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The map label for this gene is eccE1 [H]

Identifier: 108797058

GI number: 108797058

Start: 89417

End: 90814

Strand: Reverse

Name: eccE1 [H]

Synonym: Mmcs_0077

Alternate gene names: 108797058

Gene position: 90814-89417 (Counterclockwise)

Preceding gene: 108797059

Following gene: 108797057

Centisome position: 1.59

GC content: 68.88

Gene sequence:

>1398_bases
ATGAGGTCGTTCGTCGCGCAGTTCGGTCTACGCCTGACCACCGGCCACCTGATGTGGGCGGCGGTGCTGATCCCGGCGTG
CATCGCGATCTTCGTACCGCTGGACCTGCTGTGGGTCGGCGTCACGGTCTCGGTGCTGATCGCGCTGATCGCGGTCGTGA
CCGTCCGCGGGCGCCGGTTGACGGGCTGGGTGGCGGCCCTGTTCTCGTGGCGGCGCAGGCACCTCAGTACGCCACCCGCA
CCGTCGGAACCCGCGGTCGGCTCGACGGTCATGCCCGGCGACCACGTGGCGGTGCGCTGGCAGGGCGACCATCTGATGTC
GGCGATCGAACTGGTGCCGCGGCCGTTCACCCCGACCGTCGTGGTCAACGGACAGTCCTTCACCGATGACGTACTCGACA
CCGCGCTGGTGGAGAACCTGATCGCCGCGCACTGCCCGGAACTCGAAGCCGACGTGGTCGCCGCCGGATACCGGGTGGGC
AAGACCGCGCCGGCCAGCCTGGTGGCGCTCTACGAACAGGTGGTCGGACCGTATCCCGCGCCGGCGAACCGCCGCACGTG
GATCGTGCTGCGGGCCGATCCCGAACTGACCCGCAAACCCGCACAGCGCCGCGACTCCGGTGTCGCCGGGCTGGCCCGCT
ATCTGGTGGCCTCGACGACGCGGCTCGCGGATCAGTTGGCAGGCAACGGAATCGACGCCCGACCCAGCCGCAGCTTCGAC
GACTTCGACCGGGCCACCGAGGTCAGCTTCGAACGGGAGACCTGGTCGGCGATCAAGGGCCGCAGCACATTCACCGCGGC
GTACAGCGCGCCCGGCGGGCCCGATGTGTGGTGGTCGGCGCGCGCCGACCACACCATCACCCGGATGCGGATCCGCCCGG
GTATCGCCCCGACGACCACCGTACTGTTGACCACCTTGGCGAATCCGGCTACGCCGCGTGGCTTTTCGTGCCTGTTCGGC
GGCCAGCGCGCGGCGCTGCAGGGCATCAGCCCGGTGTCGGACAAACACTACGAGCTCCCGATCGGCTCGGCGGGGATTCT
GATCGGCGAGACCGCCGACCGCTATCCGGTGTACATGCCGTTCGACGACGTCGATGTCAGCATCAACCTCGGCGATGCCC
GACTGTTCACCCAGTTCGTGGTCCGGTCCGCCGCGGCGGGTGCGGTGGTGACGCTCGGCCCGCAGTTCCGCGAGTTCGCC
GGCTTCGTCAACGGACGCATCGGCCAGGAGGCCAAGCTGTCGTGGCCGAACGCGACGACCTATCTGAGCCCGCATCCCGG
TGTCGGCCGGGTGATACTGCGACACAACTTCATCGACACCCCGAGGCACCGGCAGTTGCCCATCCGGTTGATCAACCCGC
GCGAGGAAAGCCGCTACCAGATGGCACTCGAGCAGTGA

Upstream 100 bases:

>100_bases
CGCCCGACCGCGGGCCGATCACCTGGGTGGTCGTGATCGGGGCGGGTCTGACGCTGGTCCTCGGCATCGCCGCGCTGACC
CGGCGGGCGTTGAGGCGCCG

Downstream 100 bases:

>100_bases
CCACCTGTTGGCCGGCCGCCCCGACACCGCGGTGACCTGAGGAGGAAGACATGGCGGGGGACGAAGTCCGAGTCGAACCT
GCGGATCTGCGGGCTCGAGC

Product: hypothetical protein

Products: NA

Alternate protein names: ESX conserved component E1; Type VII secretion system protein EccE1; T7SS protein EccE1 [H]

Number of amino acids: Translated: 465; Mature: 465

Protein sequence:

>465_residues
MRSFVAQFGLRLTTGHLMWAAVLIPACIAIFVPLDLLWVGVTVSVLIALIAVVTVRGRRLTGWVAALFSWRRRHLSTPPA
PSEPAVGSTVMPGDHVAVRWQGDHLMSAIELVPRPFTPTVVVNGQSFTDDVLDTALVENLIAAHCPELEADVVAAGYRVG
KTAPASLVALYEQVVGPYPAPANRRTWIVLRADPELTRKPAQRRDSGVAGLARYLVASTTRLADQLAGNGIDARPSRSFD
DFDRATEVSFERETWSAIKGRSTFTAAYSAPGGPDVWWSARADHTITRMRIRPGIAPTTTVLLTTLANPATPRGFSCLFG
GQRAALQGISPVSDKHYELPIGSAGILIGETADRYPVYMPFDDVDVSINLGDARLFTQFVVRSAAAGAVVTLGPQFREFA
GFVNGRIGQEAKLSWPNATTYLSPHPGVGRVILRHNFIDTPRHRQLPIRLINPREESRYQMALEQ

Sequences:

>Translated_465_residues
MRSFVAQFGLRLTTGHLMWAAVLIPACIAIFVPLDLLWVGVTVSVLIALIAVVTVRGRRLTGWVAALFSWRRRHLSTPPA
PSEPAVGSTVMPGDHVAVRWQGDHLMSAIELVPRPFTPTVVVNGQSFTDDVLDTALVENLIAAHCPELEADVVAAGYRVG
KTAPASLVALYEQVVGPYPAPANRRTWIVLRADPELTRKPAQRRDSGVAGLARYLVASTTRLADQLAGNGIDARPSRSFD
DFDRATEVSFERETWSAIKGRSTFTAAYSAPGGPDVWWSARADHTITRMRIRPGIAPTTTVLLTTLANPATPRGFSCLFG
GQRAALQGISPVSDKHYELPIGSAGILIGETADRYPVYMPFDDVDVSINLGDARLFTQFVVRSAAAGAVVTLGPQFREFA
GFVNGRIGQEAKLSWPNATTYLSPHPGVGRVILRHNFIDTPRHRQLPIRLINPREESRYQMALEQ
>Mature_465_residues
MRSFVAQFGLRLTTGHLMWAAVLIPACIAIFVPLDLLWVGVTVSVLIALIAVVTVRGRRLTGWVAALFSWRRRHLSTPPA
PSEPAVGSTVMPGDHVAVRWQGDHLMSAIELVPRPFTPTVVVNGQSFTDDVLDTALVENLIAAHCPELEADVVAAGYRVG
KTAPASLVALYEQVVGPYPAPANRRTWIVLRADPELTRKPAQRRDSGVAGLARYLVASTTRLADQLAGNGIDARPSRSFD
DFDRATEVSFERETWSAIKGRSTFTAAYSAPGGPDVWWSARADHTITRMRIRPGIAPTTTVLLTTLANPATPRGFSCLFG
GQRAALQGISPVSDKHYELPIGSAGILIGETADRYPVYMPFDDVDVSINLGDARLFTQFVVRSAAAGAVVTLGPQFREFA
GFVNGRIGQEAKLSWPNATTYLSPHPGVGRVILRHNFIDTPRHRQLPIRLINPREESRYQMALEQ

Specific function: Could be part of a complex that is involved in secretion of ESX-1 substrates, such as EsxA (ESAT-6) and EsxB (CFP-10) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EccE family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR021368 [H]

Pfam domain/function: PF11203 DUF2984 [H]

EC number: NA

Molecular weight: Translated: 50697; Mature: 50697

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSFVAQFGLRLTTGHLMWAAVLIPACIAIFVPLDLLWVGVTVSVLIALIAVVTVRGRRL
CCCHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
TGWVAALFSWRRRHLSTPPAPSEPAVGSTVMPGDHVAVRWQGDHLMSAIELVPRPFTPTV
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHCCCCCCCEE
VVNGQSFTDDVLDTALVENLIAAHCPELEADVVAAGYRVGKTAPASLVALYEQVVGPYPA
EECCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCC
PANRRTWIVLRADPELTRKPAQRRDSGVAGLARYLVASTTRLADQLAGNGIDARPSRSFD
CCCCEEEEEEECCCHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
DFDRATEVSFERETWSAIKGRSTFTAAYSAPGGPDVWWSARADHTITRMRIRPGIAPTTT
HHHHHHHCCCCHHHHHHHCCCCEEEEEECCCCCCCCEEECCCCCEEEEEEECCCCCHHHH
VLLTTLANPATPRGFSCLFGGQRAALQGISPVSDKHYELPIGSAGILIGETADRYPVYMP
HHHHHHCCCCCCCCCEEEECCCHHHHCCCCCCCCCCEECCCCCCCEEEECCCCCCEEEEC
FDDVDVSINLGDARLFTQFVVRSAAAGAVVTLGPQFREFAGFVNGRIGQEAKLSWPNATT
CCCCEEEEECCHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHCCCCCCCCEECCCCCCE
YLSPHPGVGRVILRHNFIDTPRHRQLPIRLINPREESRYQMALEQ
EECCCCCCCEEEEECCCCCCCCCCCCCEEEECCCHHHHHHHHCCC
>Mature Secondary Structure
MRSFVAQFGLRLTTGHLMWAAVLIPACIAIFVPLDLLWVGVTVSVLIALIAVVTVRGRRL
CCCHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
TGWVAALFSWRRRHLSTPPAPSEPAVGSTVMPGDHVAVRWQGDHLMSAIELVPRPFTPTV
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHCCCCCCCEE
VVNGQSFTDDVLDTALVENLIAAHCPELEADVVAAGYRVGKTAPASLVALYEQVVGPYPA
EECCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCC
PANRRTWIVLRADPELTRKPAQRRDSGVAGLARYLVASTTRLADQLAGNGIDARPSRSFD
CCCCEEEEEEECCCHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
DFDRATEVSFERETWSAIKGRSTFTAAYSAPGGPDVWWSARADHTITRMRIRPGIAPTTT
HHHHHHHCCCCHHHHHHHCCCCEEEEEECCCCCCCCEEECCCCCEEEEEEECCCCCHHHH
VLLTTLANPATPRGFSCLFGGQRAALQGISPVSDKHYELPIGSAGILIGETADRYPVYMP
HHHHHHCCCCCCCCCEEEECCCHHHHCCCCCCCCCCEECCCCCCCEEEECCCCCCEEEEC
FDDVDVSINLGDARLFTQFVVRSAAAGAVVTLGPQFREFAGFVNGRIGQEAKLSWPNATT
CCCCEEEEECCHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHCCCCCCCCEECCCCCCE
YLSPHPGVGRVILRHNFIDTPRHRQLPIRLINPREESRYQMALEQ
EECCCCCCCEEEEECCCCCCCCCCCCCEEEECCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]