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The map label for this gene is tlpB [H]

Identifier: 108763249

GI number: 108763249

Start: 2588941

End: 2591130

Strand: Reverse

Name: tlpB [H]

Synonym: MXAN_2244

Alternate gene names: 108763249

Gene position: 2591130-2588941 (Counterclockwise)

Preceding gene: 108762459

Following gene: 108760829

Centisome position: 28.35

GC content: 68.36

Gene sequence:

>2190_bases
ATGGACGCATCCATGCGTCACATCCGCATTCCGACTCACGCGCCGGCGACTCACGCGCCGGCGACTCACGCAGTCTCCGG
TGTTTCACCTGTCTCACCTTCCGGCGCATGCATGTCTTCACGACGCACGTCGTGGTGCTGGGTGCTGCCGTTCCTCCTGA
TACTTTCCACCTCCGCGTGGGCGGACACAGGACGGCCCAGCATCGACTTGAATCAGGGCTGGCGATACCGCTGGGGAGAC
TCACCGCCGGGCCCCGCCGATGTACCAGCCTGGGCACTGGAGTCCGGGGATGAGCAGGCGTGGCAGCCCGTGGCAGCCCT
CCGCGAGCCGCCGGGCCGGGGAGCGCACACCGTCCTCTGGCTGAGCCTCCCCGTCCCCCAGGGGCAGTGGCTGGAGCCCG
CGCTCTACCTGGGCACGGTGGCCAATGCCTTCGAGGTCTACGCCAACGGCCACCGCATCCATGCGAGCGGACGGCTGAAT
CCCTCGGGCCAGGAGGAGACGGACAACCTCGCGTGGCGGCTCATCCCCCTGCCACCCACGGTGGAAGGCTCACGCCTGCT
GCTGCGAATCCAGAGCAGCGGTCCAATCATCGGCGTGGGAGGCGCGGCTCGGGTGGGGGCACACCATCAGCTCCTCGCGA
CGGTGACGCGCACGGGGCTGGCGCCCTTCGTCATGGGCATGCTGCTGCTCACCATCGCCAGTGCCGCCGCCTTGGGTGCC
CTGGTACGGCGTCAGACGCAGATGCTCCTGCCGCTCGTCATCTTCACGAGCGGCTCGGCGGCCCTGCTTCTGGGCACGAG
CGGCCTGATTCCTGCGCTCTGGGGCCGCTATCTGCTGGGGAGCCAGCTCACGCTGGTGGGCTCGCACTGCATCCTGCCCG
CGCTCGCCTGGTTCATCTCCGACAGCGTCCTGGAGAACCGGATGCGCTGGTTCCGCTGGAGCGCCTGGGCCGCGTGCGTG
CCGGCCTCCCTTCAAGTCATCATCGTGATGGCCGACCTGGGCATGGCGCAGCGGAACCTTGGCCTCTTCGTCCTCTACTC
GGTGCCTTGCCTGCTCGGGTGCGTCATCGTCGCGGGAATCTCAGCGTGGCGGGGCAACCCCGACGCGCGAATCTTCTCCA
TGGGCCTGGGCGTGTTCTTCGGTGTCGTCATCCACACCACGCTGCCGGTGTTCGGGCTGGCGGAGGCCACGGACTCCCTC
ATGCACTGGGGCTTCCTGGCGCTCACGCTCTCATTGGTGGGCATCGTCGTGCGCCGCTCGGTGCTGGTGGTGCGCGCGCT
CGCGTCGCACACGCACCAGCTCGAGGAGCGTCGTCATGAAGTGAAGCGGCTCGCCCAGGACATGGGGAGCGGCGCTGGCG
AGCTGGCCACGGTGGCGCAACAACTGCGCACGTCCAGTGAGGTTCAGACAGCGGGGGTCAGCCGACAGGCCGCGGCGCTC
CGCGAGGCGGAGCAGACGGTCCAGGAAATCCGGCAGGGCTCCCTGGTGACGGCGAACAAGGCGCGGCAGCTCGCGGGCTC
CATCGAAACCGCCGAGGAGGCGGGGCGCGATGGCGGCGCGGCCATCACCCACACGTTGACCAATCTGGAAGCCATCCGCC
AGGAGGTCTCCGAGATGTCGAGCCACATCCTCGCGCTGGACGCACGCACCCGCGAAATCTCCAGCATCGTGGACACCGTG
AAGGGACTTGCGGACCAGTCCAACATGCTGGCCATCAACGCCGCCATCGAAGCCGCGCGCAGCGGGGAGCACGGCCGGGG
CTTCGGCGTCGTGTCGCGAGAGGTCCGCAGCCTCGCCGACCAGTCCATCCTGGCGACCCATCGCATCCGCGAGGTGCTCG
ACGGTGTGAGTCTGAGCATGCGTGAGGCCGCGAAGAGGAGTGAACAGGGAGAGCAACGCGTGAAGGCGAGCCTGGACGCG
GTGCGCGTCTCCGGCACCCAGCTCCAGCGGCTCACGGGCATCATCGACGACACCGGCACCAATGTGCGGCAGATTTCCGC
GGCGGTGGCGCAGCAGGACGCGGGCACCTCCCAGATTGCCCAGGCCATTCAAGAATTGTCCGCCCAGATGCGGCATACGC
TGCGCACCGCCGAGGAGACTCAGAAGGTGTCGGGTTCGGTGCAAGCGCTGGCGGAGAACATGGCGGGCACGGCCCGCATC
GCGCTCCAGACGGGAACACTCGATGACTGA

Upstream 100 bases:

>100_bases
CAAGTATCACCGCCTGTCGATGAAACACATACGGACAGAGGTCGAGCGCCGGGCGGGGTGAAGCAGACCCATTTTACACG
GACGCCTCCCGCCCCCGAGG

Downstream 100 bases:

>100_bases
GCCGCGTCCCGTGACGTCCGCGCCGTGACGGATGGGAGCGCATCGGTTGCAGGTCCGCGCAAAGGGTGCTCAGAAGCCAC
CATGGCGCAGAACATCTACG

Product: putative methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 729; Mature: 729

Protein sequence:

>729_residues
MDASMRHIRIPTHAPATHAPATHAVSGVSPVSPSGACMSSRRTSWCWVLPFLLILSTSAWADTGRPSIDLNQGWRYRWGD
SPPGPADVPAWALESGDEQAWQPVAALREPPGRGAHTVLWLSLPVPQGQWLEPALYLGTVANAFEVYANGHRIHASGRLN
PSGQEETDNLAWRLIPLPPTVEGSRLLLRIQSSGPIIGVGGAARVGAHHQLLATVTRTGLAPFVMGMLLLTIASAAALGA
LVRRQTQMLLPLVIFTSGSAALLLGTSGLIPALWGRYLLGSQLTLVGSHCILPALAWFISDSVLENRMRWFRWSAWAACV
PASLQVIIVMADLGMAQRNLGLFVLYSVPCLLGCVIVAGISAWRGNPDARIFSMGLGVFFGVVIHTTLPVFGLAEATDSL
MHWGFLALTLSLVGIVVRRSVLVVRALASHTHQLEERRHEVKRLAQDMGSGAGELATVAQQLRTSSEVQTAGVSRQAAAL
REAEQTVQEIRQGSLVTANKARQLAGSIETAEEAGRDGGAAITHTLTNLEAIRQEVSEMSSHILALDARTREISSIVDTV
KGLADQSNMLAINAAIEAARSGEHGRGFGVVSREVRSLADQSILATHRIREVLDGVSLSMREAAKRSEQGEQRVKASLDA
VRVSGTQLQRLTGIIDDTGTNVRQISAAVAQQDAGTSQIAQAIQELSAQMRHTLRTAEETQKVSGSVQALAENMAGTARI
ALQTGTLDD

Sequences:

>Translated_729_residues
MDASMRHIRIPTHAPATHAPATHAVSGVSPVSPSGACMSSRRTSWCWVLPFLLILSTSAWADTGRPSIDLNQGWRYRWGD
SPPGPADVPAWALESGDEQAWQPVAALREPPGRGAHTVLWLSLPVPQGQWLEPALYLGTVANAFEVYANGHRIHASGRLN
PSGQEETDNLAWRLIPLPPTVEGSRLLLRIQSSGPIIGVGGAARVGAHHQLLATVTRTGLAPFVMGMLLLTIASAAALGA
LVRRQTQMLLPLVIFTSGSAALLLGTSGLIPALWGRYLLGSQLTLVGSHCILPALAWFISDSVLENRMRWFRWSAWAACV
PASLQVIIVMADLGMAQRNLGLFVLYSVPCLLGCVIVAGISAWRGNPDARIFSMGLGVFFGVVIHTTLPVFGLAEATDSL
MHWGFLALTLSLVGIVVRRSVLVVRALASHTHQLEERRHEVKRLAQDMGSGAGELATVAQQLRTSSEVQTAGVSRQAAAL
REAEQTVQEIRQGSLVTANKARQLAGSIETAEEAGRDGGAAITHTLTNLEAIRQEVSEMSSHILALDARTREISSIVDTV
KGLADQSNMLAINAAIEAARSGEHGRGFGVVSREVRSLADQSILATHRIREVLDGVSLSMREAAKRSEQGEQRVKASLDA
VRVSGTQLQRLTGIIDDTGTNVRQISAAVAQQDAGTSQIAQAIQELSAQMRHTLRTAEETQKVSGSVQALAENMAGTARI
ALQTGTLDD
>Mature_729_residues
MDASMRHIRIPTHAPATHAPATHAVSGVSPVSPSGACMSSRRTSWCWVLPFLLILSTSAWADTGRPSIDLNQGWRYRWGD
SPPGPADVPAWALESGDEQAWQPVAALREPPGRGAHTVLWLSLPVPQGQWLEPALYLGTVANAFEVYANGHRIHASGRLN
PSGQEETDNLAWRLIPLPPTVEGSRLLLRIQSSGPIIGVGGAARVGAHHQLLATVTRTGLAPFVMGMLLLTIASAAALGA
LVRRQTQMLLPLVIFTSGSAALLLGTSGLIPALWGRYLLGSQLTLVGSHCILPALAWFISDSVLENRMRWFRWSAWAACV
PASLQVIIVMADLGMAQRNLGLFVLYSVPCLLGCVIVAGISAWRGNPDARIFSMGLGVFFGVVIHTTLPVFGLAEATDSL
MHWGFLALTLSLVGIVVRRSVLVVRALASHTHQLEERRHEVKRLAQDMGSGAGELATVAQQLRTSSEVQTAGVSRQAAAL
REAEQTVQEIRQGSLVTANKARQLAGSIETAEEAGRDGGAAITHTLTNLEAIRQEVSEMSSHILALDARTREISSIVDTV
KGLADQSNMLAINAAIEAARSGEHGRGFGVVSREVRSLADQSILATHRIREVLDGVSLSMREAAKRSEQGEQRVKASLDA
VRVSGTQLQRLTGIIDDTGTNVRQISAAVAQQDAGTSQIAQAIQELSAQMRHTLRTAEETQKVSGSVQALAENMAGTARI
ALQTGTLDD

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=253, Percent_Identity=30.0395256916996, Blast_Score=90, Evalue=6e-19,
Organism=Escherichia coli, GI1789453, Length=268, Percent_Identity=26.4925373134328, Blast_Score=87, Evalue=5e-18,
Organism=Escherichia coli, GI2367378, Length=246, Percent_Identity=28.0487804878049, Blast_Score=84, Evalue=5e-17,
Organism=Escherichia coli, GI1787690, Length=252, Percent_Identity=28.5714285714286, Blast_Score=81, Evalue=3e-16,
Organism=Escherichia coli, GI1788195, Length=237, Percent_Identity=27.0042194092827, Blast_Score=80, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR003122
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR022094 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF12332 McpA_N; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 77877; Mature: 77877

Theoretical pI: Translated: 7.98; Mature: 7.98

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDASMRHIRIPTHAPATHAPATHAVSGVSPVSPSGACMSSRRTSWCWVLPFLLILSTSAW
CCCCCCEEECCCCCCCCCCCCHHHCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHCCCCC
ADTGRPSIDLNQGWRYRWGDSPPGPADVPAWALESGDEQAWQPVAALREPPGRGAHTVLW
CCCCCCCEECCCCCCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHCCCCCCCCEEEEE
LSLPVPQGQWLEPALYLGTVANAFEVYANGHRIHASGRLNPSGQEETDNLAWRLIPLPPT
EEECCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCEEEEEECCCC
VEGSRLLLRIQSSGPIIGVGGAARVGAHHQLLATVTRTGLAPFVMGMLLLTIASAAALGA
CCCCEEEEEEECCCCEEECCCCHHHCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
LVRRQTQMLLPLVIFTSGSAALLLGTSGLIPALWGRYLLGSQLTLVGSHCILPALAWFIS
HHHHHHHHHHHEEEEECCCEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
DSVLENRMRWFRWSAWAACVPASLQVIIVMADLGMAQRNLGLFVLYSVPCLLGCVIVAGI
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHCCCEEHHHHHHHHHHHHHHHHH
SAWRGNPDARIFSMGLGVFFGVVIHTTLPVFGLAEATDSLMHWGFLALTLSLVGIVVRRS
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLVVRALASHTHQLEERRHEVKRLAQDMGSGAGELATVAQQLRTSSEVQTAGVSRQAAAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHH
REAEQTVQEIRQGSLVTANKARQLAGSIETAEEAGRDGGAAITHTLTNLEAIRQEVSEMS
HHHHHHHHHHHCCCCEEHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
SHILALDARTREISSIVDTVKGLADQSNMLAINAAIEAARSGEHGRGFGVVSREVRSLAD
HHEEEECHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHCCCCCCCCHHHHHHHHHHHH
QSILATHRIREVLDGVSLSMREAAKRSEQGEQRVKASLDAVRVSGTQLQRLTGIIDDTGT
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCC
NVRQISAAVAQQDAGTSQIAQAIQELSAQMRHTLRTAEETQKVSGSVQALAENMAGTARI
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
ALQTGTLDD
EEECCCCCC
>Mature Secondary Structure
MDASMRHIRIPTHAPATHAPATHAVSGVSPVSPSGACMSSRRTSWCWVLPFLLILSTSAW
CCCCCCEEECCCCCCCCCCCCHHHCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHCCCCC
ADTGRPSIDLNQGWRYRWGDSPPGPADVPAWALESGDEQAWQPVAALREPPGRGAHTVLW
CCCCCCCEECCCCCCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHCCCCCCCCEEEEE
LSLPVPQGQWLEPALYLGTVANAFEVYANGHRIHASGRLNPSGQEETDNLAWRLIPLPPT
EEECCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCEEEEEECCCC
VEGSRLLLRIQSSGPIIGVGGAARVGAHHQLLATVTRTGLAPFVMGMLLLTIASAAALGA
CCCCEEEEEEECCCCEEECCCCHHHCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
LVRRQTQMLLPLVIFTSGSAALLLGTSGLIPALWGRYLLGSQLTLVGSHCILPALAWFIS
HHHHHHHHHHHEEEEECCCEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
DSVLENRMRWFRWSAWAACVPASLQVIIVMADLGMAQRNLGLFVLYSVPCLLGCVIVAGI
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHCCCEEHHHHHHHHHHHHHHHHH
SAWRGNPDARIFSMGLGVFFGVVIHTTLPVFGLAEATDSLMHWGFLALTLSLVGIVVRRS
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLVVRALASHTHQLEERRHEVKRLAQDMGSGAGELATVAQQLRTSSEVQTAGVSRQAAAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHH
REAEQTVQEIRQGSLVTANKARQLAGSIETAEEAGRDGGAAITHTLTNLEAIRQEVSEMS
HHHHHHHHHHHCCCCEEHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
SHILALDARTREISSIVDTVKGLADQSNMLAINAAIEAARSGEHGRGFGVVSREVRSLAD
HHEEEECHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHCCCCCCCCHHHHHHHHHHHH
QSILATHRIREVLDGVSLSMREAAKRSEQGEQRVKASLDAVRVSGTQLQRLTGIIDDTGT
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCC
NVRQISAAVAQQDAGTSQIAQAIQELSAQMRHTLRTAEETQKVSGSVQALAENMAGTARI
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
ALQTGTLDD
EEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8188684; 9384377 [H]