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The map label for this gene is pcbC [H]

Identifier: 108762760

GI number: 108762760

Start: 1726401

End: 1727363

Strand: Reverse

Name: pcbC [H]

Synonym: MXAN_1466

Alternate gene names: 108762760

Gene position: 1727363-1726401 (Counterclockwise)

Preceding gene: 108762892

Following gene: 108761200

Centisome position: 18.9

GC content: 68.12

Gene sequence:

>963_bases
ATGTCGCCAACCCAGCGCCGCATCCCCGTCGTCAACCTGTCCCATTACCGCACGGGCACACCCCAGGAGCGCGCCCGCTT
CGTGCAGGTGTTCGGCGACGGCATCAAGGAGTTCGGCTTCGTCACGGTGGAAGGCCACGGCATCGACGACGGCCTCATCC
GGCGCACGTACACGGACGTGGAGCGCTTCTTCGCCCTGCCCGAGGCCACCAAGGCCCAGTACGCCCAGGCGGGGCACGGC
GGCCAGCGCGGCTACATCGGCTACGGTCAGGAGCACGCGAAGAACCGCCAGGTGGGAGACCTGAAGGAGTTCTGGCACGT
GGGCCGCGAGCTCCCACCTGACCACAAGTACCACGCGCTCTATGGCCCCAACGTGTGGCCCACCGAGGTGTCCACCTTCC
GCGAGCACACGCTGTCGCTCTTCAACGCGCTGGATGGCGCGGCGGGCGTCATGCTCCAGGCGCTGGCCGAGTACTTCGGC
GTGGCGCGCGACACCTTCAGCGGCATGGCCACGGACGGCAACTCCGTGCTGCGGCTCATCCACTACCCGCCGCTGAAGGA
GCGCTTCATCCCCGGGGGCGTGCGCGCCGCCGAGCATGAGGACATCAACCTCATCACCCTCCTCTGCGAGGGCACGGCGT
CCGGCCTGGAGCTGCTCACCCGCGACGGGGAGTGGCTGCCGGTGGACACACTGCGCGGACAGATTGTCGTCGACTCGGGC
GACATGCTCAGCCGCGTGACGAACGAAATCATCCCCGCCACTACGCACCGGGTGGTGAACCCGCGCAGCAAGGAAGAGGA
CACGGTGCGCTACTCGATGCCCTTCTTCGTCCATCCCTACGCGGACTGCGTGCTCCAGGCGCTGCCCTGCACCCAGACGG
CGGACACCCCGGCGCGCCACGCGCCCATCACCGCGGATGCCTTCCTCAAGCAGCGGCTGCGCGAGAATGGCTTGCTGAAG
TAA

Upstream 100 bases:

>100_bases
CCGCTGGTGCCGCACCCTCGAAGCCATGGTCGCAGAACAGGGTCCTCTGGCGGACGCTGTGCGTGCCGACAATCCATCAC
GGTGGTTAAAGTGCGGCGCC

Downstream 100 bases:

>100_bases
CGCACCGTGGACACGGCCACCGACCTCGTCGAACTGTTCGCCCTCCAGCCCCGCGTCTCGCTGGAGGACTACGCCTCTCC
GGCGGCCTTCGCCGCGCGAC

Product: 2OG-Fe(II) oxygenase family oxidoreductase

Products: NA

Alternate protein names: IPNS [H]

Number of amino acids: Translated: 320; Mature: 319

Protein sequence:

>320_residues
MSPTQRRIPVVNLSHYRTGTPQERARFVQVFGDGIKEFGFVTVEGHGIDDGLIRRTYTDVERFFALPEATKAQYAQAGHG
GQRGYIGYGQEHAKNRQVGDLKEFWHVGRELPPDHKYHALYGPNVWPTEVSTFREHTLSLFNALDGAAGVMLQALAEYFG
VARDTFSGMATDGNSVLRLIHYPPLKERFIPGGVRAAEHEDINLITLLCEGTASGLELLTRDGEWLPVDTLRGQIVVDSG
DMLSRVTNEIIPATTHRVVNPRSKEEDTVRYSMPFFVHPYADCVLQALPCTQTADTPARHAPITADAFLKQRLRENGLLK

Sequences:

>Translated_320_residues
MSPTQRRIPVVNLSHYRTGTPQERARFVQVFGDGIKEFGFVTVEGHGIDDGLIRRTYTDVERFFALPEATKAQYAQAGHG
GQRGYIGYGQEHAKNRQVGDLKEFWHVGRELPPDHKYHALYGPNVWPTEVSTFREHTLSLFNALDGAAGVMLQALAEYFG
VARDTFSGMATDGNSVLRLIHYPPLKERFIPGGVRAAEHEDINLITLLCEGTASGLELLTRDGEWLPVDTLRGQIVVDSG
DMLSRVTNEIIPATTHRVVNPRSKEEDTVRYSMPFFVHPYADCVLQALPCTQTADTPARHAPITADAFLKQRLRENGLLK
>Mature_319_residues
SPTQRRIPVVNLSHYRTGTPQERARFVQVFGDGIKEFGFVTVEGHGIDDGLIRRTYTDVERFFALPEATKAQYAQAGHGG
QRGYIGYGQEHAKNRQVGDLKEFWHVGRELPPDHKYHALYGPNVWPTEVSTFREHTLSLFNALDGAAGVMLQALAEYFGV
ARDTFSGMATDGNSVLRLIHYPPLKERFIPGGVRAAEHEDINLITLLCEGTASGLELLTRDGEWLPVDTLRGQIVVDSGD
MLSRVTNEIIPATTHRVVNPRSKEEDTVRYSMPFFVHPYADCVLQALPCTQTADTPARHAPITADAFLKQRLRENGLLK

Specific function: Removes, in the presence of oxygen, 4 hydrogen atoms from delta-L-(alpha-aminoadipyl)-L-cysteinyl-D-valine (ACV) to form the azetidinone and thiazolidine rings of isopenicillin [H]

COG id: COG3491

COG function: function code R; Isopenicillin N synthase and related dioxygenases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Fe2OG dioxygenase domain [H]

Homologues:

Organism=Drosophila melanogaster, GI28572124, Length=288, Percent_Identity=25.3472222222222, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI85816264, Length=287, Percent_Identity=23.3449477351916, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002057
- InterPro:   IPR002283
- InterPro:   IPR005123 [H]

Pfam domain/function: PF03171 2OG-FeII_Oxy [H]

EC number: =1.21.3.1 [H]

Molecular weight: Translated: 35726; Mature: 35595

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPTQRRIPVVNLSHYRTGTPQERARFVQVFGDGIKEFGFVTVEGHGIDDGLIRRTYTDV
CCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHH
ERFFALPEATKAQYAQAGHGGQRGYIGYGQEHAKNRQVGDLKEFWHVGRELPPDHKYHAL
HHHHCCCCHHHHHHHHCCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHCCCCCCCCCEEEE
YGPNVWPTEVSTFREHTLSLFNALDGAAGVMLQALAEYFGVARDTFSGMATDGNSVLRLI
ECCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEE
HYPPLKERFIPGGVRAAEHEDINLITLLCEGTASGLELLTRDGEWLPVDTLRGQIVVDSG
ECCCHHHHCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHCCCCEEEHHCCCCEEEECCC
DMLSRVTNEIIPATTHRVVNPRSKEEDTVRYSMPFFVHPYADCVLQALPCTQTADTPARH
HHHHHHHHHHCCCHHHHHCCCCCCCCCCEEEECCEEECHHHHHHHHHCCCCCCCCCCCCC
APITADAFLKQRLRENGLLK
CCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SPTQRRIPVVNLSHYRTGTPQERARFVQVFGDGIKEFGFVTVEGHGIDDGLIRRTYTDV
CCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHH
ERFFALPEATKAQYAQAGHGGQRGYIGYGQEHAKNRQVGDLKEFWHVGRELPPDHKYHAL
HHHHCCCCHHHHHHHHCCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHCCCCCCCCCEEEE
YGPNVWPTEVSTFREHTLSLFNALDGAAGVMLQALAEYFGVARDTFSGMATDGNSVLRLI
ECCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEE
HYPPLKERFIPGGVRAAEHEDINLITLLCEGTASGLELLTRDGEWLPVDTLRGQIVVDSG
ECCCHHHHCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHCCCCEEEHHCCCCEEEECCC
DMLSRVTNEIIPATTHRVVNPRSKEEDTVRYSMPFFVHPYADCVLQALPCTQTADTPARH
HHHHHHHHHHCCCHHHHHCCCCCCCCCCEEEECCEEECHHHHHHHHHCCCCCCCCCCCCC
APITADAFLKQRLRENGLLK
CCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1901702 [H]