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The map label for this gene is plsC [H]

Identifier: 108763748

GI number: 108763748

Start: 181382

End: 182230

Strand: Reverse

Name: plsC [H]

Synonym: MXAN_0147

Alternate gene names: 108763748

Gene position: 182230-181382 (Counterclockwise)

Preceding gene: 108758619

Following gene: 108757604

Centisome position: 1.99

GC content: 67.37

Gene sequence:

>849_bases
ATGGCGCGGAACAGGGTCATCGGCATGCGCCACGAAGCAGACCGGCGCCGCGCGACACCTCCAAGTACAAGCCCACCTGC
CGCGAGCCTGTGGCACACTGCGCGCGCCATTCGACTCCTCTTCTCCATCGTCTTCTGGGCGTTCCTGATGCTCTCCAGCG
CCGTGCTCTTCGTGGGCGCCGTGCTGGTCTGGCTCGTCACGTTGCCGTTCGACCGCGACGGGCGCGTCCTGCACCTGTAT
TCGTGCTTCTGGGCGCAGCTCTACTTCTACGTCAACCCGCTCTGGCACCTGGAGGTCGACGGCCGCGAACACCTGCCCTG
GCGGGGCCCGGCCGTGCTCGTGTCCAACCACGAGTCGCTCGGCGACATCCTGGTCCTCTTCGGCCTCTACCGCCCCTTCA
AGTGGGTCTCCAAGGCGTCGAACTTCAAGCTGCCGCTCATCGGCTGGAACATGCGGCTCAACCGCTATGTCCCCCTGGTG
CGCGGTGACAGGGCGAGCATCACGAAGATGCTGGCCGACTGCGAATACTGGCTGTCTCGCGGCGTGCCCATCCTCATGTT
CCCCGAAGGCACGCGCTCCTCCGACGGCGTCGTGAAGCCCTTCAAGGACGGCGCCTTCGCGTTGGCCTTGAAGCAGCGCT
GCCCCGTCATCCCCGTGGTCCTCACCGGCACCGCGCGCACCCTGCCCAAGCACGGCCTGGTGCTGGAGACCACCGCCCGC
TGCCACGTCCAGGTCATGCCCCCCGTCGACCCCAGCGCCTTCACCGACGTGGCCTCCCTGCGTGAGCACGTCCGGAATCT
CATCGTCTCGGAAAAGGCGCGCATCGAGGCGCTGACGCCCGGCGCCTGA

Upstream 100 bases:

>100_bases
CGAGACGCCTTCGCCGCCGAGGGCGCGCGGGTGCAAGCGCTGGACGCTTCCACGAGCGAACCGCCCGCGCCCGTGTCCGT
GCTGAAGACGGGCTAGCCAG

Downstream 100 bases:

>100_bases
CACATCCCTCCCGGCCCGCCCCTTTCACCGGCTCGAGAACCCAGGCAAAGATGCCCACCGGGTTCGAGGCGGGGCTCTCC
GAGGAACGCGATGCGCAAAC

Product: putative acetyltransferase

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT; Phosphatidic acid synthase; PA synthase [H]

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MARNRVIGMRHEADRRRATPPSTSPPAASLWHTARAIRLLFSIVFWAFLMLSSAVLFVGAVLVWLVTLPFDRDGRVLHLY
SCFWAQLYFYVNPLWHLEVDGREHLPWRGPAVLVSNHESLGDILVLFGLYRPFKWVSKASNFKLPLIGWNMRLNRYVPLV
RGDRASITKMLADCEYWLSRGVPILMFPEGTRSSDGVVKPFKDGAFALALKQRCPVIPVVLTGTARTLPKHGLVLETTAR
CHVQVMPPVDPSAFTDVASLREHVRNLIVSEKARIEALTPGA

Sequences:

>Translated_282_residues
MARNRVIGMRHEADRRRATPPSTSPPAASLWHTARAIRLLFSIVFWAFLMLSSAVLFVGAVLVWLVTLPFDRDGRVLHLY
SCFWAQLYFYVNPLWHLEVDGREHLPWRGPAVLVSNHESLGDILVLFGLYRPFKWVSKASNFKLPLIGWNMRLNRYVPLV
RGDRASITKMLADCEYWLSRGVPILMFPEGTRSSDGVVKPFKDGAFALALKQRCPVIPVVLTGTARTLPKHGLVLETTAR
CHVQVMPPVDPSAFTDVASLREHVRNLIVSEKARIEALTPGA
>Mature_281_residues
ARNRVIGMRHEADRRRATPPSTSPPAASLWHTARAIRLLFSIVFWAFLMLSSAVLFVGAVLVWLVTLPFDRDGRVLHLYS
CFWAQLYFYVNPLWHLEVDGREHLPWRGPAVLVSNHESLGDILVLFGLYRPFKWVSKASNFKLPLIGWNMRLNRYVPLVR
GDRASITKMLADCEYWLSRGVPILMFPEGTRSSDGVVKPFKDGAFALALKQRCPVIPVVLTGTARTLPKHGLVLETTARC
HVQVMPPVDPSAFTDVASLREHVRNLIVSEKARIEALTPGA

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the 2 position. This enzyme can utilize either acyl-CoA or acyl-ACP as the fatty acyl donor [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI5453718, Length=253, Percent_Identity=28.4584980237154, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI15100175, Length=253, Percent_Identity=28.4584980237154, Blast_Score=79, Evalue=5e-15,
Organism=Escherichia coli, GI1789395, Length=203, Percent_Identity=27.0935960591133, Blast_Score=71, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17568319, Length=234, Percent_Identity=26.0683760683761, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17564032, Length=260, Percent_Identity=26.1538461538462, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320151, Length=230, Percent_Identity=29.1304347826087, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24641614, Length=239, Percent_Identity=28.0334728033473, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24641612, Length=239, Percent_Identity=28.0334728033473, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI281364648, Length=237, Percent_Identity=27.8481012658228, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24582856, Length=237, Percent_Identity=27.8481012658228, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24582854, Length=237, Percent_Identity=27.8481012658228, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 31789; Mature: 31658

Theoretical pI: Translated: 10.56; Mature: 10.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARNRVIGMRHEADRRRATPPSTSPPAASLWHTARAIRLLFSIVFWAFLMLSSAVLFVGA
CCCCCEEECCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLVWLVTLPFDRDGRVLHLYSCFWAQLYFYVNPLWHLEVDGREHLPWRGPAVLVSNHESL
HHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCEEEEECCCHH
GDILVLFGLYRPFKWVSKASNFKLPLIGWNMRLNRYVPLVRGDRASITKMLADCEYWLSR
HHHHHHHHHHHHHHHHHCCCCCCEEEEEECEEECCCCCEEECCHHHHHHHHHHHHHHHHC
GVPILMFPEGTRSSDGVVKPFKDGAFALALKQRCPVIPVVLTGTARTLPKHGLVLETTAR
CCEEEEECCCCCCCCCCCCCCCCCCEEEEHHHCCCEEEEEEECCCHHCCCCCEEEEECCE
CHVQVMPPVDPSAFTDVASLREHVRNLIVSEKARIEALTPGA
EEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHEEEECCCC
>Mature Secondary Structure 
ARNRVIGMRHEADRRRATPPSTSPPAASLWHTARAIRLLFSIVFWAFLMLSSAVLFVGA
CCCCEEECCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLVWLVTLPFDRDGRVLHLYSCFWAQLYFYVNPLWHLEVDGREHLPWRGPAVLVSNHESL
HHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCEEEEECCCHH
GDILVLFGLYRPFKWVSKASNFKLPLIGWNMRLNRYVPLVRGDRASITKMLADCEYWLSR
HHHHHHHHHHHHHHHHHCCCCCCEEEEEECEEECCCCCEEECCHHHHHHHHHHHHHHHHC
GVPILMFPEGTRSSDGVVKPFKDGAFALALKQRCPVIPVVLTGTARTLPKHGLVLETTAR
CCEEEEECCCCCCCCCCCCCCCCCCEEEEHHHCCCEEEEEEECCCHHCCCCCEEEEECCE
CHVQVMPPVDPSAFTDVASLREHVRNLIVSEKARIEALTPGA
EEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1557036; 9278503 [H]