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The map label for this gene is ubiB [C]

Identifier: 108762347

GI number: 108762347

Start: 4689964

End: 4691655

Strand: Direct

Name: ubiB [C]

Synonym: MXAN_3899

Alternate gene names: 108762347

Gene position: 4689964-4691655 (Clockwise)

Preceding gene: 108763283

Following gene: 108761196

Centisome position: 51.31

GC content: 68.03

Gene sequence:

>1692_bases
GTGATTCTCCAAGACCTCAACCGCGTGCGGCAAATCACCGTCATCGCGGCACGCCACGGCTTTGGCGAGCTGGCGGAGCG
CGCGGGGCTGTGGCGCATCCTCGGCCGCAAGGAGAAGGTGGAAGTCTCTCCGGAGGCCCAGCGCGCCTCCACCGCGCGGC
GCTTCCGCATGCTGCTCAACGACCTGGGCCCCACCTTCGTCAAGCTGGGGCAGGTGCTGTCCACCCGCGCCGACCTGTTG
CCCGCCGAGTACATCGACGAGCTGGCCATGCTCCAGGACCACGTGGAGCCCATCTCCCTGGAGGATGTCCGCGCGCAGAT
TGAAGGTTCGCTCGGCGCCAGCGTGGAGAGCCTCTTCGCCACCATCGACTCGGCGCCGCTGGCCGCCGCGTCCATCGCCC
AGGTGCACCGCGCGCTGACGTTGGAGGGCGAAGAGGTGGTGGTGAAGGTGCAGCGGCCAGGCATCGCCGAGCGCATCGAC
TCCGACCTGGGCGTGCTGCGCAGCCTGGCGCGCCTGCTGGAGGCCGTGGTGGAGGAGACGGGCGTGTACACGCTCACCGG
CATCGTGGATGAGTTCGACCGGGCCATCCACGAGGAGTTGGACTTCATCAACGAGGCCACCAACATCCGGGCCTTCCTGG
AGAACCACCGCGAGCGGCCCTACCTCAAGATTCCGCGCGTCTACTCCGGCCTGTCCAGCCGCACGGTGCTGACCATGGAG
TTCATCCGCGGCGTGAAGCTCAACCCCGCGGAGCTGAGCGAGCCCGAGCGCAAGGCCATTGCCCAGAACATCCTGGACGC
CTCCTTCCGGCAGCTCTTCGAGGACGGCCTGTTCCACGGCGACCCGCACCCGGGCAACCTCCTGCTGCTGGAGGACCACC
GGCTGGCGCTGCTGGACTTCGGCGTGGTGGGCCGGCTGTCGCGCCCCATGCAGGAGACGCTGGTCATGCTGTGCCTGGCG
GTGGCGCTCAAGGACAGCGAATCCGTGGCGCGCATCCTCTACCGCGTGGGCGTGCCGGACGCGCGCGCCAACCTGGTGGG
CTTCCGCAACGACATCGAGGCGCTGCTCGGCCAGCACCTGACCACGACGCTGGGACAGGTGGACACGCGCTCGCTGCTGA
GGGACTTGCTGGACCTGGCGGTGAAGTACCGCATCCGCATCCCCAAGGAGTACGCGCTGCTCAGCCGGGCCTCCGTGTCC
ACGGAGGGCATGCTGCGCAGCCTGTACCCGGAGATGAACATCATCGAGGTGGCGCTGCCGTACGCCAAGGAGCTGCTCGC
CGGGCGCTACGATCCGATGCAGCTCCAGGGCGGGCTGATGCGCACGCTGCTGCGCTTCCAGGCCATGGCGCAGGACCTGC
CCACGCAGTTGTCGCAGATCCTGCTGGACATGGAGTCCGGCAAGTTCACCGTCACGGTGCGCGCGGACCAGTTCGAAAAG
CTGAATGAGAACCTGCGCAGTGCGGCGGTGATTGCCTTCATGGGCCTGTGCGCGTGCGGGTTCATCGTGGGCGCGTTCAT
CTCCTTCGCGCCCAAGCCGTGGATGTACGGCAACGTGCCGGTGCTCGGCGTGGTGGGCATCGCGGTGGCGGCGGCCTTCT
TCGGCGCGGCGATTACCTGGTACCTCTTCGGCGGCCGGGGCCTGGGCAAGGTGCGCTTGAGCCGCTTCCTCAAGAAGCCC
AAGCGCAAGTAG

Upstream 100 bases:

>100_bases
TTCTGGTGGGCTCGCTGCTTTCCGCGGTGGTGGGCTACGCACTCTTGCGCTTCGTGGCGAAACCGGCCGTCCCGGCGTAA
CGTAGAGGACAGGAACGCTC

Downstream 100 bases:

>100_bases
CCCGCCGCCTCTACACGGGCCGGCGCCACAGGTCGGCGAGGTCCGCCGGGAGCTGCGAGGCCACGGCCGCCACCTCGTCG
TCTGGAATCCGATCCCGGAT

Product: hypothetical protein

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 563; Mature: 563

Protein sequence:

>563_residues
MILQDLNRVRQITVIAARHGFGELAERAGLWRILGRKEKVEVSPEAQRASTARRFRMLLNDLGPTFVKLGQVLSTRADLL
PAEYIDELAMLQDHVEPISLEDVRAQIEGSLGASVESLFATIDSAPLAAASIAQVHRALTLEGEEVVVKVQRPGIAERID
SDLGVLRSLARLLEAVVEETGVYTLTGIVDEFDRAIHEELDFINEATNIRAFLENHRERPYLKIPRVYSGLSSRTVLTME
FIRGVKLNPAELSEPERKAIAQNILDASFRQLFEDGLFHGDPHPGNLLLLEDHRLALLDFGVVGRLSRPMQETLVMLCLA
VALKDSESVARILYRVGVPDARANLVGFRNDIEALLGQHLTTTLGQVDTRSLLRDLLDLAVKYRIRIPKEYALLSRASVS
TEGMLRSLYPEMNIIEVALPYAKELLAGRYDPMQLQGGLMRTLLRFQAMAQDLPTQLSQILLDMESGKFTVTVRADQFEK
LNENLRSAAVIAFMGLCACGFIVGAFISFAPKPWMYGNVPVLGVVGIAVAAAFFGAAITWYLFGGRGLGKVRLSRFLKKP
KRK

Sequences:

>Translated_563_residues
MILQDLNRVRQITVIAARHGFGELAERAGLWRILGRKEKVEVSPEAQRASTARRFRMLLNDLGPTFVKLGQVLSTRADLL
PAEYIDELAMLQDHVEPISLEDVRAQIEGSLGASVESLFATIDSAPLAAASIAQVHRALTLEGEEVVVKVQRPGIAERID
SDLGVLRSLARLLEAVVEETGVYTLTGIVDEFDRAIHEELDFINEATNIRAFLENHRERPYLKIPRVYSGLSSRTVLTME
FIRGVKLNPAELSEPERKAIAQNILDASFRQLFEDGLFHGDPHPGNLLLLEDHRLALLDFGVVGRLSRPMQETLVMLCLA
VALKDSESVARILYRVGVPDARANLVGFRNDIEALLGQHLTTTLGQVDTRSLLRDLLDLAVKYRIRIPKEYALLSRASVS
TEGMLRSLYPEMNIIEVALPYAKELLAGRYDPMQLQGGLMRTLLRFQAMAQDLPTQLSQILLDMESGKFTVTVRADQFEK
LNENLRSAAVIAFMGLCACGFIVGAFISFAPKPWMYGNVPVLGVVGIAVAAAFFGAAITWYLFGGRGLGKVRLSRFLKKP
KRK
>Mature_563_residues
MILQDLNRVRQITVIAARHGFGELAERAGLWRILGRKEKVEVSPEAQRASTARRFRMLLNDLGPTFVKLGQVLSTRADLL
PAEYIDELAMLQDHVEPISLEDVRAQIEGSLGASVESLFATIDSAPLAAASIAQVHRALTLEGEEVVVKVQRPGIAERID
SDLGVLRSLARLLEAVVEETGVYTLTGIVDEFDRAIHEELDFINEATNIRAFLENHRERPYLKIPRVYSGLSSRTVLTME
FIRGVKLNPAELSEPERKAIAQNILDASFRQLFEDGLFHGDPHPGNLLLLEDHRLALLDFGVVGRLSRPMQETLVMLCLA
VALKDSESVARILYRVGVPDARANLVGFRNDIEALLGQHLTTTLGQVDTRSLLRDLLDLAVKYRIRIPKEYALLSRASVS
TEGMLRSLYPEMNIIEVALPYAKELLAGRYDPMQLQGGLMRTLLRFQAMAQDLPTQLSQILLDMESGKFTVTVRADQFEK
LNENLRSAAVIAFMGLCACGFIVGAFISFAPKPWMYGNVPVLGVVGIAVAAAFFGAAITWYLFGGRGLGKVRLSRFLKKP
KRK

Specific function: Required, Probably Indirectly, For The Hydroxylation Of 2-Octaprenylphenol To 2-Octaprenyl-6-Hydroxy-Phenol, The Fourth Step In Ubiquinone Biosynthesis. Specific For Aerobically Grown Log-Phase Cells. [C]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. ADCK protein kinase family [H]

Homologues:

