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The map label for this gene is macB [H]

Identifier: 108763121

GI number: 108763121

Start: 4489837

End: 4492257

Strand: Direct

Name: macB [H]

Synonym: MXAN_3773

Alternate gene names: 108763121

Gene position: 4489837-4492257 (Clockwise)

Preceding gene: 108760417

Following gene: 108763670

Centisome position: 49.12

GC content: 71.95

Gene sequence:

>2421_bases
ATGACCTTCTTCGATTCGCTCGCCGCGGATGTTCGCTTCGCGCTCCGCACCTTCCGCCGCTCACCCGGCTTCGTCGCCGC
CGCCGTGATGTGCCTGGCGCTGGGTATTGGCGCCAACGCCGTCATCTTCAGCGTGGTTCACGGGGTCCTCCTCCGGCCGC
TGCCGTACGCGGAACCCGAGCGGCTGGTTAGTCTCGTCGAGGTGCGCCCCCAGGGCTATGGCGGCCCGGTGTCCTGGCCC
ACGTTCTGGGCCTGGCGCCAACACAGCCCGGCCTTCGAACAGATGGCGGCATTCACAGGCGGCGGCGTCACCCTCCAGGC
CCAGGATGCGCCTGAACGCCTCCAGGCTCTTCGCGGGACGGCTGACTTCTTCACGGTTCATGGCGTGCCGCCCTTGCTGG
GCCGGACTTTCGCGCTCGACGAGGACCTGCCCGGCCAGGCCCCGGTCGCGGTCCTCAGCGAGCGCCTCTGGCGCGCCCGT
TTTGGCGCCGACCCAGCCGTCCTCGGCCGTTCCGTGAGCCTGGATGGCCTGGCCCACACCGTCATTGGCGTGATGCCCGC
GTCTTTCGATGCGTCCACCGACGTGTGGCTGCCCCTGGTGGCTCCGCCGGACGCCGCCGCTCGGACCCGGTCCACGGTGC
TGACCCTCCGGGCCCGGCTGGCGCCAGGCGTTTCGCTGGCCTCCGCCGAGGCCCAGTTGAAGCAAGTCGCCGCGAACTCC
GCGGCGGCCCAGGCGGAATCCCACCGGGACCGGAGCGCCCGGGTCATTCCGCTCGATGAAAGCCAGACGCAGTCCTGGCG
GGCGCCGCTCCAGGTCCTGCTGGGCGCCGTCGCCCTGGTGCTCCTCATCGCGTGTACGAACGTCGCGAATCTGCTGCTGG
CCCGCGCGGGCACCCGGCGGCGCGAGCTGGCCGTTCGTCTGGCCCTGGGCGCCAGCCGGGCCCGGGTCGTCCAGCAGCTC
CTGGTCGAAAGCCTCCTGCTGGCGTTCCTGGGCGGCGTGCTGGCGGCCTTGCTGGCGCGTTGGGGCCTGGACGCGCTGCT
CGCCCTGGCGCCGGAGAGCCTGCCCCGGCGCCAGGACATCGTGTTGGACGGAACGGCCTTCCTGTTCCTCCTCGCAATCA
CCAGCGTCAGCGGCCTGGCCTTCGGGCTGCTTCCGGCCCTCCAGGTCTCCCGGCTGGACGTCCGTGGTGGGCTCGCCGCC
GCGGGCGATGGCAGCACGGTGCCGGGTTTCGGCCGTCGCCTGGGGGCCTCGCTGGTGGTTGTGGAGATCGCCCTATCGCT
GGTGCTGCTCGTCGGCGCGGGCCTGCTCGGACGCGGCTTTCTGCACCTGCTGGGGACTTCCACCGGACTTGCCCCTGGCC
AGGTCCTCACGCTGCACCTGTCCATCCCAGACGACCGGTTCTTCAAGGATGGCGCCCTGGACGCGGAGCTGCCGGGACGG
CTCTTGGAGCCGGTGCTGGAGGCGGTTCGCGCGCTCCCGGGCGTCACCGCGGCGGGCATGACGTCCGTGCTCCCCATCCA
ACGGGCCTGGAACAACGCTCGGTATCAGCTCGAAGGAGCGCCTCTGCCAGAGCCCGGCGACGAACCTCGCGCCGAGCGCC
GCGCCTCCAGTCCGGGCTACTTCGCCGCCATGGGCATCCCCCTTCGCCAGGGGCGCGATTTCACGTCCCTGGACGCCGCG
CCGGACCAGCCCGGCGTCGTCATCGTCAATGAAACCCTGGCCCGCCGGCACTTTCCGGCAGGAGGTGCCCTGGGCCACCA
GCTGCGCATCGGGGCGACGCCGTACACCATCGTCGGCGTCGTGGGCGATGTCCGCCAGGCGGGACTGGAGCGCGAACCGC
TCGCCGAGTTCCACGTCCCCCATGGCAGGCCCTGGGGCGATGACGGGCTCGTCCTGGTCACGCGCACCTCGGTGCAGCCG
GAGACGCTGCTGCCGGCCATCCAGGAGGCCATCCGCCGCGTGGATGGCACCGTGCCCGTCTACCGGGCGCTCACCCTGGA
ACAGGTCATCTCGCAATCCCTGGCGATGCGCAGACTCGTCCTGGGGCTGCTCGGCGGTTTTGCGGTCCTCGCCGTCCTGC
TCGCCGCCTACGGCCTCTACGGGGTCATCTCGCTCCGGGTCGTCCAGCGCACGCGGGAGCTGGGCGTCCGGATGGCGCTC
GGTGCCCGGCCCGCGGACGTGCTCCGGCTCGTCCTGGGCCAGGGCGCGGGCATGACAGCCGTGGGCCTCGGGGTGGGACT
TGGGGCCGCGTGGGCCCTGTCCCAGGTACTCGCAAGCCAGCTTCACGGCGTCAGCGCGCGGGATCCGTGGACGTTCGGGG
CCGTGGCGGCGCTGCTGGCGGCCGTGGCGTTGCTCGCCTGTTGGATTCCGGCCCGGCGGGCGATACGGATGGACCCGCTT
CAGGCGCTCCGGAAGGAATGA

Upstream 100 bases:

>100_bases
TTCAGGCCGTTCCCCGCCCTGGTTTCTGGGCCGTCCGGGCCGGTTTCGGGTCCGTCGATTGCAGTCGAATCCGGCAAGAT
CTCCACTCCCGACGCCCGCC

Downstream 100 bases:

>100_bases
CGTCGGGACTTCCGCGTCCCATGCGCGGGATGCGGAATCCCAGTCATGGAACGCCGCCGGATGACACGTCGCGTTGACGG
GAAATCCAGACGCGAATGCG

Product: putative permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 806; Mature: 805

Protein sequence:

>806_residues
MTFFDSLAADVRFALRTFRRSPGFVAAAVMCLALGIGANAVIFSVVHGVLLRPLPYAEPERLVSLVEVRPQGYGGPVSWP
TFWAWRQHSPAFEQMAAFTGGGVTLQAQDAPERLQALRGTADFFTVHGVPPLLGRTFALDEDLPGQAPVAVLSERLWRAR
FGADPAVLGRSVSLDGLAHTVIGVMPASFDASTDVWLPLVAPPDAAARTRSTVLTLRARLAPGVSLASAEAQLKQVAANS
AAAQAESHRDRSARVIPLDESQTQSWRAPLQVLLGAVALVLLIACTNVANLLLARAGTRRRELAVRLALGASRARVVQQL
LVESLLLAFLGGVLAALLARWGLDALLALAPESLPRRQDIVLDGTAFLFLLAITSVSGLAFGLLPALQVSRLDVRGGLAA
AGDGSTVPGFGRRLGASLVVVEIALSLVLLVGAGLLGRGFLHLLGTSTGLAPGQVLTLHLSIPDDRFFKDGALDAELPGR
LLEPVLEAVRALPGVTAAGMTSVLPIQRAWNNARYQLEGAPLPEPGDEPRAERRASSPGYFAAMGIPLRQGRDFTSLDAA
PDQPGVVIVNETLARRHFPAGGALGHQLRIGATPYTIVGVVGDVRQAGLEREPLAEFHVPHGRPWGDDGLVLVTRTSVQP
ETLLPAIQEAIRRVDGTVPVYRALTLEQVISQSLAMRRLVLGLLGGFAVLAVLLAAYGLYGVISLRVVQRTRELGVRMAL
GARPADVLRLVLGQGAGMTAVGLGVGLGAAWALSQVLASQLHGVSARDPWTFGAVAALLAAVALLACWIPARRAIRMDPL
QALRKE

Sequences:

>Translated_806_residues
MTFFDSLAADVRFALRTFRRSPGFVAAAVMCLALGIGANAVIFSVVHGVLLRPLPYAEPERLVSLVEVRPQGYGGPVSWP
TFWAWRQHSPAFEQMAAFTGGGVTLQAQDAPERLQALRGTADFFTVHGVPPLLGRTFALDEDLPGQAPVAVLSERLWRAR
FGADPAVLGRSVSLDGLAHTVIGVMPASFDASTDVWLPLVAPPDAAARTRSTVLTLRARLAPGVSLASAEAQLKQVAANS
AAAQAESHRDRSARVIPLDESQTQSWRAPLQVLLGAVALVLLIACTNVANLLLARAGTRRRELAVRLALGASRARVVQQL
LVESLLLAFLGGVLAALLARWGLDALLALAPESLPRRQDIVLDGTAFLFLLAITSVSGLAFGLLPALQVSRLDVRGGLAA
AGDGSTVPGFGRRLGASLVVVEIALSLVLLVGAGLLGRGFLHLLGTSTGLAPGQVLTLHLSIPDDRFFKDGALDAELPGR
LLEPVLEAVRALPGVTAAGMTSVLPIQRAWNNARYQLEGAPLPEPGDEPRAERRASSPGYFAAMGIPLRQGRDFTSLDAA
PDQPGVVIVNETLARRHFPAGGALGHQLRIGATPYTIVGVVGDVRQAGLEREPLAEFHVPHGRPWGDDGLVLVTRTSVQP
ETLLPAIQEAIRRVDGTVPVYRALTLEQVISQSLAMRRLVLGLLGGFAVLAVLLAAYGLYGVISLRVVQRTRELGVRMAL
GARPADVLRLVLGQGAGMTAVGLGVGLGAAWALSQVLASQLHGVSARDPWTFGAVAALLAAVALLACWIPARRAIRMDPL
QALRKE
>Mature_805_residues
TFFDSLAADVRFALRTFRRSPGFVAAAVMCLALGIGANAVIFSVVHGVLLRPLPYAEPERLVSLVEVRPQGYGGPVSWPT
FWAWRQHSPAFEQMAAFTGGGVTLQAQDAPERLQALRGTADFFTVHGVPPLLGRTFALDEDLPGQAPVAVLSERLWRARF
GADPAVLGRSVSLDGLAHTVIGVMPASFDASTDVWLPLVAPPDAAARTRSTVLTLRARLAPGVSLASAEAQLKQVAANSA
AAQAESHRDRSARVIPLDESQTQSWRAPLQVLLGAVALVLLIACTNVANLLLARAGTRRRELAVRLALGASRARVVQQLL
VESLLLAFLGGVLAALLARWGLDALLALAPESLPRRQDIVLDGTAFLFLLAITSVSGLAFGLLPALQVSRLDVRGGLAAA
GDGSTVPGFGRRLGASLVVVEIALSLVLLVGAGLLGRGFLHLLGTSTGLAPGQVLTLHLSIPDDRFFKDGALDAELPGRL
LEPVLEAVRALPGVTAAGMTSVLPIQRAWNNARYQLEGAPLPEPGDEPRAERRASSPGYFAAMGIPLRQGRDFTSLDAAP
DQPGVVIVNETLARRHFPAGGALGHQLRIGATPYTIVGVVGDVRQAGLEREPLAEFHVPHGRPWGDDGLVLVTRTSVQPE
TLLPAIQEAIRRVDGTVPVYRALTLEQVISQSLAMRRLVLGLLGGFAVLAVLLAAYGLYGVISLRVVQRTRELGVRMALG
ARPADVLRLVLGQGAGMTAVGLGVGLGAAWALSQVLASQLHGVSARDPWTFGAVAALLAAVALLACWIPARRAIRMDPLQ
ALRKE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=280, Percent_Identity=28.5714285714286, Blast_Score=85, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 85068; Mature: 84937

Theoretical pI: Translated: 10.44; Mature: 10.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFFDSLAADVRFALRTFRRSPGFVAAAVMCLALGIGANAVIFSVVHGVLLRPLPYAEPE
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHH
RLVSLVEVRPQGYGGPVSWPTFWAWRQHSPAFEQMAAFTGGGVTLQAQDAPERLQALRGT
HHHHHHHHCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHCC
ADFFTVHGVPPLLGRTFALDEDLPGQAPVAVLSERLWRARFGADPAVLGRSVSLDGLAHT
CCEEEECCCCHHHCCEEECCCCCCCCCHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHH
VIGVMPASFDASTDVWLPLVAPPDAAARTRSTVLTLRARLAPGVSLASAEAQLKQVAANS
HHHHCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
AAAQAESHRDRSARVIPLDESQTQSWRAPLQVLLGAVALVLLIACTNVANLLLARAGTRR
HHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
RELAVRLALGASRARVVQQLLVESLLLAFLGGVLAALLARWGLDALLALAPESLPRRQDI
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCCCCE
VLDGTAFLFLLAITSVSGLAFGLLPALQVSRLDVRGGLAAAGDGSTVPGFGRRLGASLVV
EECHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEECCCCCCCCCHHHHHHHHHHH
VEIALSLVLLVGAGLLGRGFLHLLGTSTGLAPGQVLTLHLSIPDDRFFKDGALDAELPGR
HHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCHH
LLEPVLEAVRALPGVTAAGMTSVLPIQRAWNNARYQLEGAPLPEPGDEPRAERRASSPGY
HHHHHHHHHHHCCCCCHHCHHHHHHHHHHCCCCCEEECCCCCCCCCCCCHHHHCCCCCCE
FAAMGIPLRQGRDFTSLDAAPDQPGVVIVNETLARRHFPAGGALGHQLRIGATPYTIVGV
EEEECCCHHCCCCCCCCCCCCCCCCEEEEECHHHHHCCCCCCCCCCEEEECCCCEEEHHH
VGDVRQAGLEREPLAEFHVPHGRPWGDDGLVLVTRTSVQPETLLPAIQEAIRRVDGTVPV
HHHHHHCCCCCCCHHHHCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCHH
YRALTLEQVISQSLAMRRLVLGLLGGFAVLAVLLAAYGLYGVISLRVVQRTRELGVRMAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCC
GARPADVLRLVLGQGAGMTAVGLGVGLGAAWALSQVLASQLHGVSARDPWTFGAVAALLA
CCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
AVALLACWIPARRAIRMDPLQALRKE
HHHHHHHHHHHHHHHCCCHHHHHHCC
>Mature Secondary Structure 
TFFDSLAADVRFALRTFRRSPGFVAAAVMCLALGIGANAVIFSVVHGVLLRPLPYAEPE
CCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHH
RLVSLVEVRPQGYGGPVSWPTFWAWRQHSPAFEQMAAFTGGGVTLQAQDAPERLQALRGT
HHHHHHHHCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHCC
ADFFTVHGVPPLLGRTFALDEDLPGQAPVAVLSERLWRARFGADPAVLGRSVSLDGLAHT
CCEEEECCCCHHHCCEEECCCCCCCCCHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHH
VIGVMPASFDASTDVWLPLVAPPDAAARTRSTVLTLRARLAPGVSLASAEAQLKQVAANS
HHHHCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
AAAQAESHRDRSARVIPLDESQTQSWRAPLQVLLGAVALVLLIACTNVANLLLARAGTRR
HHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
RELAVRLALGASRARVVQQLLVESLLLAFLGGVLAALLARWGLDALLALAPESLPRRQDI
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCCCCE
VLDGTAFLFLLAITSVSGLAFGLLPALQVSRLDVRGGLAAAGDGSTVPGFGRRLGASLVV
EECHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEECCCCCCCCCHHHHHHHHHHH
VEIALSLVLLVGAGLLGRGFLHLLGTSTGLAPGQVLTLHLSIPDDRFFKDGALDAELPGR
HHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCHH
LLEPVLEAVRALPGVTAAGMTSVLPIQRAWNNARYQLEGAPLPEPGDEPRAERRASSPGY
HHHHHHHHHHHCCCCCHHCHHHHHHHHHHCCCCCEEECCCCCCCCCCCCHHHHCCCCCCE
FAAMGIPLRQGRDFTSLDAAPDQPGVVIVNETLARRHFPAGGALGHQLRIGATPYTIVGV
EEEECCCHHCCCCCCCCCCCCCCCCEEEEECHHHHHCCCCCCCCCCEEEECCCCEEEHHH
VGDVRQAGLEREPLAEFHVPHGRPWGDDGLVLVTRTSVQPETLLPAIQEAIRRVDGTVPV
HHHHHHCCCCCCCHHHHCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCHH
YRALTLEQVISQSLAMRRLVLGLLGGFAVLAVLLAAYGLYGVISLRVVQRTRELGVRMAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCC
GARPADVLRLVLGQGAGMTAVGLGVGLGAAWALSQVLASQLHGVSARDPWTFGAVAALLA
CCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
AVALLACWIPARRAIRMDPLQALRKE
HHHHHHHHHHHHHHHCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA