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The map label for this gene is fabG [H]

Identifier: 108763921

GI number: 108763921

Start: 258083

End: 258829

Strand: Reverse

Name: fabG [H]

Synonym: MXAN_0211

Alternate gene names: 108763921

Gene position: 258829-258083 (Counterclockwise)

Preceding gene: 108759824

Following gene: 108759707

Centisome position: 2.83

GC content: 68.54

Gene sequence:

>747_bases
ATGCAGCTCAAGGACCTGAAGATCATCGTCACGGGCGGCGCCCAGGGCATGGGCGCTCACTTCGCGCAGCGCCTGCACGA
GGCGGGCGCCCAGGTGGCCGTGGGTGACGTGGCCGAGGAGCGCCTCGCCGCGCTGCCCGCCGGCATCCACCGCCGCAAGC
TGGACGTGTCCTCCGAGGAGGACATCGTCTCCTTCGTGAACTGGGCGCAGGGCGCCATGGGCGGCCTCAACGGGCTCATC
AACAACGCGGGCATCCTCCGTGACGCGCTGCTGGTGAAGAAGGACCGGACCACCGGCGAGGTGAAGAAGCTGTCCACCGC
GGACTGGAACGCCGTCATCGGCGTCAACCTCACGGGCGCCACGCTGATGGTGCGCGAGGTGGTGGCGAAGGTCGCCGAGT
CCGGCCAGAAGGGCGGCGTGGTCGTCAACATGTCGTCCATTGCCCGCCACGGCAACCGCGGTCAGTCCAACTACGTGTCC
GCGAAGGCGGCACTGGCGGCCAACACCGTCACCTGGTCGCGCGAGTTCAGCCCCTTCGGCGTGCGCGTGGGCGCGGTGGC
CCCGGGCATGATTGAGACGCCGATGACGCAGGGCATGAACCAGAAGGCCCGCGACGCGCTGGTCTCCAACATCCCCGTGG
GCCGCATCGGCGTGCCCGAGGACATCTGGCTCGCCGTGAAGTTCATCCTGGAGTGCGACTACTTCAACGGCCGCACCATC
GACGTGGACGGCGGCCTCAACTTCTGA

Upstream 100 bases:

>100_bases
AAGATTGATTCAGGTTTCAACTCGCTCGCCGCTGGCCAGCGCGGTCGGGGTTTCGTACCCTGCGCGGCATTTCGTACCAC
CCCACCTGCCGGAGAGACAC

Downstream 100 bases:

>100_bases
GTCCCCTCCTCCGGGCGGCACGGCACCGTGTCGCCTGGAGGTTCCGCTGGGACGCCGCGCTTCACCGCCGGCTGGCGTCA
CTGAGGCGCAGGTCCCTCAG

Product: short chain dehydrogenase/reductase family oxidoreductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MQLKDLKIIVTGGAQGMGAHFAQRLHEAGAQVAVGDVAEERLAALPAGIHRRKLDVSSEEDIVSFVNWAQGAMGGLNGLI
NNAGILRDALLVKKDRTTGEVKKLSTADWNAVIGVNLTGATLMVREVVAKVAESGQKGGVVVNMSSIARHGNRGQSNYVS
AKAALAANTVTWSREFSPFGVRVGAVAPGMIETPMTQGMNQKARDALVSNIPVGRIGVPEDIWLAVKFILECDYFNGRTI
DVDGGLNF

Sequences:

>Translated_248_residues
MQLKDLKIIVTGGAQGMGAHFAQRLHEAGAQVAVGDVAEERLAALPAGIHRRKLDVSSEEDIVSFVNWAQGAMGGLNGLI
NNAGILRDALLVKKDRTTGEVKKLSTADWNAVIGVNLTGATLMVREVVAKVAESGQKGGVVVNMSSIARHGNRGQSNYVS
AKAALAANTVTWSREFSPFGVRVGAVAPGMIETPMTQGMNQKARDALVSNIPVGRIGVPEDIWLAVKFILECDYFNGRTI
DVDGGLNF
>Mature_248_residues
MQLKDLKIIVTGGAQGMGAHFAQRLHEAGAQVAVGDVAEERLAALPAGIHRRKLDVSSEEDIVSFVNWAQGAMGGLNGLI
NNAGILRDALLVKKDRTTGEVKKLSTADWNAVIGVNLTGATLMVREVVAKVAESGQKGGVVVNMSSIARHGNRGQSNYVS
AKAALAANTVTWSREFSPFGVRVGAVAPGMIETPMTQGMNQKARDALVSNIPVGRIGVPEDIWLAVKFILECDYFNGRTI
DVDGGLNF

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=263, Percent_Identity=33.4600760456274, Blast_Score=114, Evalue=7e-26,
Organism=Homo sapiens, GI40254992, Length=252, Percent_Identity=31.7460317460317, Blast_Score=107, Evalue=9e-24,
Organism=Homo sapiens, GI4758504, Length=254, Percent_Identity=29.1338582677165, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI19923817, Length=255, Percent_Identity=28.2352941176471, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI83715985, Length=254, Percent_Identity=26.7716535433071, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI32483357, Length=249, Percent_Identity=28.5140562248996, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI66933014, Length=229, Percent_Identity=28.3842794759825, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI109715829, Length=241, Percent_Identity=26.1410788381743, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI7705925, Length=248, Percent_Identity=28.6290322580645, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1787335, Length=245, Percent_Identity=31.4285714285714, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI2367175, Length=251, Percent_Identity=32.6693227091633, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1790717, Length=251, Percent_Identity=27.4900398406374, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1789208, Length=249, Percent_Identity=27.3092369477912, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI87082160, Length=256, Percent_Identity=27.734375, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1786812, Length=258, Percent_Identity=27.906976744186, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI87082100, Length=255, Percent_Identity=25.0980392156863, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1788459, Length=177, Percent_Identity=27.683615819209, Blast_Score=64, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17555706, Length=246, Percent_Identity=34.5528455284553, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17538182, Length=256, Percent_Identity=34.375, Blast_Score=116, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI25147288, Length=249, Percent_Identity=31.3253012048193, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17562904, Length=267, Percent_Identity=29.2134831460674, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17560676, Length=257, Percent_Identity=24.5136186770428, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17561402, Length=253, Percent_Identity=26.0869565217391, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17560150, Length=265, Percent_Identity=29.0566037735849, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17559104, Length=261, Percent_Identity=26.0536398467433, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562990, Length=262, Percent_Identity=29.7709923664122, Blast_Score=70, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17551412, Length=265, Percent_Identity=28.6792452830189, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17538480, Length=265, Percent_Identity=27.9245283018868, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17560332, Length=272, Percent_Identity=27.5735294117647, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17538486, Length=270, Percent_Identity=26.6666666666667, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17568967, Length=208, Percent_Identity=26.9230769230769, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI115534694, Length=256, Percent_Identity=25, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24639444, Length=255, Percent_Identity=32.156862745098, Blast_Score=117, Evalue=6e-27,
Organism=Drosophila melanogaster, GI17737361, Length=254, Percent_Identity=31.496062992126, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI21355319, Length=250, Percent_Identity=29.2, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI23397609, Length=265, Percent_Identity=29.811320754717, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21357041, Length=262, Percent_Identity=28.2442748091603, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24641388, Length=239, Percent_Identity=27.6150627615063, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28571526, Length=262, Percent_Identity=27.4809160305344, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24643142, Length=249, Percent_Identity=26.5060240963855, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24648693, Length=201, Percent_Identity=27.363184079602, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21355889, Length=201, Percent_Identity=27.363184079602, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI281364494, Length=202, Percent_Identity=29.7029702970297, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 26263; Mature: 26263

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLKDLKIIVTGGAQGMGAHFAQRLHEAGAQVAVGDVAEERLAALPAGIHRRKLDVSSEE
CCCCEEEEEEECCCCCHHHHHHHHHHHCCCCEEEHHHHHHHHHHCCCCHHHHCCCCCCHH
DIVSFVNWAQGAMGGLNGLINNAGILRDALLVKKDRTTGEVKKLSTADWNAVIGVNLTGA
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHCCCCCCCEEEEEECCCH
TLMVREVVAKVAESGQKGGVVVNMSSIARHGNRGQSNYVSAKAALAANTVTWSREFSPFG
HHHHHHHHHHHHHCCCCCCEEEEHHHHHHCCCCCCCHHHHHHHHHHHCEEEECCCCCCCC
VRVGAVAPGMIETPMTQGMNQKARDALVSNIPVGRIGVPEDIWLAVKFILECDYFNGRTI
EEECCCCCCCCCCHHHCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEE
DVDGGLNF
EECCCCCC
>Mature Secondary Structure
MQLKDLKIIVTGGAQGMGAHFAQRLHEAGAQVAVGDVAEERLAALPAGIHRRKLDVSSEE
CCCCEEEEEEECCCCCHHHHHHHHHHHCCCCEEEHHHHHHHHHHCCCCHHHHCCCCCCHH
DIVSFVNWAQGAMGGLNGLINNAGILRDALLVKKDRTTGEVKKLSTADWNAVIGVNLTGA
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHCCCCCCCEEEEEECCCH
TLMVREVVAKVAESGQKGGVVVNMSSIARHGNRGQSNYVSAKAALAANTVTWSREFSPFG
HHHHHHHHHHHHHCCCCCCEEEEHHHHHHCCCCCCCHHHHHHHHHHHCEEEECCCCCCCC
VRVGAVAPGMIETPMTQGMNQKARDALVSNIPVGRIGVPEDIWLAVKFILECDYFNGRTI
EEECCCCCCCCCCHHHCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEE
DVDGGLNF
EECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]