Organism=Homo sapiens, GI40254938, Length=314, Percent_Identity=29.2993630573248, Blast_Score=142, Evalue=7e-34,
Organism=Homo sapiens, GI41393593, Length=285, Percent_Identity=34.0350877192982, Blast_Score=131, Evalue=2e-30,
Organism=Homo sapiens, GI34147522, Length=331, Percent_Identity=29.9093655589124, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI217035081, Length=289, Percent_Identity=28.0276816608997, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI217416386, Length=310, Percent_Identity=30.3225806451613, Blast_Score=104, Evalue=3e-22,
Organism=Homo sapiens, GI27363457, Length=310, Percent_Identity=30.3225806451613, Blast_Score=104, Evalue=3e-22,
Organism=Escherichia coli, GI2367309, Length=504, Percent_Identity=28.1746031746032, Blast_Score=195, Evalue=7e-51,
Organism=Caenorhabditis elegans, GI17559152, Length=284, Percent_Identity=31.3380281690141, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI32565180, Length=247, Percent_Identity=30.7692307692308, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17555620, Length=476, Percent_Identity=21.6386554621849, Blast_Score=85, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6323282, Length=238, Percent_Identity=31.5126050420168, Blast_Score=119, Evalue=9e-28,
Organism=Saccharomyces cerevisiae, GI6321319, Length=256, Percent_Identity=30.078125, Blast_Score=101, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6325148, Length=436, Percent_Identity=22.4770642201835, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24662575, Length=291, Percent_Identity=29.553264604811, Blast_Score=140, Evalue=3e-33,
Organism=Drosophila melanogaster, GI22024280, Length=311, Percent_Identity=26.6881028938907, Blast_Score=119, Evalue=4e-27,
Organism=Drosophila melanogaster, GI18859849, Length=241, Percent_Identity=31.5352697095436, Blast_Score=105, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 62509; Mature: 62509

Theoretical pI: Translated: 7.31; Mature: 7.31

Prosite motif: PS50011 PROTEIN_KINASE_DOM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILQDLNRVRQITVIAARHGFGELAERAGLWRILGRKEKVEVSPEAQRASTARRFRMLLN
CCHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
DLGPTFVKLGQVLSTRADLLPAEYIDELAMLQDHVEPISLEDVRAQIEGSLGASVESLFA
HHCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHH
TIDSAPLAAASIAQVHRALTLEGEEVVVKVQRPGIAERIDSDLGVLRSLARLLEAVVEET
HHCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
GVYTLTGIVDEFDRAIHEELDFINEATNIRAFLENHRERPYLKIPRVYSGLSSRTVLTME
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCHHHCCCCCCHHHHHH
FIRGVKLNPAELSEPERKAIAQNILDASFRQLFEDGLFHGDPHPGNLLLLEDHRLALLDF
HHCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCEEEEHH
GVVGRLSRPMQETLVMLCLAVALKDSESVARILYRVGVPDARANLVGFRNDIEALLGQHL
HHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
TTTLGQVDTRSLLRDLLDLAVKYRIRIPKEYALLSRASVSTEGMLRSLYPEMNIIEVALP
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHH
YAKELLAGRYDPMQLQGGLMRTLLRFQAMAQDLPTQLSQILLDMESGKFTVTVRADQFEK
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHH
LNENLRSAAVIAFMGLCACGFIVGAFISFAPKPWMYGNVPVLGVVGIAVAAAFFGAAITW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
YLFGGRGLGKVRLSRFLKKPKRK
HHHCCCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure
MILQDLNRVRQITVIAARHGFGELAERAGLWRILGRKEKVEVSPEAQRASTARRFRMLLN
CCHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
DLGPTFVKLGQVLSTRADLLPAEYIDELAMLQDHVEPISLEDVRAQIEGSLGASVESLFA
HHCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHH
TIDSAPLAAASIAQVHRALTLEGEEVVVKVQRPGIAERIDSDLGVLRSLARLLEAVVEET
HHCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
GVYTLTGIVDEFDRAIHEELDFINEATNIRAFLENHRERPYLKIPRVYSGLSSRTVLTME
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCHHHCCCCCCHHHHHH
FIRGVKLNPAELSEPERKAIAQNILDASFRQLFEDGLFHGDPHPGNLLLLEDHRLALLDF
HHCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCEEEEHH
GVVGRLSRPMQETLVMLCLAVALKDSESVARILYRVGVPDARANLVGFRNDIEALLGQHL
HHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
TTTLGQVDTRSLLRDLLDLAVKYRIRIPKEYALLSRASVSTEGMLRSLYPEMNIIEVALP
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHH
YAKELLAGRYDPMQLQGGLMRTLLRFQAMAQDLPTQLSQILLDMESGKFTVTVRADQFEK
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHH
LNENLRSAAVIAFMGLCACGFIVGAFISFAPKPWMYGNVPVLGVVGIAVAAAFFGAAITW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
YLFGGRGLGKVRLSRFLKKPKRK
HHHCCCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA