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The map label for this gene is qorA [H]

Identifier: 108762995

GI number: 108762995

Start: 961039

End: 962025

Strand: Reverse

Name: qorA [H]

Synonym: MXAN_0845

Alternate gene names: 108762995

Gene position: 962025-961039 (Counterclockwise)

Preceding gene: 108756782

Following gene: 108761030

Centisome position: 10.53

GC content: 68.9

Gene sequence:

>987_bases
ATGAAAGCAGTGCGGTTCTCAGCCTTCGGACAGCCACTGAAGGTGGTGGAAGTCGTGGAGCAGCCGGACGTGGCGCTGAA
GCCGGGCGAGGCCCGGGTTGAAGTGCTGGCCACGCCCATCAATCCCTCCGACATCCTCACGCTCAGCGGCCAGTACGGGC
AGCTCCCGAAGCTCCCCGCTGTGCCCGGCAACGAAGGCGTCGGCCGCGTCGTCGAGGTCCAGGACTCCAGCGCCGTGAAG
GTGGGTGACATCGTATTCCTCCCGCTGGGCGCGGGCACCTGGTGCACCCACTTGGTCGCTCCCGCGGACTCGCTCCTGCG
GGTGCCGCCGGGAACCGACCTGCGGCAGGCCGCCATGCTGTTCATCAATCCTCCGACCGCGGACCTCCTGCTGCGGGACT
TCATCGCGCTGCAGCCCGGCGAGTGGGTGATACAGAACGCCGCCAACTCGGCGGTGGGCCGCTCCATCATCACCCTGGCG
AAGCAGGCTGGCTTCAAGACGCTGAACGTGGTGCGGCGTGAAGAGCTGGCGCCGGAGCTCACCGCGCTGGGCGCGGACGC
CGTGCTGCTGGACTCGGATGAACTGCCGGAGCGCGTGCGCGAAGTGACGGGCGGCGCCAAGGTCCGGCTGGCCATCGACG
CCGTCGGCGGTGAATCCACCCAACGCCTGGGTGACGCGCTCGCGCGCGGCGGCGTGGTGGTGAACTATGGCGCGATGAGC
GGAAAGGGCCCTCGGTTGTCAGCCGCCGCCACCATCTTCAAGGACATCACCCTGCGCGGCTTCTGGCTGGTGACGTGGAC
GAAGAAGACACCGCGCGAGGAGCAGGGCGCCCTGTTCGCCCGGCTCGCGAAGCAGGTGGCGGAAGGCGCACTGCACGTCC
CGGTAGAGGGAACCTTCCCCTTGGAGTCCATCCAGGAGGCCCTGACGCGCGCCATGGAAGGTGGGCGCGCCGGCAAGGTG
CTCCTCACGCCCAACGGCCCACTCTGA

Upstream 100 bases:

>100_bases
GGCAAAGCGGTGGGGCACGGCGACTGCTTGGATGCTCGGCGCGCCCCTCGAAGGCCGCTAGGGTGCGCCCCACACTCCCA
CACGAAGCATGGAGCGTCCC

Downstream 100 bases:

>100_bases
GGCGCTGAGCGCCGCCGCTCCGTCAGCCCCATGGCCCCTGGAACAACACCCCGAAGCGCAGGGCCAGCTCCGGACGCCGC
ACCAGCAGCGTCCCCCACGC

Product: zinc-binding dehydrogenase family oxidoreductase

Products: NA

Alternate protein names: NADPH:quinone reductase 1; Zeta-crystallin homolog protein [H]

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MKAVRFSAFGQPLKVVEVVEQPDVALKPGEARVEVLATPINPSDILTLSGQYGQLPKLPAVPGNEGVGRVVEVQDSSAVK
VGDIVFLPLGAGTWCTHLVAPADSLLRVPPGTDLRQAAMLFINPPTADLLLRDFIALQPGEWVIQNAANSAVGRSIITLA
KQAGFKTLNVVRREELAPELTALGADAVLLDSDELPERVREVTGGAKVRLAIDAVGGESTQRLGDALARGGVVVNYGAMS
GKGPRLSAAATIFKDITLRGFWLVTWTKKTPREEQGALFARLAKQVAEGALHVPVEGTFPLESIQEALTRAMEGGRAGKV
LLTPNGPL

Sequences:

>Translated_328_residues
MKAVRFSAFGQPLKVVEVVEQPDVALKPGEARVEVLATPINPSDILTLSGQYGQLPKLPAVPGNEGVGRVVEVQDSSAVK
VGDIVFLPLGAGTWCTHLVAPADSLLRVPPGTDLRQAAMLFINPPTADLLLRDFIALQPGEWVIQNAANSAVGRSIITLA
KQAGFKTLNVVRREELAPELTALGADAVLLDSDELPERVREVTGGAKVRLAIDAVGGESTQRLGDALARGGVVVNYGAMS
GKGPRLSAAATIFKDITLRGFWLVTWTKKTPREEQGALFARLAKQVAEGALHVPVEGTFPLESIQEALTRAMEGGRAGKV
LLTPNGPL
>Mature_328_residues
MKAVRFSAFGQPLKVVEVVEQPDVALKPGEARVEVLATPINPSDILTLSGQYGQLPKLPAVPGNEGVGRVVEVQDSSAVK
VGDIVFLPLGAGTWCTHLVAPADSLLRVPPGTDLRQAAMLFINPPTADLLLRDFIALQPGEWVIQNAANSAVGRSIITLA
KQAGFKTLNVVRREELAPELTALGADAVLLDSDELPERVREVTGGAKVRLAIDAVGGESTQRLGDALARGGVVVNYGAMS
GKGPRLSAAATIFKDITLRGFWLVTWTKKTPREEQGALFARLAKQVAEGALHVPVEGTFPLESIQEALTRAMEGGRAGKV
LLTPNGPL

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI67078404, Length=330, Percent_Identity=40.3030303030303, Blast_Score=214, Evalue=1e-55,
Organism=Homo sapiens, GI67078406, Length=296, Percent_Identity=41.554054054054, Blast_Score=199, Evalue=4e-51,
Organism=Homo sapiens, GI18379349, Length=310, Percent_Identity=26.7741935483871, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI194239674, Length=332, Percent_Identity=27.1084337349398, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI13236495, Length=332, Percent_Identity=27.1084337349398, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI22538446, Length=343, Percent_Identity=27.9883381924198, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI22538444, Length=343, Percent_Identity=27.9883381924198, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI194239676, Length=330, Percent_Identity=28.1818181818182, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI24308257, Length=348, Percent_Identity=22.7011494252874, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1790485, Length=332, Percent_Identity=29.2168674698795, Blast_Score=89, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17556000, Length=336, Percent_Identity=36.6071428571429, Blast_Score=186, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17536829, Length=288, Percent_Identity=39.5833333333333, Blast_Score=177, Evalue=7e-45,
Organism=Caenorhabditis elegans, GI17507255, Length=195, Percent_Identity=29.7435897435897, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6319500, Length=269, Percent_Identity=33.8289962825279, Blast_Score=123, Evalue=4e-29,
Organism=Drosophila melanogaster, GI45550423, Length=312, Percent_Identity=36.5384615384615, Blast_Score=188, Evalue=4e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 34649; Mature: 34649

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAVRFSAFGQPLKVVEVVEQPDVALKPGEARVEVLATPINPSDILTLSGQYGQLPKLPA
CCCEECCCCCCCHHHHHHHCCCCCEECCCCCEEEEEEECCCCCCEEEECCCCCCCCCCCC
VPGNEGVGRVVEVQDSSAVKVGDIVFLPLGAGTWCTHLVAPADSLLRVPPGTDLRQAAML
CCCCCCCCCEEEECCCCCEEECCEEEEECCCCHHHHHHHCCCHHEEECCCCCCCCCEEEE
FINPPTADLLLRDFIALQPGEWVIQNAANSAVGRSIITLAKQAGFKTLNVVRREELAPEL
EECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHH
TALGADAVLLDSDELPERVREVTGGAKVRLAIDAVGGESTQRLGDALARGGVVVNYGAMS
HHCCCCEEEECCHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHCCEEEEECCCC
GKGPRLSAAATIFKDITLRGFWLVTWTKKTPREEQGALFARLAKQVAEGALHVPVEGTFP
CCCCCHHHHHHHHHHHEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCEECCCCCCCC
LESIQEALTRAMEGGRAGKVLLTPNGPL
HHHHHHHHHHHHCCCCCCEEEECCCCCC
>Mature Secondary Structure
MKAVRFSAFGQPLKVVEVVEQPDVALKPGEARVEVLATPINPSDILTLSGQYGQLPKLPA
CCCEECCCCCCCHHHHHHHCCCCCEECCCCCEEEEEEECCCCCCEEEECCCCCCCCCCCC
VPGNEGVGRVVEVQDSSAVKVGDIVFLPLGAGTWCTHLVAPADSLLRVPPGTDLRQAAML
CCCCCCCCCEEEECCCCCEEECCEEEEECCCCHHHHHHHCCCHHEEECCCCCCCCCEEEE
FINPPTADLLLRDFIALQPGEWVIQNAANSAVGRSIITLAKQAGFKTLNVVRREELAPEL
EECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHH
TALGADAVLLDSDELPERVREVTGGAKVRLAIDAVGGESTQRLGDALARGGVVVNYGAMS
HHCCCCEEEECCHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHCCEEEEECCCC
GKGPRLSAAATIFKDITLRGFWLVTWTKKTPREEQGALFARLAKQVAEGALHVPVEGTFP
CCCCCHHHHHHHHHHHEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCEECCCCCCCC
LESIQEALTRAMEGGRAGKVLLTPNGPL
HHHHHHHHHHHHCCCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 7602590 [H]