Click here to switch to the map view.

The map label for this gene is 108762750

Identifier: 108762750

GI number: 108762750

Start: 1158508

End: 1161117

Strand: Direct

Name: 108762750

Synonym: MXAN_0998

Alternate gene names: NA

Gene position: 1158508-1161117 (Clockwise)

Preceding gene: 108758313

Following gene: 108759732

Centisome position: 12.68

GC content: 70.0

Gene sequence:

>2610_bases
ATGCTAGGGTGCCGCCCCTTTCGCTTCTTCCGAGGGGTCGCCCGAATGCGTCGCCTGCTGTTGATGGGACTGTTGCTGCT
CTCCGTTACCTCCTGTTCAGGCGACGACGAAGACCCGGGGGAGCAGTCCTCCAGGACCGGGCGCATCCAGGGGACGCTGA
CGCCTTTCCGGAGCAGCGAACGGTCCGCAGGCGACGGTGCCTCCCAGACGGTGCGCTCGCCGTTTCGCGCGGGTGAGCTG
GAGAAGCTGAAGGAGACGCTGCGGGGGATGCACGCGGGACGCTCGCGCGAGCCGCGGGTGGCGCCGAAGGCCATGCCGGG
GCTTCCCATCATCCCGTCGCAGCCGGCCGCCGCGCCGCTCGAGCGGGCCTCTCGCGAGGACCCCACGATTCCCGGAGACG
TCATCCTCCGCTTCGAGGAAGCGGGCCTGACACCGGAGCGCGTGCTGGCGGCGGTGCAGCGCCCGGGCTTCCGCGCGGTG
CACAAGGGCTACGCGAGTGAGTACGTGCACCTGGTGGGCTACGAGCCGCTGGACGGCAAGGCGGTGACGGCCGCGAAGAC
GCAGGAGTGGGCGGCGCAGCTCGCCCAGGTGCCGGGCGTGACGTATGCGGTGCGCAACGAGCGGATGCGGGCGACGGCGG
CGCCGAATGACCGGGGCTACAGCCTTCAGTGGCACTACCCCACGCTCAACCTGCCGGCCGCGTGGGACCTGGTGCCGGAC
GCGTCCAGCGTGGTGGTGGCCGTCCTCGACAGCGGCATCGTTCCGCACCCGGACCTGACGAATGTGTTGCCGGGTTACGA
CATGATTTCGGACCCGGAGAACGCGGGTGACGGCGATGGCCGGGACAGCAATCCGCGGGACGAAGGTGGGGACACGCCCA
GCGGCGGCTCGACGTGGCACGGCTCGCATGTGGCGGGCACCATCGCCGCGGACACGAACAACCAGGTGGGCGTCGCGGGC
GTGGCCTGGAACGCCCGGCTGCTCCCAGTGAGGGTGCTGGGGAAGAAGGGCGGGAGCAGCTTCGACATCGCCGCGGCCAT
CACCTGGGCCACGGGCGGCCCCGTGCCGGGCGTACCGCCCAATCCCAATCCCGCGAAGGTGGTGAACATGAGCCTGGGTG
GCCGCGCGCCGCCGCAGGCGCTGTACCAGGACGCCATCGACGCGGCCTTGGGACGCGGGGCCATCATCGTCGTCGCCGCG
GGCAATGAGGACGTGGATGCGCGCACCAGCACGCCGTGCAACCAGCAGAACGTCGTCTGTGTGGGCTCCACCAGTCTTGC
GGGCCAGCGCAGCAGCTTCTCCAACTACGGCGTGGACGTGGACGTGGTGGCGTCTGGTGGGGAGATGCGCGAGGACCTGA
ACGGCGACGGCTATCCGGACGGCGTGCTGTCCACGGTGCTGGATGAGAACGGGCAGCCTGCCTATGCCTTCTCGCAGGGC
ACCAGCATGGCGGCGCCTCACGTCACGGGCGTGGTGGCGCTGATGGCGGCGTCGCGGCCGGACCTGACGGCCGCGCTGGC
GGAGCGCATCTTGAAGGAAACCGCTACGCCGCTCACCAACGCGCAGTGCCCGGAGGGCTGCGGCGCGGGGCTCGTCAACG
CGCGAGCGGCGCTGGCCCGCATCGCCAACGTGGACCCTGGCACGTTGGACCCTCAGCTTAACGTGACGACGTCCACACTG
TTCTTCCGGGGCAGCGGGACGCAGCCGCTCATTCTCAGCAACGTGGGCGGGAACCGGGGCGGCGATTTGACGGTATCGGC
CAGCGTCAGTGGGCCCAATGCCTCGGCGGTGTCATTCCCGCAGGGCAACACGGTGCGGGTACCCGCCTTCAGCTCGGCCC
CGTTGAGTGTGGCGGTGGATGCATCCGGGCTGGCCGGAGGGGACACCGTGGTGACGCTGAGCCTGGTGGGCTCGGGGACG
GCGGGCTCGGCGACGGTGGCGGTGAAGATTGGCGTGGCGGGCGCAGCCAATGACCTGGACGCCCTGATTGCGTTCGTGTG
GCAGGACGCGCGAGGGGAGTGGCAGGCCTCGAAGGACGCCATCGCGGTCGCGCGCGCCTCGGCGGACTACGCGTACAGCA
TCTCCCTGGCGCCGCGGACGTACTTCGCGTTGGCCACCATCGACGACGACCAGGATGGCAACTTCTTCGAGGACGGCGAG
CGCACCGGCTACTGGCGCAACGTGGACTCCTTCGAGCCGCTGGAGCTGGAGGCGGGTGACCGCATCGAGAATGTGAGCTT
CGACCTGATTCCCCTGGCGCCCATCGATGATGACCCGGCGCTGGTGGTGGGCAGTGCGTGCGGCTCCAACGTGGACTGTC
CCGGGGGCGTGTGCGTGACGGACTATCCGGGCGGGTACTGCTCCATGGATTGCACCAGCTCCGCGTGTCCGGCGGGCTCG
CGGTGTTACATCGTGGATTCCTCCTCGGGCCTCAAGGCATGTCTGGCGACCTGCACGCGGCAGGTGGGAACGGGGCAGGG
GGACTGCCGCCCCGGGTACGTCTGCTACAGCGACGGCACGGGTTCGGGAGCGTGCCAGCCCAACTGCCGCACCTCTGGCC
TGACGTGTGGGCTGGGACGGACGTGCACGGCCAGCGGCTTCTGTCGCTGA

Upstream 100 bases:

>100_bases
GGCGCACTGGACGATACGGCCGACGGCAACGTTGGAGAAGACACGGAAGATGGCGGCGAGGCGATGGCGAGCTGAGTGGT
GAGGTCCCGTCGGGCAGCGG

Downstream 100 bases:

>100_bases
GGAAGGCTCGAGAGCCCGTGTCCAGAGCGGCCGAGGGGGAGAGCGGTGGACACTTGGCCACAGTTCCCAATTCCCACCGG
GCAGCGACAGCGGCATCGTG

Product: S8A family peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 869; Mature: 869

Protein sequence:

>869_residues
MLGCRPFRFFRGVARMRRLLLMGLLLLSVTSCSGDDEDPGEQSSRTGRIQGTLTPFRSSERSAGDGASQTVRSPFRAGEL
EKLKETLRGMHAGRSREPRVAPKAMPGLPIIPSQPAAAPLERASREDPTIPGDVILRFEEAGLTPERVLAAVQRPGFRAV
HKGYASEYVHLVGYEPLDGKAVTAAKTQEWAAQLAQVPGVTYAVRNERMRATAAPNDRGYSLQWHYPTLNLPAAWDLVPD
ASSVVVAVLDSGIVPHPDLTNVLPGYDMISDPENAGDGDGRDSNPRDEGGDTPSGGSTWHGSHVAGTIAADTNNQVGVAG
VAWNARLLPVRVLGKKGGSSFDIAAAITWATGGPVPGVPPNPNPAKVVNMSLGGRAPPQALYQDAIDAALGRGAIIVVAA
GNEDVDARTSTPCNQQNVVCVGSTSLAGQRSSFSNYGVDVDVVASGGEMREDLNGDGYPDGVLSTVLDENGQPAYAFSQG
TSMAAPHVTGVVALMAASRPDLTAALAERILKETATPLTNAQCPEGCGAGLVNARAALARIANVDPGTLDPQLNVTTSTL
FFRGSGTQPLILSNVGGNRGGDLTVSASVSGPNASAVSFPQGNTVRVPAFSSAPLSVAVDASGLAGGDTVVTLSLVGSGT
AGSATVAVKIGVAGAANDLDALIAFVWQDARGEWQASKDAIAVARASADYAYSISLAPRTYFALATIDDDQDGNFFEDGE
RTGYWRNVDSFEPLELEAGDRIENVSFDLIPLAPIDDDPALVVGSACGSNVDCPGGVCVTDYPGGYCSMDCTSSACPAGS
RCYIVDSSSGLKACLATCTRQVGTGQGDCRPGYVCYSDGTGSGACQPNCRTSGLTCGLGRTCTASGFCR

Sequences:

>Translated_869_residues
MLGCRPFRFFRGVARMRRLLLMGLLLLSVTSCSGDDEDPGEQSSRTGRIQGTLTPFRSSERSAGDGASQTVRSPFRAGEL
EKLKETLRGMHAGRSREPRVAPKAMPGLPIIPSQPAAAPLERASREDPTIPGDVILRFEEAGLTPERVLAAVQRPGFRAV
HKGYASEYVHLVGYEPLDGKAVTAAKTQEWAAQLAQVPGVTYAVRNERMRATAAPNDRGYSLQWHYPTLNLPAAWDLVPD
ASSVVVAVLDSGIVPHPDLTNVLPGYDMISDPENAGDGDGRDSNPRDEGGDTPSGGSTWHGSHVAGTIAADTNNQVGVAG
VAWNARLLPVRVLGKKGGSSFDIAAAITWATGGPVPGVPPNPNPAKVVNMSLGGRAPPQALYQDAIDAALGRGAIIVVAA
GNEDVDARTSTPCNQQNVVCVGSTSLAGQRSSFSNYGVDVDVVASGGEMREDLNGDGYPDGVLSTVLDENGQPAYAFSQG
TSMAAPHVTGVVALMAASRPDLTAALAERILKETATPLTNAQCPEGCGAGLVNARAALARIANVDPGTLDPQLNVTTSTL
FFRGSGTQPLILSNVGGNRGGDLTVSASVSGPNASAVSFPQGNTVRVPAFSSAPLSVAVDASGLAGGDTVVTLSLVGSGT
AGSATVAVKIGVAGAANDLDALIAFVWQDARGEWQASKDAIAVARASADYAYSISLAPRTYFALATIDDDQDGNFFEDGE
RTGYWRNVDSFEPLELEAGDRIENVSFDLIPLAPIDDDPALVVGSACGSNVDCPGGVCVTDYPGGYCSMDCTSSACPAGS
RCYIVDSSSGLKACLATCTRQVGTGQGDCRPGYVCYSDGTGSGACQPNCRTSGLTCGLGRTCTASGFCR
>Mature_869_residues
MLGCRPFRFFRGVARMRRLLLMGLLLLSVTSCSGDDEDPGEQSSRTGRIQGTLTPFRSSERSAGDGASQTVRSPFRAGEL
EKLKETLRGMHAGRSREPRVAPKAMPGLPIIPSQPAAAPLERASREDPTIPGDVILRFEEAGLTPERVLAAVQRPGFRAV
HKGYASEYVHLVGYEPLDGKAVTAAKTQEWAAQLAQVPGVTYAVRNERMRATAAPNDRGYSLQWHYPTLNLPAAWDLVPD
ASSVVVAVLDSGIVPHPDLTNVLPGYDMISDPENAGDGDGRDSNPRDEGGDTPSGGSTWHGSHVAGTIAADTNNQVGVAG
VAWNARLLPVRVLGKKGGSSFDIAAAITWATGGPVPGVPPNPNPAKVVNMSLGGRAPPQALYQDAIDAALGRGAIIVVAA
GNEDVDARTSTPCNQQNVVCVGSTSLAGQRSSFSNYGVDVDVVASGGEMREDLNGDGYPDGVLSTVLDENGQPAYAFSQG
TSMAAPHVTGVVALMAASRPDLTAALAERILKETATPLTNAQCPEGCGAGLVNARAALARIANVDPGTLDPQLNVTTSTL
FFRGSGTQPLILSNVGGNRGGDLTVSASVSGPNASAVSFPQGNTVRVPAFSSAPLSVAVDASGLAGGDTVVTLSLVGSGT
AGSATVAVKIGVAGAANDLDALIAFVWQDARGEWQASKDAIAVARASADYAYSISLAPRTYFALATIDDDQDGNFFEDGE
RTGYWRNVDSFEPLELEAGDRIENVSFDLIPLAPIDDDPALVVGSACGSNVDCPGGVCVTDYPGGYCSMDCTSSACPAGS
RCYIVDSSSGLKACLATCTRQVGTGQGDCRPGYVCYSDGTGSGACQPNCRTSGLTCGLGRTCTASGFCR

Specific function: Unknown

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

Organism=Homo sapiens, GI20336180, Length=301, Percent_Identity=26.2458471760797, Blast_Score=70, Evalue=1e-11,
Organism=Homo sapiens, GI4505577, Length=301, Percent_Identity=26.2458471760797, Blast_Score=70, Evalue=1e-11,
Organism=Homo sapiens, GI20336184, Length=301, Percent_Identity=26.2458471760797, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI20336182, Length=301, Percent_Identity=26.2458471760797, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI27894285, Length=313, Percent_Identity=26.1980830670927, Blast_Score=67, Evalue=7e-11,
Organism=Homo sapiens, GI20336188, Length=313, Percent_Identity=26.1980830670927, Blast_Score=67, Evalue=8e-11,
Organism=Homo sapiens, GI20336190, Length=313, Percent_Identity=26.1980830670927, Blast_Score=67, Evalue=8e-11,
Organism=Homo sapiens, GI20336186, Length=313, Percent_Identity=26.1980830670927, Blast_Score=67, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI71983555, Length=382, Percent_Identity=26.1780104712042, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25141268, Length=382, Percent_Identity=26.1780104712042, Blast_Score=71, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6320775, Length=328, Percent_Identity=30.7926829268293, Blast_Score=92, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6324576, Length=204, Percent_Identity=30.8823529411765, Blast_Score=82, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6319893, Length=269, Percent_Identity=28.2527881040892, Blast_Score=79, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007280
- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500 [H]

Pfam domain/function: PF00082 Peptidase_S8; PF04151 PPC [H]

EC number: NA

Molecular weight: Translated: 89819; Mature: 89819

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00136 SUBTILASE_ASP ; PS00137 SUBTILASE_HIS ; PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGCRPFRFFRGVARMRRLLLMGLLLLSVTSCSGDDEDPGEQSSRTGRIQGTLTPFRSSE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCCC
RSAGDGASQTVRSPFRAGELEKLKETLRGMHAGRSREPRVAPKAMPGLPIIPSQPAAAPL
CCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
ERASREDPTIPGDVILRFEEAGLTPERVLAAVQRPGFRAVHKGYASEYVHLVGYEPLDGK
HHCCCCCCCCCHHEEEEEHHCCCCHHHHHHHHHCCCHHHHHHHHHHCEEEEEECCCCCCC
AVTAAKTQEWAAQLAQVPGVTYAVRNERMRATAAPNDRGYSLQWHYPTLNLPAAWDLVPD
EEEHHHHHHHHHHHHHCCCCEEEECCCCEEEECCCCCCCEEEEEECCCCCCCCCEECCCC
ASSVVVAVLDSGIVPHPDLTNVLPGYDMISDPENAGDGDGRDSNPRDEGGDTPSGGSTWH
CHHEEEEEECCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GSHVAGTIAADTNNQVGVAGVAWNARLLPVRVLGKKGGSSFDIAAAITWATGGPVPGVPP
CCCEEEEEEECCCCCEEEEEEEECCEEEEEEEECCCCCCCEEEEEEEEECCCCCCCCCCC
NPNPAKVVNMSLGGRAPPQALYQDAIDAALGRGAIIVVAAGNEDVDARTSTPCNQQNVVC
CCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCEEE
VGSTSLAGQRSSFSNYGVDVDVVASGGEMREDLNGDGYPDGVLSTVLDENGQPAYAFSQG
EECCCCCCCCCCCCCCCCEEEEEECCCHHHHHCCCCCCCHHHHHHHHCCCCCCEEEECCC
TSMAAPHVTGVVALMAASRPDLTAALAERILKETATPLTNAQCPEGCGAGLVNARAALAR
CCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHH
IANVDPGTLDPQLNVTTSTLFFRGSGTQPLILSNVGGNRGGDLTVSASVSGPNASAVSFP
HHCCCCCCCCCCCEEEEEEEEEECCCCCCEEEECCCCCCCCCEEEEEECCCCCCCEEECC
QGNTVRVPAFSSAPLSVAVDASGLAGGDTVVTLSLVGSGTAGSATVAVKIGVAGAANDLD
CCCEEEECCCCCCCEEEEEECCCCCCCCEEEEEEEECCCCCCCEEEEEEEECCCCCCHHH
ALIAFVWQDARGEWQASKDAIAVARASADYAYSISLAPRTYFALATIDDDQDGNFFEDGE
HHHHHHHHCCCCCCCCCCCEEEEEECCCCEEEEEEECCCEEEEEEEECCCCCCCCCCCCC
RTGYWRNVDSFEPLELEAGDRIENVSFDLIPLAPIDDDPALVVGSACGSNVDCPGGVCVT
CCCCCCCCCCCCCEEECCCCCCCCCEEEEEEECCCCCCCCEEEECCCCCCCCCCCCEEEE
DYPGGYCSMDCTSSACPAGSRCYIVDSSSGLKACLATCTRQVGTGQGDCRPGYVCYSDGT
CCCCCEEECCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCEEEEECCC
GSGACQPNCRTSGLTCGLGRTCTASGFCR
CCCCCCCCCCCCCEEECCCCCCCCCCCCC
>Mature Secondary Structure
MLGCRPFRFFRGVARMRRLLLMGLLLLSVTSCSGDDEDPGEQSSRTGRIQGTLTPFRSSE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCCC
RSAGDGASQTVRSPFRAGELEKLKETLRGMHAGRSREPRVAPKAMPGLPIIPSQPAAAPL
CCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
ERASREDPTIPGDVILRFEEAGLTPERVLAAVQRPGFRAVHKGYASEYVHLVGYEPLDGK
HHCCCCCCCCCHHEEEEEHHCCCCHHHHHHHHHCCCHHHHHHHHHHCEEEEEECCCCCCC
AVTAAKTQEWAAQLAQVPGVTYAVRNERMRATAAPNDRGYSLQWHYPTLNLPAAWDLVPD
EEEHHHHHHHHHHHHHCCCCEEEECCCCEEEECCCCCCCEEEEEECCCCCCCCCEECCCC
ASSVVVAVLDSGIVPHPDLTNVLPGYDMISDPENAGDGDGRDSNPRDEGGDTPSGGSTWH
CHHEEEEEECCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GSHVAGTIAADTNNQVGVAGVAWNARLLPVRVLGKKGGSSFDIAAAITWATGGPVPGVPP
CCCEEEEEEECCCCCEEEEEEEECCEEEEEEEECCCCCCCEEEEEEEEECCCCCCCCCCC
NPNPAKVVNMSLGGRAPPQALYQDAIDAALGRGAIIVVAAGNEDVDARTSTPCNQQNVVC
CCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCEEE
VGSTSLAGQRSSFSNYGVDVDVVASGGEMREDLNGDGYPDGVLSTVLDENGQPAYAFSQG
EECCCCCCCCCCCCCCCCEEEEEECCCHHHHHCCCCCCCHHHHHHHHCCCCCCEEEECCC
TSMAAPHVTGVVALMAASRPDLTAALAERILKETATPLTNAQCPEGCGAGLVNARAALAR
CCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHH
IANVDPGTLDPQLNVTTSTLFFRGSGTQPLILSNVGGNRGGDLTVSASVSGPNASAVSFP
HHCCCCCCCCCCCEEEEEEEEEECCCCCCEEEECCCCCCCCCEEEEEECCCCCCCEEECC
QGNTVRVPAFSSAPLSVAVDASGLAGGDTVVTLSLVGSGTAGSATVAVKIGVAGAANDLD
CCCEEEECCCCCCCEEEEEECCCCCCCCEEEEEEEECCCCCCCEEEEEEEECCCCCCHHH
ALIAFVWQDARGEWQASKDAIAVARASADYAYSISLAPRTYFALATIDDDQDGNFFEDGE
HHHHHHHHCCCCCCCCCCCEEEEEECCCCEEEEEEECCCEEEEEEEECCCCCCCCCCCCC
RTGYWRNVDSFEPLELEAGDRIENVSFDLIPLAPIDDDPALVVGSACGSNVDCPGGVCVT
CCCCCCCCCCCCCEEECCCCCCCCCEEEEEEECCCCCCCCEEEECCCCCCCCCCCCEEEE
DYPGGYCSMDCTSSACPAGSRCYIVDSSSGLKACLATCTRQVGTGQGDCRPGYVCYSDGT
CCCCCEEECCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCEEEEECCC
GSGACQPNCRTSGLTCGLGRTCTASGFCR
CCCCCCCCCCCCCEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2187155; 12024217 [H]