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The map label for this gene is yrpG [H]

Identifier: 108762549

GI number: 108762549

Start: 775170

End: 776141

Strand: Reverse

Name: yrpG [H]

Synonym: MXAN_0678

Alternate gene names: 108762549

Gene position: 776141-775170 (Counterclockwise)

Preceding gene: 108761152

Following gene: 108762953

Centisome position: 8.49

GC content: 67.9

Gene sequence:

>972_bases
ATGAAGTACACGCAATTGGGCCGCTCGGGGCTCTCCGTCAGCCGGCTGTGCCTGGGCACCATGAACTTCGGTTGGACGGC
CGAGGAGCCGGAGTCCCACGCCATCATGGATTCCGCGCTCGGCCACGGCATCAACTTCTTCGACACCGCCAACGTCTACG
GCTTCGGGGAGAACAAGGGCCGCACCGAGGAGGTCATCGGCAACTGGTTCGCCAAGGGCGACCGGCGGCGCGAGCGCACC
GTGCTCGCGACCAAGCTCTACGCGCCCATGGGTGACTGGCCCAACGAGGGCAAGCTGTCCGCGCTCAACATCCGCCGCGC
GCTGGATGCCAGCTTGAAGCGGCTGCGCACGGACTACGTCGACCTCTATCAGTTCCACCACATCGACCGCGCCACGCCCT
GGGAGGAGATCTGGCAGGCCATGGAGGTGGCCGTGGCGCAGGGCAAGGTGCTCTACGTCGGCAGCAGCAACTTCGCGGGC
TGGCACATCGCCCAGGCCCAGGCCGTGGCGGCACGGCGCAACTTCACCGGACTGGTCAGCGAACAGTCGCTCTACAACCT
GATGGCGCGCACCGTGGAGCTGGAGGTGTTGCCCTCCGCGCAGTTCCATGGCGTGGGCATCCTCCCCTGGTCTCCCCTCC
AGGGCGGACTGCTGGGCGGCGTGCTCCGCAAGGAGCGCGAGGGCAAGCGCCGGCTGGAAGGACGCGCCAAGGAAGCCCTC
CAGAAGCACCGCGACCGCATCGAGCGCTACGAGGCGCTCGCCGACGAGCTCGGGCATGAGCCCGGTGACGTCGCGCTGGC
GTGGCTGCTGCACCAGCCCGCTGTCACCGCGCCCATCATCGGACCGCGAACCTCCGCCCAGCTCGATGCCGCCGTCCACG
CGGCCGGTGTCACACTTGATGCGAAAACATTGTCACGCCTGGATGACATCTTCCCGGGCCACAAGCCCGCCCCGGAGGAC
TACGCTTGGTGA

Upstream 100 bases:

>100_bases
ATGCGCCGCGGATGCCCTGAATGCACGGCACCCGCGGGACGGTGAACGGCCGGGCCGTCCTCGGTGGAGGGAGCCTGCCT
CCGGCCATCGAGGAGTCGCC

Downstream 100 bases:

>100_bases
CGCACCGGGCGAGACATAAAAGGCTACAAATCCCTCTCAATCGGTCGGAAAAGACACCCAAACATCACGGAGCGTCACTA
TTGACGACAGGAAATTCCTC

Product: aldo/keto reductase family oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MKYTQLGRSGLSVSRLCLGTMNFGWTAEEPESHAIMDSALGHGINFFDTANVYGFGENKGRTEEVIGNWFAKGDRRRERT
VLATKLYAPMGDWPNEGKLSALNIRRALDASLKRLRTDYVDLYQFHHIDRATPWEEIWQAMEVAVAQGKVLYVGSSNFAG
WHIAQAQAVAARRNFTGLVSEQSLYNLMARTVELEVLPSAQFHGVGILPWSPLQGGLLGGVLRKEREGKRRLEGRAKEAL
QKHRDRIERYEALADELGHEPGDVALAWLLHQPAVTAPIIGPRTSAQLDAAVHAAGVTLDAKTLSRLDDIFPGHKPAPED
YAW

Sequences:

>Translated_323_residues
MKYTQLGRSGLSVSRLCLGTMNFGWTAEEPESHAIMDSALGHGINFFDTANVYGFGENKGRTEEVIGNWFAKGDRRRERT
VLATKLYAPMGDWPNEGKLSALNIRRALDASLKRLRTDYVDLYQFHHIDRATPWEEIWQAMEVAVAQGKVLYVGSSNFAG
WHIAQAQAVAARRNFTGLVSEQSLYNLMARTVELEVLPSAQFHGVGILPWSPLQGGLLGGVLRKEREGKRRLEGRAKEAL
QKHRDRIERYEALADELGHEPGDVALAWLLHQPAVTAPIIGPRTSAQLDAAVHAAGVTLDAKTLSRLDDIFPGHKPAPED
YAW
>Mature_323_residues
MKYTQLGRSGLSVSRLCLGTMNFGWTAEEPESHAIMDSALGHGINFFDTANVYGFGENKGRTEEVIGNWFAKGDRRRERT
VLATKLYAPMGDWPNEGKLSALNIRRALDASLKRLRTDYVDLYQFHHIDRATPWEEIWQAMEVAVAQGKVLYVGSSNFAG
WHIAQAQAVAARRNFTGLVSEQSLYNLMARTVELEVLPSAQFHGVGILPWSPLQGGLLGGVLRKEREGKRRLEGRAKEAL
QKHRDRIERYEALADELGHEPGDVALAWLLHQPAVTAPIIGPRTSAQLDAAVHAAGVTLDAKTLSRLDDIFPGHKPAPED
YAW

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=336, Percent_Identity=33.3333333333333, Blast_Score=146, Evalue=2e-35,
Organism=Homo sapiens, GI4504825, Length=334, Percent_Identity=33.2335329341317, Blast_Score=145, Evalue=7e-35,
Organism=Homo sapiens, GI27436964, Length=335, Percent_Identity=32.5373134328358, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI27436962, Length=335, Percent_Identity=32.2388059701493, Blast_Score=141, Evalue=8e-34,
Organism=Homo sapiens, GI27436966, Length=335, Percent_Identity=31.9402985074627, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI27436971, Length=329, Percent_Identity=31.6109422492401, Blast_Score=131, Evalue=9e-31,
Organism=Homo sapiens, GI41152114, Length=218, Percent_Identity=30.2752293577982, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI223718702, Length=218, Percent_Identity=29.3577981651376, Blast_Score=95, Evalue=7e-20,
Organism=Homo sapiens, GI41327764, Length=219, Percent_Identity=31.5068493150685, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI223718708, Length=148, Percent_Identity=31.0810810810811, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI87081735, Length=328, Percent_Identity=39.6341463414634, Blast_Score=201, Evalue=6e-53,
Organism=Escherichia coli, GI1789199, Length=348, Percent_Identity=31.3218390804598, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1789375, Length=320, Percent_Identity=31.875, Blast_Score=120, Evalue=8e-29,
Organism=Escherichia coli, GI1788070, Length=324, Percent_Identity=27.7777777777778, Blast_Score=98, Evalue=9e-22,
Organism=Escherichia coli, GI1788081, Length=303, Percent_Identity=29.042904290429, Blast_Score=82, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6325169, Length=337, Percent_Identity=29.9703264094956, Blast_Score=150, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6323998, Length=336, Percent_Identity=27.9761904761905, Blast_Score=107, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6319958, Length=317, Percent_Identity=26.1829652996845, Blast_Score=105, Evalue=9e-24,
Organism=Saccharomyces cerevisiae, GI6319951, Length=346, Percent_Identity=25.4335260115607, Blast_Score=92, Evalue=9e-20,
Organism=Saccharomyces cerevisiae, GI6322615, Length=263, Percent_Identity=25.8555133079848, Blast_Score=87, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24640980, Length=327, Percent_Identity=28.1345565749235, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI45549126, Length=330, Percent_Identity=27.8787878787879, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24646155, Length=226, Percent_Identity=31.858407079646, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24646159, Length=227, Percent_Identity=29.9559471365639, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24644950, Length=162, Percent_Identity=30.2469135802469, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 35891; Mature: 35891

Theoretical pI: Translated: 7.43; Mature: 7.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYTQLGRSGLSVSRLCLGTMNFGWTAEEPESHAIMDSALGHGINFFDTANVYGFGENKG
CCCHHHCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCEECCCEEECCCCCC
RTEEVIGNWFAKGDRRRERTVLATKLYAPMGDWPNEGKLSALNIRRALDASLKRLRTDYV
CHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHH
DLYQFHHIDRATPWEEIWQAMEVAVAQGKVLYVGSSNFAGWHIAQAQAVAARRNFTGLVS
HHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCEEHHHHHHHHHHHCCHHHHH
EQSLYNLMARTVELEVLPSAQFHGVGILPWSPLQGGLLGGVLRKEREGKRRLEGRAKEAL
HHHHHHHHHHHHEEEEECCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QKHRDRIERYEALADELGHEPGDVALAWLLHQPAVTAPIIGPRTSAQLDAAVHAAGVTLD
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCEEC
AKTLSRLDDIFPGHKPAPEDYAW
HHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MKYTQLGRSGLSVSRLCLGTMNFGWTAEEPESHAIMDSALGHGINFFDTANVYGFGENKG
CCCHHHCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCEECCCEEECCCCCC
RTEEVIGNWFAKGDRRRERTVLATKLYAPMGDWPNEGKLSALNIRRALDASLKRLRTDYV
CHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHH
DLYQFHHIDRATPWEEIWQAMEVAVAQGKVLYVGSSNFAGWHIAQAQAVAARRNFTGLVS
HHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCEEHHHHHHHHHHHCCHHHHH
EQSLYNLMARTVELEVLPSAQFHGVGILPWSPLQGGLLGGVLRKEREGKRRLEGRAKEAL
HHHHHHHHHHHHEEEEECCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QKHRDRIERYEALADELGHEPGDVALAWLLHQPAVTAPIIGPRTSAQLDAAVHAAGVTLD
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCEEC
AKTLSRLDDIFPGHKPAPEDYAW
HHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9308178; 9384377 [H]