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The map label for this gene is tig [H]

Identifier: 108763072

GI number: 108763072

Start: 1370885

End: 1372117

Strand: Direct

Name: tig [H]

Synonym: MXAN_1178

Alternate gene names: 108763072

Gene position: 1370885-1372117 (Clockwise)

Preceding gene: 108757997

Following gene: 108756968

Centisome position: 15.0

GC content: 68.61

Gene sequence:

>1233_bases
GTGCGGCCGTCTCCACCGTGTCCGGCTTCATCGGCTCCTTCTTCTAGGAAGCGCCGCGTCGTCAATCTCAACGCTCCGGG
GGGCTTCGGTCCTTCCGGAGCGTTGTGCTATCCGAGGGGGACGGAGCGAGAGACCATGACGACCCATGACGATTCGCAGG
GCGGTCGTAAGAATGCCCGTTCGCTGGCTGAGCTTCATGCGCTCGGCATCATGAAGAAGATGCCGGCGGCGCTGCAGCTC
GACAGCACCGAGCCGGTGGAGCTTCCCACGGTGGAGGCGCCTTCCCTGGAGGGGGTGTCGGTGGCCCAGGTGGCGCCTGC
GCCATTGACGGAGCAGGAACTCGTGGACCGCTTCGATGCGCTCCGTCGCCAGCACGCAGACGTCCGCGAGCGTCAGCCGG
GCGAGGATGTGGCGCTCGAGGACGACGCGCTCGTGGACGTGCTGGGCTTCGCCAACAACCGGCTGATGCCCTTCTCTGTC
CGGGAGAACTGGTGGGTGCGCGTCGCGGCGGACCCGGGGCTGCCCGGCTTCTTCGAATCACTGGCGGGGGCGAAGGTGGG
CCAGTCGGTCGGCATCGAGCTGACGCTGCCGGACACCTATCCCGTGGAGGCGCTGCGGGGGCAGCCGGCCCGCTTCCTCG
TGAGCGTGAAGGCGGCGCGAGAGCTGAAGTTGCTGGAAGATGACTCGCCGGAGTTGCTGTCACGGCTGGGCATGGGCTCC
ATCACGGACGTCATGCGCAAGCTGGGGGACGAACTGGCCCAGGCGCGGCTCGCCGACGTCGACCGGTTGACCCAGGAGCG
CGTCATGGACGTGCTCGTGGACCGCACGCCGGTGGAGCTGTCCGCCGCGCTGGTGGATGAGGAGATTCGCCAGCGCTGGG
CGGAGGCCGAGCGGCCCATCCTCCAGCGCAAGGATTTCCAGCCCGACGAGCTTCAGGAAGCGCTGGAGGGGTGGCTGCAG
GATCCGCTGACCCGCATGGATGCGGCGTACCGCATCACGCTGGCGCTGGTCCTGCGAGCCATCGCCGAACGCGACGGCAT
CCAGCCGGACCGCGCGGCGACGGAGGCCATGCTGGAGGACCTCGCGAACCTCACGGGCGTCAACCGGCAGGAGCTGGGCG
TGGCGGTGAAGGAGGACGAGGCGCTGGCTCGCCGCCTGTACGAAATGGCGCTGCGCTTCTCCACCATCGACCACGTGATG
AAGAAGGTGACGCTGACGCCCGCCGCGGCGTGA

Upstream 100 bases:

>100_bases
ACGGACCCGAACGCTTCGGCTGGAAAGAAGATTACCGCTGGAGTGACGGCGCTGGGGTCCATCGCCGCTGCCACCAACAT
CCCGGTCGTGAGCCAGGTGG

Downstream 100 bases:

>100_bases
GCCTCAGCGCGCTTCCAAGGCCAGGGCGACCATCACCTCGGTGAGGTCGCCCGGGTGGTAGCGGACCAGGCCTGGCAGGC
CGCGCAGCGCGGCCTCCGCG

Product: FKBP-type peptidyl-prolyl cis-trans isomerase

Products: peptidylproline (w =0) [C]

Alternate protein names: TF [H]

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MRPSPPCPASSAPSSRKRRVVNLNAPGGFGPSGALCYPRGTERETMTTHDDSQGGRKNARSLAELHALGIMKKMPAALQL
DSTEPVELPTVEAPSLEGVSVAQVAPAPLTEQELVDRFDALRRQHADVRERQPGEDVALEDDALVDVLGFANNRLMPFSV
RENWWVRVAADPGLPGFFESLAGAKVGQSVGIELTLPDTYPVEALRGQPARFLVSVKAARELKLLEDDSPELLSRLGMGS
ITDVMRKLGDELAQARLADVDRLTQERVMDVLVDRTPVELSAALVDEEIRQRWAEAERPILQRKDFQPDELQEALEGWLQ
DPLTRMDAAYRITLALVLRAIAERDGIQPDRAATEAMLEDLANLTGVNRQELGVAVKEDEALARRLYEMALRFSTIDHVM
KKVTLTPAAA

Sequences:

>Translated_410_residues
MRPSPPCPASSAPSSRKRRVVNLNAPGGFGPSGALCYPRGTERETMTTHDDSQGGRKNARSLAELHALGIMKKMPAALQL
DSTEPVELPTVEAPSLEGVSVAQVAPAPLTEQELVDRFDALRRQHADVRERQPGEDVALEDDALVDVLGFANNRLMPFSV
RENWWVRVAADPGLPGFFESLAGAKVGQSVGIELTLPDTYPVEALRGQPARFLVSVKAARELKLLEDDSPELLSRLGMGS
ITDVMRKLGDELAQARLADVDRLTQERVMDVLVDRTPVELSAALVDEEIRQRWAEAERPILQRKDFQPDELQEALEGWLQ
DPLTRMDAAYRITLALVLRAIAERDGIQPDRAATEAMLEDLANLTGVNRQELGVAVKEDEALARRLYEMALRFSTIDHVM
KKVTLTPAAA
>Mature_410_residues
MRPSPPCPASSAPSSRKRRVVNLNAPGGFGPSGALCYPRGTERETMTTHDDSQGGRKNARSLAELHALGIMKKMPAALQL
DSTEPVELPTVEAPSLEGVSVAQVAPAPLTEQELVDRFDALRRQHADVRERQPGEDVALEDDALVDVLGFANNRLMPFSV
RENWWVRVAADPGLPGFFESLAGAKVGQSVGIELTLPDTYPVEALRGQPARFLVSVKAARELKLLEDDSPELLSRLGMGS
ITDVMRKLGDELAQARLADVDRLTQERVMDVLVDRTPVELSAALVDEEIRQRWAEAERPILQRKDFQPDELQEALEGWLQ
DPLTRMDAAYRITLALVLRAIAERDGIQPDRAATEAMLEDLANLTGVNRQELGVAVKEDEALARRLYEMALRFSTIDHVM
KKVTLTPAAA

Specific function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation [H]

COG id: COG0544

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1786640, Length=300, Percent_Identity=24.3333333333333, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: 1070 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 500 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 340 Molecules/Cell In: Growth-Phase, Mini

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179
- InterPro:   IPR005215
- InterPro:   IPR008880
- InterPro:   IPR008881 [H]

Pfam domain/function: PF00254 FKBP_C; PF05698 Trigger_C; PF05697 Trigger_N [H]

EC number: NA

Molecular weight: Translated: 45101; Mature: 45101

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPSPPCPASSAPSSRKRRVVNLNAPGGFGPSGALCYPRGTERETMTTHDDSQGGRKNAR
CCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCHHHHH
SLAELHALGIMKKMPAALQLDSTEPVELPTVEAPSLEGVSVAQVAPAPLTEQELVDRFDA
HHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHH
LRRQHADVRERQPGEDVALEDDALVDVLGFANNRLMPFSVRENWWVRVAADPGLPGFFES
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCEEEEEECCCEEEEEEECCCCCHHHHH
LAGAKVGQSVGIELTLPDTYPVEALRGQPARFLVSVKAARELKLLEDDSPELLSRLGMGS
HHHHHCCCCCCEEEECCCCCCHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCH
ITDVMRKLGDELAQARLADVDRLTQERVMDVLVDRTPVELSAALVDEEIRQRWAEAERPI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCH
LQRKDFQPDELQEALEGWLQDPLTRMDAAYRITLALVLRAIAERDGIQPDRAATEAMLED
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
LANLTGVNRQELGVAVKEDEALARRLYEMALRFSTIDHVMKKVTLTPAAA
HHHHCCCCHHHHCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MRPSPPCPASSAPSSRKRRVVNLNAPGGFGPSGALCYPRGTERETMTTHDDSQGGRKNAR
CCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCHHHHH
SLAELHALGIMKKMPAALQLDSTEPVELPTVEAPSLEGVSVAQVAPAPLTEQELVDRFDA
HHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHH
LRRQHADVRERQPGEDVALEDDALVDVLGFANNRLMPFSVRENWWVRVAADPGLPGFFES
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCEEEEEECCCEEEEEEECCCCCHHHHH
LAGAKVGQSVGIELTLPDTYPVEALRGQPARFLVSVKAARELKLLEDDSPELLSRLGMGS
HHHHHCCCCCCEEEECCCCCCHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCH
ITDVMRKLGDELAQARLADVDRLTQERVMDVLVDRTPVELSAALVDEEIRQRWAEAERPI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCH
LQRKDFQPDELQEALEGWLQDPLTRMDAAYRITLALVLRAIAERDGIQPDRAATEAMLED
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
LANLTGVNRQELGVAVKEDEALARRLYEMALRFSTIDHVMKKVTLTPAAA
HHHHCCCCHHHHCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: peptidylproline (w =180) [C]

Specific reaction: peptidylproline (w =180) = peptidylproline (w =0) [C]

General reaction: Isomerases; cis-trans-Isomerases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]