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The map label for this gene is dinB [H]

Identifier: 108763124

GI number: 108763124

Start: 2963523

End: 2964743

Strand: Reverse

Name: dinB [H]

Synonym: MXAN_2546

Alternate gene names: 108763124

Gene position: 2964743-2963523 (Counterclockwise)

Preceding gene: 108757756

Following gene: 108762136

Centisome position: 32.44

GC content: 70.52

Gene sequence:

>1221_bases
GTGACTCACACCATGCGAGCCATCATCCATGTGGACATGGATGCCTTCTATGCATCCGTGGAGCAGCGGGACAACCCGGC
CCTGCGGGGCAAGCCGCTCATCGTGGGCGGGCATGCCCAGCGCGGTGTCGTGGTCGCCGCCTCCTACGAGGTGCGCCCGT
TCGGCGTGCGCAGCGCCATGCCCATGGCCCGTGCGACGAAGGCCGCGCCCCATGCGCTCGTCGTGAAGCCCCGCTTCGCC
GCCTATGCCGAGGCCAGTGAGCAGGTGTTCGCCATCTTCGAACGCTACACGCCGCTCATCGAGCCGCTGTCGCTCGACGA
GGCCTTCCTGGACGTGACGGCGTCGGTGGGCCTCTTCGGCACGCCCGCGGACATCGCCCGGCGCATCCGCAAGGAGATTG
CCGACGAGTTGAACCTCCCCGCCTCCGCGGGCGTGGCCACGGCGAAGTTCGTGGCGAAGATTGCCTCCGACCTCGCCAAG
CCCAATGGCCAGCGGGAGGTGCGCGCCGAGGAGACGGTGGCCTTCCTCGCGGGCCTGCCGGTGTCGCGCCTGTGGGGCGT
GGGGCCGAAGACGGAGGAGGCGCTCCGGCTCGCCGGGTTGAAGACGATTGGCGACGTGGCGTCCCGGGATTTGGAGTGGC
TGGAAGACAGGCTGGGCTCCAGCGGACGGCACCTGTGGGAGCTGTCCCAGGGCATCGACACGCGCGAGGTGGTGCCGGAC
CGGGCCGCCAAGAGCGTGGGCGCGGAGGACACCTTCGACGAAGACCTCGTGGGGGTGGACGCGCTCAAGCCGCACGTCCA
CGCCCAGGCCCTGCGCGTGGCCCGGCGGCTGCGGCGGGCGGCGCTGAAGGGCCGCGTGGTGCAGCTCAAATTGAAGTTCG
CGGACTTCACACTCATCACCCGTCGAACCACGCTGCGCGAGGCCACGGATGACGGGCAGACGCTCTACCGCGCGGCGCTG
GAGCTGCTGGACAAGTCGCACCAGGGCAAGCCGCTGCGGCTCACCGGCGTCAGCGTGCAGTTGGACGAGGAGCCGCCCCA
GTTGGGCCTCTTCCCCGCCGCCGCGCCGCGCACCGCGAAGCTGAACGCGGCGCTGGACAAGATTGCCGAGCGGTTTGGCA
GCAAGGCCATCACCACCGCGGACATCGCCGGCAGCGAGGCCACCGACAGCGCCGAACACCGCTCCGAGCGCCCGGTGGAC
AAGGGCGGGCCCAAGGACTGA

Upstream 100 bases:

>100_bases
TGAGACGGACCAACTCCCGCCGCCGAGGTGTCTCGAACCACAGGTACTCCGTCAGGCTCTTCATATCCGTATCCGCCAGG
CGTCAGAGTGCCCCGTTAAA

Downstream 100 bases:

>100_bases
GGGCCCCGGTAAGGGTGGGGCCTCACGCCCGTTCGCGGAGCGGCCCCACACCTCACGGAAGGGACTTCGACTCAGGCAGC
GCCCGCCCCGGAAGACGAGC

Product: putative DNA polymerase IV

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 406; Mature: 405

Protein sequence:

>406_residues
MTHTMRAIIHVDMDAFYASVEQRDNPALRGKPLIVGGHAQRGVVVAASYEVRPFGVRSAMPMARATKAAPHALVVKPRFA
AYAEASEQVFAIFERYTPLIEPLSLDEAFLDVTASVGLFGTPADIARRIRKEIADELNLPASAGVATAKFVAKIASDLAK
PNGQREVRAEETVAFLAGLPVSRLWGVGPKTEEALRLAGLKTIGDVASRDLEWLEDRLGSSGRHLWELSQGIDTREVVPD
RAAKSVGAEDTFDEDLVGVDALKPHVHAQALRVARRLRRAALKGRVVQLKLKFADFTLITRRTTLREATDDGQTLYRAAL
ELLDKSHQGKPLRLTGVSVQLDEEPPQLGLFPAAAPRTAKLNAALDKIAERFGSKAITTADIAGSEATDSAEHRSERPVD
KGGPKD

Sequences:

>Translated_406_residues
MTHTMRAIIHVDMDAFYASVEQRDNPALRGKPLIVGGHAQRGVVVAASYEVRPFGVRSAMPMARATKAAPHALVVKPRFA
AYAEASEQVFAIFERYTPLIEPLSLDEAFLDVTASVGLFGTPADIARRIRKEIADELNLPASAGVATAKFVAKIASDLAK
PNGQREVRAEETVAFLAGLPVSRLWGVGPKTEEALRLAGLKTIGDVASRDLEWLEDRLGSSGRHLWELSQGIDTREVVPD
RAAKSVGAEDTFDEDLVGVDALKPHVHAQALRVARRLRRAALKGRVVQLKLKFADFTLITRRTTLREATDDGQTLYRAAL
ELLDKSHQGKPLRLTGVSVQLDEEPPQLGLFPAAAPRTAKLNAALDKIAERFGSKAITTADIAGSEATDSAEHRSERPVD
KGGPKD
>Mature_405_residues
THTMRAIIHVDMDAFYASVEQRDNPALRGKPLIVGGHAQRGVVVAASYEVRPFGVRSAMPMARATKAAPHALVVKPRFAA
YAEASEQVFAIFERYTPLIEPLSLDEAFLDVTASVGLFGTPADIARRIRKEIADELNLPASAGVATAKFVAKIASDLAKP
NGQREVRAEETVAFLAGLPVSRLWGVGPKTEEALRLAGLKTIGDVASRDLEWLEDRLGSSGRHLWELSQGIDTREVVPDR
AAKSVGAEDTFDEDLVGVDALKPHVHAQALRVARRLRRAALKGRVVQLKLKFADFTLITRRTTLREATDDGQTLYRAALE
LLDKSHQGKPLRLTGVSVQLDEEPPQLGLFPAAAPRTAKLNAALDKIAERFGSKAITTADIAGSEATDSAEHRSERPVDK
GGPKD

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=428, Percent_Identity=26.6355140186916, Blast_Score=139, Evalue=6e-33,
Organism=Homo sapiens, GI7706681, Length=429, Percent_Identity=26.5734265734266, Blast_Score=138, Evalue=9e-33,
Organism=Homo sapiens, GI154350220, Length=358, Percent_Identity=27.6536312849162, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI5729982, Length=355, Percent_Identity=26.1971830985915, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI7705344, Length=108, Percent_Identity=43.5185185185185, Blast_Score=101, Evalue=2e-21,
Organism=Escherichia coli, GI1786425, Length=347, Percent_Identity=45.821325648415, Blast_Score=262, Evalue=3e-71,
Organism=Escherichia coli, GI1787432, Length=386, Percent_Identity=26.6839378238342, Blast_Score=107, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI115534089, Length=123, Percent_Identity=42.2764227642276, Blast_Score=98, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17537959, Length=220, Percent_Identity=27.2727272727273, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI193205700, Length=111, Percent_Identity=40.5405405405405, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI193205702, Length=271, Percent_Identity=28.0442804428044, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI19923006, Length=402, Percent_Identity=26.6169154228856, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI21355641, Length=283, Percent_Identity=31.8021201413428, Blast_Score=129, Evalue=5e-30,
Organism=Drosophila melanogaster, GI24644984, Length=283, Percent_Identity=31.8021201413428, Blast_Score=129, Evalue=5e-30,
Organism=Drosophila melanogaster, GI24668444, Length=470, Percent_Identity=24.468085106383, Blast_Score=104, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 44006; Mature: 43874

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHTMRAIIHVDMDAFYASVEQRDNPALRGKPLIVGGHAQRGVVVAASYEVRPFGVRSAM
CCCCEEEEEEECHHHHHHHHHHCCCCCCCCCCEEEECCCCCCEEEEEECEECCCCCHHCC
PMARATKAAPHALVVKPRFAAYAEASEQVFAIFERYTPLIEPLSLDEAFLDVTASVGLFG
CHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCC
TPADIARRIRKEIADELNLPASAGVATAKFVAKIASDLAKPNGQREVRAEETVAFLAGLP
CHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCC
VSRLWGVGPKTEEALRLAGLKTIGDVASRDLEWLEDRLGSSGRHLWELSQGIDTREVVPD
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCHHHHCCC
RAAKSVGAEDTFDEDLVGVDALKPHVHAQALRVARRLRRAALKGRVVQLKLKFADFTLIT
HHHHHCCCCCCCCHHHHCHHHHCHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECEEEEE
RRTTLREATDDGQTLYRAALELLDKSHQGKPLRLTGVSVQLDEEPPQLGLFPAAAPRTAK
HHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCHH
LNAALDKIAERFGSKAITTADIAGSEATDSAEHRSERPVDKGGPKD
HHHHHHHHHHHHCCCCEEEHHCCCCCCCCCHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
THTMRAIIHVDMDAFYASVEQRDNPALRGKPLIVGGHAQRGVVVAASYEVRPFGVRSAM
CCCEEEEEEECHHHHHHHHHHCCCCCCCCCCEEEECCCCCCEEEEEECEECCCCCHHCC
PMARATKAAPHALVVKPRFAAYAEASEQVFAIFERYTPLIEPLSLDEAFLDVTASVGLFG
CHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCC
TPADIARRIRKEIADELNLPASAGVATAKFVAKIASDLAKPNGQREVRAEETVAFLAGLP
CHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCC
VSRLWGVGPKTEEALRLAGLKTIGDVASRDLEWLEDRLGSSGRHLWELSQGIDTREVVPD
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCHHHHCCC
RAAKSVGAEDTFDEDLVGVDALKPHVHAQALRVARRLRRAALKGRVVQLKLKFADFTLIT
HHHHHCCCCCCCCHHHHCHHHHCHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECEEEEE
RRTTLREATDDGQTLYRAALELLDKSHQGKPLRLTGVSVQLDEEPPQLGLFPAAAPRTAK
HHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCHH
LNAALDKIAERFGSKAITTADIAGSEATDSAEHRSERPVDKGGPKD
HHHHHHHHHHHHCCCCEEEHHCCCCCCCCCHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA