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The map label for this gene is 108763645

Identifier: 108763645

GI number: 108763645

Start: 1297963

End: 1299120

Strand: Direct

Name: 108763645

Synonym: MXAN_1115

Alternate gene names: NA

Gene position: 1297963-1299120 (Clockwise)

Preceding gene: 108760661

Following gene: 108762236

Centisome position: 14.2

GC content: 69.08

Gene sequence:

>1158_bases
ATGCGCGCCGCGCGAGGATCCTTTCAAATCGGCTCGTTCCGCGGCATTCCCGTCCGCGTCCACTTCTCGCTGTTGCTGGT
CCTTCCGCTGCTTGCGTTTCTATTCGGCGGCGCCTTCCAGCGGGCGGCGGAGGTGGCCGAAGTCCCCCCGGAGCGACTCA
GCGGCTCGCCCGCGCTGTGGGGGCTGGTGGTGGCGTTGGGCTTGTTCGCGTCCGTGTTCATTCACGAACTGGCGCACACC
GTGTACGCGCTGCGCCGCGGCGGGAGGGTGCGCTCGATTACGTTGATGATGGTGGGCGGTGTGTCGGAGTTGACGGAGGC
GCCGCCGCGTCCCCGGGATGAAGCGCTGATGGCCGCGGTGGGGCCGCTGACGAGCATCCTGCTGGCGGTGCTGCTCGGCG
GCGCGACGTGGCTGCTCCAGGAGGTGCGCTCGTTCAACCTCCAGTTCGCGTTCTTCTACATGGCCAGCCTGAACCTGTTC
CTGGGTGTGTTCAATCTGCTGCCCGCGTTCCCCATGGATGGGGGGCGCATCGTCCGCGCGTCGCTGGCGGGACGGCTGGG
GATGGTGCGCGCAACGCAGGTGGCGTCCTGGCTGGGACGTGGGTTCGCGGTGTTGTTCGGTGTGTGGGCGGTGCTGTCGC
TCAATCCGTTCCTGGTCGTCATCGCGTTCTTCATCTTCATGGGCGCGCAGGGGGAGGCGCAGCAGGTGCGGATGAAGATG
ACGCTGGAGCGTGTGCCGGTGGCCGACTTGATGACGCCGCGCCGGGTGGGTGTGGACGCGGGGGCGTCGCTGGAGCAGGC
GCTGTGGGACTTGCGGCGTGCGAGGCTGTTGCTGCTGCCGGTGACGGAGGACGAAAGGCCGGTGGGGCAGGTGTCGCTGG
AGACGGTGCGGGCCGTGCCGGATTCGGAGCGGATGACGCGCACCGTGCGCGAGGTGATGGTGCCCGCCGTGGTGGTGCGG
CTGGATGAGGATGGGTGGACGGCGCTGCGGCGCATGGCCGAGGAGGAGAGGCCCCAACTCGTCGTGGTGGAGGCGGATGG
GGTGCTGGCGGGGACACTCGACGTGAACGATGTGCAGCGCGGTATGGCGCTGTATCAGGCGCGCGAGGAGCGCAGCGGTC
AGCAGGATCGGCGGTGGCGGCAGGAGCGGCCGGCGTAA

Upstream 100 bases:

>100_bases
GAGGAGCGGACATTCGGGGGGCGGGCAGCCGGCCGGGCCGCTTCCAGGTCCGTGCGCGCCGGGTGGAGGGGACGGAGGTT
GAAGCCATAGGAGGGCCGCC

Downstream 100 bases:

>100_bases
CGGGACTCAGTCCGTCACGAACCACAGGCCCACGGTGCCGCCACCCTGCTGCGAGAAGATGGCGTCGCTCGTTTGGAGTT
CATGTTCGGCGGCGTGCTTG

Product: SREBP protease

Products: NA

Alternate protein names: Site-2-type intermembrane protease [H]

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MRAARGSFQIGSFRGIPVRVHFSLLLVLPLLAFLFGGAFQRAAEVAEVPPERLSGSPALWGLVVALGLFASVFIHELAHT
VYALRRGGRVRSITLMMVGGVSELTEAPPRPRDEALMAAVGPLTSILLAVLLGGATWLLQEVRSFNLQFAFFYMASLNLF
LGVFNLLPAFPMDGGRIVRASLAGRLGMVRATQVASWLGRGFAVLFGVWAVLSLNPFLVVIAFFIFMGAQGEAQQVRMKM
TLERVPVADLMTPRRVGVDAGASLEQALWDLRRARLLLLPVTEDERPVGQVSLETVRAVPDSERMTRTVREVMVPAVVVR
LDEDGWTALRRMAEEERPQLVVVEADGVLAGTLDVNDVQRGMALYQAREERSGQQDRRWRQERPA

Sequences:

>Translated_385_residues
MRAARGSFQIGSFRGIPVRVHFSLLLVLPLLAFLFGGAFQRAAEVAEVPPERLSGSPALWGLVVALGLFASVFIHELAHT
VYALRRGGRVRSITLMMVGGVSELTEAPPRPRDEALMAAVGPLTSILLAVLLGGATWLLQEVRSFNLQFAFFYMASLNLF
LGVFNLLPAFPMDGGRIVRASLAGRLGMVRATQVASWLGRGFAVLFGVWAVLSLNPFLVVIAFFIFMGAQGEAQQVRMKM
TLERVPVADLMTPRRVGVDAGASLEQALWDLRRARLLLLPVTEDERPVGQVSLETVRAVPDSERMTRTVREVMVPAVVVR
LDEDGWTALRRMAEEERPQLVVVEADGVLAGTLDVNDVQRGMALYQAREERSGQQDRRWRQERPA
>Mature_385_residues
MRAARGSFQIGSFRGIPVRVHFSLLLVLPLLAFLFGGAFQRAAEVAEVPPERLSGSPALWGLVVALGLFASVFIHELAHT
VYALRRGGRVRSITLMMVGGVSELTEAPPRPRDEALMAAVGPLTSILLAVLLGGATWLLQEVRSFNLQFAFFYMASLNLF
LGVFNLLPAFPMDGGRIVRASLAGRLGMVRATQVASWLGRGFAVLFGVWAVLSLNPFLVVIAFFIFMGAQGEAQQVRMKM
TLERVPVADLMTPRRVGVDAGASLEQALWDLRRARLLLLPVTEDERPVGQVSLETVRAVPDSERMTRTVREVMVPAVVVR
LDEDGWTALRRMAEEERPQLVVVEADGVLAGTLDVNDVQRGMALYQAREERSGQQDRRWRQERPA

Specific function: Unknown

COG id: COG1994

COG function: function code R; Zn-dependent proteases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000644
- InterPro:   IPR008915
- InterPro:   IPR016483 [H]

Pfam domain/function: PF00571 CBS; PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 42427; Mature: 42427

Theoretical pI: Translated: 10.86; Mature: 10.86

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAARGSFQIGSFRGIPVRVHFSLLLVLPLLAFLFGGAFQRAAEVAEVPPERLSGSPALW
CCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCHHHCCCCCHHH
GLVVALGLFASVFIHELAHTVYALRRGGRVRSITLMMVGGVSELTEAPPRPRDEALMAAV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCHHHHHCCCCCCCHHHHHHHH
GPLTSILLAVLLGGATWLLQEVRSFNLQFAFFYMASLNLFLGVFNLLPAFPMDGGRIVRA
HHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHH
SLAGRLGMVRATQVASWLGRGFAVLFGVWAVLSLNPFLVVIAFFIFMGAQGEAQQVRMKM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHH
TLERVPVADLMTPRRVGVDAGASLEQALWDLRRARLLLLPVTEDERPVGQVSLETVRAVP
HHHHCCHHHHCCCHHCCCCCCCHHHHHHHHHHHCEEEEEECCCCCCCCCHHHHHHHHCCC
DSERMTRTVREVMVPAVVVRLDEDGWTALRRMAEEERPQLVVVEADGVLAGTLDVNDVQR
CHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHCCCCEEEEECCCEEEECCCHHHHHH
GMALYQAREERSGQQDRRWRQERPA
HHHHHHHHHHHCCHHHHHHHHCCCC
>Mature Secondary Structure
MRAARGSFQIGSFRGIPVRVHFSLLLVLPLLAFLFGGAFQRAAEVAEVPPERLSGSPALW
CCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCHHHCCCCCHHH
GLVVALGLFASVFIHELAHTVYALRRGGRVRSITLMMVGGVSELTEAPPRPRDEALMAAV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCHHHHHCCCCCCCHHHHHHHH
GPLTSILLAVLLGGATWLLQEVRSFNLQFAFFYMASLNLFLGVFNLLPAFPMDGGRIVRA
HHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHH
SLAGRLGMVRATQVASWLGRGFAVLFGVWAVLSLNPFLVVIAFFIFMGAQGEAQQVRMKM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHH
TLERVPVADLMTPRRVGVDAGASLEQALWDLRRARLLLLPVTEDERPVGQVSLETVRAVP
HHHHCCHHHHCCCHHCCCCCCCHHHHHHHHHHHCEEEEEECCCCCCCCCHHHHHHHHCCC
DSERMTRTVREVMVPAVVVRLDEDGWTALRRMAEEERPQLVVVEADGVLAGTLDVNDVQR
CHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHCCCCEEEEECCCEEEECCCHHHHHH
GMALYQAREERSGQQDRRWRQERPA
HHHHHHHHHHHCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]