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The map label for this gene is zraR [H]

Identifier: 108763374

GI number: 108763374

Start: 2495935

End: 2497698

Strand: Reverse

Name: zraR [H]

Synonym: MXAN_2159

Alternate gene names: 108763374

Gene position: 2497698-2495935 (Counterclockwise)

Preceding gene: 108759449

Following gene: 108757283

Centisome position: 27.33

GC content: 72.68

Gene sequence:

>1764_bases
GTGTCGTCCGCTCCCGCCATGCCCCAGCTTCTGGTCCTCCCCGACGGCCGCCGTCTCCCTTTGGACAAGCCCGTCGTCTC
CGTGGGCTCCGACGCCACCTGTGACGCCGTGCTCGTTGCCCCCGGCGTGAAGCCGAGCCACGCGCTGCTGTTCCGCGACG
CGCGAGGTTGGAGCGTGTCCCCGGCGGGCAAGGGCTGTGACATCAAAGTGCGAGGGCGGCGCGTGGACCTGGCGCCCCTG
GAGCCCGGGGACCGCTTCCGCGTGGGCACGGTGGAACTGGAGCTCATCGAAGCGGTGGAGTCCGTCGCGAGTGATGCGGC
GGAGGTGGCCCCCCGGCGACAGGACGGCCGGCTGGTGGCGGTGCTGGCGGAGCTGTCCTCGCGGCTGCTGGTGCAACGCC
CTCCCCTGGAGCTGCTGGAGGTGGCGATGCGGGGGCTCGCCGACGTGGTGGGCGCGGACGTGGGCTTCCTCGTCGCCGCG
GACTCGCGGGAGGGACCTCGGCGCGTGCTGTGTTCCACGGGCGCCAGCCCCGACGCGGCGGTGGTGGACAGTCTGGTGGA
CCGGGTGCTGACCTCGGGTGCCCCGGTGCGGGTGGCCGACGTGGAGGCGGACGCGGCGCTGGCCCGGGCGCCCAGCATGG
AAGCCCTGCGGCTGGGCTCCGCGCTGGTGGTGCCGCTGCGCGTGGAGCCGGTGCCGCTGTCCGTGGTGTACCTGGGACGG
AGGTTGGGTGCTCCGGCCTTTTCAGCGGTGGCGCTGGAGGAGGCCATGGCGCTCTCCGCGCTGACGGCGCTGCTCCTGTC
GACCCGGCGCGAATTGACGGAGCTGCGCGCGCAGGTGGAGGGCCTCACCCGCCGAATCGAAGCCGCGACGTTCGAAGGGC
TCATCGGCGAATCCCCTTCGATGCGCGCCCTATACCGGCAGGTGGAGCGACTGGGGCCCACGCCGCTCAACGTCCTCGTC
ACAGGCGAGACAGGCACGGGCAAGGAGCTGGTGGCGCGGGCACTCCACCGGCGCAGTGGCCGGCGCGGCCGGCTGGTGGC
CATCAACTGCGCGGCGCTGCCGGAGAGCCTCATCGAGCGCGAACTGTTCGGCCATGCGCGTGGCGCGTTCACCGGCGCGG
GCACGGAGCGGGCGGGACTGGTGGAAGCGGCCGACGGTGGCACCCTCTTCCTGGATGAGATTGGGGACATGCCGCTGTCG
CTCCAGACGCGTTTGCTGCGTGTGGTGCAGGAGCGCGAGGTCACCCGCCTGGGCGAACACCAGCCGCGCAAGGTGGACGT
GCGCGTGGTGTCCGCGACCCATGTGGCCCTGGAGGAGGCGGTGCGGCGGGGCACCTTCCGCGCGGACCTGCGCTTCCGGC
TGGAAGAGGTGCGTGTCGACGTGCCGCCGCTGAGAGCGCGTGGTGAGGACGTGCTGCTCATCGCCCACCATGTGCTGGCG
CAAGAGGCGCGCAAGGCGCGAGGCTTCACGCAGAAGGCCTCGGAGGCGCTGCGGGGGCACCCCTTCCCTGGCAACGTGCG
AGAGCTGGCGTCGCGCGTGCGCCGCGCGGCGGTGTTGGCGACGGACGAGTTGTTGCGCCCCGAGGACCTGGAGCTGGGCG
GCGACGCAGCGCCCATGATTCCCCTGGAGGAGGCGCGGGAGGCGTTCGTCCAGCGCTACGTGCGGGAGGCCATCGCCCGC
TGCGGCGGCAGTAAGAAGGACGCGGCGGCGGCGCTGGGCATCGGTCTTCGCTCGCTGTTTCGCTACCTCGGCGAAGGGGA
CTGA

Upstream 100 bases:

>100_bases
CGTCGAAGCACAGGCGATTGGCGACGGCACGGGGCCCCCTCTTCGGCACGCCCCTTCCGGGCCCCGCATGCGCACGCCCC
CGCATTCCTGATATGCGACT

Downstream 100 bases:

>100_bases
CAGGCCGCCTCCTCTGGAGGGCTTGTCCGCGTGCCAGTCCTGGCACGTTTCCCCCGGCATCAGGTGCTCGGAGGGTCAGG
GGCGTCATGCAACCCCGTGG

Product: sigma-54 dependent trancsriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 587; Mature: 586

Protein sequence:

>587_residues
MSSAPAMPQLLVLPDGRRLPLDKPVVSVGSDATCDAVLVAPGVKPSHALLFRDARGWSVSPAGKGCDIKVRGRRVDLAPL
EPGDRFRVGTVELELIEAVESVASDAAEVAPRRQDGRLVAVLAELSSRLLVQRPPLELLEVAMRGLADVVGADVGFLVAA
DSREGPRRVLCSTGASPDAAVVDSLVDRVLTSGAPVRVADVEADAALARAPSMEALRLGSALVVPLRVEPVPLSVVYLGR
RLGAPAFSAVALEEAMALSALTALLLSTRRELTELRAQVEGLTRRIEAATFEGLIGESPSMRALYRQVERLGPTPLNVLV
TGETGTGKELVARALHRRSGRRGRLVAINCAALPESLIERELFGHARGAFTGAGTERAGLVEAADGGTLFLDEIGDMPLS
LQTRLLRVVQEREVTRLGEHQPRKVDVRVVSATHVALEEAVRRGTFRADLRFRLEEVRVDVPPLRARGEDVLLIAHHVLA
QEARKARGFTQKASEALRGHPFPGNVRELASRVRRAAVLATDELLRPEDLELGGDAAPMIPLEEAREAFVQRYVREAIAR
CGGSKKDAAAALGIGLRSLFRYLGEGD

Sequences:

>Translated_587_residues
MSSAPAMPQLLVLPDGRRLPLDKPVVSVGSDATCDAVLVAPGVKPSHALLFRDARGWSVSPAGKGCDIKVRGRRVDLAPL
EPGDRFRVGTVELELIEAVESVASDAAEVAPRRQDGRLVAVLAELSSRLLVQRPPLELLEVAMRGLADVVGADVGFLVAA
DSREGPRRVLCSTGASPDAAVVDSLVDRVLTSGAPVRVADVEADAALARAPSMEALRLGSALVVPLRVEPVPLSVVYLGR
RLGAPAFSAVALEEAMALSALTALLLSTRRELTELRAQVEGLTRRIEAATFEGLIGESPSMRALYRQVERLGPTPLNVLV
TGETGTGKELVARALHRRSGRRGRLVAINCAALPESLIERELFGHARGAFTGAGTERAGLVEAADGGTLFLDEIGDMPLS
LQTRLLRVVQEREVTRLGEHQPRKVDVRVVSATHVALEEAVRRGTFRADLRFRLEEVRVDVPPLRARGEDVLLIAHHVLA
QEARKARGFTQKASEALRGHPFPGNVRELASRVRRAAVLATDELLRPEDLELGGDAAPMIPLEEAREAFVQRYVREAIAR
CGGSKKDAAAALGIGLRSLFRYLGEGD
>Mature_586_residues
SSAPAMPQLLVLPDGRRLPLDKPVVSVGSDATCDAVLVAPGVKPSHALLFRDARGWSVSPAGKGCDIKVRGRRVDLAPLE
PGDRFRVGTVELELIEAVESVASDAAEVAPRRQDGRLVAVLAELSSRLLVQRPPLELLEVAMRGLADVVGADVGFLVAAD
SREGPRRVLCSTGASPDAAVVDSLVDRVLTSGAPVRVADVEADAALARAPSMEALRLGSALVVPLRVEPVPLSVVYLGRR
LGAPAFSAVALEEAMALSALTALLLSTRRELTELRAQVEGLTRRIEAATFEGLIGESPSMRALYRQVERLGPTPLNVLVT
GETGTGKELVARALHRRSGRRGRLVAINCAALPESLIERELFGHARGAFTGAGTERAGLVEAADGGTLFLDEIGDMPLSL
QTRLLRVVQEREVTRLGEHQPRKVDVRVVSATHVALEEAVRRGTFRADLRFRLEEVRVDVPPLRARGEDVLLIAHHVLAQ
EARKARGFTQKASEALRGHPFPGNVRELASRVRRAAVLATDELLRPEDLELGGDAAPMIPLEEAREAFVQRYVREAIARC
GGSKKDAAAALGIGLRSLFRYLGEGD

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=316, Percent_Identity=45.253164556962, Blast_Score=243, Evalue=2e-65,
Organism=Escherichia coli, GI1789233, Length=317, Percent_Identity=41.9558359621451, Blast_Score=238, Evalue=9e-64,
Organism=Escherichia coli, GI1788550, Length=409, Percent_Identity=35.9413202933985, Blast_Score=234, Evalue=2e-62,
Organism=Escherichia coli, GI1790299, Length=326, Percent_Identity=42.3312883435583, Blast_Score=227, Evalue=2e-60,
Organism=Escherichia coli, GI1788905, Length=300, Percent_Identity=41.6666666666667, Blast_Score=224, Evalue=1e-59,
Organism=Escherichia coli, GI87082152, Length=322, Percent_Identity=43.167701863354, Blast_Score=217, Evalue=2e-57,
Organism=Escherichia coli, GI87082117, Length=277, Percent_Identity=45.4873646209386, Blast_Score=211, Evalue=1e-55,
Organism=Escherichia coli, GI1786524, Length=316, Percent_Identity=43.0379746835443, Blast_Score=209, Evalue=3e-55,
Organism=Escherichia coli, GI1789087, Length=286, Percent_Identity=42.6573426573427, Blast_Score=208, Evalue=1e-54,
Organism=Escherichia coli, GI87081872, Length=231, Percent_Identity=46.3203463203463, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI1787583, Length=302, Percent_Identity=34.1059602649007, Blast_Score=159, Evalue=5e-40,
Organism=Escherichia coli, GI1789828, Length=243, Percent_Identity=32.0987654320988, Blast_Score=113, Evalue=4e-26,
Organism=Escherichia coli, GI87081858, Length=313, Percent_Identity=28.4345047923323, Blast_Score=96, Evalue=9e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 62891; Mature: 62760

Theoretical pI: Translated: 7.94; Mature: 7.94

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSAPAMPQLLVLPDGRRLPLDKPVVSVGSDATCDAVLVAPGVKPSHALLFRDARGWSVS
CCCCCCCCEEEECCCCCCCCCCCCCEECCCCCCCCEEEEECCCCCCCEEEEECCCCCCCC
PAGKGCDIKVRGRRVDLAPLEPGDRFRVGTVELELIEAVESVASDAAEVAPRRQDGRLVA
CCCCCCEEEECCCEEEECCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCEEH
VLAELSSRLLVQRPPLELLEVAMRGLADVVGADVGFLVAADSREGPRRVLCSTGASPDAA
HHHHHHHHHEECCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEECCCCCCCHH
VVDSLVDRVLTSGAPVRVADVEADAALARAPSMEALRLGSALVVPLRVEPVPLSVVYLGR
HHHHHHHHHHHCCCCEEEEECCHHHHHHCCCCHHHHHCCCEEEEEEEECCCCCHHHHHHH
RLGAPAFSAVALEEAMALSALTALLLSTRRELTELRAQVEGLTRRIEAATFEGLIGESPS
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
MRALYRQVERLGPTPLNVLVTGETGTGKELVARALHRRSGRRGRLVAINCAALPESLIER
HHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCEEEEEHHHCCHHHHHH
ELFGHARGAFTGAGTERAGLVEAADGGTLFLDEIGDMPLSLQTRLLRVVQEREVTRLGEH
HHHHHHCCCCCCCCCCCCCEEEECCCCEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHCCC
QPRKVDVRVVSATHVALEEAVRRGTFRADLRFRLEEVRVDVPPLRARGEDVLLIAHHVLA
CCCEEEEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEHHHHHHH
QEARKARGFTQKASEALRGHPFPGNVRELASRVRRAAVLATDELLRPEDLELGGDAAPMI
HHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
PLEEAREAFVQRYVREAIARCGGSKKDAAAALGIGLRSLFRYLGEGD
CHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SSAPAMPQLLVLPDGRRLPLDKPVVSVGSDATCDAVLVAPGVKPSHALLFRDARGWSVS
CCCCCCCEEEECCCCCCCCCCCCCEECCCCCCCCEEEEECCCCCCCEEEEECCCCCCCC
PAGKGCDIKVRGRRVDLAPLEPGDRFRVGTVELELIEAVESVASDAAEVAPRRQDGRLVA
CCCCCCEEEECCCEEEECCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCEEH
VLAELSSRLLVQRPPLELLEVAMRGLADVVGADVGFLVAADSREGPRRVLCSTGASPDAA
HHHHHHHHHEECCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEECCCCCCCHH
VVDSLVDRVLTSGAPVRVADVEADAALARAPSMEALRLGSALVVPLRVEPVPLSVVYLGR
HHHHHHHHHHHCCCCEEEEECCHHHHHHCCCCHHHHHCCCEEEEEEEECCCCCHHHHHHH
RLGAPAFSAVALEEAMALSALTALLLSTRRELTELRAQVEGLTRRIEAATFEGLIGESPS
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
MRALYRQVERLGPTPLNVLVTGETGTGKELVARALHRRSGRRGRLVAINCAALPESLIER
HHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCEEEEEHHHCCHHHHHH
ELFGHARGAFTGAGTERAGLVEAADGGTLFLDEIGDMPLSLQTRLLRVVQEREVTRLGEH
HHHHHHCCCCCCCCCCCCCEEEECCCCEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHCCC
QPRKVDVRVVSATHVALEEAVRRGTFRADLRFRLEEVRVDVPPLRARGEDVLLIAHHVLA
CCCEEEEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEHHHHHHH
QEARKARGFTQKASEALRGHPFPGNVRELASRVRRAAVLATDELLRPEDLELGGDAAPMI
HHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
PLEEAREAFVQRYVREAIARCGGSKKDAAAALGIGLRSLFRYLGEGD
CHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11243806 [H]