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The map label for this gene is gpmA [H]

Identifier: 108762943

GI number: 108762943

Start: 6878826

End: 6879434

Strand: Direct

Name: gpmA [H]

Synonym: MXAN_5529

Alternate gene names: 108762943

Gene position: 6878826-6879434 (Clockwise)

Preceding gene: 108761882

Following gene: 108760376

Centisome position: 75.26

GC content: 68.14

Gene sequence:

>609_bases
ATGCCTACCCTCGTCCTGGTCCGACACGGTCAGTCGCTGTGGAATCAAGAGAACCGCTTCACCGGCCTCGTCGACGTCCC
CCTCACCGACCAGGGGCGCCAGGAGGCCCGGCGCGCGGCGGAGGCGCTGAGCGGGATGACGTTCGACGTCGCCTATACGT
CAGCGCTCATCCGGGCGCAGGAGACGCTGTCCATCCTCTTGGACGCGTTGGGACAGCAGGTCCCCACCATCCGGGACGCC
GCCCTCAACGAGCGCAACTACGGCGACCTGCAGGGGCTCAACAAGGCGGACGCCGCGAAGCGTTGGGGGGCCGCGCAAAT
CAAGGAGTGGCGCCGCTCCTTCGACGTGCCGCCCCCCAACGGCGAGTCCCTGGAGATGACAGCGGAGCGCGTGTTGCCGT
TCTATGAGCGCGCCATCGCCGGAGACCTGCGCCTGGGGAAGAACGTGCTGGTGGTGGCCCACGGCAACTCCAACCGTTCC
CTGGTGATGAAGCTGGACAACCTCACGGGGGAGCAGGTGGTGGGGCTGGAGCTGGCCACCGGGGTGCCGCTCATCTACGA
GATGTCGCCGGACGGAGAGGTGCTGTCCAAGCGCACCGCGTCCCCCTGA

Upstream 100 bases:

>100_bases
AGCCTGAACGAAGCGCGAGACTGTGGAGCCTGGAACGCCCGGCCCCGGGTGGACGCGTACACCCCTGGCCGCCCCAGGGC
TTCTGAATTACCTGAAGGCC

Downstream 100 bases:

>100_bases
CTCAGGTGAAGGCACAGGGGGCTACCCATCCCCCTGGAGTCATGGGATACGCACGGCGGCGCGAGGACGGCTCAGGCCGC
TCCAGGGGGAACTTCCGTGG

Product: putative 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase

Products: NA

Alternate protein names: BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM [H]

Number of amino acids: Translated: 202; Mature: 201

Protein sequence:

>202_residues
MPTLVLVRHGQSLWNQENRFTGLVDVPLTDQGRQEARRAAEALSGMTFDVAYTSALIRAQETLSILLDALGQQVPTIRDA
ALNERNYGDLQGLNKADAAKRWGAAQIKEWRRSFDVPPPNGESLEMTAERVLPFYERAIAGDLRLGKNVLVVAHGNSNRS
LVMKLDNLTGEQVVGLELATGVPLIYEMSPDGEVLSKRTASP

Sequences:

>Translated_202_residues
MPTLVLVRHGQSLWNQENRFTGLVDVPLTDQGRQEARRAAEALSGMTFDVAYTSALIRAQETLSILLDALGQQVPTIRDA
ALNERNYGDLQGLNKADAAKRWGAAQIKEWRRSFDVPPPNGESLEMTAERVLPFYERAIAGDLRLGKNVLVVAHGNSNRS
LVMKLDNLTGEQVVGLELATGVPLIYEMSPDGEVLSKRTASP
>Mature_201_residues
PTLVLVRHGQSLWNQENRFTGLVDVPLTDQGRQEARRAAEALSGMTFDVAYTSALIRAQETLSILLDALGQQVPTIRDAA
LNERNYGDLQGLNKADAAKRWGAAQIKEWRRSFDVPPPNGESLEMTAERVLPFYERAIAGDLRLGKNVLVVAHGNSNRSL
VMKLDNLTGEQVVGLELATGVPLIYEMSPDGEVLSKRTASP

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate [H]

COG id: COG0588

COG function: function code G; Phosphoglycerate mutase 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily [H]

Homologues:

Organism=Homo sapiens, GI50593010, Length=218, Percent_Identity=42.2018348623853, Blast_Score=178, Evalue=3e-45,
Organism=Homo sapiens, GI4505753, Length=218, Percent_Identity=42.6605504587156, Blast_Score=166, Evalue=9e-42,
Organism=Homo sapiens, GI71274132, Length=218, Percent_Identity=39.9082568807339, Blast_Score=152, Evalue=1e-37,
Organism=Homo sapiens, GI4502445, Length=217, Percent_Identity=35.9447004608295, Blast_Score=144, Evalue=6e-35,
Organism=Homo sapiens, GI40353764, Length=217, Percent_Identity=35.9447004608295, Blast_Score=144, Evalue=6e-35,
Organism=Homo sapiens, GI310129614, Length=116, Percent_Identity=51.7241379310345, Blast_Score=118, Evalue=3e-27,
Organism=Escherichia coli, GI1786970, Length=222, Percent_Identity=43.2432432432432, Blast_Score=177, Evalue=5e-46,
Organism=Escherichia coli, GI1786857, Length=184, Percent_Identity=28.2608695652174, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1790856, Length=160, Percent_Identity=31.875, Blast_Score=63, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322697, Length=216, Percent_Identity=43.0555555555556, Blast_Score=167, Evalue=9e-43,
Organism=Saccharomyces cerevisiae, GI6320183, Length=269, Percent_Identity=25.2788104089219, Blast_Score=92, Evalue=7e-20,
Organism=Saccharomyces cerevisiae, GI6324516, Length=265, Percent_Identity=24.9056603773585, Blast_Score=92, Evalue=8e-20,
Organism=Drosophila melanogaster, GI85725270, Length=216, Percent_Identity=42.1296296296296, Blast_Score=171, Evalue=4e-43,
Organism=Drosophila melanogaster, GI85725272, Length=216, Percent_Identity=42.1296296296296, Blast_Score=171, Evalue=4e-43,
Organism=Drosophila melanogaster, GI24650981, Length=216, Percent_Identity=42.1296296296296, Blast_Score=171, Evalue=4e-43,
Organism=Drosophila melanogaster, GI24646216, Length=216, Percent_Identity=40.7407407407407, Blast_Score=170, Evalue=5e-43,
Organism=Drosophila melanogaster, GI28571815, Length=216, Percent_Identity=34.7222222222222, Blast_Score=118, Evalue=2e-27,
Organism=Drosophila melanogaster, GI28571817, Length=216, Percent_Identity=34.7222222222222, Blast_Score=118, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24648979, Length=216, Percent_Identity=34.7222222222222, Blast_Score=118, Evalue=3e-27,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR005952 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 22166; Mature: 22035

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS00175 PG_MUTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTLVLVRHGQSLWNQENRFTGLVDVPLTDQGRQEARRAAEALSGMTFDVAYTSALIRAQ
CCEEEEEECCHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCEEHHHHHHHHHHHH
ETLSILLDALGQQVPTIRDAALNERNYGDLQGLNKADAAKRWGAAQIKEWRRSFDVPPPN
HHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHCCCCCCC
GESLEMTAERVLPFYERAIAGDLRLGKNVLVVAHGNSNRSLVMKLDNLTGEQVVGLELAT
CCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCEEEEEECCCCCCEEEEEEECC
GVPLIYEMSPDGEVLSKRTASP
CCCEEEEECCCHHHHHHCCCCC
>Mature Secondary Structure 
PTLVLVRHGQSLWNQENRFTGLVDVPLTDQGRQEARRAAEALSGMTFDVAYTSALIRAQ
CEEEEEECCHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCEEHHHHHHHHHHHH
ETLSILLDALGQQVPTIRDAALNERNYGDLQGLNKADAAKRWGAAQIKEWRRSFDVPPPN
HHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHCCCCCCC
GESLEMTAERVLPFYERAIAGDLRLGKNVLVVAHGNSNRSLVMKLDNLTGEQVVGLELAT
CCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCEEEEEECCCCCCEEEEEEECC
GVPLIYEMSPDGEVLSKRTASP
CCCEEEEECCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA