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The map label for this gene is pkwA [H]

Identifier: 108762815

GI number: 108762815

Start: 859316

End: 860959

Strand: Direct

Name: pkwA [H]

Synonym: MXAN_0752

Alternate gene names: 108762815

Gene position: 859316-860959 (Clockwise)

Preceding gene: 108759978

Following gene: 108760772

Centisome position: 9.4

GC content: 73.78

Gene sequence:

>1644_bases
ATGAAGTTCGCGAGGGGGGCGTTCGCACTGCTGGCGGGCGGGGTGGTGGCGGTAGGGGGTGGTGGCTGTGCACACGCGCC
TCCTCGGGTGTCCCCGGAGCTGAGCGCCCGGCTGGAGTCGGAGCCGGGCACCTGGGTGTCCGGTAGCGCCTCGGGCCTTG
GGCGCAAGGCCGTCCTCAACAACAAGGACTTCATCTGGGGCCTGGCCTTCGCGCCCCAAGGCGCCCGGGTGGCGTACTCG
CGCCTGGGCAGCAAGTCCTACTTCCTCTCCGTCTGGGAGCTGGGCTCCGCCGAGCCGACGATGCTGGCGGACCCGGCCAT
CAACCCCTACGAGTTCGACGTGGAGGGCGTGGCCTTCTCCCCGGATGGCACGCGCGTGGCCACCGCGGGCAAGGACAGCG
TGGTGCGCCTCTTCGACGCGGCCACCGGCGCGCTCGTGGCGGAGCGCCGCACCGAGGAACCGCTGTCCGTGGTGGCCTTC
CACCCGGAGGGGCAGTGGCTGGTGGTGGGCAGCTACAAGGGACTGATGACGGTGTTGTCGGCGCCCGCGCTGGAGTACGG
CTCCGAGGAGCGCGGACACCTGGGGCCGGTGACGGCGCTGGCCTTCGCGCCGGACGGGACGCTGTATTCGGGCGGCTGGG
ACAAGCACGTGCGGGCCTGGCGCACCTCCGTGGAGGGGCTGCGGCCGGGGCAGGCGCGCATGCGCTTCGAGCGGCGCGCC
GGCTCCGTGGTGCTGGGCGGCACGGTGAATGACAAGGCGCCGCTGTCCTTCGCGTTGGATGCGCGCGCGCCCGCGCTGGT
GCTCACCAGCGAGGCGGCCGCCGCGGCGGGCATCGACGTGCCCTTCTTGAAGGAGACGGTCAACGTGCCGGGGCCGCTGG
GCACCATCGCCGCGCGGCTGGCGCCGGCCCAGTCCCTGCGCTTCAAGTCCATGCGGGTGGAGGGCGTAGACGTCGCCATC
TGTGACGCGTGCGTGCCGCAGGGCACCCAGGGCGTGCTGGGCGCGCCCTTCTCCGAACGGGTGGACGTGGCCTTCGACGA
AGTCACGCAGGAGGCCGTGCTGTCGCTGAAGGGCGGCCCGCCCGAGGGCGCGGTGACGGTGGACGCGCTGGTGCTCGCGC
GGCGCTCGGAGTTTCCCTTCCCGGCCTACGTGAGCGACGTCACCGTGGACGCGCGCGGCCAGAGGCTGGGGGTGGGGCTG
TCGGAGCAGAAGCCGGAGCGCGACCGCGGCGTGTACGAGCGCGAGCGCAAGGGCGTGGAGGAGCCGCAGGGCCCCTTCAA
CGCGGGCGCGCTGGTGGACGCGCAGTCCGGTCAGGTGCTGGCGAAGTGGCCGGTGCACCGGGGCGTGGTGGCCACCGCGG
CCATCTCCCCGGACGGGCGCTCGCTGGCCAGCGGCGGCTGGGACAAGCGCGTGTACCTGTTCACCGAAGGGGACGTGGAC
GCGCGCGGCGAGCACCGCTTCGACTGGTCCGTGCGGCGCGTGCGCTTCAGCCCGGATGGGCGCTGGCTGGGCGTGGCCGC
GTGGACGCCCCAGGTGGCCAGCCGCGACGGGGACAGCGACCCGGCGGCGGTGCTGCTGGACGTGGGCTATGAATCGCCCA
CTGTGCAGGGGCCGGGCACGGCCGGCGCGTCCGTCGCTCCGTAG

Upstream 100 bases:

>100_bases
AGCAGCTGTTCCTGTTGTCCATCGACAACAAGGGCGTCACGGAAATCAACGTCGAGAAGGAGCGGCAGAAGGCCGCCTCG
GCGTCAGGAGGCTCAGGGAC

Downstream 100 bases:

>100_bases
TCCTCACTCCACCGCTCAGAAGTTGAGGTGGATGTCACCCGCGGGCATGCCGCGGGCCTGGAGCGTCGTCATCACGCCCC
GCACCATCTCCTTCTGCCCG

Product: WD domain-/G-beta repeat-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 547; Mature: 547

Protein sequence:

>547_residues
MKFARGAFALLAGGVVAVGGGGCAHAPPRVSPELSARLESEPGTWVSGSASGLGRKAVLNNKDFIWGLAFAPQGARVAYS
RLGSKSYFLSVWELGSAEPTMLADPAINPYEFDVEGVAFSPDGTRVATAGKDSVVRLFDAATGALVAERRTEEPLSVVAF
HPEGQWLVVGSYKGLMTVLSAPALEYGSEERGHLGPVTALAFAPDGTLYSGGWDKHVRAWRTSVEGLRPGQARMRFERRA
GSVVLGGTVNDKAPLSFALDARAPALVLTSEAAAAAGIDVPFLKETVNVPGPLGTIAARLAPAQSLRFKSMRVEGVDVAI
CDACVPQGTQGVLGAPFSERVDVAFDEVTQEAVLSLKGGPPEGAVTVDALVLARRSEFPFPAYVSDVTVDARGQRLGVGL
SEQKPERDRGVYERERKGVEEPQGPFNAGALVDAQSGQVLAKWPVHRGVVATAAISPDGRSLASGGWDKRVYLFTEGDVD
ARGEHRFDWSVRRVRFSPDGRWLGVAAWTPQVASRDGDSDPAAVLLDVGYESPTVQGPGTAGASVAP

Sequences:

>Translated_547_residues
MKFARGAFALLAGGVVAVGGGGCAHAPPRVSPELSARLESEPGTWVSGSASGLGRKAVLNNKDFIWGLAFAPQGARVAYS
RLGSKSYFLSVWELGSAEPTMLADPAINPYEFDVEGVAFSPDGTRVATAGKDSVVRLFDAATGALVAERRTEEPLSVVAF
HPEGQWLVVGSYKGLMTVLSAPALEYGSEERGHLGPVTALAFAPDGTLYSGGWDKHVRAWRTSVEGLRPGQARMRFERRA
GSVVLGGTVNDKAPLSFALDARAPALVLTSEAAAAAGIDVPFLKETVNVPGPLGTIAARLAPAQSLRFKSMRVEGVDVAI
CDACVPQGTQGVLGAPFSERVDVAFDEVTQEAVLSLKGGPPEGAVTVDALVLARRSEFPFPAYVSDVTVDARGQRLGVGL
SEQKPERDRGVYERERKGVEEPQGPFNAGALVDAQSGQVLAKWPVHRGVVATAAISPDGRSLASGGWDKRVYLFTEGDVD
ARGEHRFDWSVRRVRFSPDGRWLGVAAWTPQVASRDGDSDPAAVLLDVGYESPTVQGPGTAGASVAP
>Mature_547_residues
MKFARGAFALLAGGVVAVGGGGCAHAPPRVSPELSARLESEPGTWVSGSASGLGRKAVLNNKDFIWGLAFAPQGARVAYS
RLGSKSYFLSVWELGSAEPTMLADPAINPYEFDVEGVAFSPDGTRVATAGKDSVVRLFDAATGALVAERRTEEPLSVVAF
HPEGQWLVVGSYKGLMTVLSAPALEYGSEERGHLGPVTALAFAPDGTLYSGGWDKHVRAWRTSVEGLRPGQARMRFERRA
GSVVLGGTVNDKAPLSFALDARAPALVLTSEAAAAAGIDVPFLKETVNVPGPLGTIAARLAPAQSLRFKSMRVEGVDVAI
CDACVPQGTQGVLGAPFSERVDVAFDEVTQEAVLSLKGGPPEGAVTVDALVLARRSEFPFPAYVSDVTVDARGQRLGVGL
SEQKPERDRGVYERERKGVEEPQGPFNAGALVDAQSGQVLAKWPVHRGVVATAAISPDGRSLASGGWDKRVYLFTEGDVD
ARGEHRFDWSVRRVRFSPDGRWLGVAAWTPQVASRDGDSDPAAVLLDVGYESPTVQGPGTAGASVAP

Specific function: May play a regulatory role during the complex growth cycle and in secondary metabolite production [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 7 WD repeats [H]

Homologues:

Organism=Homo sapiens, GI26665869, Length=114, Percent_Identity=32.4561403508772, Blast_Score=70, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020472
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017441
- InterPro:   IPR017442
- InterPro:   IPR008271
- InterPro:   IPR015943
- InterPro:   IPR001680
- InterPro:   IPR011046
- InterPro:   IPR019782
- InterPro:   IPR019775
- InterPro:   IPR017986
- InterPro:   IPR019781 [H]

Pfam domain/function: PF00069 Pkinase; PF00400 WD40 [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 57483; Mature: 57483

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS01047 HMA_1 ; PS50082 WD_REPEATS_2 ; PS50294 WD_REPEATS_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFARGAFALLAGGVVAVGGGGCAHAPPRVSPELSARLESEPGTWVSGSASGLGRKAVLN
CCCCHHHHHHHHCCEEEECCCCCCCCCCCCCHHHHHEECCCCCCEECCCCCCCCCEEEEC
NKDFIWGLAFAPQGARVAYSRLGSKSYFLSVWELGSAEPTMLADPAINPYEFDVEGVAFS
CCCEEEEEEECCCCCHHHHHHCCCCEEEEEEEECCCCCCCEEECCCCCCEEEEEEEEEEC
PDGTRVATAGKDSVVRLFDAATGALVAERRTEEPLSVVAFHPEGQWLVVGSYKGLMTVLS
CCCCEEEECCCCCEEEEEHHHCCHHHHHCCCCCCCEEEEECCCCCEEEEECCHHHHHHHH
APALEYGSEERGHLGPVTALAFAPDGTLYSGGWDKHVRAWRTSVEGLRPGQARMRFERRA
CCHHHCCCCCCCCCCCEEEEEECCCCCEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHCC
GSVVLGGTVNDKAPLSFALDARAPALVLTSEAAAAAGIDVPFLKETVNVPGPLGTIAARL
CCEEECCCCCCCCCEEEEECCCCCEEEEECCCHHHCCCCCHHHHHHCCCCCCHHHHHHHH
APAQSLRFKSMRVEGVDVAICDACVPQGTQGVLGAPFSERVDVAFDEVTQEAVLSLKGGP
CCHHHHEEEEEEECCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEECCCC
PEGAVTVDALVLARRSEFPFPAYVSDVTVDARGQRLGVGLSEQKPERDRGVYERERKGVE
CCCCEEHHHHHHHHCCCCCCCCEEEEEEEECCCCEECCCCCCCCCCHHCCHHHHHHCCCC
EPQGPFNAGALVDAQSGQVLAKWPVHRGVVATAAISPDGRSLASGGWDKRVYLFTEGDVD
CCCCCCCCCEEEECCCCCEEEECCCCCCEEEEEEECCCCCHHCCCCCCCEEEEEECCCCC
ARGEHRFDWSVRRVRFSPDGRWLGVAAWTPQVASRDGDSDPAAVLLDVGYESPTVQGPGT
CCCCEEECEEEEEEEECCCCCEEEEEECCCHHHCCCCCCCCEEEEEEECCCCCCCCCCCC
AGASVAP
CCCCCCC
>Mature Secondary Structure
MKFARGAFALLAGGVVAVGGGGCAHAPPRVSPELSARLESEPGTWVSGSASGLGRKAVLN
CCCCHHHHHHHHCCEEEECCCCCCCCCCCCCHHHHHEECCCCCCEECCCCCCCCCEEEEC
NKDFIWGLAFAPQGARVAYSRLGSKSYFLSVWELGSAEPTMLADPAINPYEFDVEGVAFS
CCCEEEEEEECCCCCHHHHHHCCCCEEEEEEEECCCCCCCEEECCCCCCEEEEEEEEEEC
PDGTRVATAGKDSVVRLFDAATGALVAERRTEEPLSVVAFHPEGQWLVVGSYKGLMTVLS
CCCCEEEECCCCCEEEEEHHHCCHHHHHCCCCCCCEEEEECCCCCEEEEECCHHHHHHHH
APALEYGSEERGHLGPVTALAFAPDGTLYSGGWDKHVRAWRTSVEGLRPGQARMRFERRA
CCHHHCCCCCCCCCCCEEEEEECCCCCEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHCC
GSVVLGGTVNDKAPLSFALDARAPALVLTSEAAAAAGIDVPFLKETVNVPGPLGTIAARL
CCEEECCCCCCCCCEEEEECCCCCEEEEECCCHHHCCCCCHHHHHHCCCCCCHHHHHHHH
APAQSLRFKSMRVEGVDVAICDACVPQGTQGVLGAPFSERVDVAFDEVTQEAVLSLKGGP
CCHHHHEEEEEEECCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEECCCC
PEGAVTVDALVLARRSEFPFPAYVSDVTVDARGQRLGVGLSEQKPERDRGVYERERKGVE
CCCCEEHHHHHHHHCCCCCCCCEEEEEEEECCCCEECCCCCCCCCCHHCCHHHHHHCCCC
EPQGPFNAGALVDAQSGQVLAKWPVHRGVVATAAISPDGRSLASGGWDKRVYLFTEGDVD
CCCCCCCCCEEEECCCCCEEEECCCCCCEEEEEEECCCCCHHCCCCCCCEEEEEECCCCC
ARGEHRFDWSVRRVRFSPDGRWLGVAAWTPQVASRDGDSDPAAVLLDVGYESPTVQGPGT
CCCCEEECEEEEEEEECCCCCEEEEEECCCHHHCCCCCCCCEEEEEEECCCCCCCCCCCC
AGASVAP
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8631732 [H]