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The map label for this gene is clpX [H]

Identifier: 108762916

GI number: 108762916

Start: 3195993

End: 3197192

Strand: Direct

Name: clpX [H]

Synonym: MXAN_2743

Alternate gene names: 108762916

Gene position: 3195993-3197192 (Clockwise)

Preceding gene: 108759917

Following gene: 108760024

Centisome position: 34.97

GC content: 66.92

Gene sequence:

>1200_bases
TTGTGCGGAGGGCAAGCAGGCTGGCGGGGCGGCCGCCCGGTGCTCCTCCTCCCGCGGGCCGACCCTCCATTCAATTCCTA
CCCTTTCCCCGTGAGTCCTGAGGGACGCGTGGAAACAAGGGGAGGGTACATGGAGTCGTCCGCACGCAGGGAAGAGGCGC
TGCTGACCCCGCGGGAAATCTACGAGCGGCTGGATCGCTTCGTCATCGGCCAGGACGGGGCCAAGCGCGCGGTGGCCATT
GCGGCCCACAATCACCTCAAGCGACTGCTGGCGCGAAGGCTGCGCCGGACGTCGCTCATCAAGAAATCCAACATCTTGCT
GATGGGACCCACCGGGAGCGGCAAGACGCACATCGCCCGCAACCTGGCGGACATCCTCCACGTGCCGTTCACCACCGTGG
ACGCCACCGAGTACACGGAGGCCGGCTACTACGGGAAGGACGTGGAGGTGATGATCTCCGACCTCCTCTTCAAGGCGAAC
CACTCCGTGGAGGACACCCAGCGGGGCATCATCTTCATCGACGAGGTGGACAAGATTGCCCGCCGCTCCCAGGGCGCCCG
CAACGGCGCGGGCAGCCGCGACATCGGCGGCGAGGGTGTCCAGCAGTCGCTGCTGAAGCTGCTGGAGGGCCGCGAGGTGT
ACGTACCCCTCAACGTCACCCAGGCCTGGAACAAGAGCGACTTCGTGCAGGTGGACACGCGCGACATCCTCTTCATTTGC
GCGGGCACGTTCAGTGACTTGCACGACGATGGGGATGAAGGGCGCCGCGCCATGGGCTTTGGCGCGGAGGACTCGGCGAA
GCGCAGCCAGAAGCGCATCAGCACCCGCCAGTTGACGGACTTCGGCATGCTGGCGGAGTTCCTCGGCCGTCTGCCGGTGG
TGGTGCAACTGGAGCGGCTGGGCGAGGAGGACCTGATGCGTGTGCTCACCGAGCCGCCGGACTCCATCGTGCGCGAGTTC
CGCGAACTGCTGTCCATGGACGACCTGGAGGTGGACTTCGCCGACCCGGGCCTGCGTGAGGTGGTGCGTTATTCCGTGGA
GCGCGGGCTGGGCGCTCGAGGATTGCGGTCCGTCCTGGAGCACGTCATGGCGGACGTCATGTTCGAGGCGCCCGAGCGGC
GGCGGCGCCAGGTGATGGTGGACGCGGGCTTCGTGCGAGAGCGGCTGCGGGGGCTGGATTCGACGCAGTTGGACGTGTGA

Upstream 100 bases:

>100_bases
GAGGCTCCCTGGGGTAGATGGGGTGGACTCCCGTGAACAACGGACGATCACAGGAATCGCGCGGGAACTATCGGAAAGCC
TCTCGGTATTCAACAGCCGC

Downstream 100 bases:

>100_bases
ATCAGGGCTCGCGCTCGGAGGCGCGGGCCGCGGCGCCCAACCGGGCCGCCACGTCCGGGTCCTGGATGAGCTGGAGCACA
CCGTCGTGGCGCAGCAGCGC

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MCGGQAGWRGGRPVLLLPRADPPFNSYPFPVSPEGRVETRGGYMESSARREEALLTPREIYERLDRFVIGQDGAKRAVAI
AAHNHLKRLLARRLRRTSLIKKSNILLMGPTGSGKTHIARNLADILHVPFTTVDATEYTEAGYYGKDVEVMISDLLFKAN
HSVEDTQRGIIFIDEVDKIARRSQGARNGAGSRDIGGEGVQQSLLKLLEGREVYVPLNVTQAWNKSDFVQVDTRDILFIC
AGTFSDLHDDGDEGRRAMGFGAEDSAKRSQKRISTRQLTDFGMLAEFLGRLPVVVQLERLGEEDLMRVLTEPPDSIVREF
RELLSMDDLEVDFADPGLREVVRYSVERGLGARGLRSVLEHVMADVMFEAPERRRRQVMVDAGFVRERLRGLDSTQLDV

Sequences:

>Translated_399_residues
MCGGQAGWRGGRPVLLLPRADPPFNSYPFPVSPEGRVETRGGYMESSARREEALLTPREIYERLDRFVIGQDGAKRAVAI
AAHNHLKRLLARRLRRTSLIKKSNILLMGPTGSGKTHIARNLADILHVPFTTVDATEYTEAGYYGKDVEVMISDLLFKAN
HSVEDTQRGIIFIDEVDKIARRSQGARNGAGSRDIGGEGVQQSLLKLLEGREVYVPLNVTQAWNKSDFVQVDTRDILFIC
AGTFSDLHDDGDEGRRAMGFGAEDSAKRSQKRISTRQLTDFGMLAEFLGRLPVVVQLERLGEEDLMRVLTEPPDSIVREF
RELLSMDDLEVDFADPGLREVVRYSVERGLGARGLRSVLEHVMADVMFEAPERRRRQVMVDAGFVRERLRGLDSTQLDV
>Mature_399_residues
MCGGQAGWRGGRPVLLLPRADPPFNSYPFPVSPEGRVETRGGYMESSARREEALLTPREIYERLDRFVIGQDGAKRAVAI
AAHNHLKRLLARRLRRTSLIKKSNILLMGPTGSGKTHIARNLADILHVPFTTVDATEYTEAGYYGKDVEVMISDLLFKAN
HSVEDTQRGIIFIDEVDKIARRSQGARNGAGSRDIGGEGVQQSLLKLLEGREVYVPLNVTQAWNKSDFVQVDTRDILFIC
AGTFSDLHDDGDEGRRAMGFGAEDSAKRSQKRISTRQLTDFGMLAEFLGRLPVVVQLERLGEEDLMRVLTEPPDSIVREF
RELLSMDDLEVDFADPGLREVVRYSVERGLGARGLRSVLEHVMADVMFEAPERRRRQVMVDAGFVRERLRGLDSTQLDV

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=317, Percent_Identity=41.9558359621451, Blast_Score=227, Evalue=1e-59,
Organism=Escherichia coli, GI1786642, Length=348, Percent_Identity=42.2413793103448, Blast_Score=271, Evalue=5e-74,
Organism=Escherichia coli, GI1790366, Length=102, Percent_Identity=51.9607843137255, Blast_Score=104, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI71982905, Length=292, Percent_Identity=39.3835616438356, Blast_Score=202, Evalue=3e-52,
Organism=Caenorhabditis elegans, GI71982908, Length=292, Percent_Identity=39.3835616438356, Blast_Score=202, Evalue=3e-52,
Organism=Caenorhabditis elegans, GI71988663, Length=420, Percent_Identity=31.1904761904762, Blast_Score=189, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI71988660, Length=270, Percent_Identity=34.4444444444444, Blast_Score=140, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6319704, Length=425, Percent_Identity=28, Blast_Score=179, Evalue=5e-46,
Organism=Drosophila melanogaster, GI24648291, Length=311, Percent_Identity=40.1929260450161, Blast_Score=224, Evalue=1e-58,
Organism=Drosophila melanogaster, GI24648289, Length=311, Percent_Identity=40.1929260450161, Blast_Score=224, Evalue=1e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 44726; Mature: 44726

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGGQAGWRGGRPVLLLPRADPPFNSYPFPVSPEGRVETRGGYMESSARREEALLTPREI
CCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCEECCCCCHHHHHHHHHHCCCHHHH
YERLDRFVIGQDGAKRAVAIAAHNHLKRLLARRLRRTSLIKKSNILLMGPTGSGKTHIAR
HHHHHHHEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHH
NLADILHVPFTTVDATEYTEAGYYGKDVEVMISDLLFKANHSVEDTQRGIIFIDEVDKIA
HHHHHHHCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHCCCEEEEHHHHHHH
RRSQGARNGAGSRDIGGEGVQQSLLKLLEGREVYVPLNVTQAWNKSDFVQVDTRDILFIC
HHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEECHHHCCCCCCCEEECCCEEEEEE
AGTFSDLHDDGDEGRRAMGFGAEDSAKRSQKRISTRQLTDFGMLAEFLGRLPVVVQLERL
ECCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHC
GEEDLMRVLTEPPDSIVREFRELLSMDDLEVDFADPGLREVVRYSVERGLGARGLRSVLE
CHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHCCCHHHHHHHHH
HVMADVMFEAPERRRRQVMVDAGFVRERLRGLDSTQLDV
HHHHHHHHCCHHHHHHEEHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MCGGQAGWRGGRPVLLLPRADPPFNSYPFPVSPEGRVETRGGYMESSARREEALLTPREI
CCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCEECCCCCHHHHHHHHHHCCCHHHH
YERLDRFVIGQDGAKRAVAIAAHNHLKRLLARRLRRTSLIKKSNILLMGPTGSGKTHIAR
HHHHHHHEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHH
NLADILHVPFTTVDATEYTEAGYYGKDVEVMISDLLFKANHSVEDTQRGIIFIDEVDKIA
HHHHHHHCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHCCCEEEEHHHHHHH
RRSQGARNGAGSRDIGGEGVQQSLLKLLEGREVYVPLNVTQAWNKSDFVQVDTRDILFIC
HHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEECHHHCCCCCCCEEECCCEEEEEE
AGTFSDLHDDGDEGRRAMGFGAEDSAKRSQKRISTRQLTDFGMLAEFLGRLPVVVQLERL
ECCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHC
GEEDLMRVLTEPPDSIVREFRELLSMDDLEVDFADPGLREVVRYSVERGLGARGLRSVLE
CHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHCCCHHHHHHHHH
HVMADVMFEAPERRRRQVMVDAGFVRERLRGLDSTQLDV
HHHHHHHHCCHHHHHHEEHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA