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The map label for this gene is hly [H]

Identifier: 108762694

GI number: 108762694

Start: 751212

End: 753047

Strand: Direct

Name: hly [H]

Synonym: MXAN_0653

Alternate gene names: 108762694

Gene position: 751212-753047 (Clockwise)

Preceding gene: 108761806

Following gene: 108759191

Centisome position: 8.22

GC content: 68.74

Gene sequence:

>1836_bases
GTGGCGGTGACCGTCCTTGGCATTCCTGACCTCCCGTCCTCTCTCCTGGCGCCGTCCCTGGGGCGTCGGGCCGCGTCGCG
GCATGTAGCATGTCGGCCGGGGGAGGCGCTGACGCCGCCTCGGGCTGATCGCTGGAAACTTTGTCCGACACAATGCGACA
ATCATTTATCGGCGTTTTTTTCTGCCCCCCACGGAGCTCCCCCCACCATGGAAATCTCTCGCAAGCCGAAGTCGCCCGTG
TCGCAGTCCACTCGCGCTGGTGACACGGCCAAGCCGGCCGCTGCGGCCAGGCCCGTGGAGAAGGCGCCGGTCCAGACGGC
GAAGGATGGCTTCGACTCGGCGCCCACGGGTGGCGCGCGGGGCTCCAACTTCGTGGACCGCCCGAAGGGCAACTTCGTGG
ACCGCCCCACGGGCCTGCCCCAGGGCACCCCGTCGGCGCTGCCGGCCTCGGCCTTCACCTTCGGCTCCGGCCACGTCGCC
GTCCGTCCCTTCGCGGCGAGCGCGGCCCGCGCGCCCGTGACGCTGACGGCGTCCGCCACGCCCAGCGCGAAGGTGAACGA
CCTCCAGACGACGACGTCCACCGTGTCCTTCGACCAGGACGTGAAGCTGGACTCGCTGAAGCTGAACCTGGATCTGGCGC
ACACCTTCAAGGGTGACCTGGTCGTCAAGCTGACCAGCCCCTCCGGCAAGACGGAGACGCTCCACAACCGCAAGGGCGGC
AGCGCGGACAACATCAAGGGCAGCTTCGACCTGGCCGCCTTCAAGGGCGAGTCCACCAAGGGCACCTGGACGCTCTCGGT
CGAGGACAAGGCGCGCCGCGACACGGGCACCCTGAAGAGCTGGAGCCTGGACGCCGCCGGCCAGACGACGGGCACGGGCC
CCATCGAGGAGCCGAAGCCCCAGCTCTCCGGCCCGCCGGTCATCGCCGTGTTCGACGGCGGCGTGGACTTCAAGCACTCC
GACCTGGATGACGCGATGTGGGTCAACCCGAACGAGGTCGCGGGTGACGGCATCGACAACGACGGCAACGGCGTCAAGGA
CGACATCTACGGCTACAACGTCGGCTACAACAGCGGCGACGTGATGCGCGGCAGCGGCACGGACCACGGCACGCACGTGG
CCGGCATCATCGCCGCCGAGGACAACGGCGAGGGCAACACCGGCGTCGCCGCGGGCAAGGCGAAGATCATGAGCCTGGGT
GGCCTGTACAACGGCGCGGACCTGCTCACGAACTTCGAGCGCGGCGTCGACTACATGGTGAAGATGAAGACCGAGCACGG
CGTGAACATCCGCGCCGTCAACGCGAGCTTCGGCAACGAGTACCGTGACGCGGCCTCCGTGAAGCGCTGGACGGACGCGG
TGCAGAAGCTGGCTGACGCGGACATCCTCCTCGTCGCGGCCACGGCGAACGGCTACGGCAGCAACCTGAACGACGTGGCG
GACATGCCCGCCAACATCGACCTGCCCAACGTCATCACCGTGGCGTCCATGGACAAGAAGAACGACAAGCTCGCGGACTT
CTCCTCCTACGGGGACAAGGTCGTGGAGCTGGCCGCGGTGGGTGAGGACGTGCTGAGCACCGTCCCGGGCGGCGGCTGGG
AGGAGATGAGCGGCACCTCCATGGCCACCCCGACGGTGGCGGGCGCCGCGGCGCTGATGTTCGCCGAAAACCCCAATCTG
ACGGCCGCGCAGGTGCGTGACCTGCTGGTCCAGACGGTGGAGGTGGACTCCGACCTCAAGGGCAAGGTGAGCACCAGCGG
CAAGCTGGACATCGAGGCCGCCGTCGCCGCCGCCAAGGCCACGCTCGAGGACGACACCGCGGTCGCCGGGCGCTGA

Upstream 100 bases:

>100_bases
CTGTCCGGCGCCCCGGAACTTCACGACGTAGAGCCCTGCGTCGTCCGCCTCGATGATGGCCGGCAGCGAGCCGCCCTCCC
GCAGTGGCGTCACGTAGCGC

Downstream 100 bases:

>100_bases
GCCGGACCTGAGGTGACGCAGTGAAGAACTCCCGGTGCCCAGGTGCCGGGAGTTTTTTCGTGCCCGATTTGATTGCGCAC
AATTTAATTGCGTCCTATTT

Product: S8A family peptidase

Products: NA

Alternate protein names: F-II [H]

Number of amino acids: Translated: 611; Mature: 610

Protein sequence:

>611_residues
MAVTVLGIPDLPSSLLAPSLGRRAASRHVACRPGEALTPPRADRWKLCPTQCDNHLSAFFSAPHGAPPTMEISRKPKSPV
SQSTRAGDTAKPAAAARPVEKAPVQTAKDGFDSAPTGGARGSNFVDRPKGNFVDRPTGLPQGTPSALPASAFTFGSGHVA
VRPFAASAARAPVTLTASATPSAKVNDLQTTTSTVSFDQDVKLDSLKLNLDLAHTFKGDLVVKLTSPSGKTETLHNRKGG
SADNIKGSFDLAAFKGESTKGTWTLSVEDKARRDTGTLKSWSLDAAGQTTGTGPIEEPKPQLSGPPVIAVFDGGVDFKHS
DLDDAMWVNPNEVAGDGIDNDGNGVKDDIYGYNVGYNSGDVMRGSGTDHGTHVAGIIAAEDNGEGNTGVAAGKAKIMSLG
GLYNGADLLTNFERGVDYMVKMKTEHGVNIRAVNASFGNEYRDAASVKRWTDAVQKLADADILLVAATANGYGSNLNDVA
DMPANIDLPNVITVASMDKKNDKLADFSSYGDKVVELAAVGEDVLSTVPGGGWEEMSGTSMATPTVAGAAALMFAENPNL
TAAQVRDLLVQTVEVDSDLKGKVSTSGKLDIEAAVAAAKATLEDDTAVAGR

Sequences:

>Translated_611_residues
MAVTVLGIPDLPSSLLAPSLGRRAASRHVACRPGEALTPPRADRWKLCPTQCDNHLSAFFSAPHGAPPTMEISRKPKSPV
SQSTRAGDTAKPAAAARPVEKAPVQTAKDGFDSAPTGGARGSNFVDRPKGNFVDRPTGLPQGTPSALPASAFTFGSGHVA
VRPFAASAARAPVTLTASATPSAKVNDLQTTTSTVSFDQDVKLDSLKLNLDLAHTFKGDLVVKLTSPSGKTETLHNRKGG
SADNIKGSFDLAAFKGESTKGTWTLSVEDKARRDTGTLKSWSLDAAGQTTGTGPIEEPKPQLSGPPVIAVFDGGVDFKHS
DLDDAMWVNPNEVAGDGIDNDGNGVKDDIYGYNVGYNSGDVMRGSGTDHGTHVAGIIAAEDNGEGNTGVAAGKAKIMSLG
GLYNGADLLTNFERGVDYMVKMKTEHGVNIRAVNASFGNEYRDAASVKRWTDAVQKLADADILLVAATANGYGSNLNDVA
DMPANIDLPNVITVASMDKKNDKLADFSSYGDKVVELAAVGEDVLSTVPGGGWEEMSGTSMATPTVAGAAALMFAENPNL
TAAQVRDLLVQTVEVDSDLKGKVSTSGKLDIEAAVAAAKATLEDDTAVAGR
>Mature_610_residues
AVTVLGIPDLPSSLLAPSLGRRAASRHVACRPGEALTPPRADRWKLCPTQCDNHLSAFFSAPHGAPPTMEISRKPKSPVS
QSTRAGDTAKPAAAARPVEKAPVQTAKDGFDSAPTGGARGSNFVDRPKGNFVDRPTGLPQGTPSALPASAFTFGSGHVAV
RPFAASAARAPVTLTASATPSAKVNDLQTTTSTVSFDQDVKLDSLKLNLDLAHTFKGDLVVKLTSPSGKTETLHNRKGGS
ADNIKGSFDLAAFKGESTKGTWTLSVEDKARRDTGTLKSWSLDAAGQTTGTGPIEEPKPQLSGPPVIAVFDGGVDFKHSD
LDDAMWVNPNEVAGDGIDNDGNGVKDDIYGYNVGYNSGDVMRGSGTDHGTHVAGIIAAEDNGEGNTGVAAGKAKIMSLGG
LYNGADLLTNFERGVDYMVKMKTEHGVNIRAVNASFGNEYRDAASVKRWTDAVQKLADADILLVAATANGYGSNLNDVAD
MPANIDLPNVITVASMDKKNDKLADFSSYGDKVVELAAVGEDVLSTVPGGGWEEMSGTSMATPTVAGAAALMFAENPNLT
AAQVRDLLVQTVEVDSDLKGKVSTSGKLDIEAAVAAAKATLEDDTAVAGR

Specific function: Unknown

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500
- InterPro:   IPR006311 [H]

Pfam domain/function: PF00082 Peptidase_S8 [H]

EC number: NA

Molecular weight: Translated: 63375; Mature: 63244

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS00137 SUBTILASE_HIS ; PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVTVLGIPDLPSSLLAPSLGRRAASRHVACRPGEALTPPRADRWKLCPTQCDNHLSAFF
CEEEEEECCCCCHHHHCCHHHHHHHHCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHH
SAPHGAPPTMEISRKPKSPVSQSTRAGDTAKPAAAARPVEKAPVQTAKDGFDSAPTGGAR
CCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCHHHCCCCHHCCCHHHHCCCCCCCCCCCC
GSNFVDRPKGNFVDRPTGLPQGTPSALPASAFTFGSGHVAVRPFAASAARAPVTLTASAT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEECCCCCCCCCEEEEECCC
PSAKVNDLQTTTSTVSFDQDVKLDSLKLNLDLAHTFKGDLVVKLTSPSGKTETLHNRKGG
CCCCCCCCCCCCEEECCCCCCEEEEEEEEEEEEEECCCCEEEEEECCCCCCCHHHCCCCC
SADNIKGSFDLAAFKGESTKGTWTLSVEDKARRDTGTLKSWSLDAAGQTTGTGPIEEPKP
CCCCCCCCEEEEEEECCCCCCEEEEEECCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCC
QLSGPPVIAVFDGGVDFKHSDLDDAMWVNPNEVAGDGIDNDGNGVKDDIYGYNVGYNSGD
CCCCCCEEEEECCCCCCCCCCCCCCEECCCHHHCCCCCCCCCCCCCCCCCEEECCCCCCC
VMRGSGTDHGTHVAGIIAAEDNGEGNTGVAAGKAKIMSLGGLYNGADLLTNFERGVDYMV
EEECCCCCCCCEEEEEEEECCCCCCCCCEECCCEEEEEECCCCCCHHHHHHHHHCCEEEE
KMKTEHGVNIRAVNASFGNEYRDAASVKRWTDAVQKLADADILLVAATANGYGSNLNDVA
EEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHH
DMPANIDLPNVITVASMDKKNDKLADFSSYGDKVVELAAVGEDVLSTVPGGGWEEMSGTS
CCCCCCCCCCEEEEEECCCCCCCHHHHHHHCHHHHHHHHHCHHHHHHCCCCCHHHCCCCC
MATPTVAGAAALMFAENPNLTAAQVRDLLVQTVEVDSDLKGKVSTSGKLDIEAAVAAAKA
CCCCHHHCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEHHHHHHHHHH
TLEDDTAVAGR
HCCCCCCCCCC
>Mature Secondary Structure 
AVTVLGIPDLPSSLLAPSLGRRAASRHVACRPGEALTPPRADRWKLCPTQCDNHLSAFF
EEEEEECCCCCHHHHCCHHHHHHHHCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHH
SAPHGAPPTMEISRKPKSPVSQSTRAGDTAKPAAAARPVEKAPVQTAKDGFDSAPTGGAR
CCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCHHHCCCCHHCCCHHHHCCCCCCCCCCCC
GSNFVDRPKGNFVDRPTGLPQGTPSALPASAFTFGSGHVAVRPFAASAARAPVTLTASAT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEECCCCCCCCCEEEEECCC
PSAKVNDLQTTTSTVSFDQDVKLDSLKLNLDLAHTFKGDLVVKLTSPSGKTETLHNRKGG
CCCCCCCCCCCCEEECCCCCCEEEEEEEEEEEEEECCCCEEEEEECCCCCCCHHHCCCCC
SADNIKGSFDLAAFKGESTKGTWTLSVEDKARRDTGTLKSWSLDAAGQTTGTGPIEEPKP
CCCCCCCCEEEEEEECCCCCCEEEEEECCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCC
QLSGPPVIAVFDGGVDFKHSDLDDAMWVNPNEVAGDGIDNDGNGVKDDIYGYNVGYNSGD
CCCCCCEEEEECCCCCCCCCCCCCCEECCCHHHCCCCCCCCCCCCCCCCCEEECCCCCCC
VMRGSGTDHGTHVAGIIAAEDNGEGNTGVAAGKAKIMSLGGLYNGADLLTNFERGVDYMV
EEECCCCCCCCEEEEEEEECCCCCCCCCEECCCEEEEEECCCCCCHHHHHHHHHCCEEEE
KMKTEHGVNIRAVNASFGNEYRDAASVKRWTDAVQKLADADILLVAATANGYGSNLNDVA
EEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHH
DMPANIDLPNVITVASMDKKNDKLADFSSYGDKVVELAAVGEDVLSTVPGGGWEEMSGTS
CCCCCCCCCCEEEEEECCCCCCCHHHHHHHCHHHHHHHHHCHHHHHHCCCCCHHHCCCCC
MATPTVAGAAALMFAENPNLTAAQVRDLLVQTVEVDSDLKGKVSTSGKLDIEAAVAAAKA
CCCCHHHCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEHHHHHHHHHH
TLEDDTAVAGR
HCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1732209; 2112401 [H]