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The map label for this gene is acoC [H]

Identifier: 108763852

GI number: 108763852

Start: 6242026

End: 6242784

Strand: Reverse

Name: acoC [H]

Synonym: MXAN_4991

Alternate gene names: 108763852

Gene position: 6242784-6242026 (Counterclockwise)

Preceding gene: 108760898

Following gene: 108759208

Centisome position: 68.3

GC content: 71.81

Gene sequence:

>759_bases
ATGATGGGGTCCACGGGAATGCTGAATGTCGACGATGGGGGCGTGGGTGGACTGCCGGTGGTGTTCGTCCATTCCAGCGC
CGGCAACACCACGCACTGGGCCGCGCAGCTGTCGTACCTGCGCGAGCGCCGCCGGGCCTTGGCACTGGACCTGCGTGGCC
ACGGGAAGTCCGAGCTGCCACGGGACGGCGGCTTCGCCGTGGAGGACTTCGCGCGGGACGTGGGGACGGTGGTGGATGGG
CTGGGGCTTCAGCGCTTCGTGCTGGTGGGGCACAGCCTGGGCGGGGCCGTCTGCGTGGCCTACGCGGGGGCGCAGCCGGA
CCGCGTCGCGGGGTTGTTCCTCCTCGACCCGGCCTCGGATGGACGCTCGATGCCAGCGGAGCAGGCCCGGGGCTTGATGG
CGGTGCTGGCGACCGAGGCCTGGAGCGCGGTGGTGGAGGAGGCCTGGTCCCCCATGTTGGCGCCGTCCCGGCCGGAGGTG
CGCGAGCGCATTCTCTCCGAGATGCGCGCCACGTCCCAAGAGGGCGTCCGGGGCGGACTGGGGGCCCTGCTGGACTTCGA
CCCCGTGACGCCGCTGCGGCGCTACTCGGGGCCGCGTCTGTCGGTCGTGACGGCCTTCAATGAGGAACCGGGCTCGTATC
ACCACCTGGTGCCGGAGCTGCCGCACGCGAAGGTGGAGGGCACGGGGCACTGGGTGCAGCTCGACGCTCCGGACGAGGTG
AACCGGCTGCTGGACGGCTTTCTCGCCACGGTGCGCTGA

Upstream 100 bases:

>100_bases
CGACTCGTGCCATTGCTGACAGTTTCTGTCAGGGATGGGCCGTACTCCACAAGCATCACGTCGCGCACGACTGCGCGCTT
CGAGGCCAGAGGAGGCCGTC

Downstream 100 bases:

>100_bases
GCGCGCGCGTTCGCCGCGCGTGTTATCTACGGCCCGTGCCCCGGCCCAAGCTGCACAGCGACGAAGCCATCCTCGACGCC
GCCATGTTCGTGTTGCTTCG

Product: alpha/beta fold family hydrolase

Products: NA

Alternate protein names: Acetoin dehydrogenase E2 component; Dihydrolipoamide acetyltransferase component of acetoin cleaving system [H]

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MMGSTGMLNVDDGGVGGLPVVFVHSSAGNTTHWAAQLSYLRERRRALALDLRGHGKSELPRDGGFAVEDFARDVGTVVDG
LGLQRFVLVGHSLGGAVCVAYAGAQPDRVAGLFLLDPASDGRSMPAEQARGLMAVLATEAWSAVVEEAWSPMLAPSRPEV
RERILSEMRATSQEGVRGGLGALLDFDPVTPLRRYSGPRLSVVTAFNEEPGSYHHLVPELPHAKVEGTGHWVQLDAPDEV
NRLLDGFLATVR

Sequences:

>Translated_252_residues
MMGSTGMLNVDDGGVGGLPVVFVHSSAGNTTHWAAQLSYLRERRRALALDLRGHGKSELPRDGGFAVEDFARDVGTVVDG
LGLQRFVLVGHSLGGAVCVAYAGAQPDRVAGLFLLDPASDGRSMPAEQARGLMAVLATEAWSAVVEEAWSPMLAPSRPEV
RERILSEMRATSQEGVRGGLGALLDFDPVTPLRRYSGPRLSVVTAFNEEPGSYHHLVPELPHAKVEGTGHWVQLDAPDEV
NRLLDGFLATVR
>Mature_252_residues
MMGSTGMLNVDDGGVGGLPVVFVHSSAGNTTHWAAQLSYLRERRRALALDLRGHGKSELPRDGGFAVEDFARDVGTVVDG
LGLQRFVLVGHSLGGAVCVAYAGAQPDRVAGLFLLDPASDGRSMPAEQARGLMAVLATEAWSAVVEEAWSPMLAPSRPEV
RERILSEMRATSQEGVRGGLGALLDFDPVTPLRRYSGPRLSVVTAFNEEPGSYHHLVPELPHAKVEGTGHWVQLDAPDEV
NRLLDGFLATVR

Specific function: 3-hydroxyphenylpropionate degradation. [C]

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 lipoyl-binding domain [H]

Homologues:

Organism=Homo sapiens, GI50658087, Length=102, Percent_Identity=36.2745098039216, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI23200012, Length=265, Percent_Identity=28.3018867924528, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI23200008, Length=265, Percent_Identity=28.3018867924528, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003016
- InterPro:   IPR000073
- InterPro:   IPR000089
- InterPro:   IPR011053 [H]

Pfam domain/function: PF00561 Abhydrolase_1; PF00364 Biotin_lipoyl [H]

EC number: =2.3.1.12 [H]

Molecular weight: Translated: 26942; Mature: 26942

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMGSTGMLNVDDGGVGGLPVVFVHSSAGNTTHWAAQLSYLRERRRALALDLRGHGKSELP
CCCCCCEEECCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHEEEEECCCCCCCCC
RDGGFAVEDFARDVGTVVDGLGLQRFVLVGHSLGGAVCVAYAGAQPDRVAGLFLLDPASD
CCCCCCHHHHHHHHHHHHHCCCHHHHHHECCCCCCEEEEEECCCCCCCEEEEEEECCCCC
GRSMPAEQARGLMAVLATEAWSAVVEEAWSPMLAPSRPEVRERILSEMRATSQEGVRGGL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCH
GALLDFDPVTPLRRYSGPRLSVVTAFNEEPGSYHHLVPELPHAKVEGTGHWVQLDAPDEV
HHHCCCCCCCHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCEECCCCCEEEECCCHHH
NRLLDGFLATVR
HHHHHHHHHHCC
>Mature Secondary Structure
MMGSTGMLNVDDGGVGGLPVVFVHSSAGNTTHWAAQLSYLRERRRALALDLRGHGKSELP
CCCCCCEEECCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHEEEEECCCCCCCCC
RDGGFAVEDFARDVGTVVDGLGLQRFVLVGHSLGGAVCVAYAGAQPDRVAGLFLLDPASD
CCCCCCHHHHHHHHHHHHHCCCHHHHHHECCCCCCEEEEEECCCCCCCEEEEEEECCCCC
GRSMPAEQARGLMAVLATEAWSAVVEEAWSPMLAPSRPEVRERILSEMRATSQEGVRGGL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCH
GALLDFDPVTPLRRYSGPRLSVVTAFNEEPGSYHHLVPELPHAKVEGTGHWVQLDAPDEV
HHHCCCCCCCHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCEECCCCCEEEECCCHHH
NRLLDGFLATVR
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7813883 [H]