Click here to switch to the map view.

The map label for this gene is napA [H]

Identifier: 108763391

GI number: 108763391

Start: 307792

End: 309939

Strand: Direct

Name: napA [H]

Synonym: MXAN_0260

Alternate gene names: 108763391

Gene position: 307792-309939 (Clockwise)

Preceding gene: 108763938

Following gene: 108758699

Centisome position: 3.37

GC content: 70.34

Gene sequence:

>2148_bases
ATGCACACCAACGCACTCGCGCTGCTGATCTTGCAGCTCATCGTCATCATCGGCTTGTCGCGGCTCATCGGCCGCGGCGC
GCGGTGGTTGGGACAGCCGTTGGTCATCGCGGAGGTGGTGGCCGGAATCGTCCTGGGGCCCTCGCTGCTGGGCTGGCTGG
CGCCGGACATCATGAACGGGCTGTTCCCGGCCTCGTCGATGCCGGTGCTGACGATGCTCAGCCAGGTGGGCCTGGTGCTG
TTCATGTTCCTCATTGGCCTGGAGCTGGACCCCCAGCTACTCAAGGGCCGGGGGCATGCGTCGGTGGCCATCAGCCACTC
CAGCATCGTCGTCCCCTTCGCGCTGGGCGCGGGCGCGGGCGCGCTGTGGCTCTACAGGAGCCTGTCGTCGCCAGAGGTGC
CGTTCTCCTCGTTCGTGCTCTTCATGGGCGTGGCGATGAGCATCACCGCCTTCCCGGTGCTGGCGCGCATCCTCACCGAG
CGGGGCCTGCTCCAGTCGAAGGTGGGCACGGTGGCCATTGCCTGCGCGGCGGTGGATGACGTCACCGCGTGGTGCCTGCT
GGCCTTCGTCGTCTCCATCGTCCGTGCGTCCAGCCTGGCTCAGGCGGCGCTCACCACGGTGATGGCGCTGGGCTACATCG
CCTTCATGCTGATGGTGGTGCGGCCCTTCCTCGCGCGCCTGGGCGCGCGGGTGGCCAGCCGTGAGGGTCTCACCCAGAAC
GTGGTGGCGGGCACACTGGTGCTGCTGCTGGCGTCCGCGGGCGTGACGGAGCTCATCGGCATCCACGCGCTCTTCGGTGC
CTTCCTCTTCGGCGCGGTGATTCCAAAGGAAGGCCGTCTGGCGGAGACGCTGGCGGAGCGGCTGGAGGACGTGGCGGTGG
TGTTGCTGCTGCCCGTCTTCTTCGCCTTCAGCGGCCTGCGCACGCAGATTGGCCTGCTAAACACCGCGGAGGACTGGCTG
ACGTGCGGCGTCATCATCGTGCTGGCCTGCCTGGGCAAGTTCGGCGGCAGCGCGGTGGCGGCGAGGATGACGGGCCTGCG
GTGGCGCGAGGCGAGCGCCATCGGCATCCTGATGAACACGCGTGGGTTGATGGAGCTCATCGTCCTCAACATCGGCCTGG
ACCTGGGCGTCATCTCACCCCAGCTGTTCACGATGATGGTGCTGATGGCGCTGGTGACGACGTTCATCACCACGCCGCTG
CTGAAGTGGATCTACCCGCTGGAGGAGATTGCCCGCGAGCGCGTGGTGGTGCCGCTGCCGGTGGAGCCGGGCCCTCCGCC
CTACAGCGTGCTGATGTGCGTGTCGCACGGGCAGGCGGGGCCGGGCATGGCCACCCTGGCGCGCTCGTTGTCGGGGCGTG
AAGAGGGCGCGCAGCTTCACGCGCTGCATCTGGTGTCCCCGGAGCGCGCGTCCCTGCGCCCGGCGCAGCAGCGGGCCCCC
GAGGAGGACAGCGCGCTGATGCCGCTCTTGTGGCGGGCCGTAAGCCTGGGGCTCTCCGTGCGGCCGTTGTCGTTCGTCTC
CGCCGAGCCGGCCCAGGACATCTGCCGCACGGCGAAGGCCCGGCGCGCGGACCTGGTCCTGCTGGGGTGGCACAAGCCGC
TCTTCAGCCAGACGATGCTGGGCGGCACGGTGCGTGAGGTGATGCAGGAGGCCAGTGGCCCGGTGGCGGTGCTGGTGGAC
CGGGGCCTGTCGGACATCAAGCGCGTGCTGGTGCCCTTCGCCGGCAGCCGGCATGACCGCGCGGCCCTGGCCCTGGCCCG
GCGGCTGAGGCAGCAGGCGGACGCCGAGGTGACGGTGCTGCACGTGACGTCGGACCTCGGCGGCAACGGCGGAGCCCGGG
CGCAGGTGGAGGCGCTGTTCCCGGCGAACGAGGGCGGCGTGACGTTGAAGGAGGTGCGCAGCGACGCGCCGGACGAGGCC
GCCCTGGGTGAGGCGCGCCACGGCTATGACCTGGTGATTGTCGGCATCGGCGCGCAGTGGGGGCTGGAGGACAAGGTCTT
CGGCCTGCAGCGCGAGCGCATCATCCGGGACGCGCCGGGCTCGCTGCTGGTGGTGTCCGACGCGTCTCCCGCCACGGCGG
CGGAGTCCACCTCCGAAGCCGCCAACGACGGGGCCACTGCAGTCCGGGTGTTGCCCGCGAGGAGCTGA

Upstream 100 bases:

>100_bases
GCAGGCAGGCGGGTCCTGTTTGACGCTCCGCGTTCCCCCCGGTTGACGCCTCGAAATCAGGTTGGTAAGTGCCAGCTTAA
CACTTCATGTGGAGGGCCGG

Downstream 100 bases:

>100_bases
TGCATCTGGGAGCCACCCTCCGGCTGTTGCGCACGGATGCGGGCCTGTCGCTGCGGGACCTGGCGCGCCGTATCGGCGTG
TCCAGCGCGTACCTCAGCCG

Product: putative cation transporter/universal stress family protein

Products: Proton [Cytoplasm]; K (I) [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 715; Mature: 715

Protein sequence:

>715_residues
MHTNALALLILQLIVIIGLSRLIGRGARWLGQPLVIAEVVAGIVLGPSLLGWLAPDIMNGLFPASSMPVLTMLSQVGLVL
FMFLIGLELDPQLLKGRGHASVAISHSSIVVPFALGAGAGALWLYRSLSSPEVPFSSFVLFMGVAMSITAFPVLARILTE
RGLLQSKVGTVAIACAAVDDVTAWCLLAFVVSIVRASSLAQAALTTVMALGYIAFMLMVVRPFLARLGARVASREGLTQN
VVAGTLVLLLASAGVTELIGIHALFGAFLFGAVIPKEGRLAETLAERLEDVAVVLLLPVFFAFSGLRTQIGLLNTAEDWL
TCGVIIVLACLGKFGGSAVAARMTGLRWREASAIGILMNTRGLMELIVLNIGLDLGVISPQLFTMMVLMALVTTFITTPL
LKWIYPLEEIARERVVVPLPVEPGPPPYSVLMCVSHGQAGPGMATLARSLSGREEGAQLHALHLVSPERASLRPAQQRAP
EEDSALMPLLWRAVSLGLSVRPLSFVSAEPAQDICRTAKARRADLVLLGWHKPLFSQTMLGGTVREVMQEASGPVAVLVD
RGLSDIKRVLVPFAGSRHDRAALALARRLRQQADAEVTVLHVTSDLGGNGGARAQVEALFPANEGGVTLKEVRSDAPDEA
ALGEARHGYDLVIVGIGAQWGLEDKVFGLQRERIIRDAPGSLLVVSDASPATAAESTSEAANDGATAVRVLPARS

Sequences:

>Translated_715_residues
MHTNALALLILQLIVIIGLSRLIGRGARWLGQPLVIAEVVAGIVLGPSLLGWLAPDIMNGLFPASSMPVLTMLSQVGLVL
FMFLIGLELDPQLLKGRGHASVAISHSSIVVPFALGAGAGALWLYRSLSSPEVPFSSFVLFMGVAMSITAFPVLARILTE
RGLLQSKVGTVAIACAAVDDVTAWCLLAFVVSIVRASSLAQAALTTVMALGYIAFMLMVVRPFLARLGARVASREGLTQN
VVAGTLVLLLASAGVTELIGIHALFGAFLFGAVIPKEGRLAETLAERLEDVAVVLLLPVFFAFSGLRTQIGLLNTAEDWL
TCGVIIVLACLGKFGGSAVAARMTGLRWREASAIGILMNTRGLMELIVLNIGLDLGVISPQLFTMMVLMALVTTFITTPL
LKWIYPLEEIARERVVVPLPVEPGPPPYSVLMCVSHGQAGPGMATLARSLSGREEGAQLHALHLVSPERASLRPAQQRAP
EEDSALMPLLWRAVSLGLSVRPLSFVSAEPAQDICRTAKARRADLVLLGWHKPLFSQTMLGGTVREVMQEASGPVAVLVD
RGLSDIKRVLVPFAGSRHDRAALALARRLRQQADAEVTVLHVTSDLGGNGGARAQVEALFPANEGGVTLKEVRSDAPDEA
ALGEARHGYDLVIVGIGAQWGLEDKVFGLQRERIIRDAPGSLLVVSDASPATAAESTSEAANDGATAVRVLPARS
>Mature_715_residues
MHTNALALLILQLIVIIGLSRLIGRGARWLGQPLVIAEVVAGIVLGPSLLGWLAPDIMNGLFPASSMPVLTMLSQVGLVL
FMFLIGLELDPQLLKGRGHASVAISHSSIVVPFALGAGAGALWLYRSLSSPEVPFSSFVLFMGVAMSITAFPVLARILTE
RGLLQSKVGTVAIACAAVDDVTAWCLLAFVVSIVRASSLAQAALTTVMALGYIAFMLMVVRPFLARLGARVASREGLTQN
VVAGTLVLLLASAGVTELIGIHALFGAFLFGAVIPKEGRLAETLAERLEDVAVVLLLPVFFAFSGLRTQIGLLNTAEDWL
TCGVIIVLACLGKFGGSAVAARMTGLRWREASAIGILMNTRGLMELIVLNIGLDLGVISPQLFTMMVLMALVTTFITTPL
LKWIYPLEEIARERVVVPLPVEPGPPPYSVLMCVSHGQAGPGMATLARSLSGREEGAQLHALHLVSPERASLRPAQQRAP
EEDSALMPLLWRAVSLGLSVRPLSFVSAEPAQDICRTAKARRADLVLLGWHKPLFSQTMLGGTVREVMQEASGPVAVLVD
RGLSDIKRVLVPFAGSRHDRAALALARRLRQQADAEVTVLHVTSDLGGNGGARAQVEALFPANEGGVTLKEVRSDAPDEA
ALGEARHGYDLVIVGIGAQWGLEDKVFGLQRERIIRDAPGSLLVVSDASPATAAESTSEAANDGATAVRVLPARS

Specific function: This is a Na(+)/H(+) antiporter. It can mediate sodium uptake when a transmembrane pH gradient is applied [H]

COG id: COG0475

COG function: function code P; Kef-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6322367, Length=588, Percent_Identity=31.6326530612245, Blast_Score=269, Evalue=1e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR004771 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 75622; Mature: 75622

Theoretical pI: Translated: 7.61; Mature: 7.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTNALALLILQLIVIIGLSRLIGRGARWLGQPLVIAEVVAGIVLGPSLLGWLAPDIMNG
CCCHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
LFPASSMPVLTMLSQVGLVLFMFLIGLELDPQLLKGRGHASVAISHSSIVVPFALGAGAG
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCEEEEEECCCEEEEEECCCCCH
ALWLYRSLSSPEVPFSSFVLFMGVAMSITAFPVLARILTERGLLQSKVGTVAIACAAVDD
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTAWCLLAFVVSIVRASSLAQAALTTVMALGYIAFMLMVVRPFLARLGARVASREGLTQN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VVAGTLVLLLASAGVTELIGIHALFGAFLFGAVIPKEGRLAETLAERLEDVAVVLLLPVF
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
FAFSGLRTQIGLLNTAEDWLTCGVIIVLACLGKFGGSAVAARMTGLRWREASAIGILMNT
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEECCCEEEEEECC
RGLMELIVLNIGLDLGVISPQLFTMMVLMALVTTFITTPLLKWIYPLEEIARERVVVPLP
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEC
VEPGPPPYSVLMCVSHGQAGPGMATLARSLSGREEGAQLHALHLVSPERASLRPAQQRAP
CCCCCCCCEEEEEEECCCCCCCHHHHHHHHCCCCCCCEEEEEEEECCCHHCCCCHHHCCC
EEDSALMPLLWRAVSLGLSVRPLSFVSAEPAQDICRTAKARRADLVLLGWHKPLFSQTML
CCCCHHHHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHH
GGTVREVMQEASGPVAVLVDRGLSDIKRVLVPFAGSRHDRAALALARRLRQQADAEVTVL
HHHHHHHHHHCCCCEEEEECCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEE
HVTSDLGGNGGARAQVEALFPANEGGVTLKEVRSDAPDEAALGEARHGYDLVIVGIGAQW
EEECCCCCCCCCCEEEEEECCCCCCCEEHHHHHCCCCCHHHHCCCCCCCEEEEEEECCCC
GLEDKVFGLQRERIIRDAPGSLLVVSDASPATAAESTSEAANDGATAVRVLPARS
CCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHCHHHHCCCCCCEEEEECCCC
>Mature Secondary Structure
MHTNALALLILQLIVIIGLSRLIGRGARWLGQPLVIAEVVAGIVLGPSLLGWLAPDIMNG
CCCHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
LFPASSMPVLTMLSQVGLVLFMFLIGLELDPQLLKGRGHASVAISHSSIVVPFALGAGAG
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCEEEEEECCCEEEEEECCCCCH
ALWLYRSLSSPEVPFSSFVLFMGVAMSITAFPVLARILTERGLLQSKVGTVAIACAAVDD
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTAWCLLAFVVSIVRASSLAQAALTTVMALGYIAFMLMVVRPFLARLGARVASREGLTQN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VVAGTLVLLLASAGVTELIGIHALFGAFLFGAVIPKEGRLAETLAERLEDVAVVLLLPVF
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
FAFSGLRTQIGLLNTAEDWLTCGVIIVLACLGKFGGSAVAARMTGLRWREASAIGILMNT
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEECCCEEEEEECC
RGLMELIVLNIGLDLGVISPQLFTMMVLMALVTTFITTPLLKWIYPLEEIARERVVVPLP
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEC
VEPGPPPYSVLMCVSHGQAGPGMATLARSLSGREEGAQLHALHLVSPERASLRPAQQRAP
CCCCCCCCEEEEEEECCCCCCCHHHHHHHHCCCCCCCEEEEEEEECCCHHCCCCHHHCCC
EEDSALMPLLWRAVSLGLSVRPLSFVSAEPAQDICRTAKARRADLVLLGWHKPLFSQTML
CCCCHHHHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHH
GGTVREVMQEASGPVAVLVDRGLSDIKRVLVPFAGSRHDRAALALARRLRQQADAEVTVL
HHHHHHHHHHCCCCEEEEECCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEE
HVTSDLGGNGGARAQVEALFPANEGGVTLKEVRSDAPDEAALGEARHGYDLVIVGIGAQW
EEECCCCCCCCCCEEEEEECCCCCCCEEHHHHHCCCCCHHHHCCCCCCCEEEEEEECCCC
GLEDKVFGLQRERIIRDAPGSLLVVSDASPATAAESTSEAANDGATAVRVLPARS
CCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHCHHHHCCCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Cytoplasm] = Proton [Cytoplasm] + K (I) [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1312090; 1325937 [H]