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The map label for this gene is degP [H]

Identifier: 108763173

GI number: 108763173

Start: 5328127

End: 5329560

Strand: Reverse

Name: degP [H]

Synonym: MXAN_4330

Alternate gene names: 108763173

Gene position: 5329560-5328127 (Counterclockwise)

Preceding gene: 108761636

Following gene: 108760519

Centisome position: 58.31

GC content: 71.69

Gene sequence:

>1434_bases
GTGTTCTCCCGATTCTTCTCCCTGTGTTTGGTGCTGGCGCTCGCCCCGGTCGCGGCGGCCGCCGAGGGTCCTCTCGACGC
GTGGCTTTCCGCGCGGGCCCGGGAGCATGCTGCGTGGTTCGCCGCGCAGGCCGCCGGTGTCGAGGGGCAGACGGGCAGCC
TGGGCCTGTGGCGCGAGCGCGCCGAGGGAGACCCGGGCATCCCCCACTTCGTGCCCCCGTCCTCGCTGGCGCCGCTGATC
CGCGCGGTGGAGGCGAGCGTCGTCAACATCACCACCGTGGGGCCCCGGGCCGGTGGCCTGGAGGGGATGAAGAAGTCCAC
CGGCTCCGGCTTCGTGCTGACGCCCGACGGGCTCGTCGTCACCAACAACCACGTGGTGGCCAGCGCGCAGCAGATTGCCG
TGCGTCTGGCGGATGGCCGCGAGTTCGCCGCTTCCGTGGTGGGCCGTGACGCCTCCACGGACGTGGCGCTGCTGCGGCTC
AGTGGCGTGGACCTGGGTAAGCTGCCCGCCGTCTACCTGGGGGACTCGGACCGGATGGCGGTGGGCGACTGGGTGGTGGC
CATAGGCAACCCCTTTGGCCTGGACCACTCCGTGTCCCACGGGATGATCTCCGCCAAGGAGCGCGTCCTGGGCGTGGGCC
AGTTCGACGACTTCATCCAGACGGACGCGCTCATCAACCCCGGCAACTCCGGTGGGCCGCTCTTCAACATGAAGGGGGAG
GTGGTGGGGGTGAACACCGCCATCATCAGTCAGGGGCAGGGCATTGGTTTCGCGGTCCCCAGCAACCTGGTGAAGGAGCT
GCTGCCCAACCTCCGGGAGAACGGCAAGCTGGCGCGTGGGTGGCTGGGCGTCGTCATCAATGACGACGGGAGCAATGGGG
GCGGTGAGCGCCAGGCCCCGCTGGTGAAGGACGTCTACAAGGGCAGCCCGGCCGCGGCCGTGGGCATCCGCCCGGGAGAC
CGGCTGGTGGCGGTGAACGGGCGGCCCATCGGCTCCTACCTGCAGTTGTTGCGCAAGGTGGCGCTGCTGGCGCCGGGCAC
CGAGGCGCGCCTGTCGCTGACGCGGGGCACTGAGACGCAGGAAGTGACGGTGCGGCTGGTGGCGCGCCCCGCGCAGGAGG
CCACCGAGGGGCTCATCCAGCGGACGGCCAGCGAGGAGGAGATGGGGCTGGTGATCCGTGACCTCACACCGGAGGTGGCC
GCGCCCCTGGGGGAGACGGCCTGGTCCGGCGTGCTGGTGTCGGGTGTCACGCCGCGCAGCCCGGCGGACTCGGCCGGCCT
GCGGGCGGGAGACGTCGTGACGGAAGTGAACCGCCGCCGGGTGAAGGACGTGGCTGGGGTGCGCGCGGCGCTGGGGAAGG
GGAGCGCCGGGGTCAGCATCCTCCTGCGGGTGAAGCGGGGCGAGGCGCTCCAGTACATCGCCATCGCCCGGTGA

Upstream 100 bases:

>100_bases
ACGCCGCCGTCCAGGGCGCCCCCGTCACTCACGGGAAGGGGGCGCCGGGCCAGGCTGTTGAGTCCGCTCGACCCTGGTCC
GCCGTGTAGACTGCCGCTCC

Downstream 100 bases:

>100_bases
GGTGACGCCCGGTTAGCGCTTCTTGGCGTCCTTGCCGTGGAGCCACAGGCCCATGGCCTGGCCGCTGCGACCCTCCGTGA
TGAAGATGGCTTCGATGCGC

Product: periplasmic serine protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 477; Mature: 477

Protein sequence:

>477_residues
MFSRFFSLCLVLALAPVAAAAEGPLDAWLSARAREHAAWFAAQAAGVEGQTGSLGLWRERAEGDPGIPHFVPPSSLAPLI
RAVEASVVNITTVGPRAGGLEGMKKSTGSGFVLTPDGLVVTNNHVVASAQQIAVRLADGREFAASVVGRDASTDVALLRL
SGVDLGKLPAVYLGDSDRMAVGDWVVAIGNPFGLDHSVSHGMISAKERVLGVGQFDDFIQTDALINPGNSGGPLFNMKGE
VVGVNTAIISQGQGIGFAVPSNLVKELLPNLRENGKLARGWLGVVINDDGSNGGGERQAPLVKDVYKGSPAAAVGIRPGD
RLVAVNGRPIGSYLQLLRKVALLAPGTEARLSLTRGTETQEVTVRLVARPAQEATEGLIQRTASEEEMGLVIRDLTPEVA
APLGETAWSGVLVSGVTPRSPADSAGLRAGDVVTEVNRRRVKDVAGVRAALGKGSAGVSILLRVKRGEALQYIAIAR

Sequences:

>Translated_477_residues
MFSRFFSLCLVLALAPVAAAAEGPLDAWLSARAREHAAWFAAQAAGVEGQTGSLGLWRERAEGDPGIPHFVPPSSLAPLI
RAVEASVVNITTVGPRAGGLEGMKKSTGSGFVLTPDGLVVTNNHVVASAQQIAVRLADGREFAASVVGRDASTDVALLRL
SGVDLGKLPAVYLGDSDRMAVGDWVVAIGNPFGLDHSVSHGMISAKERVLGVGQFDDFIQTDALINPGNSGGPLFNMKGE
VVGVNTAIISQGQGIGFAVPSNLVKELLPNLRENGKLARGWLGVVINDDGSNGGGERQAPLVKDVYKGSPAAAVGIRPGD
RLVAVNGRPIGSYLQLLRKVALLAPGTEARLSLTRGTETQEVTVRLVARPAQEATEGLIQRTASEEEMGLVIRDLTPEVA
APLGETAWSGVLVSGVTPRSPADSAGLRAGDVVTEVNRRRVKDVAGVRAALGKGSAGVSILLRVKRGEALQYIAIAR
>Mature_477_residues
MFSRFFSLCLVLALAPVAAAAEGPLDAWLSARAREHAAWFAAQAAGVEGQTGSLGLWRERAEGDPGIPHFVPPSSLAPLI
RAVEASVVNITTVGPRAGGLEGMKKSTGSGFVLTPDGLVVTNNHVVASAQQIAVRLADGREFAASVVGRDASTDVALLRL
SGVDLGKLPAVYLGDSDRMAVGDWVVAIGNPFGLDHSVSHGMISAKERVLGVGQFDDFIQTDALINPGNSGGPLFNMKGE
VVGVNTAIISQGQGIGFAVPSNLVKELLPNLRENGKLARGWLGVVINDDGSNGGGERQAPLVKDVYKGSPAAAVGIRPGD
RLVAVNGRPIGSYLQLLRKVALLAPGTEARLSLTRGTETQEVTVRLVARPAQEATEGLIQRTASEEEMGLVIRDLTPEVA
APLGETAWSGVLVSGVTPRSPADSAGLRAGDVVTEVNRRRVKDVAGVRAALGKGSAGVSILLRVKRGEALQYIAIAR

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=247, Percent_Identity=36.4372469635627, Blast_Score=151, Evalue=1e-36,
Organism=Homo sapiens, GI22129776, Length=265, Percent_Identity=35.8490566037736, Blast_Score=145, Evalue=7e-35,
Organism=Homo sapiens, GI24308541, Length=333, Percent_Identity=32.1321321321321, Blast_Score=139, Evalue=7e-33,
Organism=Homo sapiens, GI7019477, Length=241, Percent_Identity=38.1742738589212, Blast_Score=130, Evalue=3e-30,
Organism=Escherichia coli, GI1789629, Length=441, Percent_Identity=34.9206349206349, Blast_Score=217, Evalue=1e-57,
Organism=Escherichia coli, GI1786356, Length=380, Percent_Identity=36.8421052631579, Blast_Score=216, Evalue=3e-57,
Organism=Escherichia coli, GI1789630, Length=312, Percent_Identity=33.974358974359, Blast_Score=160, Evalue=1e-40,
Organism=Drosophila melanogaster, GI24646839, Length=286, Percent_Identity=32.5174825174825, Blast_Score=132, Evalue=5e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.-

Molecular weight: Translated: 49541; Mature: 49541

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSRFFSLCLVLALAPVAAAAEGPLDAWLSARAREHAAWFAAQAAGVEGQTGSLGLWRER
CHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
AEGDPGIPHFVPPSSLAPLIRAVEASVVNITTVGPRAGGLEGMKKSTGSGFVLTPDGLVV
CCCCCCCCCCCCCHHHHHHHHHHHCCEEEEEECCCCCCCCCCHHHCCCCCEEECCCCEEE
TNNHVVASAQQIAVRLADGREFAASVVGRDASTDVALLRLSGVDLGKLPAVYLGDSDRMA
ECCEEEECHHHEEEEECCCHHHHHHHHCCCCCCCEEEEEECCCCCCCCCEEEECCCCCEE
VGDWVVAIGNPFGLDHSVSHGMISAKERVLGVGQFDDFIQTDALINPGNSGGPLFNMKGE
ECCEEEEECCCCCCCCCCCCCHHHHHHHHEECCCHHHHHHHCCEECCCCCCCCEEECCCC
VVGVNTAIISQGQGIGFAVPSNLVKELLPNLRENGKLARGWLGVVINDDGSNGGGERQAP
EEEEEHHEEECCCCCEEECCHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCCCCCCCCC
LVKDVYKGSPAAAVGIRPGDRLVAVNGRPIGSYLQLLRKVALLAPGTEARLSLTRGTETQ
HHHHHHCCCCCEEEECCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCH
EVTVRLVARPAQEATEGLIQRTASEEEMGLVIRDLTPEVAAPLGETAWSGVLVSGVTPRS
HEEEEEEECCHHHHHHHHHHHHCCCHHHCEEEECCCHHHHCCCCCHHHCCEEEECCCCCC
PADSAGLRAGDVVTEVNRRRVKDVAGVRAALGKGSAGVSILLRVKRGEALQYIAIAR
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCEEEEEECC
>Mature Secondary Structure
MFSRFFSLCLVLALAPVAAAAEGPLDAWLSARAREHAAWFAAQAAGVEGQTGSLGLWRER
CHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
AEGDPGIPHFVPPSSLAPLIRAVEASVVNITTVGPRAGGLEGMKKSTGSGFVLTPDGLVV
CCCCCCCCCCCCCHHHHHHHHHHHCCEEEEEECCCCCCCCCCHHHCCCCCEEECCCCEEE
TNNHVVASAQQIAVRLADGREFAASVVGRDASTDVALLRLSGVDLGKLPAVYLGDSDRMA
ECCEEEECHHHEEEEECCCHHHHHHHHCCCCCCCEEEEEECCCCCCCCCEEEECCCCCEE
VGDWVVAIGNPFGLDHSVSHGMISAKERVLGVGQFDDFIQTDALINPGNSGGPLFNMKGE
ECCEEEEECCCCCCCCCCCCCHHHHHHHHEECCCHHHHHHHCCEECCCCCCCCEEECCCC
VVGVNTAIISQGQGIGFAVPSNLVKELLPNLRENGKLARGWLGVVINDDGSNGGGERQAP
EEEEEHHEEECCCCCEEECCHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCCCCCCCCC
LVKDVYKGSPAAAVGIRPGDRLVAVNGRPIGSYLQLLRKVALLAPGTEARLSLTRGTETQ
HHHHHHCCCCCEEEECCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCH
EVTVRLVARPAQEATEGLIQRTASEEEMGLVIRDLTPEVAAPLGETAWSGVLVSGVTPRS
HEEEEEEECCHHHHHHHHHHHHCCCHHHCEEEECCCHHHHCCCCCHHHCCEEEECCCCCC
PADSAGLRAGDVVTEVNRRRVKDVAGVRAALGKGSAGVSILLRVKRGEALQYIAIAR
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10684935 [H]