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The map label for this gene is pfpI [H]

Identifier: 108763377

GI number: 108763377

Start: 1349609

End: 1350280

Strand: Reverse

Name: pfpI [H]

Synonym: MXAN_1159

Alternate gene names: 108763377

Gene position: 1350280-1349609 (Counterclockwise)

Preceding gene: 108763967

Following gene: 108757194

Centisome position: 14.77

GC content: 68.3

Gene sequence:

>672_bases
ATGAAGAAGCTGAAAGGGTTGCGAGTGGCCGTGCTCGCGGCGGATGGCTTCGAACAGGTGGAACTGACAGCACCGGTGAA
GAAACTGGAGCGTCAGGGCGCCGACGTGACGATTGTGTCCCCCCACAAGGGCCGCATCCGCGGGATGAACCTTCTCATTC
CAGGGAAAAGGGTGAGCGTGGACGCGTCCCTGCGTGAGGTGAAGGCGGCGGACTTCGACGCGGTCCTCCTCCCAGGAGGT
TTCGTGAACCCGGACCTCCTCCGGCAAAGCGCGCTCGCGCTCGACTTCGTCCGCGACGCCGACGCGCTGGACATGCCCAT
CGCCGTCATCTGCCATGGCCCCTGGGTGCTGATTTCGGCGGGACTCGTGGAGGGACGGGCGCTGGCCGCGTGGCCGGGCA
TCCGCGACGACGTGCGCAACGCGGGTGGCCGCTGGGTGGACGAGCCGGTGATGCGCGATGGCAACTGGGTCTCCAGCCCG
GGACCGCGACAGATGTTCGCGTTCATCAAGGGCATGGTGGAGCTCTTCGCGGAGAAGATGCCGGAGGTCTCTGCTCGTGC
GCCGATGGTGCCCGTGCGCCAGGCAGCGCCTTCCCGGTGGCCGAAGCTGCTCGCGGGAACGCTGGCCACCGCGGCGCTCG
GATTGGGCGCGCGGCGGCTGGCCCTGCGCTGA

Upstream 100 bases:

>100_bases
TCCGTCGGTAGCACGCCCTCCGGGGAGGCACAACGCGGGGCCCAGCGGGAATGCACAGTGTCGAGACGACAAACCGTTCC
GACACAGCGAGGTGTGCGCG

Downstream 100 bases:

>100_bases
GACGTCACCGGCCCTTGGCGAAGCAGCTCGCCGAGGGCCTTCGTCCCGCTGCTACATCCAACCAAGCTGGAGCCGCGCCA
CGTCCGACATCCGCTCCTGC

Product: C56 (PfpI) family peptidase

Products: NA

Alternate protein names: Intracellular protease I [H]

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MKKLKGLRVAVLAADGFEQVELTAPVKKLERQGADVTIVSPHKGRIRGMNLLIPGKRVSVDASLREVKAADFDAVLLPGG
FVNPDLLRQSALALDFVRDADALDMPIAVICHGPWVLISAGLVEGRALAAWPGIRDDVRNAGGRWVDEPVMRDGNWVSSP
GPRQMFAFIKGMVELFAEKMPEVSARAPMVPVRQAAPSRWPKLLAGTLATAALGLGARRLALR

Sequences:

>Translated_223_residues
MKKLKGLRVAVLAADGFEQVELTAPVKKLERQGADVTIVSPHKGRIRGMNLLIPGKRVSVDASLREVKAADFDAVLLPGG
FVNPDLLRQSALALDFVRDADALDMPIAVICHGPWVLISAGLVEGRALAAWPGIRDDVRNAGGRWVDEPVMRDGNWVSSP
GPRQMFAFIKGMVELFAEKMPEVSARAPMVPVRQAAPSRWPKLLAGTLATAALGLGARRLALR
>Mature_223_residues
MKKLKGLRVAVLAADGFEQVELTAPVKKLERQGADVTIVSPHKGRIRGMNLLIPGKRVSVDASLREVKAADFDAVLLPGG
FVNPDLLRQSALALDFVRDADALDMPIAVICHGPWVLISAGLVEGRALAAWPGIRDDVRNAGGRWVDEPVMRDGNWVSSP
GPRQMFAFIKGMVELFAEKMPEVSARAPMVPVRQAAPSRWPKLLAGTLATAALGLGARRLALR

Specific function: Unknown

COG id: COG0693

COG function: function code R; Putative intracellular protease/amidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PfpI endopeptidase domain [H]

Homologues:

Organism=Homo sapiens, GI183227678, Length=187, Percent_Identity=29.4117647058824, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI31543380, Length=187, Percent_Identity=29.4117647058824, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI87082219, Length=166, Percent_Identity=37.9518072289157, Blast_Score=105, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17531319, Length=136, Percent_Identity=29.4117647058824, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI28571932, Length=178, Percent_Identity=30.3370786516854, Blast_Score=81, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24653499, Length=180, Percent_Identity=28.3333333333333, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006286
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: NA

Molecular weight: Translated: 24025; Mature: 24025

Theoretical pI: Translated: 10.82; Mature: 10.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLKGLRVAVLAADGFEQVELTAPVKKLERQGADVTIVSPHKGRIRGMNLLIPGKRVSV
CCCCCCCEEEEEECCCCCEEEEHHHHHHHHHCCCCEEEECCCCCCCCCEEEEECCCEEEE
DASLREVKAADFDAVLLPGGFVNPDLLRQSALALDFVRDADALDMPIAVICHGPWVLISA
CHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCEEEEEC
GLVEGRALAAWPGIRDDVRNAGGRWVDEPVMRDGNWVSSPGPRQMFAFIKGMVELFAEKM
CCCCCCEEEECCCCHHHHHHCCCCCCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
PEVSARAPMVPVRQAAPSRWPKLLAGTLATAALGLGARRLALR
CCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHCCHHHHCCC
>Mature Secondary Structure
MKKLKGLRVAVLAADGFEQVELTAPVKKLERQGADVTIVSPHKGRIRGMNLLIPGKRVSV
CCCCCCCEEEEEECCCCCEEEEHHHHHHHHHCCCCEEEECCCCCCCCCEEEEECCCEEEE
DASLREVKAADFDAVLLPGGFVNPDLLRQSALALDFVRDADALDMPIAVICHGPWVLISA
CHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCEEEEEC
GLVEGRALAAWPGIRDDVRNAGGRWVDEPVMRDGNWVSSPGPRQMFAFIKGMVELFAEKM
CCCCCCEEEECCCCHHHHHHCCCCCCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
PEVSARAPMVPVRQAAPSRWPKLLAGTLATAALGLGARRLALR
CCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA