Click here to switch to the map view.

The map label for this gene is slt [H]

Identifier: 108763880

GI number: 108763880

Start: 4941959

End: 4944094

Strand: Direct

Name: slt [H]

Synonym: MXAN_4034

Alternate gene names: 108763880

Gene position: 4941959-4944094 (Clockwise)

Preceding gene: 108759914

Following gene: 108761884

Centisome position: 54.07

GC content: 71.35

Gene sequence:

>2136_bases
ATGAGTTGGAGTGGGTGGGTTGCGGGGGTGGTTGCGGGGATGTCGCTGGGACAATCCCCCACGGCGCTGGAGGCCGTCCG
CCTCCACAAGCCGGATGCGGCCGCCCTGGCGCGCGCGGAGCTGACGGCCTGCGCCGCGAAGAAGTGCGACGACGTGGGAC
GGCTGGCGCTGCTCGCGGGGACGCTCGCCCTCTCTGACGGTCAGGCCGCCGAGGCAAGGGAACTGCTGGCTGCCTGGCCC
GCCCCTCCACTGCTGGCGCCGTACCACGCCTTCTACCTGGGCCAGGCCCGCTTCTACGCCGGGGACGCCGCGGGCGCGGC
CGAGGACTTCGCGCGAGTGCTGGAATCCAAGGCACCCGCGGAACTCGCGGCTCGTGCCCGAGCGCGGCTGGGTGAGTCAC
TGCTCAAGGCAGGCAAGCCCCAGGACGCGGCCCAGGTACTGGAGGCCGCCGCGAAGGCGTCTCCCACCGTGGAGCTGCTC
TATCAGCGTGCCTTGGCGCGAGGCGGCTCCGGAAACCGCGCTGGGCAGCGCGCCGACATGATGACGGTGGCGCTGCGCTT
CCCCACCCACCCCTACGGCAATGAGGCCATGGCGTGGCTGACGGAGGGCAGCACGCCCCCTGTGAAGCTGGGCTACACCG
AGCGCACCACCCGCGCGGACCGCTTCCTGGACGCGGGCGCGACGCAGCGCGGACTCGACGAACTGGCGACGCTGGACAAG
GTGAAGCTCGACAAGGAGCAGGCAGCCCGCGTGGCGCTGCTGCGCGCGAGGGCCTGGTTCGCGCTGGGGCGGACGGAGGA
TGCGGAGAAGGCGCTCGCGCTGGCGCGCAAGGGCCCCGCCGCCGTCGCCGCTCAGGCGGACCTGCTGGTGGCTCGGCGCG
CGCTCAAGTCCGACGACAACGCCAAGGCCCGAACGCTGATGGCGGCCCTGGACAAGAAGTACCCCTCGCAGCCCGCGGGT
GATGAAGGCGCCTTCTTCGCGGGCTGGTTGGATTTGCAGGCCGGGCGCTTCGCGGACGCGGTGCAGGCCTTCACGGCTTT
CGAAACGCGTTATCCGCGCTCACGCCGGCGCGACGAGGGCATGTGGTTCCGCGCGCTGGCCCACCTGCGTCAGGAGGAGT
ACGCGAAGGCCCGCGCCGCACTGGACGCGTTCCTGACCGCCTACCCCAAGAGCAACATGGGACCGCAGGCGCGCTACTGG
ATGGCGCGCAGCCGCGAGCTGGACGGCGCGAAGGCAGACACGTTGGGCCCCGCGTACGAGGCCGTCATCACCTCGGCGCC
CGCGTCCTTCTACGCGCTGATGGCCAACGAGCGGCTCAAGGCGCTGAGCCTGAAGACGCCCGCACACTTCCCACAGCCGC
CGCAGGTGCTGCAGCTTCCCCGCCCTCCCGAGCTGGAGCTGGCGGTGGAGCTGACGCGCGCGGGCTTGTTCCGTGACGCG
ACGGAGGAGGTGGAAGCCCACGCGGCGCGGCTGCGCTCGGCGGACCAGGCCCTGCCCTTCGCGCACGCGCTGCTGGGACT
GGGTGAGTACGGCCACGCCCACGCGGTGGCGGCGCGCCACCTGTGGGGACGGGCCTTCGGCGCGCGCGCTCCGGAGGCCC
TGGCGCCCTTCTATCCTCGCGCCTTCGCCACCGCGGTGGAGGGAGCGGCGACGCAGCACCAGGTGGACCCCTACCTGGTG
TGGGCCATCATGCGGCGGGAGAGCGCCTTCCGGCCGGAGGTGATGAGCATCGCCGATGCACGAGGGCTGATGCAGATCAT
CCCCAAGACGGCGAACGCCATCGCGGAGAAGCTGAAGGAGCCCGTCCCCGCGCCCGCGGACCTCTTCTCCCCCGAGCGGA
ACATCCGCTATGGCGCCTGGTATCTGTCCCGGCTGATGGAGCGCTTTGGACACCCGGTGCTCGCGGCGGCCGCGTACAAC
GCGGGCCCAGGCTCGGCGGCGAAGTGGGTCCAGGAGCGGAGCTCGCTGCCACTGGACCTCTTCGTGGAGACCATCCCCTT
CAAGGAAACGCGCGGCTACGTGAAGCAGGTGGTGGCGGACCTGTTCCTCTACCACTCCTTCTACGGCGACGGCACGGGGG
CGCTGAAGCTGCCACTACAGGTGCCCGCGCCGTCGAAGGAAGGTGTCAGCTTCTAG

Upstream 100 bases:

>100_bases
GCGCCCGCTGTCAAACCACCCTCCCTGCGGGGCAAGGGGAATGATCGGTGTGTGCGTCTCGTTGGCAGGCCGCAAAGCCG
CGTCGTGAAAGGAAGACCAC

Downstream 100 bases:

>100_bases
GCTCCGACTGGGGCGCCAGGCCCGCGAGACGACGCGCGGGCGCGCGCCGAGCGTCAATCCCGGTCTGGCGCGCCCAGGGG
AAAGAGCGGCCGGAAACGCC

Product: transglycosylase SLT domain-containing protein

Products: 1,6-Anhydrobond [C]

Alternate protein names: Peptidoglycan lytic exotransglycosylase [H]

Number of amino acids: Translated: 711; Mature: 710

Protein sequence:

>711_residues
MSWSGWVAGVVAGMSLGQSPTALEAVRLHKPDAAALARAELTACAAKKCDDVGRLALLAGTLALSDGQAAEARELLAAWP
APPLLAPYHAFYLGQARFYAGDAAGAAEDFARVLESKAPAELAARARARLGESLLKAGKPQDAAQVLEAAAKASPTVELL
YQRALARGGSGNRAGQRADMMTVALRFPTHPYGNEAMAWLTEGSTPPVKLGYTERTTRADRFLDAGATQRGLDELATLDK
VKLDKEQAARVALLRARAWFALGRTEDAEKALALARKGPAAVAAQADLLVARRALKSDDNAKARTLMAALDKKYPSQPAG
DEGAFFAGWLDLQAGRFADAVQAFTAFETRYPRSRRRDEGMWFRALAHLRQEEYAKARAALDAFLTAYPKSNMGPQARYW
MARSRELDGAKADTLGPAYEAVITSAPASFYALMANERLKALSLKTPAHFPQPPQVLQLPRPPELELAVELTRAGLFRDA
TEEVEAHAARLRSADQALPFAHALLGLGEYGHAHAVAARHLWGRAFGARAPEALAPFYPRAFATAVEGAATQHQVDPYLV
WAIMRRESAFRPEVMSIADARGLMQIIPKTANAIAEKLKEPVPAPADLFSPERNIRYGAWYLSRLMERFGHPVLAAAAYN
AGPGSAAKWVQERSSLPLDLFVETIPFKETRGYVKQVVADLFLYHSFYGDGTGALKLPLQVPAPSKEGVSF

Sequences:

>Translated_711_residues
MSWSGWVAGVVAGMSLGQSPTALEAVRLHKPDAAALARAELTACAAKKCDDVGRLALLAGTLALSDGQAAEARELLAAWP
APPLLAPYHAFYLGQARFYAGDAAGAAEDFARVLESKAPAELAARARARLGESLLKAGKPQDAAQVLEAAAKASPTVELL
YQRALARGGSGNRAGQRADMMTVALRFPTHPYGNEAMAWLTEGSTPPVKLGYTERTTRADRFLDAGATQRGLDELATLDK
VKLDKEQAARVALLRARAWFALGRTEDAEKALALARKGPAAVAAQADLLVARRALKSDDNAKARTLMAALDKKYPSQPAG
DEGAFFAGWLDLQAGRFADAVQAFTAFETRYPRSRRRDEGMWFRALAHLRQEEYAKARAALDAFLTAYPKSNMGPQARYW
MARSRELDGAKADTLGPAYEAVITSAPASFYALMANERLKALSLKTPAHFPQPPQVLQLPRPPELELAVELTRAGLFRDA
TEEVEAHAARLRSADQALPFAHALLGLGEYGHAHAVAARHLWGRAFGARAPEALAPFYPRAFATAVEGAATQHQVDPYLV
WAIMRRESAFRPEVMSIADARGLMQIIPKTANAIAEKLKEPVPAPADLFSPERNIRYGAWYLSRLMERFGHPVLAAAAYN
AGPGSAAKWVQERSSLPLDLFVETIPFKETRGYVKQVVADLFLYHSFYGDGTGALKLPLQVPAPSKEGVSF
>Mature_710_residues
SWSGWVAGVVAGMSLGQSPTALEAVRLHKPDAAALARAELTACAAKKCDDVGRLALLAGTLALSDGQAAEARELLAAWPA
PPLLAPYHAFYLGQARFYAGDAAGAAEDFARVLESKAPAELAARARARLGESLLKAGKPQDAAQVLEAAAKASPTVELLY
QRALARGGSGNRAGQRADMMTVALRFPTHPYGNEAMAWLTEGSTPPVKLGYTERTTRADRFLDAGATQRGLDELATLDKV
KLDKEQAARVALLRARAWFALGRTEDAEKALALARKGPAAVAAQADLLVARRALKSDDNAKARTLMAALDKKYPSQPAGD
EGAFFAGWLDLQAGRFADAVQAFTAFETRYPRSRRRDEGMWFRALAHLRQEEYAKARAALDAFLTAYPKSNMGPQARYWM
ARSRELDGAKADTLGPAYEAVITSAPASFYALMANERLKALSLKTPAHFPQPPQVLQLPRPPELELAVELTRAGLFRDAT
EEVEAHAARLRSADQALPFAHALLGLGEYGHAHAVAARHLWGRAFGARAPEALAPFYPRAFATAVEGAATQHQVDPYLVW
AIMRRESAFRPEVMSIADARGLMQIIPKTANAIAEKLKEPVPAPADLFSPERNIRYGAWYLSRLMERFGHPVLAAAAYNA
GPGSAAKWVQERSSLPLDLFVETIPFKETRGYVKQVVADLFLYHSFYGDGTGALKLPLQVPAPSKEGVSF

Specific function: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division [H]

COG id: COG0741

COG function: function code M; Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transglycosylase slt family [H]

Homologues:

Organism=Escherichia coli, GI87082441, Length=267, Percent_Identity=31.4606741573034, Blast_Score=102, Evalue=9e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011989
- InterPro:   IPR016026
- InterPro:   IPR008258
- InterPro:   IPR012289
- InterPro:   IPR008939
- InterPro:   IPR000189 [H]

Pfam domain/function: PF01464 SLT [H]

EC number: 3.2.1.- [C]

Molecular weight: Translated: 76856; Mature: 76725

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: PS50293 TPR_REGION ; PS00922 TRANSGLYCOSYLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWSGWVAGVVAGMSLGQSPTALEAVRLHKPDAAALARAELTACAAKKCDDVGRLALLAG
CCCCHHHHHHHHHHHCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLALSDGQAAEARELLAAWPAPPLLAPYHAFYLGQARFYAGDAAGAAEDFARVLESKAPA
HHHCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHCCHHEECCCCCCHHHHHHHHHHCCCCH
ELAARARARLGESLLKAGKPQDAAQVLEAAAKASPTVELLYQRALARGGSGNRAGQRADM
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCHHHH
MTVALRFPTHPYGNEAMAWLTEGSTPPVKLGYTERTTRADRFLDAGATQRGLDELATLDK
EEEEEECCCCCCCCCCEEEEECCCCCCEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHH
VKLDKEQAARVALLRARAWFALGRTEDAEKALALARKGPAAVAAQADLLVARRALKSDDN
HHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCC
AKARTLMAALDKKYPSQPAGDEGAFFAGWLDLQAGRFADAVQAFTAFETRYPRSRRRDEG
HHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCHHHCCCCC
MWFRALAHLRQEEYAKARAALDAFLTAYPKSNMGPQARYWMARSRELDGAKADTLGPAYE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHH
AVITSAPASFYALMANERLKALSLKTPAHFPQPPQVLQLPRPPELELAVELTRAGLFRDA
HHHHCCCHHHHHHHHHCHHHHEECCCCCCCCCCCHHEECCCCCCCHHHHHHHHHHHHHHH
TEEVEAHAARLRSADQALPFAHALLGLGEYGHAHAVAARHLWGRAFGARAPEALAPFYPR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHCCCCHH
AFATAVEGAATQHQVDPYLVWAIMRRESAFRPEVMSIADARGLMQIIPKTANAIAEKLKE
HHHHHHHCCCHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PVPAPADLFSPERNIRYGAWYLSRLMERFGHPVLAAAAYNAGPGSAAKWVQERSSLPLDL
CCCCCHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHCCCHHH
FVETIPFKETRGYVKQVVADLFLYHSFYGDGTGALKLPLQVPAPSKEGVSF
HHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCC
>Mature Secondary Structure 
SWSGWVAGVVAGMSLGQSPTALEAVRLHKPDAAALARAELTACAAKKCDDVGRLALLAG
CCCHHHHHHHHHHHCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLALSDGQAAEARELLAAWPAPPLLAPYHAFYLGQARFYAGDAAGAAEDFARVLESKAPA
HHHCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHCCHHEECCCCCCHHHHHHHHHHCCCCH
ELAARARARLGESLLKAGKPQDAAQVLEAAAKASPTVELLYQRALARGGSGNRAGQRADM
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCHHHH
MTVALRFPTHPYGNEAMAWLTEGSTPPVKLGYTERTTRADRFLDAGATQRGLDELATLDK
EEEEEECCCCCCCCCCEEEEECCCCCCEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHH
VKLDKEQAARVALLRARAWFALGRTEDAEKALALARKGPAAVAAQADLLVARRALKSDDN
HHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCC
AKARTLMAALDKKYPSQPAGDEGAFFAGWLDLQAGRFADAVQAFTAFETRYPRSRRRDEG
HHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCHHHCCCCC
MWFRALAHLRQEEYAKARAALDAFLTAYPKSNMGPQARYWMARSRELDGAKADTLGPAYE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHH
AVITSAPASFYALMANERLKALSLKTPAHFPQPPQVLQLPRPPELELAVELTRAGLFRDA
HHHHCCCHHHHHHHHHCHHHHEECCCCCCCCCCCHHEECCCCCCCHHHHHHHHHHHHHHH
TEEVEAHAARLRSADQALPFAHALLGLGEYGHAHAVAARHLWGRAFGARAPEALAPFYPR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHCCCCHH
AFATAVEGAATQHQVDPYLVWAIMRRESAFRPEVMSIADARGLMQIIPKTANAIAEKLKE
HHHHHHHCCCHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PVPAPADLFSPERNIRYGAWYLSRLMERFGHPVLAAAAYNAGPGSAAKWVQERSSLPLDL
CCCCCHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHCCCHHH
FVETIPFKETRGYVKQVVADLFLYHSFYGDGTGALKLPLQVPAPSKEGVSF
HHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond Between N-Acetylmuramic Acid And N-Acetylglucosamine Residues, Thereby Conserving The Energy In A Newly Synthesized 1,6-Anhydrobond In The Muramic Acid Residue. [C]

General reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]