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The map label for this gene is ctpC [H]

Identifier: 108763297

GI number: 108763297

Start: 5232631

End: 5235063

Strand: Reverse

Name: ctpC [H]

Synonym: MXAN_4270

Alternate gene names: 108763297

Gene position: 5235063-5232631 (Counterclockwise)

Preceding gene: 108763821

Following gene: 108759953

Centisome position: 57.28

GC content: 71.6

Gene sequence:

>2433_bases
ATGCGGGCGGAGGTGGAGTTCCTGAGTGGCATGGCGCGCGGCTTCAAGGGGCGCGCGCACGATGTCCTGGATGGGCATCA
GCGGCCCGTGTCCGTCCACGTCACGGACGTGGCTCCGGGCCGGCTCCTCATCCGAGGCGCGGCGGAGGATTCCAAGACGC
TGCGCCAGTTGCTCGGCTGGTTGGAGTCCCGCCCCGAAGTCCAGGTGGCCACGTGTCAGCGCAGCACGGGCCTGGTCAAG
GTGCACTACCAGGAGGCCTCGCGCTTCCCTGGCGCGTTCGCGCTGCGGGTGCGGGACTTCGCCTTCACGTTGCACCAGCT
TCCGCCCAAGCCGTTCCAGGTGGAGGTGCTGCACGCACTGCCCGGTCGCGTGCGCTTGCACGTCCGAGGGCTCGAGGACG
ACGACATCCTCAAGCTGGCGGCCTGGGCCGCGACGCTGGCGGGGGTGCACAAGGCGAGCGCCTCGCCGGCCATCCATTCG
CTGGTGGTGAGCTTCGACCCGGAGATGCTCAACGCGAGCCAGTTGATGGCGGCCCTGCGTACGAGCGATCCATCCACCTG
GCCCGCCGCGCCCGAGCCGCCCCGGCGGGAATGGGCCGCCACTGTCTTCAATTCGGCGGTGCTCGCCGCGTGCGTCGTGA
ACGCGGCGCCCATGCCCGTGTTGGCCGCGGGCGTCGCGTTGACGAGCCTGCCGCTGGCACAGCGCGCCTTCCAGTCCGTC
GCGGAGCGGCGCATCACCGTGGACCTGCTCGACCTGGTGGCGGTGGGGGTATCCCTGGCCACGGGGCAGGTGCGGACCGC
GGCGCTCATCACCTCCCTGCTGGGCATTGGCGACTTGTTGATTGAGCGCAGCGCGGACCGCGCCCGGTCCGCCATCTCCC
GGCTGATGCGGCTGGAGGTGCTGTACGCCTGGCGACTGCGGGTGGACGGAGAGGTGGAGCAGGTCCGGGCGGACCGGCTC
AAGGAGGGCGACCTCATCGTCGTGCACGCGGGGGAGAGCGTGCCCGCCGACGGGACGGTGGTGTCCGGCACTGCGTGGGT
GGATGAGAAGGCGCTCACGGGTGAATCCGAGCCCCGCGTCCGCGAGGCGGGAGACCGCGTGCTGGCCGCGTCCGTGGTGG
GCGAGGGCAGCCTTCGGGTGCGGGTGGTGCGCGCGGGCGTGGAGACCACGGCGGCCAAGATTCTCCACATCCTCGAAGGC
GCGGGCGCCAAGCCCATGACGCTGCAGGCGAAGGTGGACTCGGTGGCGAACGGCGTCGTGCTGCCGACCTTCGGGCTCGC
CGCGGCGACGTGGCTGTGGACGCGCGAGGCGTCACGGCCCATCAGCATCCTCATCACGGACTTCGGGACGGGTGTTCGCA
TCGTCGTGCCGGCGAGCGCGCTGGTGGCGATGACGCTCGCGGCGCGTCAGGGCATCCTCATCAAGGGGGCGCAGTACCTG
GAGCGGCTGGCCCAGGCGGACACCATCGTCTTCGACAAGACAGGTACGCTGACGTTGGGTGTCCCGGAAGTGGTGGACGT
CATTCCCGTTCGGGGCTGGGACGCGCGCGAGGTGCTGTCGCTGAGCGCCGCTGCCGAGCTGCGTCAGTCTCATCCCGTGG
CGGAGGCGGTGCGCAGGCACGCCCAGACGCAAGGCGTAGAGGTGCCGCAGCCCGAGGCGGGACTGGAGGAGTTCGTCCTG
GGGCGGGGCGTCTGCGCCCAGGTGAACGGGCGCCGCGTCTGCGTGGGCAGCGCGCGCTGGATGCAGCAGCAAGGTGTGGA
CGTGACGGACGCGGGCTCGGCGCTGGCCCGGTCCGTGCCGCGCGATGTCGCCACCCTGTGGGTCACCGTGGATGGCGCGC
TGGCCGGGTGCATCAGCTACGTGGAGACACTGCGGCCGGAGAGCGCGGGCGTGGTGCAGTCCCTGAAGGAGAACGGGCGC
AGGCGCATCGTGCTGCTGTCCGGGGACTCGCCGTCGCGGGTGGCGGAGGTCGCGAGCCGGTTGGGCGTGGACGAGGCCAT
CGCGGAGCTGCTTCCCGAGGACAAGGCCACGCAAGTGCGCACGCTCCGGCGCCAGGGACGCATCGTGGCCATGGTGGGGG
ATGGCATCAATGACGCCCCGGCGCTCGCGCTCGCCGACGTTGGTATCTCCTTGAGGGGGGCGACGGACGTGGCGCTGGAG
ACGGCGGACGTGGTGCTGCTGCGAGGCAGCCTCGATGACCTGTTGCTGGCGTTCGACGCAGGCCGCGACACCCTGGCCCG
CGTCCACCTGGGGCTCGGGCTGGTGCTGGTGCCCAATGCCGTGGCCATGGTGCTCGCGGCGCTGGGATGGCTGCCGCCTG
TCGCCGCCGCCGTGGTCAACAACGGCTCCACGGTGGTGGCTGGCTTCGCCGCGCTGGCGCCGCTGTTCCGTCAGGCGCGC
GCCGCCCAGCGCGAGGATTCCACCACCCACTGA

Upstream 100 bases:

>100_bases
GAGCTGGAAGACGCCGCGCGCGTCAGCGGGACGGTGCCCTTCCGGCCCCGGCCCCACGTGTGAGGTCGCGGTTGCACTGC
GTTCAGCTCGGGGGGCGTTC

Downstream 100 bases:

>100_bases
GCATCAGGGCGTCTGGGGCGCGGCCGCCTGGGGCCTGGGCTTCACGTCCGTGTTCTGGCCGGCCATGATTTGCCACTGCC
CGTTCACGTGCTTCATCACG

Product: cation transporter E1-E2 family ATPase

Products: ADP; Orthophosphate. [C]

Alternate protein names: NA

Number of amino acids: Translated: 810; Mature: 810

Protein sequence:

>810_residues
MRAEVEFLSGMARGFKGRAHDVLDGHQRPVSVHVTDVAPGRLLIRGAAEDSKTLRQLLGWLESRPEVQVATCQRSTGLVK
VHYQEASRFPGAFALRVRDFAFTLHQLPPKPFQVEVLHALPGRVRLHVRGLEDDDILKLAAWAATLAGVHKASASPAIHS
LVVSFDPEMLNASQLMAALRTSDPSTWPAAPEPPRREWAATVFNSAVLAACVVNAAPMPVLAAGVALTSLPLAQRAFQSV
AERRITVDLLDLVAVGVSLATGQVRTAALITSLLGIGDLLIERSADRARSAISRLMRLEVLYAWRLRVDGEVEQVRADRL
KEGDLIVVHAGESVPADGTVVSGTAWVDEKALTGESEPRVREAGDRVLAASVVGEGSLRVRVVRAGVETTAAKILHILEG
AGAKPMTLQAKVDSVANGVVLPTFGLAAATWLWTREASRPISILITDFGTGVRIVVPASALVAMTLAARQGILIKGAQYL
ERLAQADTIVFDKTGTLTLGVPEVVDVIPVRGWDAREVLSLSAAAELRQSHPVAEAVRRHAQTQGVEVPQPEAGLEEFVL
GRGVCAQVNGRRVCVGSARWMQQQGVDVTDAGSALARSVPRDVATLWVTVDGALAGCISYVETLRPESAGVVQSLKENGR
RRIVLLSGDSPSRVAEVASRLGVDEAIAELLPEDKATQVRTLRRQGRIVAMVGDGINDAPALALADVGISLRGATDVALE
TADVVLLRGSLDDLLLAFDAGRDTLARVHLGLGLVLVPNAVAMVLAALGWLPPVAAAVVNNGSTVVAGFAALAPLFRQAR
AAQREDSTTH

Sequences:

>Translated_810_residues
MRAEVEFLSGMARGFKGRAHDVLDGHQRPVSVHVTDVAPGRLLIRGAAEDSKTLRQLLGWLESRPEVQVATCQRSTGLVK
VHYQEASRFPGAFALRVRDFAFTLHQLPPKPFQVEVLHALPGRVRLHVRGLEDDDILKLAAWAATLAGVHKASASPAIHS
LVVSFDPEMLNASQLMAALRTSDPSTWPAAPEPPRREWAATVFNSAVLAACVVNAAPMPVLAAGVALTSLPLAQRAFQSV
AERRITVDLLDLVAVGVSLATGQVRTAALITSLLGIGDLLIERSADRARSAISRLMRLEVLYAWRLRVDGEVEQVRADRL
KEGDLIVVHAGESVPADGTVVSGTAWVDEKALTGESEPRVREAGDRVLAASVVGEGSLRVRVVRAGVETTAAKILHILEG
AGAKPMTLQAKVDSVANGVVLPTFGLAAATWLWTREASRPISILITDFGTGVRIVVPASALVAMTLAARQGILIKGAQYL
ERLAQADTIVFDKTGTLTLGVPEVVDVIPVRGWDAREVLSLSAAAELRQSHPVAEAVRRHAQTQGVEVPQPEAGLEEFVL
GRGVCAQVNGRRVCVGSARWMQQQGVDVTDAGSALARSVPRDVATLWVTVDGALAGCISYVETLRPESAGVVQSLKENGR
RRIVLLSGDSPSRVAEVASRLGVDEAIAELLPEDKATQVRTLRRQGRIVAMVGDGINDAPALALADVGISLRGATDVALE
TADVVLLRGSLDDLLLAFDAGRDTLARVHLGLGLVLVPNAVAMVLAALGWLPPVAAAVVNNGSTVVAGFAALAPLFRQAR
AAQREDSTTH
>Mature_810_residues
MRAEVEFLSGMARGFKGRAHDVLDGHQRPVSVHVTDVAPGRLLIRGAAEDSKTLRQLLGWLESRPEVQVATCQRSTGLVK
VHYQEASRFPGAFALRVRDFAFTLHQLPPKPFQVEVLHALPGRVRLHVRGLEDDDILKLAAWAATLAGVHKASASPAIHS
LVVSFDPEMLNASQLMAALRTSDPSTWPAAPEPPRREWAATVFNSAVLAACVVNAAPMPVLAAGVALTSLPLAQRAFQSV
AERRITVDLLDLVAVGVSLATGQVRTAALITSLLGIGDLLIERSADRARSAISRLMRLEVLYAWRLRVDGEVEQVRADRL
KEGDLIVVHAGESVPADGTVVSGTAWVDEKALTGESEPRVREAGDRVLAASVVGEGSLRVRVVRAGVETTAAKILHILEG
AGAKPMTLQAKVDSVANGVVLPTFGLAAATWLWTREASRPISILITDFGTGVRIVVPASALVAMTLAARQGILIKGAQYL
ERLAQADTIVFDKTGTLTLGVPEVVDVIPVRGWDAREVLSLSAAAELRQSHPVAEAVRRHAQTQGVEVPQPEAGLEEFVL
GRGVCAQVNGRRVCVGSARWMQQQGVDVTDAGSALARSVPRDVATLWVTVDGALAGCISYVETLRPESAGVVQSLKENGR
RRIVLLSGDSPSRVAEVASRLGVDEAIAELLPEDKATQVRTLRRQGRIVAMVGDGINDAPALALADVGISLRGATDVALE
TADVVLLRGSLDDLLLAFDAGRDTLARVHLGLGLVLVPNAVAMVLAALGWLPPVAAAVVNNGSTVVAGFAALAPLFRQAR
AAQREDSTTH

Specific function: Involved In Copper Efflux. [C]

COG id: COG2217

COG function: function code P; Cation transport ATPase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily [H]

Homologues:

Organism=Homo sapiens, GI115529486, Length=599, Percent_Identity=27.212020033389, Blast_Score=218, Evalue=2e-56,
Organism=Homo sapiens, GI55743071, Length=632, Percent_Identity=26.8987341772152, Blast_Score=214, Evalue=2e-55,
Organism=Homo sapiens, GI55743073, Length=539, Percent_Identity=28.9424860853432, Blast_Score=212, Evalue=1e-54,
Organism=Homo sapiens, GI22748667, Length=209, Percent_Identity=28.7081339712919, Blast_Score=68, Evalue=3e-11,
Organism=Homo sapiens, GI4502271, Length=209, Percent_Identity=28.2296650717703, Blast_Score=67, Evalue=6e-11,
Organism=Homo sapiens, GI28373107, Length=196, Percent_Identity=27.5510204081633, Blast_Score=67, Evalue=9e-11,
Organism=Escherichia coli, GI1786691, Length=534, Percent_Identity=33.7078651685393, Blast_Score=227, Evalue=3e-60,
Organism=Escherichia coli, GI1789879, Length=563, Percent_Identity=34.9911190053286, Blast_Score=221, Evalue=1e-58,
Organism=Escherichia coli, GI1786914, Length=461, Percent_Identity=28.1995661605206, Blast_Score=132, Evalue=9e-32,
Organism=Escherichia coli, GI2367363, Length=644, Percent_Identity=24.8447204968944, Blast_Score=97, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17556548, Length=584, Percent_Identity=27.2260273972603, Blast_Score=182, Evalue=6e-46,
Organism=Caenorhabditis elegans, GI17559224, Length=213, Percent_Identity=29.5774647887324, Blast_Score=70, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6320475, Length=507, Percent_Identity=29.7830374753452, Blast_Score=200, Evalue=8e-52,
Organism=Saccharomyces cerevisiae, GI6319772, Length=642, Percent_Identity=26.4797507788162, Blast_Score=159, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6325221, Length=517, Percent_Identity=24.5647969052224, Blast_Score=111, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6321430, Length=518, Percent_Identity=24.1312741312741, Blast_Score=104, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6321271, Length=188, Percent_Identity=30.3191489361702, Blast_Score=85, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6321432, Length=96, Percent_Identity=39.5833333333333, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI221329854, Length=216, Percent_Identity=31.4814814814815, Blast_Score=113, Evalue=6e-25,
Organism=Drosophila melanogaster, GI281366676, Length=248, Percent_Identity=25, Blast_Score=67, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008250
- InterPro:   IPR006416
- InterPro:   IPR001757
- InterPro:   IPR018303
- InterPro:   IPR005834
- InterPro:   IPR023214 [H]

Pfam domain/function: PF00122 E1-E2_ATPase; PF00702 Hydrolase [H]

EC number: 3.6.3.4 [C]

Molecular weight: Translated: 85882; Mature: 85882

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: PS00154 ATPASE_E1_E2 ; PS01229 COF_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAEVEFLSGMARGFKGRAHDVLDGHQRPVSVHVTDVAPGRLLIRGAAEDSKTLRQLLGW
CCCHHHHHHHHHHCCCCCCCHHCCCCCCCEEEEEEECCCCEEEEEECCCHHHHHHHHHHH
LESRPEVQVATCQRSTGLVKVHYQEASRFPGAFALRVRDFAFTLHQLPPKPFQVEVLHAL
HHCCCCEEEEEECCCCCEEEEEECHHCCCCCEEEEEHHHHHHHHHHCCCCCCEEEEEECC
PGRVRLHVRGLEDDDILKLAAWAATLAGVHKASASPAIHSLVVSFDPEMLNASQLMAALR
CCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHEECCHHHCCHHHHHHHHH
TSDPSTWPAAPEPPRREWAATVFNSAVLAACVVNAAPMPVLAAGVALTSLPLAQRAFQSV
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
AERRITVDLLDLVAVGVSLATGQVRTAALITSLLGIGDLLIERSADRARSAISRLMRLEV
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
LYAWRLRVDGEVEQVRADRLKEGDLIVVHAGESVPADGTVVSGTAWVDEKALTGESEPRV
HHHEEEECCCHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEECCCEECCHHCCCCCCCCH
REAGDRVLAASVVGEGSLRVRVVRAGVETTAAKILHILEGAGAKPMTLQAKVDSVANGVV
HHCCCCEEEEEEECCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHCCEE
LPTFGLAAATWLWTREASRPISILITDFGTGVRIVVPASALVAMTLAARQGILIKGAQYL
ECCHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEECHHHHHHHHHHHHCCEEEECHHHH
ERLAQADTIVFDKTGTLTLGVPEVVDVIPVRGWDAREVLSLSAAAELRQSHPVAEAVRRH
HHHHHCCEEEEECCCCEEECCHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHH
AQTQGVEVPQPEAGLEEFVLGRGVCAQVNGRRVCVGSARWMQQQGVDVTDAGSALARSVP
HHHCCCCCCCCCCCHHHHHHCCCCEEECCCCEEEECCHHHHHHCCCCCCCCCHHHHHHCC
RDVATLWVTVDGALAGCISYVETLRPESAGVVQSLKENGRRRIVLLSGDSPSRVAEVASR
CCEEEEEEEECHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHH
LGVDEAIAELLPEDKATQVRTLRRQGRIVAMVGDGINDAPALALADVGISLRGATDVALE
CCHHHHHHHHCCCCHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHCCEEECCCCHHEEE
TADVVLLRGSLDDLLLAFDAGRDTLARVHLGLGLVLVPNAVAMVLAALGWLPPVAAAVVN
CCCEEEEECCHHHHHEEECCCCHHHHHHHHCCCEEEHHHHHHHHHHHHHCCCHHHHHHHC
NGSTVVAGFAALAPLFRQARAAQREDSTTH
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRAEVEFLSGMARGFKGRAHDVLDGHQRPVSVHVTDVAPGRLLIRGAAEDSKTLRQLLGW
CCCHHHHHHHHHHCCCCCCCHHCCCCCCCEEEEEEECCCCEEEEEECCCHHHHHHHHHHH
LESRPEVQVATCQRSTGLVKVHYQEASRFPGAFALRVRDFAFTLHQLPPKPFQVEVLHAL
HHCCCCEEEEEECCCCCEEEEEECHHCCCCCEEEEEHHHHHHHHHHCCCCCCEEEEEECC
PGRVRLHVRGLEDDDILKLAAWAATLAGVHKASASPAIHSLVVSFDPEMLNASQLMAALR
CCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHEECCHHHCCHHHHHHHHH
TSDPSTWPAAPEPPRREWAATVFNSAVLAACVVNAAPMPVLAAGVALTSLPLAQRAFQSV
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
AERRITVDLLDLVAVGVSLATGQVRTAALITSLLGIGDLLIERSADRARSAISRLMRLEV
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
LYAWRLRVDGEVEQVRADRLKEGDLIVVHAGESVPADGTVVSGTAWVDEKALTGESEPRV
HHHEEEECCCHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEECCCEECCHHCCCCCCCCH
REAGDRVLAASVVGEGSLRVRVVRAGVETTAAKILHILEGAGAKPMTLQAKVDSVANGVV
HHCCCCEEEEEEECCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHCCEE
LPTFGLAAATWLWTREASRPISILITDFGTGVRIVVPASALVAMTLAARQGILIKGAQYL
ECCHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEECHHHHHHHHHHHHCCEEEECHHHH
ERLAQADTIVFDKTGTLTLGVPEVVDVIPVRGWDAREVLSLSAAAELRQSHPVAEAVRRH
HHHHHCCEEEEECCCCEEECCHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHH
AQTQGVEVPQPEAGLEEFVLGRGVCAQVNGRRVCVGSARWMQQQGVDVTDAGSALARSVP
HHHCCCCCCCCCCCHHHHHHCCCCEEECCCCEEEECCHHHHHHCCCCCCCCCHHHHHHCC
RDVATLWVTVDGALAGCISYVETLRPESAGVVQSLKENGRRRIVLLSGDSPSRVAEVASR
CCEEEEEEEECHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHH
LGVDEAIAELLPEDKATQVRTLRRQGRIVAMVGDGINDAPALALADVGISLRGATDVALE
CCHHHHHHHHCCCCHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHCCEEECCCCHHEEE
TADVVLLRGSLDDLLLAFDAGRDTLARVHLGLGLVLVPNAVAMVLAALGWLPPVAAAVVN
CCCEEEEECCHHHHHEEECCCCHHHHHHHHCCCEEEHHHHHHHHHHHHHCCCHHHHHHHC
NGSTVVAGFAALAPLFRQARAAQREDSTTH
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Cu [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O [C]

Specific reaction: ATP + H2O = ADP + Orthophosphate. [C]

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]