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The map label for this gene is coaA

Identifier: 108763280

GI number: 108763280

Start: 2703373

End: 2704326

Strand: Direct

Name: coaA

Synonym: MXAN_2325

Alternate gene names: 108763280

Gene position: 2703373-2704326 (Clockwise)

Preceding gene: 108762734

Following gene: 108760972

Centisome position: 29.58

GC content: 67.19

Gene sequence:

>954_bases
ATGGCCTTAGCCACCGGTCTGTCCCCAGCCATGTTCATCGACCTGGAACGGGATGCCTGGCGGGCGCTGCGTGCCGCAAC
GCCTCTGCCGCTGAAGTCCGAGGACATTGACGGCCTGCGGGGCCTGGGAGAGCACCTCGACCTGGACGAGGTGGTGGACG
TCTACCTGCCCTTGTCCCGGTTGCTGAACCTGCAGGTGGCCGCGGCGCAGCGGCTGTGGGCGGAGCAGCAAGCCTTCCTG
GGAGGTTCGACGCAGAAGGTGCCGTACATCATCGCCATCGCCGGGAGCGTGGCGGTGGGCAAGAGCACGACGGCGCGCAT
CCTCCAGGCGCTGCTGAAGCGGTGGCCGGACCACCCGCGCGTGGAGTTGGTGACGACGGACGGGTTCCTTTTCCCCAACG
ACGTCCTCACCGAGCGCGACTTGATGAAGCGCAAGGGCTTCCCGGAGAGCTACGACCGGCGCGCCCTGGTGCGCTTCCTG
GCGGAGCTGAAGGCCGGACGCGCGGAGGTGGCGGCGCCGGTGTATTCGCACCTCGTCTACGACGTGGTGCCCGGTGAGGC
GCAGGTCGTCCGCCAGCCCGACATCCTCATCCTGGAAGGGCTCAACGTCCTCCAGGCCGGGGCACAGGAGGGGAAGCAGA
TGCCGGCGACGTTCCTCTCCGACTTCTTCGACTTCTCCATCTACGTGGACGCGCACGAGCACGACATCCGCCGCTGGTAC
GTCAACCGTTTCCTCAAGCTCCAGCAGACGGCGTTTCGCGACGAGCGCAGCTACTTCCGCCGGTTCTCCGAGCTGAACCA
CGAGCAGGCGATTCAGCTCGCCGAGTCGGTGTGGGGCGAAATCAACGGGCCCAACCTGGCCCAGAACATCGCGCCCACCC
GTTCGCGCGCGCGCCTCATCCTCCTCAAGGGCCCCGACCACAAGGTGAAGCGGGTGAGGCTGCGCAAGCTGTAG

Upstream 100 bases:

>100_bases
CTACGGGTGGGATCCCGCGGCTGGCACCTGAACGTCCGAGCGTGAACGTCTCGGCTGTGCTACGCGGCGGCTTGGATGTT
CAGCTCCTGGAGTGGAATCC

Downstream 100 bases:

>100_bases
CCGCGCGTCAGAAGCGCAGGCGGTAGTGGAGCGCTTTGGGTCGCGTCAGGGCGTCGAAGCCCAGCGCGCTCAGCGTCACG
CCGCGTCCGGAGTCCTTCAC

Product: pantothenate kinase

Products: NA

Alternate protein names: Pantothenic acid kinase

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MALATGLSPAMFIDLERDAWRALRAATPLPLKSEDIDGLRGLGEHLDLDEVVDVYLPLSRLLNLQVAAAQRLWAEQQAFL
GGSTQKVPYIIAIAGSVAVGKSTTARILQALLKRWPDHPRVELVTTDGFLFPNDVLTERDLMKRKGFPESYDRRALVRFL
AELKAGRAEVAAPVYSHLVYDVVPGEAQVVRQPDILILEGLNVLQAGAQEGKQMPATFLSDFFDFSIYVDAHEHDIRRWY
VNRFLKLQQTAFRDERSYFRRFSELNHEQAIQLAESVWGEINGPNLAQNIAPTRSRARLILLKGPDHKVKRVRLRKL

Sequences:

>Translated_317_residues
MALATGLSPAMFIDLERDAWRALRAATPLPLKSEDIDGLRGLGEHLDLDEVVDVYLPLSRLLNLQVAAAQRLWAEQQAFL
GGSTQKVPYIIAIAGSVAVGKSTTARILQALLKRWPDHPRVELVTTDGFLFPNDVLTERDLMKRKGFPESYDRRALVRFL
AELKAGRAEVAAPVYSHLVYDVVPGEAQVVRQPDILILEGLNVLQAGAQEGKQMPATFLSDFFDFSIYVDAHEHDIRRWY
VNRFLKLQQTAFRDERSYFRRFSELNHEQAIQLAESVWGEINGPNLAQNIAPTRSRARLILLKGPDHKVKRVRLRKL
>Mature_316_residues
ALATGLSPAMFIDLERDAWRALRAATPLPLKSEDIDGLRGLGEHLDLDEVVDVYLPLSRLLNLQVAAAQRLWAEQQAFLG
GSTQKVPYIIAIAGSVAVGKSTTARILQALLKRWPDHPRVELVTTDGFLFPNDVLTERDLMKRKGFPESYDRRALVRFLA
ELKAGRAEVAAPVYSHLVYDVVPGEAQVVRQPDILILEGLNVLQAGAQEGKQMPATFLSDFFDFSIYVDAHEHDIRRWYV
NRFLKLQQTAFRDERSYFRRFSELNHEQAIQLAESVWGEINGPNLAQNIAPTRSRARLILLKGPDHKVKRVRLRKL

Specific function: Coenzyme A (CoA) biosynthesis; first step. [C]

COG id: COG1072

COG function: function code H; Panthothenate kinase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic pantothenate kinase family

Homologues:

Organism=Escherichia coli, GI1790409, Length=305, Percent_Identity=57.0491803278689, Blast_Score=358, Evalue=1e-100,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAA_MYXXD (Q1D9X8)

Other databases:

- EMBL:   CP000113
- RefSeq:   YP_630545.1
- ProteinModelPortal:   Q1D9X8
- SMR:   Q1D9X8
- STRING:   Q1D9X8
- GeneID:   4107035
- GenomeReviews:   CP000113_GR
- KEGG:   mxa:MXAN_2325
- TIGR:   MXAN_2325
- eggNOG:   COG1072
- HOGENOM:   HBG732538
- OMA:   GLNVLQP
- PhylomeDB:   Q1D9X8
- ProtClustDB:   PRK05439
- BioCyc:   MXAN246197:MXAN_2325-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00215
- InterPro:   IPR004566
- InterPro:   IPR006083
- PANTHER:   PTHR10285:SF7
- PIRSF:   PIRSF000545
- TIGRFAMs:   TIGR00554

Pfam domain/function: PF00485 PRK

EC number: =2.7.1.33

Molecular weight: Translated: 35872; Mature: 35741

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALATGLSPAMFIDLERDAWRALRAATPLPLKSEDIDGLRGLGEHLDLDEVVDVYLPLSR
CCCCCCCCCEEEEEECHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHH
LLNLQVAAAQRLWAEQQAFLGGSTQKVPYIIAIAGSVAVGKSTTARILQALLKRWPDHPR
HHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCC
VELVTTDGFLFPNDVLTERDLMKRKGFPESYDRRALVRFLAELKAGRAEVAAPVYSHLVY
EEEEEECCEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
DVVPGEAQVVRQPDILILEGLNVLQAGAQEGKQMPATFLSDFFDFSIYVDAHEHDIRRWY
HCCCCCHHEECCCCEEEECCCHHHHHHHHCCCCCCHHHHHHHHCEEEEEECCHHHHHHHH
VNRFLKLQQTAFRDERSYFRRFSELNHEQAIQLAESVWGEINGPNLAQNIAPTRSRARLI
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCEEE
LLKGPDHKVKRVRLRKL
EEECCCHHHHHHHHHCC
>Mature Secondary Structure 
ALATGLSPAMFIDLERDAWRALRAATPLPLKSEDIDGLRGLGEHLDLDEVVDVYLPLSR
CCCCCCCCEEEEEECHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHH
LLNLQVAAAQRLWAEQQAFLGGSTQKVPYIIAIAGSVAVGKSTTARILQALLKRWPDHPR
HHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCC
VELVTTDGFLFPNDVLTERDLMKRKGFPESYDRRALVRFLAELKAGRAEVAAPVYSHLVY
EEEEEECCEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
DVVPGEAQVVRQPDILILEGLNVLQAGAQEGKQMPATFLSDFFDFSIYVDAHEHDIRRWY
HCCCCCHHEECCCCEEEECCCHHHHHHHHCCCCCCHHHHHHHHCEEEEEECCHHHHHHHH
VNRFLKLQQTAFRDERSYFRRFSELNHEQAIQLAESVWGEINGPNLAQNIAPTRSRARLI
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCEEE
LLKGPDHKVKRVRLRKL
EEECCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA