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The map label for this gene is htpX [H]

Identifier: 108762681

GI number: 108762681

Start: 6284908

End: 6285810

Strand: Direct

Name: htpX [H]

Synonym: MXAN_5027

Alternate gene names: 108762681

Gene position: 6284908-6285810 (Clockwise)

Preceding gene: 108758641

Following gene: 108756841

Centisome position: 68.76

GC content: 71.43

Gene sequence:

>903_bases
TTGGGCAATACGCTCAAGACGACCGTGCTGCTGGCCGGGCTCACGGCCCTGGTGCTCGTCATCGGCGACCGGCTGGGCGG
CCCGCAAGGCCTGCTCTTCGCCGGCCTTTTCGCGGTGGTGATGAACTTCGGCTCCTACTGGTTCAGCGACCGGATTGCCT
TGGCCATCCACGGCGCCAGGCCGTTGCCCTACGAGCAGGCGCCCTGGCTGCACGACATGGTGGCGCGGCTGGCCTCCCGC
GCGGGCATGCCGAAGCCCAAGGTCTACATCCTCCCCACGGCGGCGCCCAACGCGTTCGCCACGGGCCGCAACCCGAGCCA
CGCCGCCATCGCGGTGACGGCGGGCCTGATGGAGCTGCTCGACCGGCGCGAGCTGGAAGGCGTGCTGGCCCATGAACTGG
GGCACGTTCGCAACCGGGACACCCTCATCGGCACGGTGGCGGCGACCCTGGCCGGCATCATCAGCTACGCCGCGCAGATG
CTCTTCTGGTTCGGCGGCTCCATGCTCAGCCGGGGCGACAACGACGAGCGCGGCGGACTGGGCAGCGCCTTCGCCAACCT
GGGTCTGCTGCTGGTGGCCCCCATCGCCGCCACGCTGCTCCAGCTCGCCGTCAGCCGCTCACGGGAGTACGGAGCGGACC
AGACGGGCGCCGAGCTGGCGGGCGACCCGGACGCGCTCGCCAATGCCCTGCTGAAGTTGGAACGCAGCGCGGAGGCCATT
CCCTACGACAAGGCCCCGGCCACCTCCCACCTCTTCATCGTCAACCCGCTCCACCGAGGCGGAGTCATGGCCCTGTTCTC
CACCCACCCGCCCATCCCCGAGCGGGTCCGCCGGCTGCGGGAGCTGGGCGCCCGCCTGGGAGCCCGCACCGGTGGGCGCG
GCGGCTGGGAGTACGCGTACTGA

Upstream 100 bases:

>100_bases
CTCCGGAAACGAGGCGGCCATGGCGCTCAATTCTTCCCACGATACGGCCCGCGCCGGCGCGGACCGGCCAGCACTGCACG
GCGGAGGCGGTTGGCACCGG

Downstream 100 bases:

>100_bases
GGCGACGGACGGCGCCCCGGACGCTCGCCGGGCCGCTGGCCGGGGCGACGCAGGGAGTGAACCGAAGCACGTCTAGCAGT
GGACCCTTGACGCCCCGGGG

Product: M48B family peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MGNTLKTTVLLAGLTALVLVIGDRLGGPQGLLFAGLFAVVMNFGSYWFSDRIALAIHGARPLPYEQAPWLHDMVARLASR
AGMPKPKVYILPTAAPNAFATGRNPSHAAIAVTAGLMELLDRRELEGVLAHELGHVRNRDTLIGTVAATLAGIISYAAQM
LFWFGGSMLSRGDNDERGGLGSAFANLGLLLVAPIAATLLQLAVSRSREYGADQTGAELAGDPDALANALLKLERSAEAI
PYDKAPATSHLFIVNPLHRGGVMALFSTHPPIPERVRRLRELGARLGARTGGRGGWEYAY

Sequences:

>Translated_300_residues
MGNTLKTTVLLAGLTALVLVIGDRLGGPQGLLFAGLFAVVMNFGSYWFSDRIALAIHGARPLPYEQAPWLHDMVARLASR
AGMPKPKVYILPTAAPNAFATGRNPSHAAIAVTAGLMELLDRRELEGVLAHELGHVRNRDTLIGTVAATLAGIISYAAQM
LFWFGGSMLSRGDNDERGGLGSAFANLGLLLVAPIAATLLQLAVSRSREYGADQTGAELAGDPDALANALLKLERSAEAI
PYDKAPATSHLFIVNPLHRGGVMALFSTHPPIPERVRRLRELGARLGARTGGRGGWEYAY
>Mature_299_residues
GNTLKTTVLLAGLTALVLVIGDRLGGPQGLLFAGLFAVVMNFGSYWFSDRIALAIHGARPLPYEQAPWLHDMVARLASRA
GMPKPKVYILPTAAPNAFATGRNPSHAAIAVTAGLMELLDRRELEGVLAHELGHVRNRDTLIGTVAATLAGIISYAAQML
FWFGGSMLSRGDNDERGGLGSAFANLGLLLVAPIAATLLQLAVSRSREYGADQTGAELAGDPDALANALLKLERSAEAIP
YDKAPATSHLFIVNPLHRGGVMALFSTHPPIPERVRRLRELGARLGARTGGRGGWEYAY

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=271, Percent_Identity=33.5793357933579, Blast_Score=95, Evalue=7e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.-

Molecular weight: Translated: 31893; Mature: 31762

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNTLKTTVLLAGLTALVLVIGDRLGGPQGLLFAGLFAVVMNFGSYWFSDRIALAIHGAR
CCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCC
PLPYEQAPWLHDMVARLASRAGMPKPKVYILPTAAPNAFATGRNPSHAAIAVTAGLMELL
CCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHH
DRRELEGVLAHELGHVRNRDTLIGTVAATLAGIISYAAQMLFWFGGSMLSRGDNDERGGL
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCH
GSAFANLGLLLVAPIAATLLQLAVSRSREYGADQTGAELAGDPDALANALLKLERSAEAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCC
PYDKAPATSHLFIVNPLHRGGVMALFSTHPPIPERVRRLRELGARLGARTGGRGGWEYAY
CCCCCCCCCEEEEECCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
GNTLKTTVLLAGLTALVLVIGDRLGGPQGLLFAGLFAVVMNFGSYWFSDRIALAIHGAR
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCC
PLPYEQAPWLHDMVARLASRAGMPKPKVYILPTAAPNAFATGRNPSHAAIAVTAGLMELL
CCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHH
DRRELEGVLAHELGHVRNRDTLIGTVAATLAGIISYAAQMLFWFGGSMLSRGDNDERGGL
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCH
GSAFANLGLLLVAPIAATLLQLAVSRSREYGADQTGAELAGDPDALANALLKLERSAEAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCC
PYDKAPATSHLFIVNPLHRGGVMALFSTHPPIPERVRRLRELGARLGARTGGRGGWEYAY
CCCCCCCCCEEEEECCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA