNGLSGSSVIVLGVILGLMMCFDLGGPVNKAAYAFATTGLNVADPASLRIMAAVMAAGMVPPLAMALASTVRPGLFTE
PERENGRAAWLLGASFISEGAIPFAAADPLRVIPSMMFGGAITGALVMAFDVTSKAPHGGIFVFFAIGNLAWFLVALAVG
TAAGAGAVVAAKQFAKPETPADASPALANA

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1299

COG function: function code G; Phosphotransferase system, fructose-specific IIC component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1788492, Length=480, Percent_Identity=44.5833333333333, Blast_Score=339, Evalue=3e-94,
Organism=Escherichia coli, GI1786951, Length=639, Percent_Identity=34.8982785602504, Blast_Score=336, Evalue=2e-93,
Organism=Escherichia coli, GI87082348, Length=497, Percent_Identity=33.1991951710262, Blast_Score=221, Evalue=1e-58,
Organism=Escherichia coli, GI1790386, Length=312, Percent_Identity=41.025641025641, Blast_Score=214, Evalue=1e-56,
Organism=Escherichia coli, GI1788729, Length=412, Percent_Identity=25.2427184466019, Blast_Score=90, Evalue=5e-19,
Organism=Escherichia coli, GI1790387, Length=90, Percent_Identity=47.7777777777778, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1788726, Length=143, Percent_Identity=32.1678321678322, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI48994992, Length=143, Percent_Identity=31.4685314685315, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI2367327, Length=146, Percent_Identity=26.7123287671233, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1788730, Length=102, Percent_Identity=38.2352941176471, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016152
- InterPro:   IPR002178
- InterPro:   IPR013011
- InterPro:   IPR003501
- InterPro:   IPR003352
- InterPro:   IPR013014
- InterPro:   IPR004715
- InterPro:   IPR003353
- InterPro:   IPR006327 [H]

Pfam domain/function: PF00359 PTS_EIIA_2; PF02378 PTS_EIIC; PF02302 PTS_IIB [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 67937; Mature: 67806

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS51094 PTS_EIIA_TYPE_2 ; PS51099 PTS_EIIB_TYPE_2 ; PS51104 PTS_EIIC_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSPTASPIITTDLVLLDVDAGGDKEAVIGRLVNRLADAGRSTDADGLTRAALAREEQSA
CCCCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHC
TGLPGGIAIPHCRSPYVDTATIGFARLTPGVDFGAPDGPADLVFLIAAPDSGGAEHMKLL
CCCCCCCCCCCCCCCCCCHHHCCHHHCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHH
SSLARALVRKEFVASLRAAETSEDVVSLVEDVVNPQAAAPPPPAAEPEPARQRSLVAVTA
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHCCEEEEEE
CPTGIAHTYMAADSLAAAAKNAGVTLHVETQGSSGSTPLSDATIAEADAVIFATDVGVKD
CCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCHHHCCCEEEEEECCCCHH
RQRFAGKPVVASGVKRAINEPDKMVADALAAADNPDAARVEGSAGAPSAAAPAGDVGWGT
HHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCEECCCCCCCCCCCCCCCCCCCC
RTRQILLTGVSYMIPFVAAGGLLIALGFLFAGYDIANTPDGQTDSLGKIIATTNSLTNLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHEEECCHHCCCC
SGGLIQYLGAVLFTIGNLAFFFLVPALAGYIAFAIADRPGIAPGFVAGYIATTVGAGFIG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
GIVGGLIAGFAALWISRIGVPHWARGLMPVVIIPLFASLVVGLLMFLLLGRPLAWLTTSL
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
TDWLNGLSGSSVIVLGVILGLMMCFDLGGPVNKAAYAFATTGLNVADPASLRIMAAVMAA
HHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
GMVPPLAMALASTVRPGLFTEPERENGRAAWLLGASFISEGAIPFAAADPLRVIPSMMFG
CCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEHHHHHCCCCCCCCCCHHHHHHHHHHH
GAITGALVMAFDVTSKAPHGGIFVFFAIGNLAWFLVALAVGTAAGAGAVVAAKQFAKPET
HHHHHHHHHHEECCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCC
PADASPALANA
CCCCCCCCCCC
>Mature Secondary Structure 
SSPTASPIITTDLVLLDVDAGGDKEAVIGRLVNRLADAGRSTDADGLTRAALAREEQSA
CCCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHC
TGLPGGIAIPHCRSPYVDTATIGFARLTPGVDFGAPDGPADLVFLIAAPDSGGAEHMKLL
CCCCCCCCCCCCCCCCCCHHHCCHHHCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHH
SSLARALVRKEFVASLRAAETSEDVVSLVEDVVNPQAAAPPPPAAEPEPARQRSLVAVTA
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHCCEEEEEE
CPTGIAHTYMAADSLAAAAKNAGVTLHVETQGSSGSTPLSDATIAEADAVIFATDVGVKD
CCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCHHHCCCEEEEEECCCCHH
RQRFAGKPVVASGVKRAINEPDKMVADALAAADNPDAARVEGSAGAPSAAAPAGDVGWGT
HHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCEECCCCCCCCCCCCCCCCCCCC
RTRQILLTGVSYMIPFVAAGGLLIALGFLFAGYDIANTPDGQTDSLGKIIATTNSLTNLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHEEECCHHCCCC
SGGLIQYLGAVLFTIGNLAFFFLVPALAGYIAFAIADRPGIAPGFVAGYIATTVGAGFIG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
GIVGGLIAGFAALWISRIGVPHWARGLMPVVIIPLFASLVVGLLMFLLLGRPLAWLTTSL
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
TDWLNGLSGSSVIVLGVILGLMMCFDLGGPVNKAAYAFATTGLNVADPASLRIMAAVMAA
HHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
GMVPPLAMALASTVRPGLFTEPERENGRAAWLLGASFISEGAIPFAAADPLRVIPSMMFG
CCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEHHHHHCCCCCCCCCCHHHHHHHHHHH
GAITGALVMAFDVTSKAPHGGIFVFFAIGNLAWFLVALAVGTAAGAGAVVAAKQFAKPET
HHHHHHHHHHEECCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCC
PADASPALANA
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]