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The map label for this gene is rsmB [H]

Identifier: 108763815

GI number: 108763815

Start: 2238920

End: 2240203

Strand: Direct

Name: rsmB [H]

Synonym: MXAN_1909

Alternate gene names: 108763815

Gene position: 2238920-2240203 (Clockwise)

Preceding gene: 108760934

Following gene: 108760434

Centisome position: 24.5

GC content: 73.29

Gene sequence:

>1284_bases
ATGGTGCCCGCTCTGTCAACAGTCCCTTTTGATCCGCTCTCCCGGCTTCACCTCCAGCCCTGGTCCGCACTCGCCGGCCT
GGGCCCCGTGGCGGCCGATGCCATCGCCCAGGTGCTCGCCGGCTCCGCCGCTGAGCGGGTGCTCGACCGTACTCTCCGCG
ACCGTCGCTCCCTGACCCGAGAGCAGCGCCTGGCCCTCAAGGAGGCCGTCTTCAACGTCGGGCTCTGGCGGCGCCGCCTC
GGGTTCCTCCTGGGCCGCGAGGATGCCGCTCCTCTCTTCCTGCTCCATGCCCTGATGCACGGCCTCGCGGGCGTCCCGGC
TGTGGAGTCCGCCGCCCTCGCCGGGCTCGGGGATGGGGCGCCGCCCCCGTTGGTTTCGGCGCCGCCCCCCACGCTCGCGC
TCCGCGCCTCCCTGCCGGACTGGCTCGCCGACCATTTCGCCCGGGAGTTCGGTCCCGAGGCCGACGACTTCTGCGCCCAC
CTGAACGTCCCCGGGCCCATCACCCTCCGGGCCAACGTCCTGCGCACCTCGCGGGAGGCCCTTGCCGAGCGGCTTCGCTC
CGAGGGCGTCGAGACGCGCCCGGGGCCCTGGAGCCCGCTGGCGCTCCATATCGAGGGTCCCCGGCCCAACCTCTATGGGC
TCCGTTCCCTCCAGGAGGGGCTGTTCGAAGTCCAGGACGAGGGCAGCCAGCTCCTGGGGCTCCTCGTGGAGGCCCGGCCC
GGGGAGACGGTGCTGGACCTCTGTGCCGGCGCGGGCGGCAAGACGCTCCAACTGGGCGCGGACATGAAGGACTCGGGGCG
GCTCCTGGCCTATGACCCGGACCCCGAGCGGCTCGACCGGCTCCTCCAGCGCTCCTCCCGGGCCCACCTCACCCGAGTCC
AGGTGCTCCGGAGCCTTCCCGAAAGCCTGGACGCGGACCGGGTGCTCGTGGACGCGCCGTGCTCGGAGCTGGGCTCCCTG
CGCCGGGGCCCCGACCAGCGCTTCCGCATCCAGCCGGAGGTGCTCACCCGGTTTCCGGCGCTCCAGCAGGACATTCTCCA
GCGTGGGGCACGCCTGGTGCGGCCCGGCGGGCGGCTCGTTTACGCCACCTGCACCGTCAACCGCGCGGAGAATGAGGACG
TCGTCGCCGCCTTCCTGGCTTCGCGCCCGGACTTCCGCCTCGTGCGGCCCGGGGCGGGGTGGCTTTCCGACGCGTGTCTC
CGCGACGGATTCCTCTTCGTCGCGCCCCACCGGCATGGCACGGACGCCTTCTTCGCGGCGGTCCTGGAGCGGACGGCAGG
GTAG

Upstream 100 bases:

>100_bases
GGACCTAGTGATTAACAGTCACCCGCTCTACCGGCTGAGCTATCGGGGAATATGTCCTCACGGCGGAACCGCGTTGCCGT
GATGAGGCGCTTTCTAGAGA

Downstream 100 bases:

>100_bases
GGGCAGGGGCGACAGGCGGTCGCAGTGTCCGTGTCCCGACGGACGGGGGAACTCAACGCTTCGCCCGCCCGGGCCTCGAA
TCACCGTGCCCCTCGGGCCC

Product: RsmB/NOP family methyltransferase

Products: NA

Alternate protein names: rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MVPALSTVPFDPLSRLHLQPWSALAGLGPVAADAIAQVLAGSAAERVLDRTLRDRRSLTREQRLALKEAVFNVGLWRRRL
GFLLGREDAAPLFLLHALMHGLAGVPAVESAALAGLGDGAPPPLVSAPPPTLALRASLPDWLADHFAREFGPEADDFCAH
LNVPGPITLRANVLRTSREALAERLRSEGVETRPGPWSPLALHIEGPRPNLYGLRSLQEGLFEVQDEGSQLLGLLVEARP
GETVLDLCAGAGGKTLQLGADMKDSGRLLAYDPDPERLDRLLQRSSRAHLTRVQVLRSLPESLDADRVLVDAPCSELGSL
RRGPDQRFRIQPEVLTRFPALQQDILQRGARLVRPGGRLVYATCTVNRAENEDVVAAFLASRPDFRLVRPGAGWLSDACL
RDGFLFVAPHRHGTDAFFAAVLERTAG

Sequences:

>Translated_427_residues
MVPALSTVPFDPLSRLHLQPWSALAGLGPVAADAIAQVLAGSAAERVLDRTLRDRRSLTREQRLALKEAVFNVGLWRRRL
GFLLGREDAAPLFLLHALMHGLAGVPAVESAALAGLGDGAPPPLVSAPPPTLALRASLPDWLADHFAREFGPEADDFCAH
LNVPGPITLRANVLRTSREALAERLRSEGVETRPGPWSPLALHIEGPRPNLYGLRSLQEGLFEVQDEGSQLLGLLVEARP
GETVLDLCAGAGGKTLQLGADMKDSGRLLAYDPDPERLDRLLQRSSRAHLTRVQVLRSLPESLDADRVLVDAPCSELGSL
RRGPDQRFRIQPEVLTRFPALQQDILQRGARLVRPGGRLVYATCTVNRAENEDVVAAFLASRPDFRLVRPGAGWLSDACL
RDGFLFVAPHRHGTDAFFAAVLERTAG
>Mature_427_residues
MVPALSTVPFDPLSRLHLQPWSALAGLGPVAADAIAQVLAGSAAERVLDRTLRDRRSLTREQRLALKEAVFNVGLWRRRL
GFLLGREDAAPLFLLHALMHGLAGVPAVESAALAGLGDGAPPPLVSAPPPTLALRASLPDWLADHFAREFGPEADDFCAH
LNVPGPITLRANVLRTSREALAERLRSEGVETRPGPWSPLALHIEGPRPNLYGLRSLQEGLFEVQDEGSQLLGLLVEARP
GETVLDLCAGAGGKTLQLGADMKDSGRLLAYDPDPERLDRLLQRSSRAHLTRVQVLRSLPESLDADRVLVDAPCSELGSL
RRGPDQRFRIQPEVLTRFPALQQDILQRGARLVRPGGRLVYATCTVNRAENEDVVAAFLASRPDFRLVRPGAGWLSDACL
RDGFLFVAPHRHGTDAFFAAVLERTAG

Specific function: Unknown

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=290, Percent_Identity=31.0344827586207, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI76150623, Length=290, Percent_Identity=31.0344827586207, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI32698918, Length=184, Percent_Identity=30.9782608695652, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI301336155, Length=285, Percent_Identity=29.1228070175439, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI39995082, Length=312, Percent_Identity=28.2051282051282, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI11545785, Length=166, Percent_Identity=34.9397590361446, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI23199998, Length=222, Percent_Identity=31.5315315315315, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI270288818, Length=227, Percent_Identity=30.8370044052863, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI8922322, Length=222, Percent_Identity=31.0810810810811, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI270288816, Length=222, Percent_Identity=31.5315315315315, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI87081985, Length=290, Percent_Identity=31.3793103448276, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI2367212, Length=328, Percent_Identity=29.2682926829268, Blast_Score=106, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17536757, Length=308, Percent_Identity=28.2467532467532, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI25143471, Length=163, Percent_Identity=32.5153374233129, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6324268, Length=307, Percent_Identity=29.9674267100977, Blast_Score=114, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6319447, Length=187, Percent_Identity=33.6898395721925, Blast_Score=84, Evalue=4e-17,
Organism=Drosophila melanogaster, GI22024126, Length=284, Percent_Identity=26.4084507042254, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24668781, Length=200, Percent_Identity=32, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI21356513, Length=181, Percent_Identity=32.5966850828729, Blast_Score=86, Evalue=7e-17,
Organism=Drosophila melanogaster, GI21355201, Length=220, Percent_Identity=29.5454545454545, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI19920494, Length=188, Percent_Identity=31.3829787234043, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: NA

Molecular weight: Translated: 46336; Mature: 46336

Theoretical pI: Translated: 7.27; Mature: 7.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVPALSTVPFDPLSRLHLQPWSALAGLGPVAADAIAQVLAGSAAERVLDRTLRDRRSLTR
CCCCCCCCCCCHHHHHHCCCHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH
EQRLALKEAVFNVGLWRRRLGFLLGREDAAPLFLLHALMHGLAGVPAVESAALAGLGDGA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCC
PPPLVSAPPPTLALRASLPDWLADHFAREFGPEADDFCAHLNVPGPITLRANVLRTSREA
CCCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCHHHHEEECCCCCCEEEEHHHHHHHHHH
LAERLRSEGVETRPGPWSPLALHIEGPRPNLYGLRSLQEGLFEVQDEGSQLLGLLVEARP
HHHHHHHCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHCCCC
GETVLDLCAGAGGKTLQLGADMKDSGRLLAYDPDPERLDRLLQRSSRAHLTRVQVLRSLP
CHHHHHHHCCCCCCEEEECCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ESLDADRVLVDAPCSELGSLRRGPDQRFRIQPEVLTRFPALQQDILQRGARLVRPGGRLV
HHCCCCCEEEECCHHHHHHHHCCCCCCEEECHHHHHHCHHHHHHHHHCCHHEECCCCCEE
YATCTVNRAENEDVVAAFLASRPDFRLVRPGAGWLSDACLRDGFLFVAPHRHGTDAFFAA
EEEEEECCCCCCHHHHHHHHCCCCCEEECCCCCHHHHHHHHCCEEEEECCCCCHHHHHHH
VLERTAG
HHHHHCC
>Mature Secondary Structure
MVPALSTVPFDPLSRLHLQPWSALAGLGPVAADAIAQVLAGSAAERVLDRTLRDRRSLTR
CCCCCCCCCCCHHHHHHCCCHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH
EQRLALKEAVFNVGLWRRRLGFLLGREDAAPLFLLHALMHGLAGVPAVESAALAGLGDGA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCC
PPPLVSAPPPTLALRASLPDWLADHFAREFGPEADDFCAHLNVPGPITLRANVLRTSREA
CCCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCHHHHEEECCCCCCEEEEHHHHHHHHHH
LAERLRSEGVETRPGPWSPLALHIEGPRPNLYGLRSLQEGLFEVQDEGSQLLGLLVEARP
HHHHHHHCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHCCCC
GETVLDLCAGAGGKTLQLGADMKDSGRLLAYDPDPERLDRLLQRSSRAHLTRVQVLRSLP
CHHHHHHHCCCCCCEEEECCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ESLDADRVLVDAPCSELGSLRRGPDQRFRIQPEVLTRFPALQQDILQRGARLVRPGGRLV
HHCCCCCEEEECCHHHHHHHHCCCCCCEEECHHHHHHCHHHHHHHHHCCHHEECCCCCEE
YATCTVNRAENEDVVAAFLASRPDFRLVRPGAGWLSDACLRDGFLFVAPHRHGTDAFFAA
EEEEEECCCCCCHHHHHHHHCCCCCEEECCCCCHHHHHHHHCCEEEEECCCCCHHHHHHH
VLERTAG
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377; 9086272 [H]