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The map label for this gene is trx [H]

Identifier: 108762690

GI number: 108762690

Start: 3095262

End: 3095594

Strand: Reverse

Name: trx [H]

Synonym: MXAN_2652

Alternate gene names: 108762690

Gene position: 3095594-3095262 (Counterclockwise)

Preceding gene: 108762594

Following gene: 108757073

Centisome position: 33.87

GC content: 65.17

Gene sequence:

>333_bases
ATGGCAGGCGCGGACGTGACGAACATCGGGGATGGCGATTTCAAGCAGCAGGTCCTGGACTCCCAGGAGCCCGTGCTGGT
GGATTTCTGGGCGACGTGGTGCGCGCCGTGCCGCGCCATCGCGCCCTCCATCGAAGCGCTGGCCTCGCAGTACAAGGGGC
AGGTGAAGTTCGCCAAGCTCAACATCGATGAGAACCAGGACACGCCGCAGGAGTACGGCATCCGTTCCATCCCCACCCTG
CTCCTGTTCAAGGGCGGCCGCGTGGTGGAGCAGATTGTCGGCGCGGTGCCCAAGGCCCGCATCGAAGAGGCGGTGAAGAA
GGCCCTGACGTAG

Upstream 100 bases:

>100_bases
CTGAGCCGCCAGATTGGCTGATGGCCGGCCGATCCTTGCAGGCCCACCGGACGCGTACTACACGCGGCGGAGGTGCCCGG
ACAGGGCACGAGGAGACACC

Downstream 100 bases:

>100_bases
ACGCGCCGCGCTGCGGGGTCGGACGCGCGAGAGAGCCCCTGCTGCTCTTCCGCGCCCCTCCCCGCGGCCTCCTCCTGTCT
CAGCCCAGCAACTCCACGCA

Product: thioredoxin

Products: NA

Alternate protein names: Trx [H]

Number of amino acids: Translated: 110; Mature: 109

Protein sequence:

>110_residues
MAGADVTNIGDGDFKQQVLDSQEPVLVDFWATWCAPCRAIAPSIEALASQYKGQVKFAKLNIDENQDTPQEYGIRSIPTL
LLFKGGRVVEQIVGAVPKARIEEAVKKALT

Sequences:

>Translated_110_residues
MAGADVTNIGDGDFKQQVLDSQEPVLVDFWATWCAPCRAIAPSIEALASQYKGQVKFAKLNIDENQDTPQEYGIRSIPTL
LLFKGGRVVEQIVGAVPKARIEEAVKKALT
>Mature_109_residues
AGADVTNIGDGDFKQQVLDSQEPVLVDFWATWCAPCRAIAPSIEALASQYKGQVKFAKLNIDENQDTPQEYGIRSIPTLL
LFKGGRVVEQIVGAVPKARIEEAVKKALT

Specific function: Component of the thioredoxin-thioredoxin reductase system. Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI21361403, Length=103, Percent_Identity=39.8058252427184, Blast_Score=90, Evalue=4e-19,
Organism=Homo sapiens, GI21361657, Length=126, Percent_Identity=31.7460317460317, Blast_Score=67, Evalue=3e-12,
Organism=Homo sapiens, GI5031973, Length=86, Percent_Identity=39.5348837209302, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI87082331, Length=104, Percent_Identity=46.1538461538462, Blast_Score=106, Evalue=3e-25,
Organism=Escherichia coli, GI1788936, Length=98, Percent_Identity=41.8367346938776, Blast_Score=97, Evalue=2e-22,
Organism=Escherichia coli, GI87081747, Length=111, Percent_Identity=36.036036036036, Blast_Score=74, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17510299, Length=98, Percent_Identity=45.9183673469388, Blast_Score=85, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI212646193, Length=108, Percent_Identity=34.2592592592593, Blast_Score=81, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI71980565, Length=86, Percent_Identity=38.3720930232558, Blast_Score=76, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI71980562, Length=86, Percent_Identity=38.3720930232558, Blast_Score=75, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI71998175, Length=87, Percent_Identity=42.5287356321839, Blast_Score=73, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17509965, Length=100, Percent_Identity=38, Blast_Score=73, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17507705, Length=91, Percent_Identity=34.0659340659341, Blast_Score=68, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI115532378, Length=81, Percent_Identity=39.5061728395062, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17556044, Length=81, Percent_Identity=35.8024691358025, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17544108, Length=82, Percent_Identity=39.0243902439024, Blast_Score=65, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI115532380, Length=82, Percent_Identity=39.0243902439024, Blast_Score=65, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6321648, Length=81, Percent_Identity=49.3827160493827, Blast_Score=84, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6323072, Length=81, Percent_Identity=50.6172839506173, Blast_Score=84, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6319925, Length=91, Percent_Identity=32.967032967033, Blast_Score=70, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28573567, Length=97, Percent_Identity=38.1443298969072, Blast_Score=92, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24639826, Length=90, Percent_Identity=44.4444444444444, Blast_Score=89, Evalue=5e-19,
Organism=Drosophila melanogaster, GI17648013, Length=86, Percent_Identity=40.6976744186046, Blast_Score=79, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24583090, Length=86, Percent_Identity=40.6976744186046, Blast_Score=79, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24664269, Length=75, Percent_Identity=42.6666666666667, Blast_Score=75, Evalue=6e-15,
Organism=Drosophila melanogaster, GI21358065, Length=82, Percent_Identity=40.2439024390244, Blast_Score=75, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24639068, Length=93, Percent_Identity=30.1075268817204, Blast_Score=69, Evalue=5e-13,
Organism=Drosophila melanogaster, GI19921434, Length=82, Percent_Identity=35.3658536585366, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00085 Thioredoxin [H]

EC number: NA

Molecular weight: Translated: 11989; Mature: 11858

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGADVTNIGDGDFKQQVLDSQEPVLVDFWATWCAPCRAIAPSIEALASQYKGQVKFAKL
CCCCCCCCCCCCHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
NIDENQDTPQEYGIRSIPTLLLFKGGRVVEQIVGAVPKARIEEAVKKALT
ECCCCCCCHHHCCCHHCCHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
AGADVTNIGDGDFKQQVLDSQEPVLVDFWATWCAPCRAIAPSIEALASQYKGQVKFAKL
CCCCCCCCCCCHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
NIDENQDTPQEYGIRSIPTLLLFKGGRVVEQIVGAVPKARIEEAVKKALT
ECCCCCCCHHHCCCHHCCHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Reduction reactions; participates in dithiol-disulfide exchange reactions [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8756494; 8590279; 8905231; 9298645 [H]