Click here to switch to the map view.

The map label for this gene is phoP [H]

Identifier: 108763038

GI number: 108763038

Start: 6615375

End: 6616055

Strand: Direct

Name: phoP [H]

Synonym: MXAN_5313

Alternate gene names: 108763038

Gene position: 6615375-6616055 (Clockwise)

Preceding gene: 108756926

Following gene: 108763854

Centisome position: 72.38

GC content: 70.34

Gene sequence:

>681_bases
ATGTCCACGCGCGTCCTGCTCATCGACGACGACACCCGGATGTATGAACTGCTCGAGCAGTACCTCGGGCAGAACGGCCT
CAGCGTCACCCACGCGGCGGATGGCGGACGGGGGCTGGCGGCGCTGGAGGCCAGTGCCTTCGACGCGGTGCTGCTCGACG
TGATGATGCCCGGCATGGACGGCCTGGAGGTCTGCAAGCGCATCCGCGCCAAGAGCCGCATCCCCGTCATCATGCTCACC
GCGAAGGGCGACGAGACGGACCGCGTGGTGGGCTTGGAGCTGGGCGCGGACGACTACCTCCCCAAGCCCTTCAGTCCCCG
AGAGCTGCTGGCGCGGCTGCGGGCCGTACTCCGCCGCTCGCAGCCCTCGGCGGTGGCGGACCGGCTAGAGTCGGGCGGCG
TGTCCATCGACGTGGCCGGGCGCGAGGTACGCGTGGAGGAGCGCGCCGTGGAGTTGACGGGCCTGGAGTTCGATTTACTC
GTCGCGCTGGTGCGCAGGGCCGGACGCGTCGTTCCGCGCGACGCCCTGCTGGGCGAGGCGGGCCGCAGTGACACGGTGGT
GGGCGAGCGCACCGTCGACGTGCACATCTCCCACCTGCGACAGAAGCTCGGTGACGTGGGCACCCGCCTCATCAAGACGG
TGCGCGGCGTGGGCTACGTGTTCGCCAAGGAGGGTCCGTGA

Upstream 100 bases:

>100_bases
CCACGGCAGGTGGGAGCCTTCCAGCCAGCGAGGGGTGGCCCCCCCGCCGGCGACTCGCGTGTCCATCCACACGGCCTCCC
CCTGAAGTAGAAGGCGGTTC

Downstream 100 bases:

>100_bases
AACGCGGCAGGCCCCGGGCGCACAAGCGCGGCTGGGACGCGTGGGGCGAGCCGCGCGAATGCGGCCCCTGGGGACACCGG
CATCCGCCGCACGGTTACTG

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MSTRVLLIDDDTRMYELLEQYLGQNGLSVTHAADGGRGLAALEASAFDAVLLDVMMPGMDGLEVCKRIRAKSRIPVIMLT
AKGDETDRVVGLELGADDYLPKPFSPRELLARLRAVLRRSQPSAVADRLESGGVSIDVAGREVRVEERAVELTGLEFDLL
VALVRRAGRVVPRDALLGEAGRSDTVVGERTVDVHISHLRQKLGDVGTRLIKTVRGVGYVFAKEGP

Sequences:

>Translated_226_residues
MSTRVLLIDDDTRMYELLEQYLGQNGLSVTHAADGGRGLAALEASAFDAVLLDVMMPGMDGLEVCKRIRAKSRIPVIMLT
AKGDETDRVVGLELGADDYLPKPFSPRELLARLRAVLRRSQPSAVADRLESGGVSIDVAGREVRVEERAVELTGLEFDLL
VALVRRAGRVVPRDALLGEAGRSDTVVGERTVDVHISHLRQKLGDVGTRLIKTVRGVGYVFAKEGP
>Mature_225_residues
STRVLLIDDDTRMYELLEQYLGQNGLSVTHAADGGRGLAALEASAFDAVLLDVMMPGMDGLEVCKRIRAKSRIPVIMLTA
KGDETDRVVGLELGADDYLPKPFSPRELLARLRAVLRRSQPSAVADRLESGGVSIDVAGREVRVEERAVELTGLEFDLLV
ALVRRAGRVVPRDALLGEAGRSDTVVGERTVDVHISHLRQKLGDVGTRLIKTVRGVGYVFAKEGP

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=233, Percent_Identity=42.4892703862661, Blast_Score=179, Evalue=1e-46,
Organism=Escherichia coli, GI1786599, Length=226, Percent_Identity=41.5929203539823, Blast_Score=169, Evalue=1e-43,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=43.421052631579, Blast_Score=157, Evalue=7e-40,
Organism=Escherichia coli, GI1788394, Length=227, Percent_Identity=37.8854625550661, Blast_Score=154, Evalue=4e-39,
Organism=Escherichia coli, GI87082012, Length=219, Percent_Identity=40.1826484018265, Blast_Score=148, Evalue=2e-37,
Organism=Escherichia coli, GI1789402, Length=222, Percent_Identity=39.6396396396396, Blast_Score=140, Evalue=5e-35,
Organism=Escherichia coli, GI1786784, Length=220, Percent_Identity=34.0909090909091, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1786911, Length=222, Percent_Identity=36.036036036036, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1790860, Length=222, Percent_Identity=36.9369369369369, Blast_Score=127, Evalue=5e-31,
Organism=Escherichia coli, GI1790552, Length=219, Percent_Identity=36.0730593607306, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1787229, Length=231, Percent_Identity=31.1688311688312, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=31.2217194570136, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI145693140, Length=235, Percent_Identity=34.468085106383, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1790863, Length=231, Percent_Identity=27.2727272727273, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1790299, Length=137, Percent_Identity=35.036496350365, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1788550, Length=109, Percent_Identity=37.6146788990826, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1788191, Length=120, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790437, Length=118, Percent_Identity=35.5932203389831, Blast_Score=64, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=103, Percent_Identity=32.0388349514563, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 24542; Mature: 24411

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTRVLLIDDDTRMYELLEQYLGQNGLSVTHAADGGRGLAALEASAFDAVLLDVMMPGMD
CCCEEEEEECCHHHHHHHHHHHCCCCCEEEECCCCCCCEEHHHHHHHHHHHHHHHCCCCC
GLEVCKRIRAKSRIPVIMLTAKGDETDRVVGLELGADDYLPKPFSPRELLARLRAVLRRS
HHHHHHHHHHCCCCCEEEEEECCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCC
QPSAVADRLESGGVSIDVAGREVRVEERAVELTGLEFDLLVALVRRAGRVVPRDALLGEA
CCHHHHHHHHHCCEEEEECCCEEEHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHCCC
GRSDTVVGERTVDVHISHLRQKLGDVGTRLIKTVRGVGYVFAKEGP
CCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCC
>Mature Secondary Structure 
STRVLLIDDDTRMYELLEQYLGQNGLSVTHAADGGRGLAALEASAFDAVLLDVMMPGMD
CCEEEEEECCHHHHHHHHHHHCCCCCEEEECCCCCCCEEHHHHHHHHHHHHHHHCCCCC
GLEVCKRIRAKSRIPVIMLTAKGDETDRVVGLELGADDYLPKPFSPRELLARLRAVLRRS
HHHHHHHHHHCCCCCEEEEEECCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCC
QPSAVADRLESGGVSIDVAGREVRVEERAVELTGLEFDLLVALVRRAGRVVPRDALLGEA
CCHHHHHHHHHCCEEEEECCCEEEHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHCCC
GRSDTVVGERTVDVHISHLRQKLGDVGTRLIKTVRGVGYVFAKEGP
CCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]